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Volumn 589, Issue 10, 2011, Pages 2475-2496

Knocking down of the KCC2 in rat hippocampal neurons increases intracellular chloride concentration and compromises neuronal survival

Author keywords

[No Author keywords available]

Indexed keywords

CHLORIDE ION; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; POTASSIUM CHLORIDE COTRANSPORTER; POTASSIUM CHLORIDE COTRANSPORTER 2; UNCLASSIFIED DRUG;

EID: 79955944363     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.203703     Document Type: Article
Times cited : (79)

References (70)
  • 1
    • 0034955064 scopus 로고    scopus 로고
    • Multiple-label immunocytochemistry for the evaluation of nature of cell death in experimental models of neurodegeneration
    • Adamec E, Yang F, Cole GM & Nixon RA (2001). Multiple-label immunocytochemistry for the evaluation of nature of cell death in experimental models of neurodegeneration. Brain Res Brain Res Protoc 7, 193-202.
    • (2001) Brain Res Brain Res Protoc , vol.7 , pp. 193-202
    • Adamec, E.1    Yang, F.2    Cole, G.M.3    Nixon, R.A.4
  • 2
    • 33646912707 scopus 로고    scopus 로고
    • Depolarizing GABAergic conductances regulate the balance of excitation to inhibition in the developing retinotectal circuit in vivo
    • Akerman CJ & Cline HT (2006). Depolarizing GABAergic conductances regulate the balance of excitation to inhibition in the developing retinotectal circuit in vivo. J Neurosci 26, 5117-5130.
    • (2006) J Neurosci , vol.26 , pp. 5117-5130
    • Akerman, C.J.1    Cline, H.T.2
  • 3
    • 33747063840 scopus 로고    scopus 로고
    • Retraction of synapses and dendritic spines induced by off-target effects of RNA interference
    • Alvarez VA, Ridenour DA & Sabatini BL (2006). Retraction of synapses and dendritic spines induced by off-target effects of RNA interference. J Neurosci 26, 7820-7825.
    • (2006) J Neurosci , vol.26 , pp. 7820-7825
    • Alvarez, V.A.1    Ridenour, D.A.2    Sabatini, B.L.3
  • 5
    • 35748954370 scopus 로고    scopus 로고
    • GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations
    • Ben-Ari Y, Gaiarsa JL, Tyzio R & Khazipov R (2007). GABA: a pioneer transmitter that excites immature neurons and generates primitive oscillations. Physiol Rev 87, 1215-1284.
    • (2007) Physiol Rev , vol.87 , pp. 1215-1284
    • Ben-Ari, Y.1    Gaiarsa, J.L.2    Tyzio, R.3    Khazipov, R.4
  • 6
    • 62549109964 scopus 로고    scopus 로고
    • Cation-chloride cotransporters and neuronal function
    • Blaesse P, Airaksinen MS, Rivera C & Kaila K (2009). Cation-chloride cotransporters and neuronal function. Neuron 61, 820-838.
    • (2009) Neuron , vol.61 , pp. 820-838
    • Blaesse, P.1    Airaksinen, M.S.2    Rivera, C.3    Kaila, K.4
  • 8
    • 0036179365 scopus 로고    scopus 로고
    • Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition
    • Boland A, Gerardy J, Mossay D, Delapierre D & Seutin V (2002). Pirlindole and dehydropirlindole protect rat cultured neuronal cells against oxidative stress-induced cell death through a mechanism unrelated to MAO-A inhibition. Br J Pharmacol 135, 713-720.
    • (2002) Br J Pharmacol , vol.135 , pp. 713-720
    • Boland, A.1    Gerardy, J.2    Mossay, D.3    Delapierre, D.4    Seutin, V.5
  • 9
    • 64149128876 scopus 로고    scopus 로고
    • KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner
    • Bortone D & Polleux F (2009). KCC2 expression promotes the termination of cortical interneuron migration in a voltage-sensitive calcium-dependent manner. Neuron 62, 53-71.
    • (2009) Neuron , vol.62 , pp. 53-71
    • Bortone, D.1    Polleux, F.2
  • 11
    • 0037134020 scopus 로고    scopus 로고
    • A system for stable expression of short interfering RNAs in mammalian cells
    • Brummelkamp TR, Bernards R & Agami R (2002). A system for stable expression of short interfering RNAs in mammalian cells. Science 296, 550-553.
    • (2002) Science , vol.296 , pp. 550-553
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 13
    • 34248383638 scopus 로고    scopus 로고
    • Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo
    • Cancedda L, Fiumelli H, Chen K & Poo MM (2007). Excitatory GABA action is essential for morphological maturation of cortical neurons in vivo. J Neurosci 27, 5224-5235.
    • (2007) J Neurosci , vol.27 , pp. 5224-5235
    • Cancedda, L.1    Fiumelli, H.2    Chen, K.3    Poo, M.M.4
  • 14
    • 23744504648 scopus 로고    scopus 로고
    • Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses
    • Chudotvorova I, Ivanov A, Rama S, Hubner CA, Pellegrino C, Ben Ari Y & Medina I (2005). Early expression of KCC2 in rat hippocampal cultures augments expression of functional GABA synapses. J Physiol 566, 671-679.
    • (2005) J Physiol , vol.566 , pp. 671-679
    • Chudotvorova, I.1    Ivanov, A.2    Rama, S.3    Hubner, C.A.4    Pellegrino, C.5    Ben Ari, Y.6    Medina, I.7
  • 15
    • 0034096243 scopus 로고    scopus 로고
    • Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes
    • Dokka S, Toledo D, Shi X, Castranova V & Rojanasakul Y (2000). Oxygen radical-mediated pulmonary toxicity induced by some cationic liposomes. Pharm Res 17, 521-525.
    • (2000) Pharm Res , vol.17 , pp. 521-525
    • Dokka, S.1    Toledo, D.2    Shi, X.3    Castranova, V.4    Rojanasakul, Y.5
  • 16
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE & Mello CC (1998). Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391, 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5    Mello, C.C.6
  • 18
    • 0035907025 scopus 로고    scopus 로고
    • GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition
    • Ganguly K, Schinder AF, Wong ST & Poo M (2001). GABA itself promotes the developmental switch of neuronal GABAergic responses from excitation to inhibition. Cell 105, 521-532.
    • (2001) Cell , vol.105 , pp. 521-532
    • Ganguly, K.1    Schinder, A.F.2    Wong, S.T.3    Poo, M.4
  • 19
    • 77956917231 scopus 로고    scopus 로고
    • Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
    • Hardingham GE & Bading H (2010). Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 11, 682-696.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 682-696
    • Hardingham, G.E.1    Bading, H.2
  • 20
    • 0036241207 scopus 로고    scopus 로고
    • Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
    • Hardingham GE, Fukunaga Y & Bading H (2002). Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 5, 405-414.
    • (2002) Nat Neurosci , vol.5 , pp. 405-414
    • Hardingham, G.E.1    Fukunaga, Y.2    Bading, H.3
  • 21
    • 77953769162 scopus 로고    scopus 로고
    • Premature expression of KCC2 in embryonic mice perturbs neural development by an ion transport-independent mechanism
    • Horn Z, Ringstedt T, Blaesse P, Kaila K & Herlenius E (2010). Premature expression of KCC2 in embryonic mice perturbs neural development by an ion transport-independent mechanism. Eur J Neurosci 31, 2142-2155.
    • (2010) Eur J Neurosci , vol.31 , pp. 2142-2155
    • Horn, Z.1    Ringstedt, T.2    Blaesse, P.3    Kaila, K.4    Herlenius, E.5
  • 22
    • 0034990498 scopus 로고    scopus 로고
    • Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition
    • Hubner CA, Stein V, Hermans-Borgmeyer I, Meyer T, Ballanyi K & Jentsch TJ (2001). Disruption of KCC2 reveals an essential role of K-Cl cotransport already in early synaptic inhibition. Neuron 30, 515-524.
    • (2001) Neuron , vol.30 , pp. 515-524
    • Hubner, C.A.1    Stein, V.2    Hermans-Borgmeyer, I.3    Meyer, T.4    Ballanyi, K.5    Jentsch, T.J.6
  • 23
    • 0027310916 scopus 로고
    • On neuronal health
    • Isacson O (1993). On neuronal health. Trends Neurosci 16, 306-308.
    • (1993) Trends Neurosci , vol.16 , pp. 306-308
    • Isacson, O.1
  • 24
    • 33645837486 scopus 로고    scopus 로고
    • Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the ERK activity in cultured rat hippocampal neurons
    • Ivanov A, Pellegrino C, Rama S, Dumalska I, Salyha Y, Ben Ari Y & Medina I (2006). Opposing role of synaptic and extrasynaptic NMDA receptors in regulation of the ERK activity in cultured rat hippocampal neurons. J Physiol 572, 789-798.
    • (2006) J Physiol , vol.572 , pp. 789-798
    • Ivanov, A.1    Pellegrino, C.2    Rama, S.3    Dumalska, I.4    Salyha, Y.5    Ben Ari, Y.6    Medina, I.7
  • 25
    • 77649152649 scopus 로고    scopus 로고
    • Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia
    • Jaenisch N, Witte OW & Frahm C (2010). Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia. Stroke 41, e151-e159.
    • (2010) Stroke , vol.41
    • Jaenisch, N.1    Witte, O.W.2    Frahm, C.3
  • 26
    • 15544364485 scopus 로고    scopus 로고
    • - extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex
    • - extrusion in layer V pyramidal neurons of chronically injured epileptogenic neocortex. J Neurophysiol 93, 2117-2126.
    • (2005) J Neurophysiol , vol.93 , pp. 2117-2126
    • Jin, X.1    Huguenard, J.R.2    Prince, D.A.3
  • 27
    • 2342529847 scopus 로고    scopus 로고
    • Electroporation-mediated gene transfer system applied to cultured CNS neurons
    • Kawabata I, Umeda T, Yamamoto K & Okabe S (2004). Electroporation-mediated gene transfer system applied to cultured CNS neurons. Neuroreport 15, 971-975.
    • (2004) Neuroreport , vol.15 , pp. 971-975
    • Kawabata, I.1    Umeda, T.2    Yamamoto, K.3    Okabe, S.4
  • 28
    • 77956600434 scopus 로고    scopus 로고
    • A single seizure episode leads to rapid functional activation of KCC2 in the neonatal rat hippocampus
    • Khirug S, Ahmad F, Puskarjov M, Afzalov R, Kaila K & Blaesse P (2010). A single seizure episode leads to rapid functional activation of KCC2 in the neonatal rat hippocampus. J Neurosci 30, 12028-12035.
    • (2010) J Neurosci , vol.30 , pp. 12028-12035
    • Khirug, S.1    Ahmad, F.2    Puskarjov, M.3    Afzalov, R.4    Kaila, K.5    Blaesse, P.6
  • 29
    • 16244388582 scopus 로고    scopus 로고
    • Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices
    • Khirug S, Huttu K, Ludwig A, Smirnov S, Voipio J, Rivera C, Kaila K & Khiroug L (2005). Distinct properties of functional KCC2 expression in immature mouse hippocampal neurons in culture and in acute slices. Eur J Neurosci 21, 899-904.
    • (2005) Eur J Neurosci , vol.21 , pp. 899-904
    • Khirug, S.1    Huttu, K.2    Ludwig, A.3    Smirnov, S.4    Voipio, J.5    Rivera, C.6    Kaila, K.7    Khiroug, L.8
  • 30
    • 44249116184 scopus 로고    scopus 로고
    • Dependence of reactive oxygen species and FLICE inhibitory protein on lipofectamine-induced apoptosis in human lung epithelial cells
    • Kongkaneramit L, Sarisuta N, Azad N, Lu Y, Iyer AK, Wang L & Rojanasakul Y (2008). Dependence of reactive oxygen species and FLICE inhibitory protein on lipofectamine-induced apoptosis in human lung epithelial cells. J Pharmacol Exp Ther 325, 969-977.
    • (2008) J Pharmacol Exp Ther , vol.325 , pp. 969-977
    • Kongkaneramit, L.1    Sarisuta, N.2    Azad, N.3    Lu, Y.4    Iyer, A.K.5    Wang, L.6    Rojanasakul, Y.7
  • 31
    • 0028937180 scopus 로고
    • Perforated-patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration
    • Kyrozis A & Reichling DB (1995). Perforated-patch recording with gramicidin avoids artifactual changes in intracellular chloride concentration. J Neurosci Methods 57, 27-35.
    • (1995) J Neurosci Methods , vol.57 , pp. 27-35
    • Kyrozis, A.1    Reichling, D.B.2
  • 32
    • 77955769549 scopus 로고    scopus 로고
    • Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2
    • Lee HH, Jurd R & Moss SJ (2010). Tyrosine phosphorylation regulates the membrane trafficking of the potassium chloride co-transporter KCC2. Mol Cell Neurosci 45, 173-179.
    • (2010) Mol Cell Neurosci , vol.45 , pp. 173-179
    • Lee, H.H.1    Jurd, R.2    Moss, S.J.3
  • 35
    • 0347419242 scopus 로고    scopus 로고
    • Developmental up-regulation of KCC2 in the absence of GABAergic and glutamatergic transmission
    • Ludwig A, Li H, Saarma M, Kaila K & Rivera C (2003). Developmental up-regulation of KCC2 in the absence of GABAergic and glutamatergic transmission. Eur J Neurosci 18, 3199-3206.
    • (2003) Eur J Neurosci , vol.18 , pp. 3199-3206
    • Ludwig, A.1    Li, H.2    Saarma, M.3    Kaila, K.4    Rivera, C.5
  • 37
    • 35148875095 scopus 로고    scopus 로고
    • Extrasynaptic NMDA receptors reshape gene ranks
    • Medina I (2007). Extrasynaptic NMDA receptors reshape gene ranks. Sci STKE 2007, e23.
    • (2007) Sci STKE , vol.2007
    • Medina, I.1
  • 38
    • 0033038527 scopus 로고    scopus 로고
    • i and the toxic actions of the HIV coat protein GP120
    • i and the toxic actions of the HIV coat protein GP120. Eur J Neurosci 11, 1167-1178.
    • (1999) Eur J Neurosci , vol.11 , pp. 1167-1178
    • Medina, I.1    Ghose, S.2    Ben Ari, Y.3
  • 40
    • 66349131378 scopus 로고    scopus 로고
    • Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus
    • Nardou R, Ben-Ari Y & Khalilov I (2009). Bumetanide, an NKCC1 antagonist, does not prevent formation of epileptogenic focus but blocks epileptic focus seizures in immature rat hippocampus. J Neurophysiol 101, 2878-2888.
    • (2009) J Neurophysiol , vol.101 , pp. 2878-2888
    • Nardou, R.1    Ben-Ari, Y.2    Khalilov, I.3
  • 41
    • 0037089589 scopus 로고    scopus 로고
    • Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
    • Paddison PJ, Caudy AA, Bernstein E, Hannon GJ & Conklin DS (2002). Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells. Genes Dev 16, 948-958.
    • (2002) Genes Dev , vol.16 , pp. 948-958
    • Paddison, P.J.1    Caudy, A.A.2    Bernstein, E.3    Hannon, G.J.4    Conklin, D.S.5
  • 43
    • 46549087720 scopus 로고    scopus 로고
    • Relationship between neuronal vulnerability and potassium-chloride cotransporter 2 immunoreactivity in hippocampus following transient forebrain ischemia
    • Papp E, Rivera C, Kaila K & Freund TF (2008). Relationship between neuronal vulnerability and potassium-chloride cotransporter 2 immunoreactivity in hippocampus following transient forebrain ischemia. Neuroscience 154, 677-689.
    • (2008) Neuroscience , vol.154 , pp. 677-689
    • Papp, E.1    Rivera, C.2    Kaila, K.3    Freund, T.F.4
  • 45
    • 2342489435 scopus 로고    scopus 로고
    • Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus
    • Pond BB, Galeffi F, Ahrens R & Schwartz-Bloom RD (2004). Chloride transport inhibitors influence recovery from oxygen-glucose deprivation-induced cellular injury in adult hippocampus. Neuropharmacology 47, 253-262.
    • (2004) Neuropharmacology , vol.47 , pp. 253-262
    • Pond, B.B.1    Galeffi, F.2    Ahrens, R.3    Schwartz-Bloom, R.D.4
  • 46
    • 15744368753 scopus 로고    scopus 로고
    • Trolox and 17β-estradiol protect against amyloid β-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway
    • Quintanilla RA, Munoz FJ, Metcalfe MJ, Hitschfeld M, Olivares G, Godoy JA & Inestrosa NC (2005). Trolox and 17β-estradiol protect against amyloid β-peptide neurotoxicity by a mechanism that involves modulation of the Wnt signaling pathway. J Biol Chem 280, 11615-11625.
    • (2005) J Biol Chem , vol.280 , pp. 11615-11625
    • Quintanilla, R.A.1    Munoz, F.J.2    Metcalfe, M.J.3    Hitschfeld, M.4    Olivares, G.5    Godoy, J.A.6    Inestrosa, N.C.7
  • 47
    • 39549097528 scopus 로고    scopus 로고
    • Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development
    • Reynolds A, Brustein E, Liao M, Mercado A, Babilonia E, Mount DB & Drapeau P (2008). Neurogenic role of the depolarizing chloride gradient revealed by global overexpression of KCC2 from the onset of development. J Neurosci 28, 1588-1597.
    • (2008) J Neurosci , vol.28 , pp. 1588-1597
    • Reynolds, A.1    Brustein, E.2    Liao, M.3    Mercado, A.4    Babilonia, E.5    Mount, D.B.6    Drapeau, P.7
  • 48
    • 0027965171 scopus 로고
    • Gramicidin perforated patch-clamp technique reveals glycine-gated outward chloride current in dissociated nucleus solitarii neurons of the rat
    • Rhee JS, Ebihara S & Akaike N (1994). Gramicidin perforated patch-clamp technique reveals glycine-gated outward chloride current in dissociated nucleus solitarii neurons of the rat. J Neurophysiol 72, 1103-1108.
    • (1994) J Neurophysiol , vol.72 , pp. 1103-1108
    • Rhee, J.S.1    Ebihara, S.2    Akaike, N.3
  • 52
    • 0021880922 scopus 로고
    • The neurotoxicity of excitatory amino acids is produced by passive chloride influx
    • Rothman SM (1985). The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J Neurosci 5, 1483-1489.
    • (1985) J Neurosci , vol.5 , pp. 1483-1489
    • Rothman, S.M.1
  • 53
    • 0034277056 scopus 로고    scopus 로고
    • Volume-sensitive KCI cotransport associated with human cervical carcinogenesis
    • Shen MR, Chou CY & Ellory JC (2000). Volume-sensitive KCI cotransport associated with human cervical carcinogenesis. Pflugers Arch 440, 751-760.
    • (2000) Pflugers Arch , vol.440 , pp. 751-760
    • Shen, M.R.1    Chou, C.Y.2    Ellory, J.C.3
  • 54
    • 66449102444 scopus 로고    scopus 로고
    • Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2
    • Soriano FX, Papadia S, Bell KF & Hardingham GE (2009). Role of histone acetylation in the activity-dependent regulation of sulfiredoxin and sestrin 2. Epigenetics 4, 152-158.
    • (2009) Epigenetics , vol.4 , pp. 152-158
    • Soriano, F.X.1    Papadia, S.2    Bell, K.F.3    Hardingham, G.E.4
  • 56
    • 0025805120 scopus 로고
    • A simple method for organotypic cultures of nervous tissue
    • Stoppini L, Buchs PA & Muller D (1991). A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 37, 173-182.
    • (1991) J Neurosci Methods , vol.37 , pp. 173-182
    • Stoppini, L.1    Buchs, P.A.2    Muller, D.3
  • 57
    • 0033368879 scopus 로고    scopus 로고
    • - cotransport in the regulatory volume decrease of newborn rat cardiomyocytes
    • - cotransport in the regulatory volume decrease of newborn rat cardiomyocytes. Pflugers Arch 439, 56-66.
    • (1999) Pflugers Arch , vol.439 , pp. 56-66
    • Taouil, K.1    Hannaert, P.2
  • 60
    • 0242425689 scopus 로고    scopus 로고
    • Membrane potential of CA3 hippocampal pyramidal cells during postnatal development
    • Tyzio R, Ivanov A, Bernard C, Holmes GL, Ben Ari Y & Khazipov R (2003). Membrane potential of CA3 hippocampal pyramidal cells during postnatal development. J Neurophysiol 90, 2964-2972.
    • (2003) J Neurophysiol , vol.90 , pp. 2964-2972
    • Tyzio, R.1    Ivanov, A.2    Bernard, C.3    Holmes, G.L.4    Ben Ari, Y.5    Khazipov, R.6
  • 63
    • 0035865259 scopus 로고    scopus 로고
    • Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture
    • Vergun O, Sobolevsky AI, Yelshansky MV, Keelan J, Khodorov BI & Duchen MR (2001). Exploration of the role of reactive oxygen species in glutamate neurotoxicity in rat hippocampal neurones in culture. J Physiol 531, 147-163.
    • (2001) J Physiol , vol.531 , pp. 147-163
    • Vergun, O.1    Sobolevsky, A.I.2    Yelshansky, M.V.3    Keelan, J.4    Khodorov, B.I.5    Duchen, M.R.6
  • 65
    • 77957688441 scopus 로고    scopus 로고
    • Genetically encoded Cl-Sensor as a tool for monitoring of Cl-dependent processes in small neuronal compartments
    • Waseem T, Mukhtarov M, Buldakova S, Medina I & Bregestovski P (2010). Genetically encoded Cl-Sensor as a tool for monitoring of Cl-dependent processes in small neuronal compartments. J Neurosci Methods 193, 14-23.
    • (2010) J Neurosci Methods , vol.193 , pp. 14-23
    • Waseem, T.1    Mukhtarov, M.2    Buldakova, S.3    Medina, I.4    Bregestovski, P.5
  • 67
    • 0037197914 scopus 로고    scopus 로고
    • RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells
    • Yu JY, DeRuiter SL & Turner DL (2002). RNA interference by expression of short-interfering RNAs and hairpin RNAs in mammalian cells. Proc Natl Acad Sci U S A 99, 6047-6052.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 6047-6052
    • Yu, J.Y.1    DeRuiter, S.L.2    Turner, D.L.3
  • 68
    • 14144253198 scopus 로고    scopus 로고
    • Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride
    • Zhu L, Lovinger D & Delpire E (2005). Cortical neurons lacking KCC2 expression show impaired regulation of intracellular chloride. J Neurophysiol 93, 1557-1568.
    • (2005) J Neurophysiol , vol.93 , pp. 1557-1568
    • Zhu, L.1    Lovinger, D.2    Delpire, E.3
  • 69
    • 42749090883 scopus 로고    scopus 로고
    • NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus
    • Zhu L, Polley N, Mathews GC & Delpire E (2008). NKCC1 and KCC2 prevent hyperexcitability in the mouse hippocampus. Epilepsy Res 79, 201-212.
    • (2008) Epilepsy Res , vol.79 , pp. 201-212
    • Zhu, L.1    Polley, N.2    Mathews, G.C.3    Delpire, E.4
  • 70


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