Magnitude- and time-dependence of the effect of treadmill exercise on cell proliferation in the dentate gyrus of rats

International Journal of Sports Medicine

Volumn 24, Issue 2, 2003, Pages 114-117

  Kim, Y P ^a   Kim, H B ^a   Jang, M H ^a   Lim, B V ^a   Kim, Y J ^a   Kim, H ^b   Kim, S S ^b   Kim, E H ^c   Kim, C J ^a  

^a Kyung Hee University Hospital   (South Korea)

^b Korea University   (South Korea)

^c Semyung University   (South Korea)

Author keywords

5 bromo 2 deoxyuridine; Cell proliferation; Dentate gyrus; Exercise duration; Exercise intensity; Immunohistochemisty; Treadmill exercise

Indexed keywords

BROXURIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; DENTATE GYRUS; EXERCISE; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL DIFFERENTIATION; NERVE CELL GROWTH; NONHUMAN; RAT; TIME SERIES ANALYSIS; TREADMILL;

ANIMALS; BROMODEOXYURIDINE; DENTATE GYRUS; IMMUNOHISTOCHEMISTRY; MALE; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 0037305348     PISSN: 01724622     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-38202     Document Type: Article

References (15)

1. Altman J, Bayer SA. Migration and distribution of two populations of hippocampal granule cell precursors during the perinatal and postnatal period. J Comp Neural 1990; 301: 365-381
2. Borer KT, Bestervelt LL, Mannheim M, Brosamer MB, Thompson M, Swamy U, Piper WN. Stimulation by voluntary exercise of adrenal glucocorticoid secretion in mature female hamsters. Physiol Behav 1992; 51: 713-718
3. Cameron HA, McKay RDG. Restoring production of hippocampal neurons in old age. Nature Neurosci 1999; 2: 894-897
4. Cameron HA, Tanapat P, Gould E. Adrenal steroids and N-methyl-D-aspartate receptor activation regulate neurogenesis in the dentate gyrus of adult rats through a common pathway. Neuroscience 1998; 82: 349-354
5. Eriksson PS, Perfilieva E, Bjork-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH. Neurogenesis in the adult human hippocampus. Nat Med 1998; 4: 1313-1317
6. Gage FH, Kempermann G, Palmer TD, Peterson DA, Ray J. Multipotent progenitor cells in the adult dentate gyrus. J Neurobiol 1998; 36: 249-266
7. Gómez-Pinilla F, So V, Kesslak JP. Spatial learning and physical activity contribute to the induction of fibroblast growth factor: neural substrates for increased cognition associated with exercise. Neuroscience 1998; 85: 53-61
8. Gould E, Beylin A, Tanapat P, Reeves A, Shors TJ. Learning enhances adult neurogenesis in the hippocampal formation. Nat Neurosci 1999; 2: 260-265
9. Johansson BB, Ohlsson A. Environmental, social interaction and physical activity as determinants of functional outcome after cerebral activity in the rat. Exp Nerol 1996; 139: 322-327
10. Kempermann G, Kuhn HG. More hippocampal neurons in adult mice living in an enriched environment. Nature 1997; 386: 493-495
11. Kim EH, Kim YJ, Lee HJ, Huh YB, Chung JH, Seo JC, Kang JE, Lee HJ, Yim SV, Kim CJ. Acupuncture increases cell proliferation in dentate gyrus after transient global ischemia in gerbils. Neurosci Lett 2001; 297: 21-24
12. Parent JM, Yu TW, Leibowitz RT, Geschwind DH, Sloviter RS, Lowenstein DH. Dentate granule cell neurogenesis is increased by seizures and contributes to aberrant network reorganization in the adult rat hippocampus. J Neurosci 1997; 17: 3727-3738
13. Trejo JL, Carro E, Torres-Aleman I. Circulating insulin-like growth factor I mediates exercise-induced increases in the number of new neurons in the adult. J Neurosci 2001; 21: 1628-1634
14. van Praag H, Christie BR, Sejnowski TJ, Gage FH. Running enhances neurogenesis, learning, and long-term potentiation in mice. Proc Natl Acad Sci USA 1999; 96: 13427-13431
15. van Praag H, Kempermann G, Gage FH. Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nat Neurosci 1999; 2: 266-270