Crystal structure of leukocyte Ig-like receptor LILRB4 (ILT3/LIR-5/CD85k): A myeloid inhibitory receptor involved in immune tolerance

Journal of Biological Chemistry

Volumn 286, Issue 20, 2011, Pages 18013-18025

  Cheng, Hao ^a,b   Mohammed, Fiyaz ^c   Nam, Gol ^a,b   Chen, Yong ^a,b   Qi, Jianxun ^a,e   Garner, Lee I ^c   Allen, Rachel L ^d   Yan, Jinghua ^a   Willcox, Benjamin E ^c   Gao, George F ^a,b,e  

^a INSTITUTE OF MICROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^d ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^e INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COVALENT BONDS; LIGANDS; SULFUR COMPOUNDS; T-CELLS;

BINDING GROUPS; DENDRITIC CELLS; DISULFIDE BONDS; IMMUNE RESPONSE; IMMUNE TOLERANCES; MOLECULAR MECHANISM; PROTEIN STABILITY; SURFACE PATCHES;

CRYSTAL STRUCTURE;

LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR B4; LYMPHOCYTE RECEPTOR; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; DISULFIDE BOND; HINGE REGION; IMMUNOLOGICAL TOLERANCE; IMMUNOREGULATION; LIGAND BINDING; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN STABILITY; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

EID: 79955780306     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.221028     Document Type: Article

References (66)

1. Janeway, C. A., Jr., and Medzhitov, R. (2002) Annu. Rev. Immunol. 20, 197-216
2. Prud'homme, G. J. (2004) J. Leukoc. Biol. 75, 586-599
3. Kawai, T., and Akira, S. (2006) Nat. Immunol. 7, 131-137
4. Nemazee, D. (2006) Nat. Rev. Immunol. 6, 728-740
5. Belkaid, Y., and Oldenhove, G. (2008) Immunity 29, 362-371
6. Sakaguchi, S., Yamaguchi, T., Nomura, T., and Ono, M. (2008) Cell 133, 775-787
7. Filaci, G., Fravega, M., Negrini, S., Procopio, F., Fenoglio, D., Rizzi, M., Brenci, S., Contini, P., Olive, D., Ghio, M., Setti, M., Accolla, R. S., Puppo, F., and Indiveri, F. (2004) Hum. Immunol. 65, 142-156
8. Liu, Z., Tugulea, S., Cortesini, R., and Suciu-Foca, N. (1998) Int. Immunol. 10, 775-783
9. Borges, L., Hsu, M. L., Fanger, N., Kubin, M., and Cosman, D. (1997) J. Immunol. 159, 5192-5196
10. Colonna, M., Navarro, F., Bellón, T., Llano, M., García, P., Samaridis, J., Angman, L., Cella, M., and López-Botet, M. (1997) J. Exp. Med. 186, 1809-1818
11. Cosman, D., Fanger, N., Borges, L., Kubin, M., Chin, W., Peterson, L., and Hsu, M. L. (1997) Immunity 7, 273-282
12. Samaridis, J., and Colonna, M. (1997) Eur. J. Immunol. 27, 660-665
13. Saverino, D., Fabbi, M., Ghiotto, F., Merlo, A., Bruno, S., Zarcone, D., Tenca, C., Tiso, M., Santoro, G., Anastasi, G., Cosman, D., Grossi, C. E., and Ciccone, E. (2000) J. Immunol. 165, 3742-3755
14. Lanier, L. L. (2005) Annu. Rev. Immunol. 23, 225-274
15. Volz, A., Wende, H., Laun, K., and Ziegler, A. (2001) Immunol. Rev. 181, 39-51
16. Colonna, M., Nakajima, H., and Cella, M. (2000) Semin. Immunol. 12, 121-127
17. Dietrich, J., Nakajima, H., and Colonna, M. (2000) Microbes Infect. 2, 323-329
18. Fanger, N. A., Cosman, D., Peterson, L., Braddy, S. C., Maliszewski, C. R., and Borges, L. (1998) Eur. J. Immunol. 28, 3423-3434
19. Morel, E., and Bellón, T. (2008) J. Immunol. 181, 2368-2381
20. Prod'homme, V., Griffin, C., Aicheler, R. J., Wang, E. C., McSharry, B. P., Rickards, C. R., Stanton, R. J., Borysiewicz, L. K., López-Botet, M., Wilkinson, G. W., and Tomasec, P. (2007) J. Immunol. 178, 4473-4481
21. Liu, W. R., Kim, J., Nwankwo, C., Ashworth, L. K., and Arm, J. P. (2000) Immunogenetics 51, 659-669
22. Young, N. T., Canavez, F., Uhrberg, M., Shum, B. P., and Parham, P. (2001) Immunogenetics 53, 270-278
23. Bellón, T., Kitzig, F., Sayós, J., and López-Botet, M. (2002) J. Immunol. 168, 3351-3359
24. Sayós, J., Martínez-Barriocanal, A., Kitzig, F., Bellón, T., and López-Botet, M. (2004) Biochem. Biophys. Res. Commun. 324, 640-647
25. Cao, W., Rosen, D. B., Ito, T., Bover, L., Bao, M., Watanabe, G., Yao, Z., Zhang, L., Lanier, L. L., and Liu, Y. J. (2006) J. Exp. Med. 203, 1399-1405
26. Nakajima, H., Samaridis, J., Angman, L., and Colonna, M. (1999) J. Immunol. 162, 5-8
27. Chapman, T. L., Heikeman, A. P., and Bjorkman, P. J. (1999) Immunity 11, 603-613
28. Chen, Y., Chu, F., Gao, F., Zhou, B., and Gao, G. F. (2007) Protein Expr. Purif. 56, 253-260
29. Chapman, T. L., Heikema, A. P., West, A. P., Jr., and Bjorkman, P. J. (2000) Immunity 13, 727-736
30. Shiroishi, M., Kuroki, K., Rasubala, L., Tsumoto, K., Kumagai, I., Kurimoto, E., Kato, K., Kohda, D., and Maenaka, K. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 16412-16417
31. Shiroishi, M., Kajikawa, M., Kuroki, K., Ose, T., Kohda, D., and Maenaka, K. (2006) J. Biol. Chem. 281, 19536-19544
32. Willcox, B. E., Thomas, L. M., and Bjorkman, P. J. (2003) Nat. Immunol. 4, 913-919
33. Willcox, B. E., Thomas, L. M., Chapman, T. L., Heikema, A. P., West, A. P., Jr., and Bjorkman, P. J. (2002) BMC Struct. Biol. 2, 6
34. Cao, W., Bover, L., Cho, M., Wen, X., Hanabuchi, S., Bao, M., Rosen, D. B., Wang, Y. H., Shaw, J. L., Du, Q., Li, C., Arai, N., Yao, Z., Lanier, L. L., and Liu, Y. J. (2009) J. Exp. Med. 206, 1603-1614
35. Cella, M., Döhring, C., Samaridis, J., Dessing, M., Brockhaus, M., Lanzavecchia, A., and Colonna, M. (1997) J. Exp. Med. 185, 1743-1751
36. Suciu-Foca, N., and Cortesini, R. (2007) Cell. Immunol. 248, 59-67
37. Suciu-Foca, N., Manavalan, J. S., Scotto, L., Kim-Schulze, S., Galluzzo, S., Naiyer, A. J., Fan, J., Vlad, G., and Cortesini, R. (2005) Int. Immunopharmacol. 5, 7-11
38. Vlad, G., Cortesini, R., and Suciu-Foca, N. (2008) Hum. Immunol. 69, 681-686
39. Chang, C. C., Ciubotariu, R., Manavalan, J. S., Yuan, J., Colovai, A. I., Piazza, F., Lederman, S., Colonna, M., Cortesini, R., Dalla-Favera, R., and Suciu-Foca, N. (2002) Nat. Immunol. 3, 237-243
40. Gleissner, C. A., Zastrow, A., Klingenberg, R., Kluger, M. S., Konstandin, M., Celik, S., Haemmerling, S., Shankar, V., Giese, T., Katus, H. A., and Dengler, T. J. (2007) Eur. J. Immunol. 37, 177-192
41. Manavalan, J. S., Kim-Schulze, S., Scotto, L., Naiyer, A. J., Vlad, G., Colombo, P. C., Marboe, C., Mancini, D., Cortesini, R., and Suciu-Foca, N. (2004) Int. Immunol. 16, 1055-1068
42. Manavalan, J. S., Rossi, P. C., Vlad, G., Piazza, F., Yarilina, A., Cortesini, R., Mancini, D., and Suciu-Foca, N. (2003) Transpl. Immunol. 11, 245-258
43. Svajger, U., Vidmar, A., and Jeras, M. (2008) Int. Immunopharmacol. 8, 997-1005
44. Kim-Schulze, S., Scotto, L., Vlad, G., Piazza, F., Lin, H., Liu, Z., Cortesini, R., and Suciu-Foca, N. (2006) J. Immunol. 176, 2790-2798
45. Suciu-Foca, N., Feirt, N., Zhang, Q. Y., Vlad, G., Liu, Z., Lin, H., Chang, C. C., Ho, E. K., Colovai, A. I., Kaufman, H., D'Agati, V. D., Thaker, H. M., Remotti, H., Galluzzo, S., Cinti, P., Rabitti, C., Allendorf, J., Chabot, J., Caricato, M., Coppola, R., Berloco, P., and Cortesini, R. (2007) J. Immunol. 178, 7432-7441
46. Borges, L., Kubin, M., and Kuhlman, T. (2003) Blood 101, 1484-1486
47. Garner, L. I., Salim, M., Mohammed, F., and Willcox, B. E. (2006) Protein. Expr. Purif. 47, 490-497
48. Gao, G. F., Tormo, J., Gerth, U. C., Wyer, J. R., McMichael, A. J., Stuart, D. I., Bell, J. I., Jones, E. Y., and Jakobsen, B. K. (1997) Nature 387, 630-634
49. Willcox, B. E., Gao, G. F., Wyer, J. R., O'Callaghan, C. A., Boulter, J. M., Jones, E. Y., van der Merwe, P. A., Bell, J. I., and Jakobsen, B. K. (1999) Protein Sci. 8, 2418-2423
50. Schuck, P. (2000) Biophys. J. 78, 1606-1619
51. Otwinowski, Z., and Minor, W. (1997) Methods Enzymol. 276, 307-326
52. Matthews, B.W. (1968) J. Mol. Biol. 33, 491-497
53. Vagin, A., and Teplyakov, A. (1997) J. Appl. Crystallogr. 30, 1022-1025
54. McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C., Read, R. J., (2007) J. Appl. Crystallogr. 40, 658-674
55. CCP4 (1994) Acta Crystallogr. D Biol. Crystallogr. 50, 760-763
56. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. D Biol. Crystallogr. 53, 240-255
57. Emsley, P., and Cowtan, K. (2004) Acta Crystallogr. D Biol. Crystallogr. 60, 2126-2132
58. Vaguine, A. A., Richelle, J., and Wodak, S. J. (1999) Acta Crystallogr.DBiol. Crystallogr. 55, 191-205
59. Fenn, T. D., Ringe, D., and Petsko, G. A. (2003) J. Appl. Crystallogr. 36, 944-947
60. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296
61. Chen, Y., Gao, F., Chu, F., Peng, H., Zong, L., Liu, Y., Tien, P., and Gao, G. F. (2009) J. Mol. Biol. 386, 841-853
62. Chen, Y., Liu, P., Gao, F., Cheng, H., Qi, J., and Gao, G. F. (2010) Protein Cell 1, 153-160
63. Saulquin, X., Gastinel, L. N., and Vivier, E. (2003) J. Exp. Med. 197, 933-938
64. Foster, C. E., Colonna, M., and Sun, P. D. (2003) J. Biol. Chem. 278, 46081-46086
65. Snyder, G. A., Brooks, A. G., and Sun, P. D. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 3864-3869
66. Porollo, A., and Meller, J. (2007) Proteins 66, 630-645