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Volumn 7, Issue 2, 2011, Pages 123-131

Urate transport: Regulators of serum urate levels in humans

Author keywords

Benzbromarone; Hyperuricemia; Hypouricemia; Organic anions; Uric acid

Indexed keywords

4 AMINOHIPPURIC ACID; BREAST CANCER RESISTANCE PROTEIN; CARRIER PROTEIN; ECALECTIN; MULTIDRUG RESISTANCE PROTEIN 4; OCHRATOXIN; ORGANIC ANION TRANSPORTER 1; ORGANIC ANION TRANSPORTER 10; ORGANIC ANION TRANSPORTER 2; ORGANIC ANION TRANSPORTER 3; ORGANIC ANION TRANSPORTER 4; PDZ DOMAIN CONTAINING 1 PROTEIN; PENICILLIN G; PROTEIN SLC2A9; PROTEIN SMCT1; PROTEIN SMCT2; SALICYLIC ACID; SODIUM PHOSPHATE COTRANSPORTER 1; SODIUM PHOSPHATE COTRANSPORTER 4; UNCLASSIFIED DRUG; URATE; URATE TRANSPORTER 1; URIC ACID;

EID: 79955899714     PISSN: 15733971     EISSN: 18756360     Source Type: Journal    
DOI: 10.2174/157339711795305059     Document Type: Article
Times cited : (12)

References (54)
  • 1
    • 0033422249 scopus 로고    scopus 로고
    • Renal transport of urate in humans
    • Roch-Ramel F, Guisan B. Renal transport of urate in humans. News Physiol Sci 1999; 14: 80-4.
    • (1999) News Physiol Sci , vol.14 , pp. 80-84
    • Roch-Ramel, F.1    Guisan, B.2
  • 2
    • 0037161834 scopus 로고    scopus 로고
    • Molecular identification of a renal urate anion exchanger that regulates blood urate levels
    • Enomoto A, Kimura H, Chairoungdua A, et al. Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 2002; 417: 447-52.
    • (2002) Nature , vol.417 , pp. 447-452
    • Enomoto, A.1    Kimura, H.2    Chairoungdua, A.3
  • 3
    • 33846837206 scopus 로고    scopus 로고
    • New insights into renal transport of urate
    • Anzai N, Kanai Y, Endou H. New insights into renal transport of urate. Curr Opin Rheumatol 2007; 19: 151-7.
    • (2007) Curr Opin Rheumatol , vol.19 , pp. 151-157
    • Anzai, N.1    Kanai, Y.2    Endou, H.3
  • 4
    • 33747616258 scopus 로고    scopus 로고
    • Organic anion transporter family: Current knowledge
    • Anzai N, Kanai Y, Endou H. Organic anion transporter family: current knowledge. J Pharmacol Sci 2006; 100: 411-26.
    • (2006) J Pharmacol Sci , vol.100 , pp. 411-426
    • Anzai, N.1    Kanai, Y.2    Endou, H.3
  • 5
    • 0032919287 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney
    • Hosoyamada M, Sekine T, Kanai Y, Endou H. Molecular cloning and functional expression of a multispecific organic anion transporter from human kidney. Am J Physiol 1999; 276: F122-8.
    • (1999) Am J Physiol , vol.276
    • Hosoyamada, M.1    Sekine, T.2    Kanai, Y.3    Endou, H.4
  • 6
    • 0037213731 scopus 로고    scopus 로고
    • Urate transport via human PAH transporter hOAT1 and its gene structure
    • Ichida K, Hosoyamada M, Kimura H, et al. Urate transport via human PAH transporter hOAT1 and its gene structure. Kidney Int 2003; 63: 143-55.
    • (2003) Kidney Int , vol.63 , pp. 143-155
    • Ichida, K.1    Hosoyamada, M.2    Kimura, H.3
  • 7
    • 43049121374 scopus 로고    scopus 로고
    • Multiple organic anion transporters contribute to net renal excretion of uric acid
    • Eraly SA, Vallon V, Rieg T, et al. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics 2008; 33: 180-92.
    • (2008) Physiol Genomics , vol.33 , pp. 180-192
    • Eraly, S.A.1    Vallon, V.2    Rieg, T.3
  • 8
    • 17144449057 scopus 로고    scopus 로고
    • Identification of multispecific organic anion transporter 2 expressed predominantly in the liver
    • Sekine T, Cha SH, Tsuda M, et al. Identification of multispecific organic anion transporter 2 expressed predominantly in the liver. FEBS Lett 1998; 429: 179-82.
    • (1998) FEBS Lett , vol.429 , pp. 179-182
    • Sekine, T.1    Cha, S.H.2    Tsuda, M.3
  • 9
    • 77649212118 scopus 로고    scopus 로고
    • Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human
    • Sato M, Mamada H, Anzai N, Shirasaka Y, Nakanishi T, Tamai I. Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human. Biol Pharm Bull 2010; 33(3): 498-503.
    • (2010) Biol Pharm Bull , vol.33 , Issue.3 , pp. 498-503
    • Sato, M.1    Mamada, H.2    Anzai, N.3    Shirasaka, Y.4    Nakanishi, T.5    Tamai, I.6
  • 10
    • 0036260663 scopus 로고    scopus 로고
    • Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors
    • Enomoto A, Takeda M, Shimoda M, et al. Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors. J Pharmacol Exp Ther 2002; 301: 797-802.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 797-802
    • Enomoto, A.1    Takeda, M.2    Shimoda, M.3
  • 11
    • 0035039326 scopus 로고    scopus 로고
    • Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney
    • Cha SH, Sekine T, Fukushima JI, et al. Identification and characterization of human organic anion transporter 3 expressing predominantly in the kidney. Mol Pharmacol 2001; 59: 1277-86.
    • (2001) Mol Pharmacol , vol.59 , pp. 1277-1286
    • Cha, S.H.1    Sekine, T.2    Fukushima, J.I.3
  • 12
    • 23844514428 scopus 로고    scopus 로고
    • Renal urate handling: Clinical relevance of recent advances
    • Anzai N, Enomoto A, Endou H. Renal urate handling: clinical relevance of recent advances. Curr Rheumatol Rep 2005; 7: 227-34.
    • (2005) Curr Rheumatol Rep , vol.7 , pp. 227-234
    • Anzai, N.1    Enomoto, A.2    Endou, H.3
  • 13
    • 0242290366 scopus 로고    scopus 로고
    • Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux
    • Bakhiya A, Bahn A, Burckhardt G, Wolff N. Human organic anion transporter 3 (hOAT3) can operate as an exchanger and mediate secretory urate flux. Cell Physiol Biochem 2003; 13: 249-56.
    • (2003) Cell Physiol Biochem , vol.13 , pp. 249-256
    • Bakhiya, A.1    Bahn, A.2    Burckhardt, G.3    Wolff, N.4
  • 14
    • 1842732504 scopus 로고    scopus 로고
    • Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules
    • Ekaratanawong S, Anzai N, Jutabha P, et al. Human organic anion transporter 4 is a renal apical organic anion/dicarboxylate exchanger in the proximal tubules. J Pharmacol Sci 2004; 94: 297-304.
    • (2004) J Pharmacol Sci , vol.94 , pp. 297-304
    • Ekaratanawong, S.1    Anzai, N.2    Jutabha, P.3
  • 15
    • 33846692496 scopus 로고    scopus 로고
    • Human renal organic anion transporter 4 operates as an asymmetric urate transporter
    • Hagos Y, Stein D, Ugele B, et al. Human renal organic anion transporter 4 operates as an asymmetric urate transporter. J Am Soc Nephrol 2007; 18: 430-9.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 430-439
    • Hagos, Y.1    Stein, D.2    Ugele, B.3
  • 16
    • 40549090278 scopus 로고    scopus 로고
    • Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers
    • Sato M, Iwanaga T, Mamada H, et al. Involvement of uric acid transporters in alteration of serum uric acid level by angiotensin II receptor blockers. Pharm Res 2008; 25: 639-46.
    • (2008) Pharm Res , vol.25 , pp. 639-646
    • Sato, M.1    Iwanaga, T.2    Mamada, H.3
  • 17
    • 67651056502 scopus 로고    scopus 로고
    • Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
    • Kolz M, Johnson T, Sanna S, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet 2009; 5: e1000504.
    • (2009) PLoS Genet , vol.5
    • Kolz, M.1    Johnson, T.2    Sanna, S.3
  • 18
    • 47749112096 scopus 로고    scopus 로고
    • Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)
    • Bahn A, Hagos Y, Reuter S, et al. Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13). J Biol Chem 2008; 283: 16332-41.
    • (2008) J Biol Chem , vol.283 , pp. 16332-16341
    • Bahn, A.1    Hagos, Y.2    Reuter, S.3
  • 19
    • 0346734163 scopus 로고    scopus 로고
    • Clinical and molecular analysis of patients with renal hypouricemia in Japaninfluence of URAT1 gene on urinary urate excretion
    • Ichida, K, Hosoyamada M, Hisatome I, et al. Clinical and molecular analysis of patients with renal hypouricemia in Japaninfluence of URAT1 gene on urinary urate excretion. J Am Soc Nephrol 2004; 15: 164-73.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 164-173
    • Ichida, K.1    Hosoyamada, M.2    Hisatome, I.3
  • 20
    • 3543124167 scopus 로고    scopus 로고
    • The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules
    • Imaoka T, Kusuhara H, Adachi-Akahane S, et al. The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules. J Am Soc Nephrol 2004; 15: 2012-22.
    • (2004) J Am Soc Nephrol , vol.15 , pp. 2012-2022
    • Imaoka, T.1    Kusuhara, H.2    Adachi-Akahane, S.3
  • 21
    • 28144462450 scopus 로고    scopus 로고
    • Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone
    • Iwanaga T, Kobayashi D, Hirayama M, Maeda T, Tamai I. Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone. Drug Metab Dispos 2005; 33: 1791-5.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1791-1795
    • Iwanaga, T.1    Kobayashi, D.2    Hirayama, M.3    Maeda, T.4    Tamai, I.5
  • 23
    • 9244264985 scopus 로고    scopus 로고
    • Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter
    • Li T, Walsh JR, Ghishan FK, Bai L. Molecular cloning and characterization of a human urate transporter (hURAT1) gene promoter. Biochim Biophys Acta 2004; 1681: 53-58.
    • (2004) Biochim Biophys Acta , vol.1681 , pp. 53-58
    • Li, T.1    Walsh, J.R.2    Ghishan, F.K.3    Bai, L.4
  • 24
    • 36348965458 scopus 로고    scopus 로고
    • Regulation of tissuespecific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation
    • Kikuchi R, Kusuhara H, Hattori N, et al. Regulation of tissuespecific expression of the human and mouse urate transporter 1 gene by hepatocyte nuclear factor 1 alpha/beta and DNA methylation. Mol Pharmacol 2007; 72: 1619-25.
    • (2007) Mol Pharmacol , vol.72 , pp. 1619-1625
    • Kikuchi, R.1    Kusuhara, H.2    Hattori, N.3
  • 25
    • 0034595094 scopus 로고    scopus 로고
    • P-aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1
    • Uchino H, Tamai I, Yamashita K, et al. P-aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1. Biochem Biophys Res Commun 2000; 270(1): 254-9.
    • (2000) Biochem Biophys Res Commun , vol.270 , Issue.1 , pp. 254-259
    • Uchino, H.1    Tamai, I.2    Yamashita, K.3
  • 26
    • 0041344601 scopus 로고    scopus 로고
    • Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule
    • Jutabha P, Kanai Y, Hosoyamada H, et al. Identification of a novel voltage-driven organic anion transporter present at apical membrane of renal proximal tubule. J Biol Chem 2003; 278: 27930-8.
    • (2003) J Biol Chem , vol.278 , pp. 27930-27938
    • Jutabha, P.1    Kanai, Y.2    Hosoyamada, H.3
  • 27
    • 77951092761 scopus 로고    scopus 로고
    • Sodium-dependent phosphate cotransporter type 1 (NPT1) sequence polymorphisms in male patients with gout
    • Urano W, Taniguchi A, Anzai N, et al. Sodium-dependent phosphate cotransporter type 1 (NPT1) sequence polymorphisms in male patients with gout. Ann Rheum Dis 2010; 69: 1232-4.
    • (2010) Ann Rheum Dis , vol.69 , pp. 1232-1234
    • Urano, W.1    Taniguchi, A.2    Anzai, N.3
  • 28
    • 57049083981 scopus 로고    scopus 로고
    • Association of three genetic loci with uric acid concentration and risk of gout: A genome-wide association study
    • Dehghan A, Köttgen A, Yang Q, et al. Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study. Lancet 2008; 372: 1953-61.
    • (2008) Lancet , vol.372 , pp. 1953-1961
    • Dehghan, A.1    Köttgen, A.2    Yang, Q.3
  • 29
    • 78049387680 scopus 로고    scopus 로고
    • Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate
    • Jurabha P, Anzai N, Kitamura K, et al. Human sodium phosphate transporter 4 (hNPT4/SLC17A3) as a common renal secretory pathway for drugs and urate. J Biol Chem 2010; 285(45): 35123-32.
    • (2010) J Biol Chem , vol.285 , Issue.45 , pp. 35123-35132
    • Jurabha, P.1    Anzai, N.2    Kitamura, K.3
  • 30
    • 12144257103 scopus 로고    scopus 로고
    • Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites
    • van Aubel RA, Smeets PH, van den Heuvel JJ, et al. Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. Am J Physiol Renal Physiol 2005; 288: F327-33.
    • (2005) Am J Physiol Renal Physiol , vol.288
    • van Aubel, R.A.1    Smeets, P.H.2    van den Heuvel, J.J.3
  • 31
    • 56749156484 scopus 로고    scopus 로고
    • Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4
    • El-Sheikh AA, van den Heuvel JJ, Koenderink JB, et al. Effect of hypouricaemic and hyperuricaemic drugs on the renal urate efflux transporter, multidrug resistance protein 4. Br J Pharmacol 2008; 155: 1066-75.
    • (2008) Br J Pharmacol , vol.155 , pp. 1066-1075
    • El-Sheikh, A.A.1    van den Heuvel, J.J.2    Koenderink, J.B.3
  • 33
    • 37549068911 scopus 로고    scopus 로고
    • The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane
    • Huls M, Brown CD, Windass AS, et al. The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane. Kidney Int 2008; 73: 220-5.
    • (2008) Kidney Int , vol.73 , pp. 220-225
    • Huls, M.1    Brown, C.D.2    Windass, A.S.3
  • 35
    • 7244236578 scopus 로고    scopus 로고
    • Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate
    • Gopal E, Fei YJ, Sugawara M, et al. Expression of slc5a8 in kidney and its role in Na(+)-coupled transport of lactate. J Biol Chem 2004; 279: 44522-32.
    • (2004) J Biol Chem , vol.279 , pp. 44522-44532
    • Gopal, E.1    Fei, Y.J.2    Sugawara, M.3
  • 37
    • 35848971238 scopus 로고    scopus 로고
    • Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney
    • Gopal E, Umapathy NS, Martin PM, et al. Cloning and functional characterization of human SMCT2 (SLC5A12) and expression pattern of the transporter in kidney. Biochim Biophys Acta 2007; 1768: 2690-7.
    • (2007) Biochim Biophys Acta , vol.1768 , pp. 2690-2697
    • Gopal, E.1    Umapathy, N.S.2    Martin, P.M.3
  • 38
    • 37349008492 scopus 로고    scopus 로고
    • The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts
    • Li S, Sanna S, Maschio A, et al. The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. PLoS Genet 2007; 3: e194.
    • (2007) PLoS Genet , vol.3
    • Li, S.1    Sanna, S.2    Maschio, A.3
  • 39
    • 41449093735 scopus 로고    scopus 로고
    • SLC2A9 influences uric acid concentrations with pronounced sex-specific effects
    • Döring A, Gieger C, Mehta D, et al. SLC2A9 influences uric acid concentrations with pronounced sex-specific effects. Nat Genet 2008; 40: 430-6.
    • (2008) Nat Genet , vol.40 , pp. 430-436
    • Döring, A.1    Gieger, C.2    Mehta, D.3
  • 40
    • 41349103917 scopus 로고    scopus 로고
    • SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
    • Vitart V, Rudan I, Hayward C, et al. SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nat Genet 2008; 40: 437-42.
    • (2008) Nat Genet , vol.40 , pp. 437-442
    • Vitart, V.1    Rudan, I.2    Hayward, C.3
  • 41
    • 1942437498 scopus 로고    scopus 로고
    • Identification and characterization of human glucose transporter-like protein-9 (GLUT9): Alternative splicing alters trafficking
    • Augustin R, Carayannopoulos MO, Dowd LO, Phay JE, Moley JF, Moley KH. Identification and characterization of human glucose transporter-like protein-9 (GLUT9): alternative splicing alters trafficking. J Biol Chem 2004; 279: 16229-36.
    • (2004) J Biol Chem , vol.279 , pp. 16229-16236
    • Augustin, R.1    Carayannopoulos, M.O.2    Dowd, L.O.3    Phay, J.E.4    Moley, J.F.5    Moley, K.H.6
  • 42
    • 55249096942 scopus 로고    scopus 로고
    • Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans
    • Anzai N, Ichida K, Jutabha P, et al. Plasma urate level is directly regulated by a voltage-driven urate efflux transporter URATv1 (SLC2A9) in humans. J Biol Chem 2008; 283: 26834-8.
    • (2008) J Biol Chem , vol.283 , pp. 26834-26838
    • Anzai, N.1    Ichida, K.2    Jutabha, P.3
  • 43
    • 75149114710 scopus 로고    scopus 로고
    • Homozygous SLC2A9 mutations cause severe renal hypouricemia
    • Dinour D, Gray NK, Campbell S, et al. Homozygous SLC2A9 mutations cause severe renal hypouricemia. J Am Soc Nephrol 2010; 21: 64-72.
    • (2010) J Am Soc Nephrol , vol.21 , pp. 64-72
    • Dinour, D.1    Gray, N.K.2    Campbell, S.3
  • 45
    • 0035024743 scopus 로고    scopus 로고
    • Functional reconstitution, membrane targeting, genomic structure, and chromosomal localization of a human urate transporter
    • Lipkowitz MS, Leal-Pinto E, Rappoport JZ, et al. Functional reconstitution, membrane targeting, genomic structure, and chromosomal localization of a human urate transporter. J Clin Invest 2001; 107: 1103-15
    • (2001) J Clin Invest , vol.107 , pp. 1103-1115
    • Lipkowitz, M.S.1    Leal-Pinto, E.2    Rappoport, J.Z.3
  • 46
    • 33751084598 scopus 로고    scopus 로고
    • The emerging role of PDZ adapter proteins for regulation of intestinal ion transport
    • Lamprecht G, Seidler U. The emerging role of PDZ adapter proteins for regulation of intestinal ion transport. Am J Physiol Gastrointest Liver Physiol 2006; 291: G766-77.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.291
    • Lamprecht, G.1    Seidler, U.2
  • 47
    • 8544277306 scopus 로고    scopus 로고
    • The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus
    • Anzai N, Miyazaki H, Noshiro R, et al. The multivalent PDZ domain-containing protein PDZK1 regulates transport activity of renal urate-anion exchanger URAT1 via its C terminus. J Biol Chem 2004; 279: 45942-50.
    • (2004) J Biol Chem , vol.279 , pp. 45942-45950
    • Anzai, N.1    Miyazaki, H.2    Noshiro, R.3
  • 48
    • 10744227996 scopus 로고    scopus 로고
    • PDZK1: I. a major scaffolder in brush borders of proximal tubular cells
    • Gisler SM, Pribanic S, Bacic D, et al. PDZK1: I. a major scaffolder in brush borders of proximal tubular cells. Kidney Int 2003; 64: 1733-45.
    • (2003) Kidney Int , vol.64 , pp. 1733-1745
    • Gisler, S.M.1    Pribanic, S.2    Bacic, D.3
  • 49
    • 33748755827 scopus 로고    scopus 로고
    • C/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney
    • Thangaraju M, Ananth S, Martin PM, et al. c/ebpdelta Null mouse as a model for the double knock-out of slc5a8 and slc5a12 in kidney. J Biol Chem 2006; 281: 26769-73.
    • (2006) J Biol Chem , vol.281 , pp. 26769-26773
    • Thangaraju, M.1    Ananth, S.2    Martin, P.M.3
  • 50
    • 28044456979 scopus 로고    scopus 로고
    • Metabolic syndrome: Demographic features, etiology, and clinical management
    • Wyne KL. Metabolic syndrome: demographic features, etiology, and clinical management. Curr Atheroscler Rep 2005; 7: 381-8.
    • (2005) Curr Atheroscler Rep , vol.7 , pp. 381-388
    • Wyne, K.L.1
  • 51
    • 29244440864 scopus 로고    scopus 로고
    • Metabolic syndrome: Historical perspectives
    • Leslie BR. Metabolic syndrome: historical perspectives. Am J Med Sci 2005; 330: 264-8.
    • (2005) Am J Med Sci , vol.330 , pp. 264-268
    • Leslie, B.R.1
  • 52
    • 33645560926 scopus 로고    scopus 로고
    • A causal role for uric acid in fructose-induced metabolic syndrome
    • Nakagawa T, Hu H, Zharikov S, et al. A causal role for uric acid in fructose-induced metabolic syndrome. Am J Physiol Renal Physiol 2006; 290: F625-31.
    • (2006) Am J Physiol Renal Physiol , vol.290
    • Nakagawa, T.1    Hu, H.2    Zharikov, S.3
  • 53
    • 34848852618 scopus 로고    scopus 로고
    • Drug discovery for hyperuricemia
    • Anzai N, Endou H. Drug discovery for hyperuricemia. Expert Opin Drug Discov 2007; 2: 1251-61.
    • (2007) Expert Opin Drug Discov , vol.2 , pp. 1251-1261
    • Anzai, N.1    Endou, H.2
  • 54
    • 70349345913 scopus 로고    scopus 로고
    • Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy
    • Preitner F, Bonny O, Laverrière A, et al. Glut9 is a major regulator of urate homeostasis and its genetic inactivation induces hyperuricosuria and urate nephropathy. Proc Natl Acad Sci USA 2009; 106: 15501-6.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 15501-15506
    • Preitner, F.1    Bonny, O.2    Laverrière, A.3


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