Reversal of cisplatin and multidrug resistance by ribozyme-mediated glutathione suppression

Biochemical and Biophysical Research Communications

Volumn 286, Issue 2, 2001, Pages 406-413

  Nagata, Junko ^a   Kijima, Hiroshi ^a   Hatanaka, Hiroyuki ^a   Asai, Satomi ^a   Miyachi, Hayato ^a   Takagi, Atsushi ^a   Miwa, Takeshi ^a   Mine, Tetsuya ^a   Yamazaki, Hitoshi ^a   Nakamura, Masato ^a   Kondo, Takahito ^b   Scanlon, Kevin J ^c   Ueyama, Yoshito ^a  

^a TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b NAGASAKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c KECK GRADUATE INSTITUTE   (United States)

Author keywords

Glutathione (GSH); Multidrug resistance 1 (MDR1); Multidrug resistance associated protein (MRP); Ribozyme; Glutamylcysteine synthetase ( GCS)

Indexed keywords

ABC TRANSPORTER; ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; ETOPOSIDE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; MULTIDRUG RESISTANCE PROTEIN; RIBOZYME;

ARTICLE; CANCER CELL; CATALYSIS; CELLULAR IMMUNITY; COLON CANCER; DISULFIDE BOND; DNA REPAIR; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; MULTIDRUG RESISTANCE; OXIDATIVE STRESS; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

EID: 0034815968     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5399     Document Type: Article

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