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Volumn 12, Issue 8, 2011, Pages 1203-1208

Mechanism-Based Inhibition of Quinone Reductase 2 (NQO2): Selectivity for NQO2 over NQO1 and Structural Basis for Flavoprotein Inhibition

(12) Dufour, Marine a Yan, Chao b Siegel, David b Colucci, Marie A a Jenner, Matthew a Oldham, Neil J a Gomez, Joe b Reigan, Philip b Li, Yazhuo a De Matteis, Cristina I a Ross, David b Moody, Christopher J a

a UNIVERSITY OF NOTTINGHAM (United Kingdom)

b UNIVERSITY OF COLORADO (United States)

Author keywords

Enzymes; Inhibitors; Protein structure; Quinones; Redox chemistry

Indexed keywords

FLAVOPROTEIN; INDOLE DERIVATIVE; QUINONE REDUCTASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG;

ARTICLE; ENZYME INHIBITION; HUMAN; HUMAN CELL; MASS SPECTROMETRY; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN TARGETING; STRUCTURE ACTIVITY RELATION; X RAY CRYSTALLOGRAPHY;

CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; FLAVOPROTEINS; HUMANS; INDOLEQUINONES; MOLECULAR STRUCTURE; NAD(P)H DEHYDROGENASE (QUINONE); QUINONE REDUCTASES; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY;

EID: 79955956545 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201100085 Document Type: Article

Times cited : (20)

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