Direct selection of a human antibody fragment directed against the tumor T-cell epitope HLA-A1-MAGE-A1 from a nonimmunized phage-Fab library

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 14, 2000, Pages 7969-7974

  Chames, Patrick ^b   Hufton, Simon E ^c   Coulie, Pierre G ^d   Uchanska Ziegler, Barbara ^e   Hoogenboom, Hennie R ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Target Quest BV   (Netherlands)

^d UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^e CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Major histocompatibility complex; Phage display; T cell antigen receptor like antibodies; Tumor targeting

Indexed keywords

ANTIGEN MAGE A1; CANCER ANTIBODY; EPITOPE; HLA A1 ANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MELANOMA ANTIGEN; RECOMBINANT ANTIBODY; T LYMPHOCYTE RECEPTOR; TUMOR VACCINE; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY COMPLEX; ANTIGENICITY; ARTICLE; BIOTINYLATION; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; HUMAN; HUMAN CELL; IN VITRO STUDY; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN FOLDING;

ANTIBODIES, NEOPLASM; ANTIGEN PRESENTATION; ANTIGENS, DIFFERENTIATION; BIOSENSING TECHNIQUES; CLONING, MOLECULAR; EPITOPES; FLOW CYTOMETRY; HLA-A1 ANTIGEN; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; MELANOMA; NEOPLASM PROTEINS; PEPTIDE LIBRARY; PROTEIN FOLDING; SELECTION (GENETICS); T-LYMPHOCYTES;

EID: 0034608939     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.14.7969     Document Type: Article

References (55)