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Volumn 117, Issue 16, 2011, Pages 4262-4272

An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT; HLA A2 ANTIGEN; IMMUNOGLOBULIN G2A ANTIBODY; PR1 ANTIGEN; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

EID: 79955966609     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2010-07-299248     Document Type: Article
Times cited : (102)

References (50)
  • 2
    • 0038780854 scopus 로고    scopus 로고
    • WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: Therapeutic potential of WT1 targeted therapies
    • DOI 10.1038/sj.leu.2402988
    • Rosenfeld C, Cheever MA, Gaiger A. WT1 in acute leukemia, chronic myelogenous leukemia and myelodysplastic syndrome: therapeutic potential of WT1 targeted therapies. Leukemia. 2003;17(7):1301-1312. (Pubitemid 36857337)
    • (2003) Leukemia , vol.17 , Issue.7 , pp. 1301-1312
    • Rosenfeld, C.1    Cheever, M.A.2    Gaiger, A.3
  • 4
    • 0033826799 scopus 로고    scopus 로고
    • Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia
    • Molldrem JJ, Lee PP, Wang C, et al. Evidence that specific T lymphocytes may participate in the elimination of chronic myelogenous leukemia. Nat Med. 2000;6(9):1018-1023.
    • (2000) Nat Med , vol.6 , Issue.9 , pp. 1018-1023
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3
  • 5
    • 77955624105 scopus 로고    scopus 로고
    • PR1-specific T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal
    • Kanodia S, Wieder E, Lu S, et al. PR1-specific T cells are associated with unmaintained cytogenetic remission of chronic myelogenous leukemia after interferon withdrawal. PLoS ONE. 2010; 5(7):e11770.
    • (2010) PLoS ONE , vol.5 , Issue.7
    • Kanodia, S.1    Wieder, E.2    Lu, S.3
  • 7
    • 38049188363 scopus 로고    scopus 로고
    • Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies
    • Rezvani K, Yong AS, Mielke S, et al. Leukemia-associated antigen-specific T-cell responses following combined PR1 and WT1 peptide vaccination in patients with myeloid malignancies. Blood. 2008;111(1):236-242.
    • (2008) Blood , vol.111 , Issue.1 , pp. 236-242
    • Rezvani, K.1    Yong, A.S.2    Mielke, S.3
  • 8
    • 0034678450 scopus 로고    scopus 로고
    • Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex
    • DOI 10.1084/jem.191.8.1395
    • Krogsgaard M, Wucherpfennig KW, Cannella B, et al. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2- MBP 85-99 complex. J Exp Med. 2000;191(8): 1395-1412. (Pubitemid 30227126)
    • (2000) Journal of Experimental Medicine , vol.191 , Issue.8 , pp. 1395-1412
    • Krogsgaard, M.1    Wucherpfennig, K.W.2    Canella, B.3    Hansen, B.E.4    Svejgaard, A.5    Pyrdol, J.6    Ditzel, H.7    Raine, C.8    Engberg, J.9    Fugger, L.10
  • 14
    • 49649129991 scopus 로고    scopus 로고
    • Targeting TARP, a novel breast and prostate tumorassociated antigen, with T cell receptor-like human recombinant antibodies
    • Epel M, Carmi I, Soueid-Baumgarten S, et al. Targeting TARP, a novel breast and prostate tumorassociated antigen, with T cell receptor-like human recombinant antibodies. Eur J Immunol. 2008;38(6):1706-1720.
    • (2008) Eur J Immunol , vol.38 , Issue.6 , pp. 1706-1720
    • Epel, M.1    Carmi, I.2    Soueid-Baumgarten, S.3
  • 15
    • 51049104493 scopus 로고    scopus 로고
    • Antitumor activity of immunotoxins with T-cell receptor- like specificity against human melanoma xenografts
    • Klechevsky E, Gallegos M, Denkberg G, et al. Antitumor activity of immunotoxins with T-cell receptor- like specificity against human melanoma xenografts. Cancer Res. 2008;68(15):6360-6367.
    • (2008) Cancer Res , vol.68 , Issue.15 , pp. 6360-6367
    • Klechevsky, E.1    Gallegos, M.2    Denkberg, G.3
  • 16
    • 77949895698 scopus 로고    scopus 로고
    • TCR mimic monoclonal antibody targets a specific peptide/HLA class I complex and significantly impedes tumor growth in vivo using breast cancer models
    • Verma B, Neethling FA, Caseltine S, et al. TCR mimic monoclonal antibody targets a specific peptide/HLA class I complex and significantly impedes tumor growth in vivo using breast cancer models. J Immunol. 184(4):2156-2165.
    • J Immunol , vol.184 , Issue.4 , pp. 2156-2165
    • Verma, B.1    Neethling, F.A.2    Caseltine, S.3
  • 17
    • 0030841573 scopus 로고    scopus 로고
    • Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units
    • Molldrem JJ, Clave E, Jiang YZ, et al. Cytotoxic T lymphocytes specific for a nonpolymorphic proteinase 3 peptide preferentially inhibit chronic myeloid leukemia colony-forming units. Blood. 1997; 90(7):2529-2534. (Pubitemid 27413460)
    • (1997) Blood , vol.90 , Issue.7 , pp. 2529-2534
    • Molldrem, J.J.1    Clave, E.2    Jiang, Y.Z.3    Mavroudis, D.4    Raptis, A.5    Hensel, N.6    Agarwala, V.7    Barrett, A.J.8
  • 19
    • 0033152972 scopus 로고    scopus 로고
    • A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low- Frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia
    • Molldrem JJ, Lee PP, Wang C, Champlin RE, Davis MM. A PR1-human leukocyte antigen-A2 tetramer can be used to isolate low-frequency cytotoxic T lymphocytes from healthy donors that selectively lyse chronic myelogenous leukemia. Cancer Res. 1999;59(11):2675-2681. (Pubitemid 29269115)
    • (1999) Cancer Research , vol.59 , Issue.11 , pp. 2675-2681
    • Molldrem, J.J.1    Lee, P.P.2    Wang, C.3    Champlin, R.E.4    Davis, M.M.5
  • 21
    • 33846258312 scopus 로고    scopus 로고
    • MHC-peptide tetramers to visualize antigen-specific T cells
    • Chapter 17:Unit 17.3.
    • Altman JD, Davis MM. MHC-peptide tetramers to visualize antigen-specific T cells. Curr Protoc Immunol. 2003;Chapter 17:Unit 17.3.
    • (2003) Curr Protoc Immunol
    • Altman, J.D.1    Davis, M.M.2
  • 23
    • 0029838112 scopus 로고    scopus 로고
    • Targeted T-cell therapy for human leukemia: Cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells
    • Molldrem J, Dermime S, Parker K, et al. Targeted T-cell therapy for human leukemia: cytotoxic T lymphocytes specific for a peptide derived from proteinase 3 preferentially lyse human myeloid leukemia cells. Blood. 1996;88(7):2450-2457. (Pubitemid 26327493)
    • (1996) Blood , vol.88 , Issue.7 , pp. 2450-2457
    • Molldrem, J.1    Dermime, S.2    Parker, K.3    Jiang, Y.Z.4    Mavroudis, D.5    Hensel, N.6    Fukushima, P.7    Barrett, A.J.8
  • 24
    • 70349247010 scopus 로고    scopus 로고
    • Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes
    • Hanley PJ, Cruz CR, Savoldo B, et al. Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood. 2009;114:1958-1967.
    • (2009) Blood , vol.114 , pp. 1958-1967
    • Hanley, P.J.1    Cruz, C.R.2    Savoldo, B.3
  • 25
    • 0026317416 scopus 로고
    • The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2
    • Bednarek MA, Sauma SY, Gammon MC, et al. The minimum peptide epitope from the influenza virus matrix protein. Extra and intracellular loading of HLA-A2. J Immunol. 1991;147(12):4047-4053.
    • (1991) J Immunol , vol.147 , Issue.12 , pp. 4047-4053
    • Bednarek, M.A.1    Sauma, S.Y.2    Gammon, M.C.3
  • 27
    • 65249176824 scopus 로고    scopus 로고
    • Rational development of high-affinity T-cell receptor-like antibodies
    • Stewart-Jones G, Wadle A, Hombach A, et al. Rational development of high-affinity T-cell receptor-like antibodies. Proc Natl Acad Sci U S A. 2009;106(14):5784-5788.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.14 , pp. 5784-5788
    • Stewart-Jones, G.1    Wadle, A.2    Hombach, A.3
  • 28
    • 0026729037 scopus 로고
    • Localization and characterization of serologic epitopes on HLA-A2
    • Hogan KT, Brown SL. Localization and characterization of serologic epitopes on HLA-A2. Hum Immunol. 1992;33(3):185-192.
    • (1992) Hum Immunol , vol.33 , Issue.3 , pp. 185-192
    • Hogan, K.T.1    Brown, S.L.2
  • 29
    • 0019285686 scopus 로고
    • A monoclonal antibody that recognizes an antigenic determinant shared by HLA A2 and B17
    • DOI 10.1016/0198-8859(80)90099-3
    • McMichael AJ, Parham P, Rust N, Brodsky F. A monoclonal antibody that recognizes an antigenic determinant shared by HLAA2 and B17. Hum Immunol. 1980;1(2):121-129. (Pubitemid 12238821)
    • (1980) Human Immunology , vol.1 , Issue.2 , pp. 121-129
    • McMichael, A.J.1    Parham, P.2    Rust, N.3    Brodsky, F.4
  • 30
    • 0023685879 scopus 로고
    • Molecular characterization of serologic recognition sites in the human HLA-A2 molecule
    • Santos-Aguado J, Barbosa JA, Biro PA, Strominger JL. Molecular characterization of serologic recognition sites in the human HLA-A2 molecule. J Immunol. 1988;141(8):2811-2818. (Pubitemid 18263073)
    • (1988) Journal of Immunology , vol.141 , Issue.8 , pp. 2811-2818
    • Santos-Aguado, J.1    Barbosa, J.A.2    Biro, P.A.3    Strominger, J.L.4
  • 31
    • 0028334588 scopus 로고
    • Both major and minor peptide-binding pockets in HLA-A2 influence the presentation of influenza virus matrix peptide to cytotoxic T lymphocytes
    • DOI 10.1016/0161-5890(94)90065-5
    • Teng JM, Hogan KT. Both major and minor peptide- binding pockets in HLA-A2 influence the presentation of influenza virus matrix peptide to cytotoxic T lymphocytes. Mol Immunol. 1994;31(6): 459-470. (Pubitemid 24153330)
    • (1994) Molecular Immunology , vol.31 , Issue.6 , pp. 459-470
    • Teng, J.M.C.1    Hogan, K.T.2
  • 32
    • 0028335803 scopus 로고
    • Residues outside of the HLA-A2 peptide-binding groove can abrogate or enhance recognition of influenza virus matrix peptide pulsed cells by cytotoxic T lymphocytes
    • DOI 10.1016/0161-5890(94)90064-7
    • Teng JM, Hogan KT. Residues outside of the HLA-A2 peptide-binding groove can abrogate or enhance recognition of influenza virus matrix peptide pulsed cells by cytotoxic T lymphocytes. Mol Immunol. 1994;31(6):445-457. (Pubitemid 24153329)
    • (1994) Molecular Immunology , vol.31 , Issue.6 , pp. 445-457
    • Teng, J.M.C.1    Hogan, K.T.2
  • 34
    • 0026754577 scopus 로고
    • Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter
    • Zimmer M, Medcalf RL, Fink TM, Mattmann C, Lichter P, Jenne DE. Three human elastase-like genes coordinately expressed in the myelomonocyte lineage are organized as a single genetic locus on 19pter. Proc Natl Acad Sci U S A. 1992; 89(17):8215-8219.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , Issue.17 , pp. 8215-8219
    • Zimmer, M.1    Medcalf, R.L.2    Fink, T.M.3    Mattmann, C.4    Lichter, P.5    Jenne, D.E.6
  • 35
    • 0028153951 scopus 로고
    • The phylogeny of proteinase 3/myeloblastin, the autoantigen in Wegener's granulomatosis, and myeloperoxidase as shown by immunohistochemical studies on human leukemic cell lines
    • DOI 10.1006/clin.1994.1010
    • Muller-Bérat N, Minowada J, Tsuji-Takayama K, et al. The phylogeny of proteinase 3/myeloblastin, the autoantigen in Wegener's granulomatosis, and myeloperoxidase as shown by immunohistochemical studies on human leukemic cell lines. Clin Immunol Immunopathol. 1994;70(1):51-59. (Pubitemid 24034689)
    • (1994) Clinical Immunology and Immunopathology , vol.70 , Issue.1 , pp. 51-59
    • Muller-Berat, N.1    Minowada, J.2    Tsuji-Takayama, K.3    Drexler, H.4    Lanotte, M.5    Wieslander, J.6    Wiik, A.7
  • 36
    • 0028203752 scopus 로고
    • The heterogeneity of azurophil granules in neutrophil promyelocytes: Immunogold localization of myeloperoxidase, cathepsin G, elastase, proteinase 3, and bactericidal/permeability increasing protein
    • Egesten A, Breton-Gorius J, Guichard J, Gullberg U, Olsson I. The heterogeneity of azurophil granules in neutrophil promyelocytes: immunogold localization of myeloperoxidase, cathepsin G, elastase, proteinase 3, and bactericidal/permeability increasing protein. Blood. 1994;83(10):2985-2994. (Pubitemid 24142733)
    • (1994) Blood , vol.83 , Issue.10 , pp. 2985-2994
    • Egesten, A.1    Breton-Gorius, J.2    Guichard, J.3    Gullberg, U.4    Olsson, I.5
  • 37
    • 0029730784 scopus 로고    scopus 로고
    • Human proteinase-3 expression is regulated by PU.1 in conjunction with a cytidine-rich element
    • DOI 10.1074/jbc.271.50.32392
    • Sturrock A, Franklin KF, Hoidal JR. Human proteinase-3 expression is regulated by PU.1 in conjunction with a cytidine-rich element. J Biol Chem. 1996;271(50):32392-32402. (Pubitemid 26422282)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.50 , pp. 32392-32402
    • Sturrock, A.1    Franklin, K.F.2    Hoidal, J.R.3
  • 38
    • 1542300936 scopus 로고    scopus 로고
    • Activation of human mast cells by aggregated IgG through FcγRI: Additive effects of C3a
    • DOI 10.1016/j.clim.2003.11.007, PII S152166160300319X
    • Woolhiser MR, Brockow K, Metcalfe DD. Activation of human mast cells by aggregated IgG through FcgammaRI: additive effects of C3a. Clin Immunol. 2004;110(2):172-180. (Pubitemid 38296707)
    • (2004) Clinical Immunology , vol.110 , Issue.2 , pp. 172-180
    • Woolhiser, M.R.1    Brockow, K.2    Metcalfe, D.D.3
  • 39
    • 3142564395 scopus 로고    scopus 로고
    • Three new assays for rituximab based on its immunological activity or antigenic properties: Analyses of sera and plasmas of RTX-treated patients with chronic lymphocytic leukemia and other B cell lymphomas
    • DOI 10.1016/j.jim.2004.03.012, PII S0022175904001206
    • Beum PV, Kennedy AD, Taylor RP. Three new assays for rituximab based on its immunological activity or antigenic properties: analyses of sera and plasmas of RTX-treated patients with chronic lymphocytic leukemia and other B cell lymphomas. J Immunol Methods. 2004;289(1-2):97-109. (Pubitemid 38900908)
    • (2004) Journal of Immunological Methods , vol.289 , Issue.1-2 , pp. 97-109
    • Beum, P.V.1    Kennedy, A.D.2    Taylor, R.P.3
  • 41
    • 3242754448 scopus 로고    scopus 로고
    • Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity
    • DOI 10.1038/ni1080
    • Hope KJ, Jin L, Dick JE. Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity. Nat Immunol. 2004;5(7):738-743. (Pubitemid 39023306)
    • (2004) Nature Immunology , vol.5 , Issue.7 , pp. 738-743
    • Hope, K.J.1    Jin, L.2    Dick, J.E.3
  • 42
    • 0035499267 scopus 로고    scopus 로고
    • Stem cells, cancer, and cancer stem cells
    • DOI 10.1038/35102167
    • Reya T, Morrison SJ, Clarke MF, Weissman IL. Stem cells, cancer, and cancer stem cells. Nature. 2001;414(6859):105-111. (Pubitemid 33041634)
    • (2001) Nature , vol.414 , Issue.6859 , pp. 105-111
    • Reya, T.1    Morrison, S.J.2    Clarke, M.F.3    Weissman, I.L.4
  • 43
    • 0011184968 scopus 로고
    • Induction of immune cytolysis: Tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase
    • Vogel CW, Muller-Eberhard HJ. Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase. Proc Natl Acad Sci U S A. 1981;78(12):7707-7711. (Pubitemid 12186631)
    • (1981) Proceedings of the National Academy of Sciences of the United States of America , vol.78 , Issue.12 II , pp. 7707-7711
    • Vogel, C.-W.1    Muller-Eberhard, H.J.2
  • 44
    • 35348827319 scopus 로고    scopus 로고
    • Monoclonal antibody mechanisms of action in cancer
    • DOI 10.1007/s12026-007-0073-4
    • Weiner GJ. Monoclonal antibody mechanisms of action in cancer. Immunol Res. 2007;39(1-3):271-278. (Pubitemid 47574893)
    • (2007) Immunologic Research , vol.39 , Issue.1-3 , pp. 271-278
    • Weiner, G.J.1
  • 45
    • 33745238056 scopus 로고    scopus 로고
    • A new anticancer glycolipid monoclonal antibody, SC104, which directly induces tumor cell apoptosis
    • DOI 10.1158/0008-5472.CAN-05-3812
    • Durrant LG, Harding SJ, Green NH, Buckberry LD, Parsons T. A new anticancer glycolipid monoclonal antibody, SC104, which directly induces tumor cell apoptosis. Cancer Res. 2006;66(11): 5901-5909. (Pubitemid 43927145)
    • (2006) Cancer Research , vol.66 , Issue.11 , pp. 5901-5909
    • Durrant, L.G.1    Harding, S.J.2    Green, N.H.3    Buckberry, L.D.4    Parsons, T.5
  • 46
    • 41249094682 scopus 로고    scopus 로고
    • Detection of CD55- and CD59-deficient granulocytic populations in patients with myelodysplastic syndrome
    • Kaiafa G, Papadopoulos A, Ntaios G, et al. Detection of CD55- and CD59-deficient granulocytic populations in patients with myelodysplastic syndrome. Ann Hematol. 2008;87(4):257-262.
    • (2008) Ann Hematol , vol.87 , Issue.4 , pp. 257-262
    • Kaiafa, G.1    Papadopoulos, A.2    Ntaios, G.3
  • 47
    • 0033957848 scopus 로고    scopus 로고
    • Expression of complement regulatory proteins CR1, DAF, MCP and CD59 in haematological malignancies
    • DOI 10.1034/j.1600-0609.2000.80097.x
    • Guc D, Canpinar H, Kucukaksu C, Kansu E. Expression of complement regulatory proteins CR1, DAF, MCP and CD59 in haematological malignancies. Eur J Haematol. 2000;64(1):3-9. (Pubitemid 30055538)
    • (2000) European Journal of Haematology , vol.64 , Issue.1 , pp. 3-9
    • Guc, D.1    Canpinar, H.2    Kucukaksu, C.3    Kansu, E.4
  • 48
    • 0029942666 scopus 로고    scopus 로고
    • Mechanisms by which the surface expression of the glycosyl- phosphatidylinositol-anchored complement regulatory proteins decay-accelerating factor (CD55) and CD59 is lost in human leukaemia cell lines
    • Hatanaka M, Seya T, Matsumoto M, et al. Mechanisms by which the surface expression of the glycosyl-phosphatidylinositol-anchored complement regulatory proteins decay-accelerating factor (CD55) and CD59 is lost in human leukaemia cell lines. Biochem J. 1996;314(pt 3):969-976.
    • (1996) Biochem J , vol.314 , Issue.PART 3 , pp. 969-976
    • Hatanaka, M.1    Seya, T.2    Matsumoto, M.3
  • 49
    • 0033736036 scopus 로고    scopus 로고
    • TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function
    • Jacobs H. TCR-independent T cell development mediated by gain-of-oncogene function or loss-of-tumor-suppressor gene function. Semin Immunol. 2000;12(5):487-502.
    • (2000) Semin Immunol , vol.12 , Issue.5 , pp. 487-502
    • Jacobs, H.1
  • 50
    • 0042971650 scopus 로고    scopus 로고
    • Molecular interactions mediating T cell antigen recognition
    • DOI 10.1146/annurev.immunol.21.120601.141036
    • van der Merwe PA, Davis SJ. Molecular interactions mediating T cell antigen recognition. Annu Rev Immunol. 2003;21:659-684. (Pubitemid 37174544)
    • (2003) Annual Review of Immunology , vol.21 , pp. 659-684
    • Van Der, M.P.A.1    Davis, S.J.2


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