메뉴 건너뛰기




Volumn 90, Issue 6, 2011, Pages 452-465

Exercise paradigms to study brain injury recovery in rodents

Author keywords

Animal Model; Brain; Exercise; Neurodegenerative Disease; Physical Activity; Plasticity

Indexed keywords

ANIMAL; ANIMAL EXPERIMENT; BRAIN INJURY; COMPARATIVE STUDY; CONVALESCENCE; DEGENERATIVE DISEASE; DISEASE MODEL; EXERCISE TEST; FEMALE; MALE; METABOLISM; METHODOLOGY; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZATION; RAT; REVIEW; RISK ASSESSMENT; RODENT; SPRAGUE DAWLEY RAT;

EID: 79955802036     PISSN: 08949115     EISSN: None     Source Type: Journal    
DOI: 10.1097/PHM.0b013e3182063a9c     Document Type: Review
Times cited : (49)

References (133)
  • 1
    • 0021798918 scopus 로고
    • Physical activity, exercise and physical fitness: Definitions and distinctions for health-related research
    • Caspersen CJ, Powell KE, Christenson GM: Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep 1985;100:126-31 (Pubitemid 15064369)
    • (1985) Public Health Reports , vol.100 , Issue.2 , pp. 126-131
    • Caspersen, C.J.1    Powell, K.E.2    Christenson, G.3
  • 2
    • 0025231633 scopus 로고
    • Influence of thyroid hormones and catecholamines on myosin of swim-exercised rats
    • Rupp H, Wahl R: Influence of thyroid hormones and catecholamines on myosin of swim-exercised rats. J Appl Physiol 1990;68:973-8 (Pubitemid 20136421)
    • (1990) Journal of Applied Physiology , vol.68 , Issue.3 , pp. 973-978
    • Rupp, H.1    Wahl, R.2
  • 3
    • 0025137869 scopus 로고
    • Oxygen consumption and distribution of blood flow in rats climbing a laddermill
    • Norton KI, Jones MT, Armstrong RB: Oxygen consumption and distribution of blood flow in rats climbing a laddermill. J Appl Physiol 1990;68:241-7 (Pubitemid 20075238)
    • (1990) Journal of Applied Physiology , vol.68 , Issue.1 , pp. 241-247
    • Norton, K.I.1    Jones, M.T.2    Armstrong, R.B.3
  • 4
    • 0023819272 scopus 로고
    • Skeletal muscle enlargement with weight-lifting exercise by rats
    • Wong TS, Booth FW: Skeletal muscle enlargement with weight-lifting exercise by rats. J Appl Physiol 1988;65:950-4
    • (1988) J Appl Physiol , vol.65 , pp. 950-954
    • Wong, T.S.1    Booth, F.W.2
  • 6
    • 0024478141 scopus 로고
    • Dissociation of changes in VO2, muscle QO2, and performance with training in rats
    • Lambert MI, Noakes TD: Dissociation of changes in VO2, muscle QO2, and performance with training in rats. J Appl Physiol 1989;66:1620-5
    • (1989) J Appl Physiol , vol.66 , pp. 1620-1625
    • Lambert, M.I.1    Noakes, T.D.2
  • 7
    • 0032126142 scopus 로고    scopus 로고
    • Voluntary wheel running: A review and novel interpretation
    • DOI 10.1006/anbe.1998.0836
    • Sherwin CM: Voluntary wheel running: a review and novel interpretation. Anim Behav 1998;56:11-27 (Pubitemid 28348956)
    • (1998) Animal Behaviour , vol.56 , Issue.1 , pp. 11-27
    • Sherwin, C.M.1
  • 8
    • 0014222265 scopus 로고
    • Behavior of captive white-footed mice
    • Kavanau JL: Behavior of captive white-footed mice. Science 1967;155:1623-39
    • (1967) Science , vol.155 , pp. 1623-1639
    • Kavanau, J.L.1
  • 9
    • 0024149606 scopus 로고
    • A microanalysis of wheel running in male and female rats
    • DOI 10.1016/0031-9384(88)90217-X
    • Eikelboom R, Mills R: A microanalysis of wheel running in male and female rats. Physiol Behav 1988;43:625-30 (Pubitemid 19207524)
    • (1988) Physiology and Behavior , vol.43 , Issue.5 , pp. 625-630
    • Eikelboom, R.1    Mills, R.2
  • 10
    • 30944435509 scopus 로고    scopus 로고
    • Effects of size, sex, and voluntary running speeds on costs of locomotion in lines of laboratory mice selectively bred for high wheel-running activity
    • DOI 10.1086/498187
    • Rezende EL, Kelly SA, Gomes FR, et al: Effects of size, sex, and voluntary running speeds on costs of locomotion in lines of laboratory mice selectively bred for high wheel running activity. Physiol Biochem Zool 2006;79:83-99 (Pubitemid 43112607)
    • (2006) Physiological and Biochemical Zoology , vol.79 , Issue.1 , pp. 83-99
    • Rezende, E.L.1    Kelly, S.A.2    Gomes, F.R.3    Chappell, M.A.4    Garland Jr., T.5
  • 11
    • 0035783908 scopus 로고    scopus 로고
    • Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus
    • DOI 10.1046/j.0953-816X.2001.01825.x
    • Berchtold NC, Kesslak JP, Pike CJ, et al: Estrogen and exercise interact to regulate brain-derived neurotrophic factor mRNA and protein expression in the hippocampus. Eur J Neurosci 2001;14: 1992-2002 (Pubitemid 35463686)
    • (2001) European Journal of Neuroscience , vol.14 , Issue.12 , pp. 1992-2002
    • Berchtold, N.C.1    Kesslak, J.P.2    Pike, C.J.3    Adlard, P.A.4    Cotman, C.W.5
  • 12
    • 30344448859 scopus 로고    scopus 로고
    • Influence of estrus cycle and ageing on activity patterns in two inbred mouse strains
    • DOI 10.1016/j.bbr.2005.09.001, PII S0166432805003773
    • Kopp C, Ressel V, Wigger E, et al: Influence of estrus cycle and ageing on activity patterns in two inbred mouse strains. Behav Brain Res 2006;167:165-74 (Pubitemid 43063152)
    • (2006) Behavioural Brain Research , vol.167 , Issue.1 , pp. 165-174
    • Kopp, C.1    Ressel, V.2    Wigger, E.3    Tobler, I.4
  • 13
    • 0024463691 scopus 로고
    • The effect of wheel running and the estrous cycle on energy expenditure in female rats
    • DOI 10.1016/0031-9384(89)90265-5
    • Anantharaman-Barr HG, Decombaz J: The effect of wheel running and the estrous cycle on energy expenditure in female rats. Physiol Behav 1989;46: 259-63 (Pubitemid 19244088)
    • (1989) Physiology and Behavior , vol.46 , Issue.2 , pp. 259-263
    • Anantharaman-Barr, H.G.1    Decombaz, J.2
  • 17
    • 0141919620 scopus 로고    scopus 로고
    • Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running
    • DOI 10.1037/0735-7044.117.5.1006
    • Rhodes JS, Van Praag H, Jeffrey S, et al: Exercise increases hippocampal neurogenesis to high levels but does not improve spatial learning in mice bred for increased voluntary wheel running. Behav Neurosci 2003;117:1006-16 (Pubitemid 37243783)
    • (2003) Behavioral Neuroscience , vol.117 , Issue.5 , pp. 1006-1016
    • Rhodes, J.S.1    Jeffrey, S.2    Girard, I.3    Mitchell, G.S.4    Van Praag, H.5    Garland Jr., T.6    Gage, F.H.7
  • 19
    • 0028094612 scopus 로고
    • Expression of creatine kinase M and B mRNAs in treadmill trained rat skeletal muscle
    • Apple FS, Billadello JJ: Expression of creatine kinase M and B mRNAs in treadmill trained rat skeletal muscle. Life Sci 1994;55:585-92
    • (1994) Life Sci , vol.55 , pp. 585-592
    • Apple, F.S.1    Billadello, J.J.2
  • 20
    • 0031591654 scopus 로고    scopus 로고
    • Treadmill running increases phosphatidylinostol 3-kinase activity in rat skeletal muscle
    • DOI 10.1006/bbrc.1997.7028
    • Zhou Q, Dohm GL: Treadmill running increases phosphatidylinositol 3-kinase activity in rat skeletal muscle. Biochem Biophys Res Commun 1997;236: 647-50 (Pubitemid 27384682)
    • (1997) Biochemical and Biophysical Research Communications , vol.236 , Issue.3 , pp. 647-650
    • Zhou, Q.1    Dohm, G.L.2
  • 21
  • 23
    • 0034971980 scopus 로고    scopus 로고
    • Intensitycontrolled treadmill running in rats: VO(2 max) and cardiac hypertrophy
    • Wisloff U, Helgerud J, Kemi OJ, et al: Intensitycontrolled treadmill running in rats: VO(2 max) and cardiac hypertrophy. Am J Physiol Heart Circ Physiol 2001;280:H1301-10
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Wisloff, U.1    Helgerud, J.2    Kemi, O.J.3
  • 26
    • 0000152483 scopus 로고
    • The effects of early experience on problemsolving at maturity
    • Hebb DO: The effects of early experience on problemsolving at maturity. Am Psychol 1947;2:306-7
    • (1947) Am Psychol , vol.2 , pp. 306-307
    • Hebb, D.O.1
  • 28
    • 0014541753 scopus 로고
    • Influences of environmental complexity and visual stimulation on development of occipital cortex in rat
    • Rosenzweig MR, Bennett EL, Diamond MC, et al: Influences of environmental complexity and visual stimulation on development of occipital cortex in rat. Brain Res 1969;14:427-45
    • (1969) Brain Res , vol.14 , pp. 427-445
    • Rosenzweig, M.R.1    Bennett, E.L.2    Diamond, M.C.3
  • 29
    • 0015381578 scopus 로고
    • Cerebral changes in rats exposed individually to an enriched environment
    • Rosenzweig MR, Bennett EL: Cerebral changes in rats exposed individually to an enriched environment. J Comp Physiol Psychol 1972;80:304-13
    • (1972) J Comp Physiol Psychol , vol.80 , pp. 304-313
    • Rosenzweig, M.R.1    Bennett, E.L.2
  • 30
    • 0037936789 scopus 로고    scopus 로고
    • Impact of aging on hippocampal function: Plasticity, network dynamics, and cognition
    • DOI 10.1016/S0301-0082(02)00126-0
    • Rosenzweig ES, Barnes CA: Impact of aging on hippocampal function: plasticity, network dynamics, and cognition. Prog Neurobiol 2003;69:143-79 (Pubitemid 36577321)
    • (2003) Progress in Neurobiology , vol.69 , Issue.3 , pp. 143-179
    • Rosenzweig, E.S.1    Barnes, C.A.2
  • 31
    • 0028072384 scopus 로고
    • Exercise physiology of wild and random-bred laboratory house mice and their reciprocal hybrids
    • Dohm MR, Richardson CS, Garland T: Exercise physiology of wild and random-bred laboratory house mice and their reciprocal hybrids. Am J Physiol 1994;267:R1098-108
    • (1994) Am J Physiol , vol.267
    • Dohm, M.R.1    Richardson, C.S.2    Garland, T.3
  • 32
    • 0033680478 scopus 로고    scopus 로고
    • Treadmill running produces both positive and negative physiological adaptations in Sprague-Dawley rats
    • Moraska A, Deak T, Spencer RL, et al: Treadmill running produces both positive and negative physiological adaptations in Sprague-Dawley rats. Am J Physiol Regul Integr Comp Physiol 2000;279: R1321-9
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.279
    • Moraska, A.1    Deak, T.2    Spencer, R.L.3
  • 34
    • 0032828299 scopus 로고    scopus 로고
    • Effect of physical exercise on seizure occurrence in a model of temporal lobe epilepsy in rats
    • DOI 10.1016/S0920-1211(99)00032-7, PII S0920121199000327
    • Arida RM, Scorza FA, Santos NF, et al: Effect of physical exercise on seizure occurrence in a model of temporal lobe epilepsy in rats. Epilepsy Res 1999;37:45-52 (Pubitemid 29413163)
    • (1999) Epilepsy Research , vol.37 , Issue.1 , pp. 45-52
    • Arida, R.M.1    Scorza, F.A.2    Dos Santos, N.F.3    Peres, C.A.4    Cavalheiro, E.A.5
  • 35
    • 35548995887 scopus 로고    scopus 로고
    • Potential therapeutic effects of exercise to the brain
    • DOI 10.2174/092986707782023280
    • Ang ET, Gomez-Pinilla F: Potential therapeutic effects of exercise to the brain. Curr Med Chem 2007;14:2564-71 (Pubitemid 350018469)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.24 , pp. 2564-2571
    • Ang, E.T.1    Gomez-Pinilla, F.2
  • 36
    • 0031019661 scopus 로고    scopus 로고
    • Brain monoamines, exercise, and behavioral stress: Animal models
    • DOI 10.1097/00005768-199701000-00010
    • Dishman RK: Brain monoamines, exercise, and behavioral stress: animal models. Med Sci Sports Exerc 1997;29:63-74 (Pubitemid 27043141)
    • (1997) Medicine and Science in Sports and Exercise , vol.29 , Issue.1 , pp. 63-74
    • Dishman, R.K.1
  • 37
    • 2942624262 scopus 로고    scopus 로고
    • Differential effects of spontaneous versus forced exercise in rats on the staining of parvalbumin-positive neurons in the hippocampal formation
    • DOI 10.1016/j.neulet.2004.03.086, PII S0304394004004677
    • Arida RM, Scorza CA, da Silva AV, et al: Differential effects of spontaneous versus forced exercise in rats on the staining of parvalbumin-positive neurons in the hippocampal formation. Neurosci Lett 2004;364: 135-8 (Pubitemid 38757918)
    • (2004) Neuroscience Letters , vol.364 , Issue.3 , pp. 135-138
    • Arida, R.M.1    Scorza, C.A.2    Da Silva, A.V.3    Scorza, F.A.4    Cavalheiro, E.A.5
  • 38
    • 29044439363 scopus 로고    scopus 로고
    • Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia
    • DOI 10.1016/j.neuroscience.2005.08.037, PII S0306452205009322
    • Ploughman M, Granter-Button S, Chernenko G, et al: Endurance exercise regimens induce differential effects on brain-derived neurotrophic factor, synapsin-I and insulin-like growth factor I after focal ischemia. Neuroscience 2005;136:991-1001 (Pubitemid 41790515)
    • (2005) Neuroscience , vol.136 , Issue.4 , pp. 991-1001
    • Ploughman, M.1    Granter-Button, S.2    Chernenko, G.3    Tucker, B.A.4    Mearow, K.M.5    Corbett, D.6
  • 39
    • 0014613209 scopus 로고
    • Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice
    • Rosenzweig MR, Bennett EL: Effects of differential environments on brain weights and enzyme activities in gerbils, rats, and mice. Dev Psychobiol 1969; 2:87-95
    • (1969) Dev Psychobiol , vol.2 , pp. 87-95
    • Rosenzweig, M.R.1    Bennett, E.L.2
  • 40
    • 0013944804 scopus 로고
    • Increases in cortical depth and glia numbers in rats subjected to enriched environment
    • Diamond MC, Law F, Rhodes H, et al: Increases in cortical depth and glia numbers in rats subjected to enriched environment. J Comp Neurol 1966;128: 117-26
    • (1966) J Comp Neurol , vol.128 , pp. 117-126
    • Diamond, M.C.1    Law, F.2    Rhodes, H.3
  • 41
    • 0036264197 scopus 로고    scopus 로고
    • Effects of enriched environment and fluid percussion injury on dendritic arborization within the cerebral cortex of the developing rat
    • Ip EY, Giza CC, Griesbach GS, et al: Effects of enriched environment and fluid percussion injury on dendritic arborization within the cerebral cortex of the developing rat. J Neurotrauma 2002;19: 573-85 (Pubitemid 34587301)
    • (2002) Journal of Neurotrauma , vol.19 , Issue.5 , pp. 573-585
    • Ip, E.Y.-Y.1    Giza, C.C.2    Griesbach, G.S.3    Hovda, D.A.4
  • 42
    • 0029893652 scopus 로고    scopus 로고
    • Psychobiology of plasticity: Effects of training and experience on brain and behavior
    • DOI 10.1016/0166-4328(95)00216-2
    • Rosenzweig MR, Bennett EL: Psychobiology of plasticity: effects of training and experience on brain and behavior. Behav Brain Res 1996;78:57-65 (Pubitemid 26179783)
    • (1996) Behavioural Brain Research , vol.78 , Issue.1 , pp. 57-65
    • Rosenzweig, M.R.1    Bennett, E.L.2
  • 43
    • 0033135796 scopus 로고    scopus 로고
    • Age-changes of brain synapses and synaptic plasticity in response to an enriched environment
    • DOI 10.1002/(SICI)1097-4547(19990501)56:3<307::AID-JNR10>3.0.CO;2-3
    • Nakamura H, Kobayashi S, Ohashi Y, et al: Agechanges of brain synapses and synaptic plasticity in response to an enriched environment. J Neurosci Res 1999;56:307-15 (Pubitemid 29210621)
    • (1999) Journal of Neuroscience Research , vol.56 , Issue.3 , pp. 307-315
    • Nakamura, H.1    Kobayashi, S.2    Ohashi, Y.3    Ando, S.4
  • 44
    • 0030937293 scopus 로고    scopus 로고
    • More hippocampal neurons in adult mice living in an enriched environment
    • DOI 10.1038/386493a0
    • Kempermann G, Kuhn HG, Gage FH: More hippocampal neurons in adult mice living in an enriched environment. Nature 1997;386:493-5 (Pubitemid 27164074)
    • (1997) Nature , vol.386 , Issue.6624 , pp. 493-495
    • Kempermann, G.1    Kuhn, H.G.2    Gage, F.H.3
  • 45
    • 0034576650 scopus 로고    scopus 로고
    • Neural consequences of environmental enrichment
    • Van Praag H, Kempermann G, Gage FH: Neural consequences of environmental enrichment. Nat Neurosci 2000;1:191-8
    • (2000) Nat Neurosci , vol.1 , pp. 191-198
    • Van Praag, H.1    Kempermann, G.2    Gage, F.H.3
  • 46
    • 0001313209 scopus 로고
    • Enduring brain effects of differential experience and training
    • Rosenzweig MR, Bennett EL, eds. Cambridge, MA: MIT press
    • Greenough WT: Enduring brain effects of differential experience and training. In: Rosenzweig MR, Bennett EL, eds. Neural Mechanisms of Learning and Memory. Cambridge, MA: MIT press; 1976: 255-78
    • (1976) Neural Mechanisms of Learning and Memory , pp. 255-278
    • Greenough, W.T.1
  • 47
    • 0026586247 scopus 로고
    • Exercise and the brain: Angiogenesis in the adult rat cerebellum after vigorous physical activity and motor skill learning
    • Isaacs KR, Anderson BJ, Alcantara AA, et al: Exercise and the brain: angiogenesis in the adult rat cerebellum after vigorous physical activity and motor skill learning. J Cereb Blood Flow Metab 1992; 12:110-9
    • (1992) J Cereb Blood Flow Metab , vol.12 , pp. 110-119
    • Isaacs, K.R.1    Anderson, B.J.2    Alcantara, A.A.3
  • 49
    • 0014596758 scopus 로고
    • The effects of environmental complexity on the histology of the rat hippocampus
    • Walsh RN, Budtz-Olsen OE, Penny JE, et al: The effects of environmental complexity on the histology of the rat hippocampus. J Comp Neurol 1969; 137:361-6
    • (1969) J Comp Neurol , vol.137 , pp. 361-366
    • Walsh, R.N.1    Budtz-Olsen, O.E.2    Penny, J.E.3
  • 50
    • 0021956436 scopus 로고
    • Sex differences in the dendritic branching of dentate granule cells following differential experience
    • DOI 10.1016/0006-8993(85)90125-8
    • Juraska JM, Fitch JM, Henderson C, et al: Sex differences in the dendritic branching of dentate granule cells following differential experience. Brain Res 1985;333:73-80 (Pubitemid 15124350)
    • (1985) Brain Research , vol.333 , Issue.1 , pp. 73-80
    • Juraska, J.M.1    Fitch, J.M.2    Henderson, C.3    Rivers, N.4
  • 51
    • 0034006822 scopus 로고    scopus 로고
    • Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1- knockout mice
    • Rampon C, Tang YP, Goodhouse J, et al: Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1- knockout mice. Nat Neurosci 2000;3:205-6
    • (2000) Nat Neurosci , vol.3 , pp. 205-206
    • Rampon, C.1    Tang, Y.P.2    Goodhouse, J.3
  • 52
    • 0033539607 scopus 로고    scopus 로고
    • Running enhances neurogenesis, learning, and long-term potentiation in mice
    • Van Praag H, Christie BR, Sejnowski TJ, et al: Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci 1999;96:13427-31
    • (1999) Proc Natl Acad Sci , vol.96 , pp. 13427-13431
    • Van Praag, H.1    Christie, B.R.2    Sejnowski, T.J.3
  • 53
    • 0035283153 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult hippocampus
    • Trejo JL, Carro E, Torres-Aleman I: Circulating insulin-like growth factor I mediates exerciseinduced increases in the number of new neurons in the adult. J Neurosci 2001;21:1628-34 (Pubitemid 32182203)
    • (2001) Journal of Neuroscience , vol.21 , Issue.5 , pp. 1628-1634
    • Trejo, J.L.1    Carro, E.2    Torres-Aleman, I.3
  • 54
    • 0037305348 scopus 로고    scopus 로고
    • Magnitude- and time-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats
    • Kim YP, Kim HB, Jang MH, et al: Magnitude- and time-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats. Int J Sports Med 2003;24:114-7
    • (2003) Int J Sports Med , vol.24 , pp. 114-117
    • Kim, Y.P.1    Kim, H.B.2    Jang, M.H.3
  • 55
    • 53249149104 scopus 로고    scopus 로고
    • Forced and voluntary exercise differentially affect brain and behavior
    • Leasure JL, Jones M: Forced and voluntary exercise differentially affect brain and behavior. Neuroscience 2008;156:456-65
    • (2008) Neuroscience , vol.156 , pp. 456-465
    • Leasure, J.L.1    Jones, M.2
  • 58
    • 67949114536 scopus 로고    scopus 로고
    • Physical exercise leads to rapid adaptations in hippocampal vasculature: Temporal dynamics and relationship to cell proliferation and neurogenesis
    • Van der Borght K, Kóbor-Nyakas DE, Klauke K, et al: Physical exercise leads to rapid adaptations in hippocampal vasculature: temporal dynamics and relationship to cell proliferation and neurogenesis. Hippocampus 2009;19:928-36
    • (2009) Hippocampus , vol.19 , pp. 928-936
    • Van Der Borght, K.1    Kóbor-Nyakas, D.E.2    Klauke, K.3
  • 59
    • 0347689968 scopus 로고    scopus 로고
    • Preischemic motor exercise reduces ischemia/reperfusion injury in rats that correlated with regional angiogenesis and cellular expression of neurotrophin
    • Ding Y, Li J, Rafols JA, et al: Preischemic motor exercise reduces ischemia/reperfusion injury in rats that correlated with regional angiogenesis and cellular expression of neurotrophin. Stroke 2003; 34:240-1
    • (2003) Stroke , vol.34 , pp. 240-241
    • Ding, Y.1    Li, J.2    Rafols, J.A.3
  • 60
    • 0032957382 scopus 로고    scopus 로고
    • Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective
    • DOI 10.1038/7449
    • Young D, Lawlor PA, Leone P, et al: Environmental enrichment inhibits spontaneous apoptosis, prevents seizures and is neuroprotective. Nat Med 1999;5:448-53 (Pubitemid 29180587)
    • (1999) Nature Medicine , vol.5 , Issue.4 , pp. 448-453
    • Young, D.1    Lawlor, P.A.2    Leone, P.3    Dragunow, M.4    During, M.J.5
  • 61
    • 33244466061 scopus 로고    scopus 로고
    • Influence of differential housing on emotional behaviour and neurotrophin levels in mice
    • DOI 10.1016/j.bbr.2005.11.024, PII S0166432805005176
    • Zhu SW, Yee BK, Nyffeler M, et al: Influence of differential housing on emotional behaviour and neurotrophin levels in mice. Behav Brain Res 2006; 169:10-20 (Pubitemid 43277466)
    • (2006) Behavioural Brain Research , vol.169 , Issue.1 , pp. 10-20
    • Zhu, S.-W.1    Yee, B.K.2    Nyffeler, M.3    Winblad, B.4    Feldon, J.5    Mohammed, A.H.6
  • 62
    • 18144440012 scopus 로고    scopus 로고
    • Environmental enrichment results in higher levels of nerve growth factor mRNA in the rat visual cortex and hippocampus
    • DOI 10.1016/S0166-4328(97)00142-3, PII S0166432897001423
    • Torasdotter M, Metsis M, Henriksson BG, et al: Environmental enrichment results in higher levels of nerve growth factor mRNA in the rat visual cortex and hippocampus. Behav Brain Res 1998;93:83-90 (Pubitemid 28289427)
    • (1998) Behavioural Brain Research , vol.93 , Issue.1-2 , pp. 83-90
    • Torasdotter, M.1    Metsis, M.2    Henriksson, B.G.3    Bengt Winblad4    Mohammed, A.H.5
  • 64
    • 33645865549 scopus 로고    scopus 로고
    • VEGF, a mediator of the effect of experience on hippocampal neurogenesis
    • During MJ, Cao L: VEGF, a mediator of the effect of experience on hippocampal neurogenesis. Curr Alzheimer Res 2006;3:29-33
    • (2006) Curr Alzheimer Res , vol.3 , pp. 29-33
    • During, M.J.1    Cao, L.2
  • 66
    • 2442475297 scopus 로고    scopus 로고
    • The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise
    • DOI 10.1016/j.neulet.2004.03.058, PII S0304394004003659
    • Adlard PA, Perreau VM, Engesser-Cesar C, et al: The timecourse of induction of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus following voluntary exercise. Neurosci Lett 2004;363:43-8 (Pubitemid 38639848)
    • (2004) Neuroscience Letters , vol.363 , Issue.1 , pp. 43-48
    • Adlard, P.A.1    Perreau, V.M.2    Engesser-Cesar, C.3    Cotman, C.W.4
  • 67
    • 0010330438 scopus 로고    scopus 로고
    • Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain
    • DOI 10.1016/S0006-8993(96)00273-9
    • Neeper SA, Gomez-Pinilla F, Choi J, et al: Physical activity increases mRNA for brain-derived neurotrophic factor and nerve growth factor in rat brain. Brain Res 1996;726:49-56 (Pubitemid 26292229)
    • (1996) Brain Research , vol.726 , Issue.1-2 , pp. 49-56
    • Neeper, S.A.1    Gomez-Pinilla, F.2    Choi, J.3    Cotman, C.W.4
  • 68
    • 1442316352 scopus 로고    scopus 로고
    • Differential effects of acute and chronic exercise on plasticity-related genes in the rat hippocampus revealed by microarray
    • DOI 10.1046/j.1460-9568.2002.02158.x
    • Molteni R, Ying Z, Gomez-Pinilla F: Differential effects of acute and chronic exercise on plasticityrelated genes in the rat hippocampus revealed by microarray. Eur J Neurosci 2002;16:1107-16 (Pubitemid 35463560)
    • (2002) European Journal of Neuroscience , vol.16 , Issue.6 , pp. 1107-1116
    • Molteni, R.1    Ying, Z.2    Gomez-Pinilla, F.3
  • 69
    • 0028970281 scopus 로고
    • Stress and glucocorticoids affect the expression of brainderived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus
    • Smith MA, Makino S, Kvetnansky R, et al: Stress and glucocorticoids affect the expression of brainderived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus. J Neurosci 1995;15: 1768-77
    • (1995) J Neurosci , vol.15 , pp. 1768-1777
    • Smith, M.A.1    Makino, S.2    Kvetnansky, R.3
  • 70
    • 33745495507 scopus 로고    scopus 로고
    • Compulsive exercise acutely upregulates rat hippocampal brain-derived neurotrophic factor
    • DOI 10.1007/s00702-005-0359-4
    • Huang AM, Jen CJ, Chen HF, et al: Compulsive exercise acutely upregulates rat hippocampal brainderived neurotrophic factor. J Neural Transm 2006; 113:803-11 (Pubitemid 43962775)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.7 , pp. 803-811
    • Huang, A.M.1    Jen, C.J.2    Chen, H.F.3    Yu, L.4    Kuo, Y.M.5    Chen, H.I.6
  • 71
    • 0031656199 scopus 로고    scopus 로고
    • Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: A mechanism to facilitate encoding and circuit maintenance?
    • DOI 10.1037//0735-7044.112.4.1012
    • Kesslak JP, So V, Choi J, et al: Learning upregulates brain-derived neurotrophic factor messenger ribonucleic acid: a mechanism to facilitate encoding and circuit maintenance? Behav Neurosci 1998; 112:1012-9 (Pubitemid 28397383)
    • (1998) Behavioral Neuroscience , vol.112 , Issue.4 , pp. 1012-1019
    • Patrick Kesslak, J.1    So, V.2    Choi, J.3    Cotman, C.W.4    Gomez-Pinilla, F.5
  • 72
    • 0035826517 scopus 로고    scopus 로고
    • Physical activity-antidepressant treatment combination: Impact on brain-derived neurotrophic factor and behavior in an animal model
    • DOI 10.1016/S0166-4328(00)00364-8, PII S0166432800003648
    • Russo-Neustadt A, Ha T, Ramirez R, et al: Physical activity- antidepressant treatment combination: impact on brain-derived neurotrophic factor and behavior in an animal model. Behav Brain Res 2001; 120:87-95 (Pubitemid 32118151)
    • (2001) Behavioural Brain Research , vol.120 , Issue.1 , pp. 87-95
    • Russo-Neustadt, A.1    Ha, T.2    Ramirez, R.3    Kesslak, J.P.4
  • 73
    • 0030982311 scopus 로고    scopus 로고
    • Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrin areas
    • DOI 10.1016/S0028-3908(97)00048-8, PII S0028390897000488
    • Adell A, Casanovas JM, Artigas F: Comparative study in the rat of the actions of different types of stress on the release of 5-HT in raphe nuclei and forebrain areas. Neuropharmacology 1997;36: 735-41 (Pubitemid 27273213)
    • (1997) Neuropharmacology , vol.36 , Issue.4-5 , pp. 735-741
    • Adell, A.1    Casanovas, J.M.2    Artigas, F.3
  • 74
    • 0025761884 scopus 로고
    • Physical activity effects on hippocampal and parietal cortical cholinergic function and spatial learning in F344 rats
    • Fordyce DE, Farrar RP: Physical activity effects on hippocampal and parietal cortical cholinergic function and spatial learning in F344 rats. Behav Brain Res 1991;43:115-23
    • (1991) Behav Brain Res , vol.43 , pp. 115-123
    • Fordyce, D.E.1    Farrar, R.P.2
  • 75
    • 0024450802 scopus 로고
    • Physical exercise and brain monoamines: A review
    • Chaouloff F: Physical exercise and brain monoamines: a review. Acta Physiol Scand 1989;137: 1-13 (Pubitemid 19228051)
    • (1989) Acta Physiologica Scandinavica , vol.137 , Issue.1 , pp. 1-13
    • Chaouloff, F.1
  • 77
    • 0014499861 scopus 로고
    • Hippocampal electrical activity and voluntary movement in the rat
    • Vanderwolf CH: Hippocampal electrical activity and voluntary movement in the rat. Electroencephalogr Clin Neurophysiol 1969;26:407-18
    • (1969) Electroencephalogr Clin Neurophysiol , vol.26 , pp. 407-418
    • Vanderwolf, C.H.1
  • 78
    • 0032923405 scopus 로고    scopus 로고
    • Sustained activation of hippocampal pyramidal cells by Fspace clamping in a running wheel
    • Czurko A, Hirase H, Csicsvari J, et al: Sustained activation of hippocampal pyramidal cells by Fspace clamping in a running wheel. Eur J Neurosci 1999; 11:344-52
    • (1999) Eur J Neurosci , vol.11 , pp. 344-352
    • Czurko, A.1    Hirase, H.2    Csicsvari, J.3
  • 79
    • 0027476024 scopus 로고
    • A synaptic model of memory: Long-term potentiation in the hippocampus
    • DOI 10.1038/361031a0
    • Bliss TV, Collingridge GL: A synaptic model of memory: long-term potentiation in the hippocampus. Nature 1993;361:31-9 (Pubitemid 23020772)
    • (1993) Nature , vol.361 , Issue.6407 , pp. 31-39
    • Bliss, T.V.P.1    Collingridge, G.L.2
  • 80
    • 0442307920 scopus 로고    scopus 로고
    • Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male sprague-dawley rats in vivo
    • DOI 10.1016/j.neuroscience.2003.09.029
    • Farmer J, Zhao X, Van Praag H, et al: Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo. Neuroscience 2004; 124:71-9 (Pubitemid 38186618)
    • (2004) Neuroscience , vol.124 , Issue.1 , pp. 71-79
    • Farmer, J.1    Zhao, X.2    Van Praag, H.3    Wodtke, K.4    Gage, F.H.5    Christie, B.R.6
  • 81
    • 33845283925 scopus 로고    scopus 로고
    • The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial- and non-spatial learning
    • DOI 10.1016/j.bbr.2006.10.018, PII S0166432806005626
    • O'Callaghan RM, Ohle R, Kelly AM: The effects of forced exercise on hippocampal plasticity in the rat: a comparison of LTP, spatial- and non-spatial learning. Behav Brain Res 2007;176:362-6 (Pubitemid 44880096)
    • (2007) Behavioural Brain Research , vol.176 , Issue.2 , pp. 362-366
    • O'Callaghan, R.M.1    Ohle, R.2    Kelly, A.M.3
  • 82
    • 0021886551 scopus 로고
    • Enhancement of hippocampal field potentials in rats exposed to a novel, complex environment
    • DOI 10.1016/0006-8993(85)90105-2
    • Sharp PE, McNaughton BL, Barnes CA: Enhancement of hippocampal field potentials in rats exposed to a novel, complex environment. Brain Res 1985; 339:361-5 (Pubitemid 15037006)
    • (1985) Brain Research , vol.339 , Issue.2 , pp. 361-365
    • Sharp, P.E.1    McNaughton, B.L.2    Barnes, C.A.3
  • 83
    • 0034213060 scopus 로고    scopus 로고
    • Recovery recapitulates ontogeny
    • DOI 10.1016/S0166-2236(00)01562-9, PII S0166223600015629
    • Cramer SC, Chopp M: Recovery recapitulates ontogeny. Trends Neurosci 2000;23:265-71 (Pubitemid 30331113)
    • (2000) Trends in Neurosciences , vol.23 , Issue.6 , pp. 265-271
    • Cramer, S.C.1    Chopp, M.2
  • 84
    • 0036602967 scopus 로고    scopus 로고
    • Exercise: A behavioral intervention to enhance brain health and plasticity
    • DOI 10.1016/S0166-2236(02)02143-4, PII S0166223602021434
    • Cotman CW, Berchtold NC: Exercise: a behavioral intervention to enhance brain health and plasticity. Trends Neurosci 2002;25:295-301 (Pubitemid 34667010)
    • (2002) Trends in Neurosciences , vol.25 , Issue.6 , pp. 295-301
    • Cotman, C.W.1    Berchtold, N.C.2
  • 89
    • 0035426212 scopus 로고    scopus 로고
    • Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy
    • Carro E, Trejo JL, Busiguina S, et al: Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. J Neurosci 2001;21: 5678-84 (Pubitemid 32692166)
    • (2001) Journal of Neuroscience , vol.21 , Issue.15 , pp. 5678-5684
    • Carro, E.1    Trejo, J.L.2    Busiguina, S.3    Torres-Aleman, I.4
  • 90
    • 0030158237 scopus 로고    scopus 로고
    • Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat
    • DOI 10.1006/exnr.1996.0106
    • Johansson BB, Ohlsson AL: Environment, social interaction, and physical activity as determinants of functional outcome after cerebral infarction in the rat. Exp Neurol 1996;139:322-7 (Pubitemid 26228100)
    • (1996) Experimental Neurology , vol.139 , Issue.2 , pp. 322-327
    • Johansson, B.B.1    Ohlsson, A.-L.2
  • 91
    • 0035031904 scopus 로고    scopus 로고
    • Recovery of locomotor function after treadmill training of incomplete spinal cord injured rats
    • Thota A, Carlson S, Jung R: Recovery of locomotor function after treadmill training of incomplete spinal cord injured rats. Biomed Sci Instrum 2001; 37:63-7 (Pubitemid 32381417)
    • (2001) Biomedical Sciences Instrumentation , vol.37 , pp. 63-67
    • Thota, A.1    Carlson, S.2    Jung, R.3
  • 93
    • 0012849885 scopus 로고    scopus 로고
    • Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
    • DOI 10.1016/S0306-4522(03)00096-4
    • Tillerson JL, Caudle WM, Reveron ME, et al: Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease. Neuroscience 2003;119:899-911 (Pubitemid 36694814)
    • (2003) Neuroscience , vol.119 , Issue.3 , pp. 899-911
    • Tillerson, J.L.1    Caudle, W.M.2    Reveron, M.E.3    Miller, G.W.4
  • 94
    • 3242675431 scopus 로고    scopus 로고
    • Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundle
    • DOI 10.1023/B:MEBR.0000027416.13070.c3
    • Mabandla M, Kellaway L, St Clair Gibson A, et al: Voluntary running provides neuroprotection in rats after 6-hydroxydopamine injection into the medial forebrain bundle. Metab Brain Dis 2004;19:43-50 (Pubitemid 39005624)
    • (2004) Metabolic Brain Disease , vol.19 , Issue.1-2 , pp. 43-50
    • Mabandla, M.1    Kellaway, L.2    Gibson, A.St.C.3    Russell, V.A.4
  • 95
    • 27644481341 scopus 로고    scopus 로고
    • Stress reduces the neuroprotective effect of exercise in a rat model for Parkinson's disease
    • DOI 10.1016/j.bbr.2005.06.044, PII S0166432805002998
    • Howells FM, Russell VA, Mabandla MV, et al: Stress reduces the neuroprotective effect of exercise in a rat model for Parkinson's disease. Behav Brain Res 2005;165:210-20 (Pubitemid 41565531)
    • (2005) Behavioural Brain Research , vol.165 , Issue.2 , pp. 210-220
    • Howells, F.M.1    Russell, V.A.2    Mabandla, M.V.3    Kellaway, L.A.4
  • 96
    • 3543066405 scopus 로고    scopus 로고
    • Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine
    • DOI 10.1016/j.expneurol.2004.05.012, PII S0014488604001864
    • Moroz IA, Pecina S, Schallert T, et al: Sparing of behavior and basal extracellular dopamine after 6-hydroxydopamine lesions of the nigrostriatal pathway in rats exposed to a prelesion sensitizing regimen of amphetamine. Exp Neurol 2004;189: 78-93 (Pubitemid 39024457)
    • (2004) Experimental Neurology , vol.189 , Issue.1 , pp. 78-93
    • Moroz, I.A.1    Pecina, S.2    Schallert, T.3    Stewart, J.4
  • 97
    • 33845796526 scopus 로고    scopus 로고
    • Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection
    • DOI 10.1016/j.neuroscience.2006.10.042, PII S0306452206014680
    • O'Dell SJ, Gross NB, Fricks AN, et al: Running wheel exercise enhances recovery from nigrostriatal dopamine injury without inducing neuroprotection. Neuroscience 2007;144:1141-51 (Pubitemid 46014003)
    • (2007) Neuroscience , vol.144 , Issue.3 , pp. 1141-1151
    • O'Dell, S.J.1    Gross, N.B.2    Fricks, A.N.3    Casiano, B.D.4    Nguyen, T.B.5    Marshall, J.F.6
  • 98
    • 64149107612 scopus 로고    scopus 로고
    • Enriched environment protects the nigrostriatal dopaminergic system and induces astroglial reaction in the 6-OHDA rat model of Parkinson's disease
    • Anastasía A, Torre L, de Erausquin GA, et al: Enriched environment protects the nigrostriatal dopaminergic system and induces astroglial reaction in the 6-OHDA rat model of Parkinson's disease. J Neurochem 2009;109:755-65
    • (2009) J Neurochem , vol.109 , pp. 755-765
    • Anastasía, A.1    Torre, L.2    De Erausquin, G.A.3
  • 100
    • 33745267260 scopus 로고    scopus 로고
    • Enriched environment improves motor function in intact and unilateral dopamine-depleted rats
    • DOI 10.1016/j.neuroscience.2006.03.027, PII S0306452206003812
    • Jadavji N, Kolb B, Metz G: Enriched environment improves motor function in intact and unilateral dopamine-depleted rats. Neuroscience 2006;140: 1127-38 (Pubitemid 43928283)
    • (2006) Neuroscience , vol.140 , Issue.4 , pp. 1127-1138
    • Jadavji, N.M.1    Kolb, B.2    Metz, G.A.3
  • 101
    • 18244384051 scopus 로고    scopus 로고
    • Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
    • DOI 10.1523/JNEUROSCI.0496-05.2005
    • Adlard PA, Perreau VM, Pop V, et al: Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci 2005;25: 4217-21 (Pubitemid 40628765)
    • (2005) Journal of Neuroscience , vol.25 , Issue.17 , pp. 4217-4221
    • Adlard, P.A.1    Perreau, V.M.2    Pop, V.3    Cotman, C.W.4
  • 102
    • 33751550928 scopus 로고    scopus 로고
    • Cognitive and Physical Activity Differently Modulate Disease Progression in the Amyloid Precursor Protein (APP)-23 Model of Alzheimer's Disease
    • DOI 10.1016/j.biopsych.2006.04.004, PII S0006322306004665
    • Wolf SA, Kronenberg G, Lehmann K, et al: Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease. Biol Psychiatry 2006;60:1314-23 (Pubitemid 44838527)
    • (2006) Biological Psychiatry , vol.60 , Issue.12 , pp. 1314-1323
    • Wolf, S.A.1    Kronenberg, G.2    Lehmann, K.3    Blankenship, A.4    Overall, R.5    Staufenbiel, M.6    Kempermann, G.7
  • 103
    • 41949084054 scopus 로고    scopus 로고
    • Wheelrunning in a transgenic mouse model of Alzheimer's disease: Protection or symptom?
    • Richter H, Ambrée O, Lewejohann L, et al: Wheelrunning in a transgenic mouse model of Alzheimer's disease: protection or symptom? Behav Brain Res 2008;190:74-84
    • (2008) Behav Brain Res , vol.190 , pp. 74-84
    • Richter, H.1    Ambrée, O.2    Lewejohann, L.3
  • 106
    • 0023069652 scopus 로고
    • Reorganization of neocortical representations after brain injury: A neurophysiological model of the bases of recovery from stroke
    • Jenkins WM, Merzenich MM: Reorganization of neocortical representations after brain injury: a neurophysiological model of the bases of recovery from stroke. Prog Brain Res 1987;71:249j66
    • (1987) Prog Brain Res , vol.71
    • Jenkins, W.M.1    Merzenich, M.M.2
  • 107
    • 0030931363 scopus 로고    scopus 로고
    • Adaptive plasticity in primate motor cortex as a consequence of behavioral experience and neuronal injury
    • Nudo RJ, Plautz EJ, Milliken GW: Adaptive plasticity in primate motor cortex as a consequence of behavioral experience and neuronal injury. Semin Neurosci 1997;9:13j23
    • (1997) Semin Neurosci , vol.9
    • Nudo, R.J.1    Plautz, E.J.2    Milliken, G.W.3
  • 108
    • 0030771610 scopus 로고    scopus 로고
    • Behavioral, anatomical, and physiological aspects of recovery of motor function following stroke
    • Steinberg BA, Augustine JR. Behavioral, anatomical, and physiological aspects of recovery of motor function following stroke. Brain Res Rev 1997;25: 125j32
    • (1997) Brain Res Rev , vol.25
    • Steinberg, B.A.1    Augustine, J.R.2
  • 109
    • 0029936118 scopus 로고    scopus 로고
    • Electrophysiological transcortical diaschisis after cortical photothrombosis in rat brain
    • Buchkremer-Ratzmann I, August M, Hagemann G, et al: Electrophysiological transcortical diaschisis after cortical photothrombosis in rat brain. Stroke 1996;27:1105-9
    • (1996) Stroke , vol.27 , pp. 1105-1109
    • Buchkremer-Ratzmann, I.1    August, M.2    Hagemann, G.3
  • 111
    • 0030017218 scopus 로고    scopus 로고
    • Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct
    • Nudo RJ, Wise BM, SiFuentes F, et al: Neural substrates for the effects of rehabilitative training on motor recovery after ischemic infarct. Science 1996; 272:1791j4
    • (1996) Science , vol.272
    • Nudo, R.J.1    Wise, B.M.2    Sifuentes, F.3
  • 112
    • 0031937575 scopus 로고    scopus 로고
    • Use-dependent exacerbation of brain damage occurs during an early post- lesion vulnerable period
    • DOI 10.1016/S0006-8993(97)01356-5, PII S0006899397013565
    • Humm JL, Kozlowski DA, James DC, et al: Usedependent exacerbation of brain damage occurs during an early post-lesion vulnerable period. Brain Res 1998;783:286-92 (Pubitemid 28131409)
    • (1998) Brain Research , vol.783 , Issue.2 , pp. 286-292
    • Humm, J.L.1    Kozlowski, D.A.2    James, D.C.3    Gotts, J.E.4    Schallert, T.5
  • 113
    • 75949119833 scopus 로고    scopus 로고
    • Early treadmill training promotes motor function after hemorrhagic stroke in rats
    • Park JW, Bang MS, Kwon BS, et al: Early treadmill training promotes motor function after hemorrhagic stroke in rats. Neurosci Lett 2010;471: 104-8
    • (2010) Neurosci Lett , vol.471 , pp. 104-108
    • Park, J.W.1    Bang, M.S.2    Kwon, B.S.3
  • 114
    • 0034953320 scopus 로고    scopus 로고
    • Role of adaptive plasticity in recovery of function after damage to motor cortex
    • DOI 10.1002/mus.1104
    • Nudo RJ, Plautz EJ, Frost SB: Role of adaptive plasticity in recovery of function after damage to motor cortex. Muscle Nerve 2001;24:1000-19 (Pubitemid 32656186)
    • (2001) Muscle and Nerve , vol.24 , Issue.8 , pp. 1000-1019
    • Nudo, R.J.1    Plautz, E.J.2    Frost, S.B.3
  • 115
    • 0031441292 scopus 로고    scopus 로고
    • Predisposing factors to enlargement of spontaneous intracerebral hematoma
    • Kazui S, Minematsu K, Yamamoto H, et al: Predisposing factors to enlargement of spontaneous intracerebral hematoma. Stroke 1997;28:2370-5 (Pubitemid 28007634)
    • (1997) Stroke , vol.28 , Issue.12 , pp. 2370-2375
    • Kazui, S.1    Minematsu, K.2    Yamamoto, H.3    Sawada, T.4    Yamaguchi, T.5
  • 116
    • 70349522307 scopus 로고    scopus 로고
    • Impact of training on changes in perceived stress and cytokine production
    • Main LC, Dawson B, Grove JR, et al: Impact of training on changes in perceived stress and cytokine production. Res Sports Med 2009;17:121-32
    • (2009) Res Sports Med , vol.17 , pp. 121-132
    • Main, L.C.1    Dawson, B.2    Grove, J.R.3
  • 117
    • 0003096042 scopus 로고    scopus 로고
    • Systemic inflammatory response to exhaustive exercise. Cytokine kinetics
    • Suzuki K, Nakaji S, Yamada M, et al: Systemic inflammatory response to exhaustive exercise. Cytokine kinetics. Exerc Immunol Rev 2002;8:6-48
    • (2002) Exerc Immunol Rev , vol.8 , pp. 6-48
    • Suzuki, K.1    Nakaji, S.2    Yamada, M.3
  • 118
    • 0033974030 scopus 로고    scopus 로고
    • Cytokine hypothesis of overtraining: A physiological adaptation to excessive stress?
    • Smith LL: Cytokine hypothesis of overtraining: a physiological adaptation to excessive stress? Med Sci Sports Exerc 2000;32:317-31 (Pubitemid 30108110)
    • (2000) Medicine and Science in Sports and Exercise , vol.32 , Issue.2 , pp. 317-331
    • Smith, L.L.1
  • 119
    • 15444374348 scopus 로고    scopus 로고
    • The anti-inflammatory effect of exercise
    • DOI 10.1152/japplphysiol.00164.2004
    • Petersen AM, Pedersen BK: The anti-inflammatory effect of exercise. J Appl Physiol 2005;98:1154-62 (Pubitemid 40396484)
    • (2005) Journal of Applied Physiology , vol.98 , Issue.4 , pp. 1154-1162
    • Petersen, A.M.W.1    Pedersen, B.K.2
  • 120
    • 45549092076 scopus 로고    scopus 로고
    • Physical activity and epilepsy: Proven and predicted benefits
    • DOI 10.2165/00007256-200838070-00006
    • Arida RM, Cavalheiro EA, da Silva AC, et al: Physical activity and epilepsy: proven and predicted benefits. Sports Med 2008;38:607-15 (Pubitemid 351861947)
    • (2008) Sports Medicine , vol.38 , Issue.7 , pp. 607-615
    • Arida, R.M.1    Cavalheiro, E.A.2    Da Silva, A.C.3    Scorza, F.A.4
  • 121
    • 59249108040 scopus 로고    scopus 로고
    • Is physical activity beneficial for recovery in temporal lobe epilepsy? Evidences from animal studies
    • Arida RM, Scorza FA, Scorza CA, et al: Is physical activity beneficial for recovery in temporal lobe epilepsy? Evidences from animal studies. Neurosci Biobehav 2009;33:422-31
    • (2009) Neurosci Biobehav , vol.33 , pp. 422-431
    • Arida, R.M.1    Scorza, F.A.2    Scorza, C.A.3
  • 122
    • 0031966916 scopus 로고    scopus 로고
    • Effect of physical exercise on kindling development
    • DOI 10.1016/S0920-1211(97)00102-2, PII S0920121197001022
    • Arida RM, Vieira AJ, Cavalheiro EA: Effect of physical exercise on kindling development. Epilepsy Res 1998;30:127-32 (Pubitemid 28198241)
    • (1998) Epilepsy Research , vol.30 , Issue.2 , pp. 127-132
    • Arida, R.M.1    De Jesus Vieira, A.2    Cavalheiro, E.A.3
  • 124
    • 6344258366 scopus 로고    scopus 로고
    • Physical training reverts hippocampal electrophysiological changes in rats submitted to the pilocarpine model of epilepsy
    • DOI 10.1016/j.physbeh.2004.08.008, PII S0031938404003385
    • Arida RM, Sanabria ERG, Silva AC, et al: Physical training reverts hippocampal electrophysiological changes in rats submitted to the pilocarpine model of epilepsy. Physiol Behav 2004;83:165-71 (Pubitemid 39387706)
    • (2004) Physiology and Behavior , vol.83 , Issue.1 SPEC. ISS. , pp. 165-171
    • Arida, R.M.1    Sanabria, E.R.G.2    Da Silva, A.C.3    Faria, L.C.4    Scorza, F.A.5    Cavalheiro, E.A.6
  • 126
    • 33748807206 scopus 로고    scopus 로고
    • Physical training decreases susceptibility to subsequent pilocarpine-induced seizures in the rat
    • DOI 10.1016/j.eplepsyres.2006.06.002, PII S0920121106002154
    • Setkowicz Z, Mazur A: Physical training decreases susceptibility to subsequent pilocarpine-induced seizures in the rat. Epilepsy Res 2006;71:142-8 (Pubitemid 44416191)
    • (2006) Epilepsy Research , vol.71 , Issue.2-3 , pp. 142-148
    • Setkowicz, Z.1    Mazur, A.2
  • 127
    • 0346037311 scopus 로고    scopus 로고
    • Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion
    • DOI 10.1016/S0006-8993(03)02365-5
    • Ramsden M, Berchtold NC, Kesslak JP, et al: Exercise increases the vulnerability of rat hippocampal neurons to kainate lesion. Brain Res 2003;971: 239-44 (Pubitemid 36423325)
    • (2003) Brain Research , vol.971 , Issue.2 , pp. 239-244
    • Ramsden, M.1    Berchtold, N.C.2    Patrick Kesslak, J.3    Cotman, C.W.4    Pike, C.J.5
  • 128
    • 0028086162 scopus 로고
    • Reduced mortality and brain damage after locomotor activity in gerbil forebrain ischemia
    • Stummer W, Weber K, Tranmer B, et al: Reduced mortality and brain damage after locomotor activity in gerbil forebrain ischemia. Stroke 1994;25:1862-9 (Pubitemid 24274985)
    • (1994) Stroke , vol.25 , Issue.9 , pp. 1862-1869
    • Stummer, W.1    Weber, K.2    Tranmer, B.3    Baethmann, A.4    Kempski, O.5
  • 129
    • 0037044877 scopus 로고    scopus 로고
    • Delayed kindling epileptogenesis and increased neurogenesis in adult rats housed in an enriched environment
    • DOI 10.1016/S0006-8993(02)03355-3, PII S0006899302033553
    • Auvergne R, Leré C, El Bahh B, et al: Delayed kindling epileptogenesis and increased neurogenesis in adult rats housed in an enriched environment. Brain Res 2002;954:277-85 (Pubitemid 35284667)
    • (2002) Brain Research , vol.954 , Issue.2 , pp. 277-285
    • Auvergne, R.1    Lere, C.2    El Bahh, B.3    Arthaud, S.4    Lespinet, V.5    Rougier, A.6    Le Gal La Salle, G.7
  • 130
    • 15744391499 scopus 로고    scopus 로고
    • Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor
    • DOI 10.1016/j.bbr.2004.09.021
    • Gobbo OL, O'Mara SM: Exercise, but not environmental enrichment, improves learning after kainic acid-induced hippocampal neurodegeneration in association with an increase in brain-derived neurotrophic factor. Behav Brain Res 2005;159:21-6 (Pubitemid 40410581)
    • (2005) Behavioural Brain Research , vol.159 , Issue.1 , pp. 21-26
    • Gobbo, O.L.1    O'Mara, S.M.2
  • 131
    • 67649643785 scopus 로고    scopus 로고
    • Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus
    • Sartori CR, Pelágio FC, Teixeira SA, et al: Effects of voluntary running on spatial memory and mature brain-derived neurotrophic factor expression in mice hippocampus after status epilepticus. Behav Brain Res 2009;203:165-72
    • (2009) Behav Brain Res , vol.203 , pp. 165-172
    • Sartori, C.R.1    Pelágio, F.C.2    Teixeira, S.A.3
  • 132
    • 0026340904 scopus 로고
    • Longterm effects of pilocarpine in rats: Structural damage of the brain triggers kindling and spontaneous recurrent seizures
    • Cavalheiro EA, Leite JP, Bortolotto ZA, et al: Longterm effects of pilocarpine in rats: structural damage of the brain triggers kindling and spontaneous recurrent seizures. Epilepsia 1991;32:778-82
    • (1991) Epilepsia , vol.32 , pp. 778-782
    • Cavalheiro, E.A.1    Leite, J.P.2    Bortolotto, Z.A.3
  • 133
    • 34548499151 scopus 로고    scopus 로고
    • Exercise builds brain health: Key roles of growth factor cascades and inflammation
    • DOI 10.1016/j.tins.2007.06.011, PII S0166223607001786
    • Cotman CW, Berchtold NC, Christie LA: Exercise builds brain health: key roles of growth factor cascades and inflammation. Trends Neurosci 2007;30: 464-72 (Pubitemid 47374831)
    • (2007) Trends in Neurosciences , vol.30 , Issue.9 , pp. 464-472
    • Cotman, C.W.1    Berchtold, N.C.2    Christie, L.-A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.