Biological monitoring for occupational acrylamide exposure from acrylamide production workers

International Archives of Occupational and Environmental Health

Volumn 84, Issue 3, 2011, Pages 303-313

  Huang, Yu Fang ^a,b   Wu, Kuen Yuh ^c   Liou, Saou Hsing ^b   Uang, Shi Nian ^d   Chen, Chu Chih ^b   Shih, Wei Chung ^c   Lee, Shih Chuan ^d   Huang, Chih Chun Jean ^b   Chen, Mei Lien ^a  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d INSTITUTE OF OCCUPATIONAL SAFETY AND HEALTH   (Taiwan)

Author keywords

Acrylamide (AA); N acetyl S (1 carbamoyl 2 hydroxyethyl) cysteine (GAMA2); N acetyl S (2 carbamoyl 2 hydroxyethyl) cysteine (GAMA3); N acetyl S (2 carbamoylethyl) cysteine (AAMA); Occupational exposure; Repeated measurement

Indexed keywords

ACRYLAMIDE; ACRYLAMIDE DERIVATIVE;

ADULT; AIR POLLUTANT; ARTICLE; ELECTROSPRAY MASS SPECTROMETRY; ENVIRONMENTAL MONITORING; EXPOSURE; FEMALE; HALF LIFE TIME; HUMAN; MALE; MAXIMUM ALLOWABLE CONCENTRATION; METHODOLOGY; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SKIN ABSORPTION; TAIWAN; TANDEM MASS SPECTROMETRY; URINE;

ACRYLAMIDE; ACRYLAMIDES; ADULT; AIR POLLUTANTS, OCCUPATIONAL; ENVIRONMENTAL MONITORING; FEMALE; HALF-LIFE; HUMANS; INHALATION EXPOSURE; MALE; MAXIMUM ALLOWABLE CONCENTRATION; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SKIN ABSORPTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TAIWAN; TANDEM MASS SPECTROMETRY;

EID: 79955966753     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-010-0558-7     Document Type: Article

References (44)

1. American Conference of Governmental Industrial Hygienists (ACGIH) (2009) Threshold Limit Values and Biological Exposure Indices for 2009. ACGIH, Cincinnati, OH, USA
2. Bergmark E (1997) Hemoglobin adducts of acrylamide and acrylonitrile in laboratory workers, smokers and nonsmokers. Chem Res Toxicol 10:78-84 (Pubitemid 27044911)
3. Bergmark E, Calleman CJ, He FS et al (1993) Determination of hemoglobin adducts in humans occupationally exposed to acrylamide. Toxicol Appl Pharmacol 120:45-54 (Pubitemid 23156372)
4. Besaratinia A, Pfeifer GP (2005) DNA adduction and mutagenic properties of acrylamide. Mutat Res-Gen Tox En 80:31-40
5. Bjellaas T, Janak K, Lundanes E et al (2005) Determination and quantification of urinary metabolites after dietary exposure to acrylamide. Xenobiotica 35:1003-1018 (Pubitemid 43068044)
6. Bjellaas T, Stolen LH, Haugen M et al (2007) Urinary acrylamide metabolites as biomarkers for short-term dietary exposure to acrylamide. Food Chem Toxicol 45:1020-1026 (Pubitemid 46509818)
7. Boettcher MI, Schettgen T, Kutting B et al (2005) Mercapturic acids of acrylamide and glycidamide as biomarkers of the internal exposure to acrylamide in the general population. Mutat Res 580:167-176
8. Boettcher MI, Bolt HM, Drexler H et al (2006) Excretion of mercapturic acids of acrylamide and glycidamide in human urine after single oral administration of deuterium-labelled acrylamide. Arch Toxicol 80:55-61 (Pubitemid 43130229)
9. Bull PJ, Brooke RK, Cocker J et al (2005) An occupational hygiene investigation of exposure to acrylamide and the role for urinary S-carboxyethyl-cysteine (CEC) as a biological marker. Ann Occup Hyg 49:683-690 (Pubitemid 41668765)
10. Calleman CJ, Wu Y, He F et al (1994) Relationships between biomarkers of exposure and neurological effects in a group of workers exposed to acrylamide. Toxicol Appl Pharmacol 126:361-371
11. Council of Labor Affairs (CLA) (1993) Standards of permissible exposure limits of airborne hazardous substances in workplace. CLA, Executive Yuan, Taiwan
12. Deutsche Forschungsgemeinschaf (DFG) (2009) List of MAK and BAT values. Wieley-VCH Verlag, Weinheim
13. Doerge DR, Twaddle NC, Boettcher MI et al (2007) Urinary excretion of acrylamide and metabolites in Fischer 344 rats and B6C3F1 mice administered a single dose of acrylamide. Toxicol Lett 169:34-42 (Pubitemid 46215953)
14. Duale N, Bjellaas T, Alexander J et al (2009) Biomarkers of human exposure to acrylamide and relation to polymorphisms in metabolizing genes. Toxicol Sci 108:90-99
15. Fennell TR, Sumner SCJ, Snyder RW et al (2005) Metabolism and hemoglobin adduct formation of acrylamide in humans. Toxicol Sci 85:447-459 (Pubitemid 40614275)
16. Fennell TR, Sumner SCJ, Snyder RW et al (2006) Kinetics of elimination of urinary metabolites of acrylamide in humans. Toxicol Sci 93:256-267 (Pubitemid 44400444)
17. Fuhr U, Boettcher MI, Kinzig-Schippers M et al (2006) Toxicokinetics of acrylamide in humans after ingestion of a defined dose in a test meal to improve risk assessment for acrylamide carcinogenicity. Cancer Epidem Biomar 15:266-271 (Pubitemid 43342173)
18. Hagmar L, Tornqvist M, Nordander C et al (2001) Health effects of occupational exposure to acrylamide using hemoglobin adducts as biomarkers of internal dose. Scand J Work Env Hea 27:219-226 (Pubitemid 32830150)
19. Hartmann EC, Boettcher MI, Schettgen T et al (2008) Hemoglobin adducts and mercapturic acid excretion of acrylamide and glycidamide in one study population. J Agric Food Chem 56:6061-6068
20. Hartmann E, Boettcher M, Bolt H et al (2009) N-Acetyl-S-(1- carbamoyl-2-hydroxy-ethyl)-l-cysteine (iso-GAMA) a further product of human metabolism of acrylamide: comparison with the simultaneously excreted other mercapturic acids. Arch Toxicol 83:731-734
21. Huang CCJ, Li CM, Wu CF et al (2007) Analysis of urinary N-acetyl-S-(propionamide)-cysteine as a biomarker for the assessment of acrylamide exposure in smokers. Environ Res 104:346-351
22. International Agency for Research on Cancer (IARC) (1994) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: some industrial chemicals. 60: 389-433
23. Jaffe M (1886) Uber den niederschlag, welchen pikriksaure in normalen harn erzeugt und uber eine neue reaction des kreatinins. Z Physiol Chem 10:391
24. Jones K, Garfitt S, Emms V et al (2006) Correlation of haemoglobinacrylamide adducts with airborne exposure: an occupational survey. Toxicol Lett 162:174-180 (Pubitemid 43243138)
25. Kellert M, Scholz K, Wagner S et al (2006) Quantitation of mercapturic acids from acrylamide and glycidamide in human urine using a column switching tool with two trap columns and electrospray tandem mass spectrometry. J Chromatogr A 1131:58-66 (Pubitemid 44485656)
26. Kjuus H, Goffeng LO, Heier MS et al (2004) Effects on the peripheral nervous system of tunnel workers exposed to acrylamide and N-methylolacrylamide. Scand J Work Env Hea 30:21-29 (Pubitemid 38279449)
27. Kopp EK, Dekant W (2009) Toxicokinetics of acrylamide in rats and humans following single oral administration of low doses. Toxicol Appl Pharmacol 235:135-142
28. Kopp EK, Sieber M, Kellert M et al (2008) Rapid and sensitive HILIC-ESI-MS/MS quantitation of polar metabolites of acrylamide in human urine using column switching with an online trap column. J Agric Food Chem 56:9828-9834
29. Li CM, Hu CW, Wu KY (2005) Quantification of urinary N-acetyl-S- (propionamide)cysteine using an on-line clean-up system coupled with liquid chromatography/tandem mass spectrometry. J Mass Spectrom 40:511-555
30. National Safety Council (NSC) (2006) Chemical Backgrounders Index: Acrylamide. Available at http://www.environmentwriter.org/resources/backissues/ chemicals/acrylamide.htm. Accessed 22 June 22 2009
31. Occupational Safety Health Administration (OSHA) (1985) In OSHA Analytical Methods 21 Manual. Analytical Laboratory, Salt Lake City
32. Occupational Safety and Health Administration (OSHA) (2003) Sampling and analytical methods: Acrylamide, PV2004. Available at http://www.osha.gov/dts/ sltc/methods/partial/pv2004/2004.html. Accessed 22 June 22 2009
33. Pantusa VP, Stock TH, Morandi MT et al (2002) Inhalation exposures to acrylamide in biomedical laboratories. Am Ind Hyg Asso J 63:468-473
34. Schettgen T, Rossbach B, Kutting B et al (2004) Determination of haemoglobin adducts of acrylamide and glycidamide in smoking and non-smoking persons of the general population. Int J Hyg Enviro Heal 207:531-539 (Pubitemid 40824330)
35. Smith EA, Oehme FW (1991) Acrylamide and polyacrylamide: a review of production, use, environmental fate and neurotoxicity. Rev Environ Health 9:215-228
36. Smith CJ, Perfetti TA, Rumple MA et al (2000) "IARC Group 2A Carcinogens" reported in cigarette mainstream smoke. Food Chem Toxicol 38:371-383 (Pubitemid 30155498)
37. Sumner SC, MacNeela JP, Fennell TR (1992) Characterization and quantitation of urinary metabolites of [1, 2, 3-13C]acrylamide in rats and mice using 13C nuclear magnetic resonance spectroscopy. Chem Res Toxicol 5:81-89
38. Sumner SC, Selvaraj L, Nauhaus SK et al (1997) Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acrylonitrile for 1 or 5 days. Chem Res Toxicol 10:1152-1160 (Pubitemid 27449519)
39. Sumner SC, Fennell TR, Moore TA et al (1999) Role of cytochrome P450 2E1 in the metabolism of acrylamide and acrylonitrile in mice. Chem Res Toxicol 12:1110-1116
40. Tareke E, Rydberg P, Karlsson P et al (2002) Analysis of acrylamide, a carcinogen formed in heated foodstuffs. J Agric Food Chem 50:4998-5006 (Pubitemid 34856181)
41. Urban M, Kavvadias D, Riedel K et al (2006) Urinary Mercapturic acids and a hemoglobin adduct for the dosimetry of acrylamide exposure in smokers and nonsmokers. Inhal Toxicol 18:831-839
42. US Environmental Protection Agency (EPA) (1988) Preliminary assessment of health risks from exposure to acrylamide. Office of Toxic Substances. US EPA, Washington
43. Wu YQ, Yu AR, Tang XY et al (1993) Determination of acrylamide metabolite, mercapturic acid by high performance liquid chromatography. Biomed Environ Sci 6:273-280
44. Wu KY, Huang YF, Chen MF et al. (2010) Assessment of occupational exposure to airborne acrylamide by using an Isotope-dilution Gas Chromatagraphy-Mass Spectrometry Method. Ann Occup Hyg. doi:10.1093/annhyg/ meq010