Expression and function of the insulin receptor in normal and osteoarthritic human chondrocytes: Modulation of anabolic gene expression, glucose transport and GLUT-1 content by insulin

Osteoarthritis and Cartilage

Volumn 19, Issue 6, 2011, Pages 719-727

  Rosa, S C ^a,b   Rufino, A T ^a,b   Judas, F ^c,d   Tenreiro, C ^e   Lopes, M C ^a,b   Mendes, A F ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c CENTRO HOSPITALAR E UNIVERSITÁRIO DE COIMBRA   (Portugal)

^d UNIVERSITY OF COIMBRA   (Portugal)

^e UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Anabolic gene expression; Glucose transport; Human chondrocyte; Insulin; Insulin receptor; Insulin like growth factor receptor; Osteoarthritis

Indexed keywords

AGGRECAN; COLLAGEN TYPE 2; DEOXYGLUCOSE; GLUCOSE TRANSPORTER 1; INSULIN; INSULIN RECEPTOR; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3 KINASE; SOMATOMEDIN RECEPTOR;

ADULT; AGED; ARTICLE; ARTICULAR CARTILAGE; BINDING AFFINITY; CARTILAGE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE CONTROL; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MALE; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR BINDING; STAINING; TISSUE SECTION; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AGGRECANS; BLOTTING, WESTERN; CARTILAGE, ARTICULAR; CELLS, CULTURED; CHONDROCYTES; COLLAGEN; DEOXYGLUCOSE; FEMALE; GLUCOSE TRANSPORTER TYPE 1; HUMANS; INSULIN; MALE; MIDDLE AGED; OSTEOARTHRITIS; RECEPTOR, INSULIN; RNA, MESSENGER; YOUNG ADULT;

EID: 79955972378     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2011.02.004     Document Type: Article

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