A novel agonistic anti-human death receptor 5 monoclonal antibody with tumoricidal activity induces caspase- and mitochondrial-dependent apoptosis in human leukemia jurkat cells

Cancer Biotherapy and Radiopharmaceuticals

Volumn 26, Issue 2, 2011, Pages 143-152

  Du, Yao Wu ^a   Chen, Ju Gao ^b   Bai, Hui Ling ^a   Huang, Hong Ying ^a   Wang, Jing ^a   Li, Shu Lian ^a   Liu, Guang Chao ^a,b   Jiang, Qi ^a   Chai, Jing ^a   Zhao, Yue Ping ^a   Ma, Yuan Fang ^a  

^a HENAN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

apoptosis; death receptor 5; Jurkat cells; monoclonal antibody; TRAIL

Indexed keywords

CASPASE; DEATH RECEPTOR 5; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, MONOCLONAL; APOPTOSIS; CASPASES; CYTOTOXICITY, IMMUNOLOGIC; ENZYME INDUCTION; HUMANS; JURKAT CELLS; LEUKEMIA; MITOCHONDRIA; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 79955903076     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2010.0827     Document Type: Article

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