-
1
-
-
77949267597
-
Evolving paradigms in the pathogenesis of IBD
-
Mayer L. Evolving paradigms in the pathogenesis of IBD. J Gastroenterol 2010;45:9-16.
-
(2010)
J. Gastroenterol.
, vol.45
, pp. 9-16
-
-
Mayer, L.1
-
2
-
-
40149092512
-
Inflammatory bowel disease, past, present and future: Lessons from animal models
-
DOI 10.1007/s00535-007-2111-3
-
Mizoguchi A, Mizoguchi E. Inflammatory bowel disease, past, present and future: lessons from animal models. J Gastroenterol 2008;43:1-17. (Pubitemid 351324980)
-
(2008)
Journal of Gastroenterology
, vol.43
, Issue.1
, pp. 1-17
-
-
Mizoguchi, A.1
Mizoguchi, E.2
-
3
-
-
77955708883
-
New pathophysiological insights and modern treatment of IBD
-
Engel MA, Neurath MF. New pathophysiological insights and modern treatment of IBD. J Gastroenterol 2010;45: 571-83.
-
(2010)
J. Gastroenterol.
, vol.45
, pp. 571-583
-
-
Engel, M.A.1
Neurath, M.F.2
-
4
-
-
0031781603
-
Inflammatory bowel disease: Etiology and pathogenesis
-
DOI 10.1016/S0016-5085(98)70381-6
-
Fiocchi C. Inflammatory bowel disease: etiology and pathogenesis. Gastroenterology 1998;115:182-205. (Pubitemid 28307304)
-
(1998)
Gastroenterology
, vol.115
, Issue.1
, pp. 182-205
-
-
Fiocchi, C.1
-
5
-
-
67449147595
-
Interleukin-23/Th17 pathways and inflammatory bowel disease
-
Abraham C, Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm Bowel Dis 2009;15: 1090-100.
-
(2009)
Inflamm. Bowel. Dis.
, vol.15
, pp. 1090-1100
-
-
Abraham, C.1
Cho, J.2
-
6
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and crohns disease
-
Kobayashi T, Okamoto S, Hisamatsu T, Kamada N, Chinen H, Saito R, et al. IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 2008;57:1682-9.
-
(2008)
Gut.
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
Kamada, N.4
Chinen, H.5
Saito, R.6
-
7
-
-
0037203867
-
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
-
DOI 10.1038/415536a
-
Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, et al. Th1-specific cell surface protein Tim-3- regulates macrophage activation and severity of an autoimmune disease. Nature 2002;415:536-41. (Pubitemid 34130609)
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 536-541
-
-
Monney, L.1
Sabatos, C.A.2
Gaglia, J.L.3
Ryu, A.4
Waldner, H.5
Chernova, T.6
Manning, S.7
Greenfield, E.A.8
Coyle, A.J.9
Sobel, R.A.10
Freeman, G.J.11
Kuchroo, V.K.12
-
8
-
-
0242539820
-
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
-
DOI 10.1038/ni988
-
Sabatos CA, Chakravarti S, Cha E, Schubart A, Sánchez- Fueyo A, Zheng XX, et al. Interaction of Tim-3 and Tim-3- ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol 2003;4:1102-10. (Pubitemid 37428038)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1102-1110
-
-
Sabatos, C.A.1
Chakravarti, S.2
Cha, E.3
Schubart, A.4
Sanchez-Fueyo, A.5
Zheng, X.X.6
Coyle, A.J.7
Strom, T.B.8
Freeman, G.J.9
Kuchroo, V.K.10
-
9
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
DOI 10.1038/ni987
-
Sánchez-Fueyo A, Tian J, Picarella D, Domenig C, Zheng XX, Sabatos CA, et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol 2003;4: 1093-101. (Pubitemid 37428037)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
Domenig, C.4
Zheng, X.X.5
Sabatos, C.A.6
Manlongat, N.7
Bender, O.8
Kamradt, T.9
Kuchroo, V.K.10
Gutierrez-Ramos, J.-C.11
Coyle, A.J.12
Strom, T.B.13
-
10
-
-
36248967595
-
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
-
DOI 10.1126/science.1148536
-
Anderson AC, Anderson DE, Bregoli L, Hastings WD, Kassam N, Lei C, et al. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 2007;318:1141-3. (Pubitemid 350134897)
-
(2007)
Science
, vol.318
, Issue.5853
, pp. 1141-1143
-
-
Anderson, A.C.1
Anderson, D.E.2
Bregoli, L.3
Hastings, W.D.4
Kassam, N.5
Lei, C.6
Chandwaskar, R.7
Karman, J.8
Su, E.W.9
Hirashima, M.10
Bruce, J.N.11
Kane, L.P.12
Kuchroo, V.K.13
Hafler, D.A.14
-
11
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
DOI 10.1084/jem.20041257
-
Langrish CL, Chen Y, Blumenschein WM, Mattson J, Basham B, Sedgwick JD, et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005;201:233-40. (Pubitemid 40189432)
-
(2005)
Journal of Experimental Medicine
, vol.201
, Issue.2
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
13
-
-
34648846718
-
Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts
-
DOI 10.1007/s00535-007-2091-3
-
Yagi Y, Andoh A, Inatomi O, Tsujikawa T, Fujiyama Y. Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts. J Gastroenterol 2007;42:746-53. (Pubitemid 47456762)
-
(2007)
Journal of Gastroenterology
, vol.42
, Issue.9
, pp. 746-753
-
-
Yagi, Y.1
Andoh, A.2
Inatomi, O.3
Tsujikawa, T.4
Fujiyama, Y.5
-
14
-
-
33745873727
-
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis
-
DOI 10.1084/jem.20060285
-
Sutton C, Brereton C, Keogh B, Mills KH, Lavelle EC. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 2006;203:1685-91. (Pubitemid 44036274)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.7
, pp. 1685-1691
-
-
Sutton, C.1
Brereton, C.2
Keogh, B.3
Mills, K.H.G.4
Lavelle, E.C.5
-
15
-
-
33846456970
-
+ Th cells that cause autoimmune arthritis
-
DOI 10.1084/jem.20062259
-
Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, et al. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J Exp Med 2007;204: 41-7. (Pubitemid 46148754)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.1
, pp. 41-47
-
-
Hirota, K.1
Hashimoto, M.2
Yoshitomi, H.3
Tanaka, S.4
Nomura, T.5
Yamaguchi, T.6
Iwakura, Y.7
Sakaguchi, N.8
Sakaguchi, S.9
-
16
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J Clin Invest 2006;116: 1317-26.
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.6
-
17
-
-
30044434075
-
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
-
DOI 10.1038/ni1271, PII N1271
-
Zhu C, Anderson AC, Schubart A, Xiong H, Imitola J, Khoury SJ, et al. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 2005;6: 1245-52. (Pubitemid 43045636)
-
(2005)
Nature Immunology
, vol.6
, Issue.12
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
Khoury, S.J.6
Zheng, X.X.7
Strom, T.B.8
Kuchroo, V.K.9
-
19
-
-
33745035874
-
Dysregulated T cell expression of TIM3 in multiple sclerosis
-
DOI 10.1084/jem.20060210
-
Koguchi K, Anderson DE, Yang L, O'Connor KC, Kuchroo VK, Hafler DA. Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med 2006;203: 1413-18. (Pubitemid 43877603)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.6
, pp. 1413-1418
-
-
Koguchi, K.1
Anderson, D.E.2
Yang, L.3
O'Connor, K.C.4
Kuchroo, V.K.5
Hafler, D.A.6
-
20
-
-
36749068417
-
Expression of human TIM-1 and TIM-3 on lymphocytes from systemic lupus erythematosus patients
-
DOI 10.1111/j.1365-3083.2007.02038.x
-
Wang Y, Meng J, Wang X, Liu S, Shu Q, Gao L, et al. Expression of human TIM-1 and TIM-3 on lymphocytes from systemic lupus erythematosus patients. Scand J Immunol 2008;67:63-70. (Pubitemid 350209587)
-
(2008)
Scandinavian Journal of Immunology
, vol.67
, Issue.1
, pp. 63-70
-
-
Wang, Y.1
Meng, J.2
Wang, X.3
Liu, S.4
Shu, Q.5
Gao, L.6
Ju, Y.7
Zhang, L.8
Sun, W.9
Ma, C.10
-
21
-
-
73349083370
-
Involvement of T cell Ig Mucin-3 Tim-3 in the negative regulation of inflammatory bowel disease
-
Li X, Chen G, Li Y, Wang R, Wang L, Lin Z, et al. Involvement of T cell Ig Mucin-3 (Tim-3) in the negative regulation of inflammatory bowel disease. Clin Immunol 2010;134:169-77.
-
(2010)
Clin. Immunol.
, vol.134
, pp. 169-177
-
-
Li, X.1
Chen, G.2
Li, Y.3
Wang, R.4
Wang, L.5
Lin, Z.6
-
22
-
-
0017227303
-
Development of a crohns disease activity index national cooperative crohns disease study
-
Best WR, Becktel JM, Singleton JW, Kern F Jr. Development of a Crohn's disease activity index. National Cooperative Crohn's Disease Study. Gastroenterology 1976;70: 439-44.
-
(1976)
Gastroenterology
, vol.70
, pp. 439-444
-
-
Best, W.R.1
Becktel, J.M.2
Singleton, J.W.3
Kern Jt., F.4
-
23
-
-
0023521441
-
Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis: A randomized study
-
Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 1987; 317:1625-9. (Pubitemid 18010466)
-
(1987)
New England Journal of Medicine
, vol.317
, Issue.26
, pp. 1625-1629
-
-
Schroeder, K.W.1
Tremaine, W.J.2
Ilstrup, D.M.3
-
24
-
-
2442704124
-
T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
-
Khademi M, Illés Z, Gielen AW, Marta M, Takazawa N, Baecher-Allan C, et al. T cell Ig- and mucin-domaincontaining molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J Immunol 2004;172:7169-76. (Pubitemid 38669161)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
, pp. 7169-7176
-
-
Khademi, M.1
Illes, Z.2
Gielen, A.W.3
Marta, M.4
Takazawa, N.5
Baecher-Allan, C.6
Brundin, L.7
Hannerz, J.8
Martin, C.9
Harris, R.A.10
Hafler, D.A.11
Kuchroo, V.K.12
Olsson, T.13
Piehl, F.14
Wallstrom, E.15
-
25
-
-
77749304012
-
T-bet a Th1 transcription factor regulates the expression of Tim-3
-
Anderson AC, Lord GM, Dardalhon V, Lee DH, Sabatos- Peyton CA, Glimcher LH, et al. T-bet, a Th1 transcription factor regulates the expression of Tim-3. Eur J Immunol 2010;40:859-66.
-
(2010)
Eur. J. Immunol.
, vol.40
, pp. 859-866
-
-
Anderson, A.C.1
Lord, G.M.2
Dardalhon, V.3
Lee, D.H.4
Sabatos-Peyton, C.A.5
Glimcher, L.H.6
-
26
-
-
0028809507
-
Expression of costimulatory molecules B7-1 CD80 B7-2 CD86 and interleukin 12 cytokine in multiple sclerosis lesions
-
Windhagen A, Newcombe J, Dangond F, Strand C, Woodroofe MN, Cuzner ML, et al. Expression of costimulatory molecules B7-1 (CD80), B7-2 (CD86), and interleukin 12 cytokine in multiple sclerosis lesions. J Exp Med 1995;182:1985-96.
-
(1995)
J. Exp. Med.
, vol.182
, pp. 1985-1996
-
-
Windhagen, A.1
Newcombe, J.2
Dangond, F.3
Strand, C.4
Woodroofe, M.N.5
Cuzner, M.L.6
-
27
-
-
70349248367
-
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
-
Hastings WD, Anderson DE, Kassam N, Koguchi K, Greenfield EA, Kent SC, et al. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol 2009;39:2492-501.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 2492-2501
-
-
Hastings, W.D.1
Anderson, D.E.2
Kassam, N.3
Koguchi, K.4
Greenfield, E.A.5
Kent, S.C.6
-
28
-
-
0028361570
-
Th1-Th2 paradigm: Insights from leprosy
-
Modlin RL. Th1-Th2 paradigm: insights from leprosy. J Invest Dermatol 1994;102:828-32. (Pubitemid 24210374)
-
(1994)
Journal of Investigative Dermatology
, vol.102
, Issue.6
, pp. 828-832
-
-
Modlin, R.L.1
-
29
-
-
0026012259
-
Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones
-
Salgame P, Abrams JS, Clayberger C, Goldstein H, Convit J, Modlin RL, et al. Differing lymphokine profiles of functional subsets of human CD4 and CD8 T cell clones. Science 1991; 254:279-82. (Pubitemid 21917341)
-
(1991)
Science
, vol.254
, Issue.5029
, pp. 279-282
-
-
Salgame, P.1
Abrams, J.S.2
Clayberger, C.3
Goldstein, H.4
Convit, J.5
Modlin, R.L.6
Bloom, B.R.7
-
30
-
-
0030746897
-
Th1-Th2: Reliable paradigm or dangerous dogma?
-
DOI 10.1016/S0167-5699(97)01102-X, PII S016756999701102X
-
Allen JE, Maizels RM. Th1-Th2: reliable paradigm or dangerous dogma? Immunol Today 1997;18:387-92. (Pubitemid 27315712)
-
(1997)
Immunology Today
, vol.18
, Issue.8
, pp. 387-392
-
-
Allen, J.E.1
Maizels, R.M.2
-
31
-
-
0035451044
-
Th1- or Th2-cell commitment during infectious disease: An oversimplification?
-
DOI 10.1016/S1471-4906(01)01980-9, PII S1471490601019809
-
Rook G. Th1- or Th2-cell commitment during infectious disease: an oversimplification? Trends Immunol 2001;22: 481-2. (Pubitemid 32778574)
-
(2001)
Trends in Immunology
, vol.22
, Issue.9
, pp. 481-482
-
-
Rook, G.1
-
32
-
-
18644386263
-
Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells
-
Imaizumi T, Kumagai M, Sasaki N, Kurotaki H, Mori F, Seki M, et al. Interferon-gamma stimulates the expression of galectin-9 in cultured human endothelial cells. J Leukoc Biol 2002;72:486-91.
-
(2002)
J. Leukoc. Biol.
, vol.72
, pp. 486-491
-
-
Imaizumi, T.1
Kumagai, M.2
Sasaki, N.3
Kurotaki, H.4
Mori, F.5
Seki, M.6
-
33
-
-
77956409684
-
Tim-3/galectin-9 pathway: Regulation of Th1 immunity through promotion of CD11b +Ly-6G+ myeloid cells
-
Dardalhon V, Anderson AC, Karman J, Apetoh L, Chandwaskar R, Lee DH, et al. Tim-3/galectin-9 pathway: regulation of Th1 immunity through promotion of CD11b +Ly-6G+ myeloid cells. J Immunol 2010;185:1383-92.
-
(2010)
J. Immunol.
, vol.185
, pp. 1383-1392
-
-
Dardalhon, V.1
Anderson, A.C.2
Karman, J.3
Apetoh, L.4
Chandwaskar, R.5
Lee, D.H.6
-
34
-
-
37549016755
-
The production of interferongamma-inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity
-
Noguchi A, Watanabe K, Narumi S, Yamagami H, Fujiwara Y, Higuchi K, et al. The production of interferongamma- inducible protein 10 by granulocytes and monocytes is associated with ulcerative colitis disease activity. J Gastroenterol 2007;42:947-56.
-
(2007)
J. Gastroenterol.
, vol.42
, pp. 947-956
-
-
Noguchi, A.1
Watanabe, K.2
Narumi, S.3
Yamagami, H.4
Fujiwara, Y.5
Higuchi, K.6
-
35
-
-
0031048272
-
Identification and characterization of galectin-9, a novel β- galactoside-binding mammalian lectin
-
DOI 10.1074/jbc.272.9.6078
-
Wada J, Kanwar YS. Identification and characterization of galectin-9, a novel beta-galactoside-binding mammalian lectin. J Biol Chem 1997;272:6078-86. (Pubitemid 27102450)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.9
, pp. 6078-6086
-
-
Wada, J.1
Kanwar, Y.S.2
-
36
-
-
77951673268
-
TIM genes: A family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
-
Freeman GJ, Casasnovas JM, Umetsu DT, DeKruyff RH. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol Rev 2010;235:172-89.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 172-189
-
-
Freeman, G.J.1
Casasnovas, J.M.2
Umetsu, D.T.3
DeKruyff, R.H.4
-
37
-
-
77957322877
-
Increased Tim-3 expression on peripheral lymphocytes from patients with rheumatoid arthritis negatively correlates with disease activity
-
Liu Y, Shu Q, Gao L, Hou N, Zhao D, Liu X, et al. Increased Tim-3 expression on peripheral lymphocytes from patients with rheumatoid arthritis negatively correlates with disease activity. Clin Immunol 2010;137:288-95.
-
(2010)
Clin. Immunol.
, vol.137
, pp. 288-295
-
-
Liu, Y.1
Shu, Q.2
Gao, L.3
Hou, N.4
Zhao, D.5
Liu, X.6
-
38
-
-
67349138187
-
The role of T-cell immunoglobulin-and mucin-domaincontaining molecule-3 polymorphisms in idiopathic thrombocytopenic purpura
-
Du WT, Zhao HF, Xu JH, Gu DS, Xue F, Ge J, et al. The role of T-cell immunoglobulin- and mucin-domaincontaining molecule-3 polymorphisms in idiopathic thrombocytopenic purpura. Hum Immunol 2009;70:398-402.
-
(2009)
Hum. Immunol.
, vol.70
, pp. 398-402
-
-
Du, W.T.1
Zhao, H.F.2
Xu, J.H.3
Gu, D.S.4
Xue, F.5
Ge, J.6
|