In vitro effects of natural prenyloxycinnamic acids on human cytochrome P450 isozyme activity and expression

Phytomedicine

Volumn 18, Issue 7, 2011, Pages 586-591

  Genovese, S ^a   Epifano, F ^a   Curini, M ^b   Menger, D ^c   Zembruski, N C L ^c   Weiss, J ^c  

^a UNIVERSITY OF CHIETI   (Italy)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Cytochrome P450; Herb drug interaction; Induction; Inhibition; P glycoprotein; Prenyloxycinnamic acids; Prenyloxyphenylpropanoids

Indexed keywords

4' GERANYLOXY 4 COUMARIC ACID; 4' GERANYLOXY DIHYDRO 4 COUMARIC ACID; 4' GERANYLOXYFERULIC ACID; 4' ISOPENTENYLOXY 4 COUMARIC ACID; 4' ISOPENTENYLOXY DIHYDRO 4 COUMARIC ACID; BOROPINIC ACID; CALCEIN; CYTOCHROME P450 2B6; CYTOCHROME P450 2C19; CYTOCHROME P450 2C9; CYTOCHROME P450 2D6; CYTOCHROME P450 3A; CYTOCHROME P450 ISOENZYME; GLYCOPROTEIN P; MESSENGER RNA; NATURAL PRODUCT; PRENYLOXYCINNAMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; ENZYME METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; MEDICAL TECHNOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION;

CELL LINE, TUMOR; CINNAMATES; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; ENZYME INDUCTION; ENZYME INHIBITORS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; ISOENZYMES; P-GLYCOPROTEIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 79955685099     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2010.10.017     Document Type: Article

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