Immunosuppressive but non-LasR-inducing analogues of the pseudomonas aeruginosa quorum-sensing molecule N-(3-Oxododecanoyl)-l-homoserine Lactone

Journal of Medicinal Chemistry

Volumn 54, Issue 9, 2011, Pages 3348-3359

  Jadhav, Gopal P ^a   Chhabra, Siri Ram ^a   Telford, Gary ^a   Hooi, Doreen S W ^a   Righetti, Karima ^a   Williams, Paul ^a   Kellam, Barrie ^a   Pritchard, David I ^a   Fischer, Peter M ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 (1 NONYLHYDRAZINYL) N (2 OXOTETRAHYDROFURAN 3 YL)ACETAMIDE; 2 (N OCTYLSULFAMOYL) N (2 OXOTETRAHYDROFURAN 3 YL)ACETAMIDE; 2 [BENZYLOXY(NONYL)AMINO] N (2 OXOTETRAHYDROFURAN 3 YL)ACETAMIDE; 2 [HYDROXYL(NONYL)AMINO] N (2 OXOTETRAHYDROFURAN 3 YL)ACETAMIDE; 3 OXO N (THIAZOL 2 YL)DODECANAMIDE; IMMUNOSUPPRESSIVE AGENT; N (2 OXOTETRAHYDROFURAN 3 YL) 2 (UNDECYLSULFINYL)ACETAMIDE; N (2 OXOTETRAHYDROFURAN 3 YL) 2 (UNDECYLSULFONYL)ACETAMIDE; N (3 OXODODECANOYL)HOMOSERINE LACTONE; N OCTYL 2 [N (2 OXOTETRAHYDROFURAN 3 YL)SULFAMOYL]ACETAMIDE; N1 (2 CARBAMOYLPHENYL) N3 OCTYLMALONAMIDE; N1 (2 HYDROXYPHENYL) N3 OCTYLMALONAMIDE; N1 (3 CARBAMOYLPHENYL) N3 OCTYLMALONAMIDE; N1 (5 CHLORO 2 HYDROXYPHENYL) N3 OCTYLMALONAMIDE; N1 [2 (DIMETHYLCARBAMOYL)PHENYL] N3 OCTYLMALONAMIDE; N1 CYCLOHEPTYL N3 OCTYLMALONAMIDE; N1 OCTYL N3 (PYRIDIN 2 YL)MALONAMIDE; SULFONAMIDE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR LASR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOLUMINESCENCE; CELL PROLIFERATION; CYTOTOXICITY; DRUG ACTIVITY; DRUG DESIGN; DRUG POTENCY; DRUG SYNTHESIS; LEUKOCYTE; MOUSE; NONHUMAN; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; STRUCTURE ACTIVITY RELATION;

4-BUTYROLACTONE; ANIMALS; AZA COMPOUNDS; BACTERIAL PROTEINS; CELL PROLIFERATION; HOMOSERINE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; JURKAT CELLS; LEUKOCYTES; LUMINESCENT MEASUREMENTS; MICE; PSEUDOMONAS AERUGINOSA; QUORUM SENSING; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-ACTIVATORS;

EID: 79955851420     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm2001019     Document Type: Article

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