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Volumn 105, Issue 5, 2011, Pages 892-900

Urokinase-type plasminogen activator contributes to heterogeneity of macrophages at the border of damaged site during liver repair in mice

Author keywords

Liver repair; Macrophage accumulation; Macrophage activation; Macrophage heterogeneity; u PA

Indexed keywords

FIBRIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MANNOSE RECEPTOR; TISSUE PLASMINOGEN ACTIVATOR; UROKINASE; UROKINASE RECEPTOR;

EID: 79955754970     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH10-08-0516     Document Type: Article
Times cited : (14)

References (42)
  • 1
    • 0033517356 scopus 로고    scopus 로고
    • Cutaneous wound healing
    • Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med 1999; 341: 738-746.
    • (1999) N Engl J Med , vol.341 , pp. 738-746
    • Singer, A.J.1    Clark, R.A.2
  • 2
    • 79952512264 scopus 로고    scopus 로고
    • CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke
    • prepublished online
    • Mirabelli-Badenier M, Braunersreuther V, Viviani GL, et al. CC and CXC chemokines are pivotal mediators of cerebral injury in ischaemic stroke. Thromb Haemost 2011; 105: prepublished online.
    • (2011) Thromb Haemost , vol.105
    • Mirabelli-Badenier, M.1    Braunersreuther, V.2    Viviani, G.L.3
  • 3
    • 70350033399 scopus 로고    scopus 로고
    • Neutrophils launch monocyte extravasation by release of granule proteins
    • Soehnlein O, Zernecke A, Weber C. Neutrophils launch monocyte extravasation by release of granule proteins. Thromb Haemost 2009; 102: 198-205.
    • (2009) Thromb Haemost , vol.102 , pp. 198-205
    • Soehnlein, O.1    Zernecke, A.2    Weber, C.3
  • 4
    • 13744255589 scopus 로고    scopus 로고
    • Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair
    • Duffield JS, Forbes SJ, Constandinou CM, et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest 2005; 115: 56-65.
    • (2005) J Clin Invest , vol.115 , pp. 56-65
    • Duffield, J.S.1    Forbes, S.J.2    Constandinou, C.M.3
  • 5
    • 77955023275 scopus 로고    scopus 로고
    • Plasminogen is essential for granulation tissue formation during the recovery process after liver injury in mice
    • Kawao N, Nagai N, Ishida C, et al. Plasminogen is essential for granulation tissue formation during the recovery process after liver injury in mice. J Thromb Haemost 2010; 8: 1555-1566.
    • (2010) J Thromb Haemost , vol.8 , pp. 1555-1566
    • Kawao, N.1    Nagai, N.2    Ishida, C.3
  • 6
    • 4344706372 scopus 로고    scopus 로고
    • Functional plasticity of macrophages: Reversible adaptation to changing microenvironments
    • Stout RD, Suttles J. Functional plasticity of macrophages: reversible adaptation to changing microenvironments. J Leukoc Biol 2004; 76: 509-513.
    • (2004) J Leukoc Biol , vol.76 , pp. 509-513
    • Stout, R.D.1    Suttles, J.2
  • 7
    • 67049159513 scopus 로고    scopus 로고
    • Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes
    • Newby AC, George SJ, Ismail Y, et al. Vulnerable atherosclerotic plaque metalloproteinases and foam cell phenotypes. Thromb Haemost 2009; 101: 1006-1011.
    • (2009) Thromb Haemost , vol.101 , pp. 1006-1011
    • Newby, A.C.1    George, S.J.2    Ismail, Y.3
  • 8
    • 56749174940 scopus 로고    scopus 로고
    • Exploring the full spectrum of macrophage activation
    • Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol 2008; 8: 958-969.
    • (2008) Nat Rev Immunol , vol.8 , pp. 958-969
    • Mosser, D.M.1    Edwards, J.P.2
  • 9
    • 67649786938 scopus 로고    scopus 로고
    • Influence of the mannose receptor in host immune responses
    • Gazi U, Martinez-Pomares L. Influence of the mannose receptor in host immune responses. Immunobiology 2009; 214: 554-561.
    • (2009) Immunobiology , vol.214 , pp. 554-561
    • Gazi, U.1    Martinez-Pomares, L.2
  • 10
    • 0033046220 scopus 로고    scopus 로고
    • Mechanisms of phagocytosis in macrophages
    • Aderem A, Underhill DM. Mechanisms of phagocytosis in macrophages. Annu Rev Immunol 1999; 17: 593-623.
    • (1999) Annu Rev Immunol , vol.17 , pp. 593-623
    • Aderem, A.1    Underhill, D.M.2
  • 11
    • 16844384895 scopus 로고    scopus 로고
    • Structure and function of the plasminogen/plasmin system
    • Castellino FJ, Ploplis VA. Structure and function of the plasminogen/plasmin system. Thromb Haemost 2005; 93: 647-654.
    • (2005) Thromb Haemost , vol.93 , pp. 647-654
    • Castellino, F.J.1    Ploplis, V.A.2
  • 12
    • 0036906177 scopus 로고    scopus 로고
    • uPAR: A versatile signalling orchestrator
    • Blasi F, Carmeliet P. uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002; 3: 932-943.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 13
    • 38749101585 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke
    • Nagai N, Okada K, Kawao N, et al. Urokinase-type plasminogen activator receptor (uPAR) augments brain damage in a murine model of ischemic stroke. Neurosci Lett 2008; 432: 46-49.
    • (2008) Neurosci Lett , vol.432 , pp. 46-49
    • Nagai, N.1    Okada, K.2    Kawao, N.3
  • 14
    • 0033545965 scopus 로고    scopus 로고
    • Role of plasminogen system components in focal cerebral ischemic infarction: A gene targeting and gene transfer study in mice
    • Nagai N, De Mol M, Lijnen HR, et al. Role of plasminogen system components in focal cerebral ischemic infarction: a gene targeting and gene transfer study in mice. Circulation 1999; 99: 2440-2444.
    • (1999) Circulation , vol.99 , pp. 2440-2444
    • Nagai, N.1    de Mol, M.2    Lijnen, H.R.3
  • 15
    • 0033592863 scopus 로고    scopus 로고
    • Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver
    • Bezerra JA, Bugge TH, Melin-Aldana H, et al. Plasminogen deficiency leads to impaired remodeling after a toxic injury to the liver. Proc Natl Acad Sci USA 1999; 96: 15143-15148.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 15143-15148
    • Bezerra, J.A.1    Bugge, T.H.2    Melin-Aldana, H.3
  • 16
    • 0035101027 scopus 로고    scopus 로고
    • Plasminogen activators direct reorganization of the liver lobule after acute injury
    • Bezerra JA, Currier AR, Melin-Aldana H, et al. Plasminogen activators direct reorganization of the liver lobule after acute injury. Am J Pathol 2001; 158: 921-929.
    • (2001) Am J Pathol , vol.158 , pp. 921-929
    • Bezerra, J.A.1    Currier, A.R.2    Melin-Aldana, H.3
  • 17
    • 0035742094 scopus 로고    scopus 로고
    • Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury
    • Ng VL, Sabla GE, Melin-Aldana H, et al. Plasminogen deficiency results in poor clearance of non-fibrin matrix and persistent activation of hepatic stellate cells after an acute injury. J Hepatol 2001; 35: 781-789.
    • (2001) J Hepatol , vol.35 , pp. 781-789
    • Ng, V.L.1    Sabla, G.E.2    Melin-Aldana, H.3
  • 18
    • 0347320501 scopus 로고    scopus 로고
    • The regulation of liver regeneration by the plasmin/alpha 2-antiplasmin system
    • Okada K, Ueshima S, Imano M, et al. The regulation of liver regeneration by the plasmin/alpha 2-antiplasmin system. J Hepatol 2004; 40: 110-116.
    • (2004) J Hepatol , vol.40 , pp. 110-116
    • Okada, K.1    Ueshima, S.2    Imano, M.3
  • 19
    • 34249670317 scopus 로고    scopus 로고
    • Plasmin decreases the BH3-only protein BimEL via the ERK1/2 signaling pathway in hepatocytes
    • Kawao N, Okada K, Kawata S, et al. Plasmin decreases the BH3-only protein BimEL via the ERK1/2 signaling pathway in hepatocytes. Biochim Biophys Acta 2007; 1773: 718-727.
    • (2007) Biochim Biophys Acta , vol.1773 , pp. 718-727
    • Kawao, N.1    Okada, K.2    Kawata, S.3
  • 20
    • 58149115523 scopus 로고    scopus 로고
    • Binding of plasminogen to hepatocytes isolated from injured mice liver and nonparenchymal cell-dependent proliferation of hepatocytes
    • Okada K, Ueshima S, Kawao N, et al. Binding of plasminogen to hepatocytes isolated from injured mice liver and nonparenchymal cell-dependent proliferation of hepatocytes. Blood Coagul Fibrinolysis 2008; 19: 503-511.
    • (2008) Blood Coagul Fibrinolysis , vol.19 , pp. 503-511
    • Okada, K.1    Ueshima, S.2    Kawao, N.3
  • 21
    • 17744362678 scopus 로고    scopus 로고
    • Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: Impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis
    • Shimizu M, Hara A, Okuno M, et al. Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis. Hepatology 2001; 33: 569-576.
    • (2001) Hepatology , vol.33 , pp. 569-576
    • Shimizu, M.1    Hara, A.2    Okuno, M.3
  • 22
    • 28344449833 scopus 로고    scopus 로고
    • Macrophage activation switching: An asset for the resolution of inflammation
    • Porcheray F, Viaud S, Rimaniol AC, et al. Macrophage activation switching: an asset for the resolution of inflammation. Clin Exp Immunol 2005; 142: 481-489.
    • (2005) Clin Exp Immunol , vol.142 , pp. 481-489
    • Porcheray, F.1    Viaud, S.2    Rimaniol, A.C.3
  • 23
    • 77951667172 scopus 로고    scopus 로고
    • Role of plasminogen in macrophage accumulation during liver repair
    • Kawao N, Nagai N, Okada K, et al. Role of plasminogen in macrophage accumulation during liver repair. Thromb Res 2010; 125: e214-221.
    • (2010) Thromb Res , vol.125
    • Kawao, N.1    Nagai, N.2    Okada, K.3
  • 24
    • 0345118244 scopus 로고    scopus 로고
    • Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat
    • Kamanaka Y, Kawabata A, Matsuya H, et al. Effect of a potent iNOS inhibitor (ONO-1714) on acetaminophen-induced hepatotoxicity in the rat. Life Sci 2003; 74: 793-802.
    • (2003) Life Sci , vol.74 , pp. 793-802
    • Kamanaka, Y.1    Kawabata, A.2    Matsuya, H.3
  • 25
    • 77649341196 scopus 로고    scopus 로고
    • Initial brain lesion size affects the extent of subsequent pathophysiological responses
    • Nagai N, Kawao N, Okada K, et al. Initial brain lesion size affects the extent of subsequent pathophysiological responses. Brain Res 2010; 1322: 109-117.
    • (2010) Brain Res , vol.1322 , pp. 109-117
    • Nagai, N.1    Kawao, N.2    Okada, K.3
  • 26
    • 77952240691 scopus 로고    scopus 로고
    • Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis
    • Nagai N, Kawao N, Okada K, et al. Systemic transplantation of embryonic stem cells accelerates brain lesion decrease and angiogenesis. Neuroreport 2010; 21: 575-579.
    • (2010) Neuroreport , vol.21 , pp. 575-579
    • Nagai, N.1    Kawao, N.2    Okada, K.3
  • 27
    • 0025637040 scopus 로고
    • A new model for photochemically induced thrombosis in the inner ear microcirculation and the use of hearing loss as a measure for microcirculatory disorders
    • Umemura K, Kohno Y, Matsuno H, et al. A new model for photochemically induced thrombosis in the inner ear microcirculation and the use of hearing loss as a measure for microcirculatory disorders. Eur Arch Otorhinolaryngol 1990; 248: 105-108.
    • (1990) Eur Arch Otorhinolaryngol , vol.248 , pp. 105-108
    • Umemura, K.1    Kohno, Y.2    Matsuno, H.3
  • 28
    • 34447633015 scopus 로고    scopus 로고
    • Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice
    • Suzuki Y, Nagai N, Umemura K, et al. Stromelysin-1 (MMP-3) is critical for intracranial bleeding after t-PA treatment of stroke in mice. J Thromb Haemost 2007; 5: 1732-1739.
    • (2007) J Thromb Haemost , vol.5 , pp. 1732-1739
    • Suzuki, Y.1    Nagai, N.2    Umemura, K.3
  • 29
    • 70350462242 scopus 로고    scopus 로고
    • Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein
    • Suzuki Y, Nagai N, Yamakawa K, et al. Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein. Blood 2009; 114: 3352-3358.
    • (2009) Blood , vol.114 , pp. 3352-3358
    • Suzuki, Y.1    Nagai, N.2    Yamakawa, K.3
  • 30
    • 0028295979 scopus 로고
    • Physiological consequences of loss of plasminogen activator gene function in mice
    • Carmeliet P, Schoonjans L, Kieckens L, et al. Physiological consequences of loss of plasminogen activator gene function in mice. Nature 1994; 368: 419-424.
    • (1994) Nature , vol.368 , pp. 419-424
    • Carmeliet, P.1    Schoonjans, L.2    Kieckens, L.3
  • 31
    • 0030045209 scopus 로고    scopus 로고
    • Generation and characterization of urokinase receptor-deficient mice
    • Dewerchin M, Nuffelen AV, Wallays G, et al. Generation and characterization of urokinase receptor-deficient mice. J Clin Invest 1996; 97: 870-878.
    • (1996) J Clin Invest , vol.97 , pp. 870-878
    • Dewerchin, M.1    Nuffelen, A.V.2    Wallays, G.3
  • 32
    • 73549122173 scopus 로고    scopus 로고
    • Pkd2 dosage influences cellular repair responses following ischemia-reperfusion injury
    • Prasad S, McDaid JP, Tam FW, et al. Pkd2 dosage influences cellular repair responses following ischemia-reperfusion injury. Am J Pathol 2009; 175: 1493-1503.
    • (2009) Am J Pathol , vol.175 , pp. 1493-1503
    • Prasad, S.1    McDaid, J.P.2    Tam, F.W.3
  • 33
    • 34249915328 scopus 로고    scopus 로고
    • c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells
    • Hou Y, Okamoto C, Okada K, et al. c-Myc is essential for urokinase plasminogen activator expression on hypoxia-induced vascular smooth muscle cells. Cardiovasc Res 2007; 75: 186-194.
    • (2007) Cardiovasc Res , vol.75 , pp. 186-194
    • Hou, Y.1    Okamoto, C.2    Okada, K.3
  • 34
    • 33847108114 scopus 로고    scopus 로고
    • Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice
    • Sheehan JJ, Zhou C, Gravanis I, et al. Proteolytic activation of monocyte chemoattractant protein-1 by plasmin underlies excitotoxic neurodegeneration in mice. J Neurosci 2007; 27: 1738-1745.
    • (2007) J Neurosci , vol.27 , pp. 1738-1745
    • Sheehan, J.J.1    Zhou, C.2    Gravanis, I.3
  • 35
    • 51349089060 scopus 로고    scopus 로고
    • Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice
    • Gong Y, Hart E, Shchurin A, et al. Inflammatory macrophage migration requires MMP-9 activation by plasminogen in mice. J Clin Invest 2008; 118: 3012-3024.
    • (2008) J Clin Invest , vol.118 , pp. 3012-3024
    • Gong, Y.1    Hart, E.2    Shchurin, A.3
  • 36
    • 0037265240 scopus 로고    scopus 로고
    • Alternative activation of macrophages
    • Gordon S. Alternative activation of macrophages. Nat Rev Immunol 2003; 3: 23-35.
    • (2003) Nat Rev Immunol , vol.3 , pp. 23-35
    • Gordon, S.1
  • 37
    • 21244443731 scopus 로고    scopus 로고
    • Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences
    • Stout RD, Jiang C, Matta B, et al. Macrophages sequentially change their functional phenotype in response to changes in microenvironmental influences. J Immunol 2005; 175: 342-349.
    • (2005) J Immunol , vol.175 , pp. 342-349
    • Stout, R.D.1    Jiang, C.2    Matta, B.3
  • 38
    • 40449112315 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration
    • Bryer SC, Fantuzzi G, Van Rooijen N, et al. Urokinase-type plasminogen activator plays essential roles in macrophage chemotaxis and skeletal muscle regeneration. J Immunol 2008; 180: 1179-1188.
    • (2008) J Immunol , vol.180 , pp. 1179-1188
    • Bryer, S.C.1    Fantuzzi, G.2    van Rooijen, N.3
  • 39
    • 17444366177 scopus 로고    scopus 로고
    • S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors
    • Kwon M, MacLeod TJ, Zhang Y, et al. S100A10, annexin A2, and annexin a2 heterotetramer as candidate plasminogen receptors. Front Biosci 2005; 10: 300-325.
    • (2005) Front Biosci , vol.10 , pp. 300-325
    • Kwon, M.1    McLeod, T.J.2    Zhang, Y.3
  • 40
    • 36348985036 scopus 로고    scopus 로고
    • Histone H2B as a functionally important plasminogen receptor on macrophages
    • Das R, Burke T, Plow EF. Histone H2B as a functionally important plasminogen receptor on macrophages. Blood 2007; 110: 3763-3772.
    • (2007) Blood , vol.110 , pp. 3763-3772
    • Das, R.1    Burke, T.2    Plow, E.F.3
  • 41
    • 34249335018 scopus 로고    scopus 로고
    • Plasmin triggers cytokine induction in human monocyte-derived macrophages
    • Li Q, Laumonnier Y, Syrovets T, et al. Plasmin triggers cytokine induction in human monocyte-derived macrophages. Arterioscler Thromb Vasc Biol 2007; 27: 1383-1389.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 1383-1389
    • Li, Q.1    Laumonnier, Y.2    Syrovets, T.3
  • 42
    • 33645553587 scopus 로고    scopus 로고
    • Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation
    • Tarui T, Akakura N, Majumdar M, et al. Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation. Thromb Haemost 2006; 95: 524-534.
    • (2006) Thromb Haemost , vol.95 , pp. 524-534
    • Tarui, T.1    Akakura, N.2    Majumdar, M.3


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