메뉴 건너뛰기




Volumn 28, Issue 5, 2011, Pages 345-367

Effects of selective serotonin reuptake inhibitors on platelet function: Mechanisms, clinical outcomes and implications for use in elderly patients

Author keywords

Antidepressants; Depression; Elderly; Haemorrhage; Platelets; Serotonin uptake inhibitors

Indexed keywords

CLOMIPRAMINE; NONSTEROID ANTIINFLAMMATORY AGENT; PAROXETINE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; VENLAFAXINE;

EID: 79955678784     PISSN: 1170229X     EISSN: 11791969     Source Type: Journal    
DOI: 10.2165/11589340-000000000-00000     Document Type: Review
Times cited : (162)

References (146)
  • 2
    • 0344844420 scopus 로고    scopus 로고
    • Epidemiology of late-life mental disorders
    • DOI 10.1016/S0749-0690(03)00042-9
    • Hybels CF, Blazer DG. Epidemiology of late-life mental disorders. Clin Geriatr Med 2003; 19: 663-96 (Pubitemid 37466819)
    • (2003) Clinics in Geriatric Medicine , vol.19 , Issue.4 , pp. 663-696
    • Hybels, C.F.1    Blazer, D.G.2
  • 3
    • 36549006511 scopus 로고    scopus 로고
    • Late-life depression
    • DOI 10.1056/NEJMcp073754
    • Unutzer J. Late-life depression. N Engl J Med 2006; 357: 2269-76 (Pubitemid 350190757)
    • (2007) New England Journal of Medicine , vol.357 , Issue.22 , pp. 2269-2276
    • Unutzer, J.1
  • 6
    • 44949099344 scopus 로고    scopus 로고
    • Tolerability of selective serotonin reuptake inhibitors: Issues relevant to the elderly
    • DOI 10.2165/00002512-200825060-00004
    • Draper B, Berman K. Tolerability of selective serotonin reuptake inhibitors: Issues relevant to the elderly. Drugs Aging 2008; 25: 501-19 (Pubitemid 351812258)
    • (2008) Drugs and Aging , vol.25 , Issue.6 , pp. 501-519
    • Draper, B.1    Berman, K.2
  • 7
    • 0345742559 scopus 로고    scopus 로고
    • Antidepressant-related deaths and antidepressant prescriptions in England and Wales, 1998-2000
    • DOI 10.1192/bjp.184.1.41
    • Cheeta S, Schifano F, Oyfeso A, et al. Antidepressantrelated deaths and antidepressant prescriptions in England and Wales, 1998-2000. Br J Psychiatry 2004; 184: 41-7 (Pubitemid 38085213)
    • (2004) British Journal of Psychiatry , vol.184 , Issue.JAN. , pp. 41-47
    • Cheeta, S.1    Schifano, F.2    Oyefeso, A.3    Webb, L.4    Ghodse, A.H.5
  • 8
    • 66249123109 scopus 로고    scopus 로고
    • Trends in antidepressant utilization from 2001 to 2004
    • Harman JS, EdlundMJ, Fortney JC. Trends in antidepressant utilization from 2001 to 2004. Psychiatr Serv 2009; 60: 611-6
    • (2009) Psychiatr Serv , vol.60 , pp. 611-616
    • Harman, J.S.1    Edlund, M.J.2    Fortney, J.C.3
  • 9
    • 55449126008 scopus 로고    scopus 로고
    • Trends in antidepressant prescriptions among the elderly in Alberta during 1997 to 2004
    • Newman SC, Schopflocher D. Trends in antidepressant prescriptions among the elderly in Alberta during 1997 to 2004. Can J Psychiatry 2008; 53: 704-7
    • (2008) Can J Psychiatry , vol.53 , pp. 704-707
    • Newman, S.C.1    Schopflocher, D.2
  • 10
    • 64549158645 scopus 로고    scopus 로고
    • The expanded biology of serotonin
    • Berger M, Gray JA, Roth BL. The expanded biology of serotonin. Annu Rev Med 2009; 60: 355-66
    • (2009) Annu Rev Med , vol.60 , pp. 355-366
    • Berger, M.1    Gray, J.A.2    Roth, B.L.3
  • 11
    • 0025269372 scopus 로고
    • Blood platelets as a model system for studying serotonergic dysfunction and effects of antidepressants
    • Lingjarde O. Blood platelets as a model system for studying serotonergic dysfunction and effects of antidepressants. Pharmacol Toxicol 1990; 66 Suppl. 3: 61-8
    • (1990) Pharmacol Toxicol , vol.66 , Issue.SUPPL. 3 , pp. 61-68
    • Lingjarde, O.1
  • 12
    • 0027212698 scopus 로고
    • Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter
    • Lesch KP, Wolozin BL, Murphy DL, et al. Primary structure of the human platelet serotonin uptake site: Identity with the brain serotonin transporter. J Neurochem 1993; 60: 2319-22 (Pubitemid 23148809)
    • (1993) Journal of Neurochemistry , vol.60 , Issue.6 , pp. 2319-2322
    • Lesch, K.-P.1    Wolozin, B.L.2    Murphy, D.L.3    Riederer, P.4
  • 13
    • 25444456933 scopus 로고    scopus 로고
    • Hypothesis: Antiplatelet effects of selective serotonin reuptake inhibitors cause clinical benefits on cardiovascular disease and increase risks of bleeding
    • DOI 10.1177/107424840501000303
    • Serebruany VL, O'Connor CM, Krishnan RR, et al. Hypothesis: Antiplatelet effects of selective serotonin reuptake inhibitors cause clinical benefits on cardiovascular disease and increase risks of bleeding. J Cardiovasc Pharmacol Ther 2005; 10: 163-4 (Pubitemid 41376973)
    • (2005) Journal of Cardiovascular Pharmacology and Therapeutics , vol.10 , Issue.3 , pp. 163-164
    • Serebruany, V.L.1    O'Connor, C.M.2    Krishnan, R.R.3    Hennekens, C.H.4
  • 14
    • 0030050198 scopus 로고    scopus 로고
    • Potential vascular and bleeding complications of treatment with selective serotonin reuptake inhibitors
    • Skop BP, Brown TM. Potential vascular and bleeding complications of treatment with selective serotonin reuptake inhibitors. Psychosomatics 1996; 37: 12-6 (Pubitemid 26021814)
    • (1996) Psychosomatics , vol.37 , Issue.1 , pp. 12-16
    • Skop, B.P.1    Brown, T.M.2
  • 15
    • 58149195303 scopus 로고    scopus 로고
    • Pharmacogenetics and the serotonin transporter in late-life depression
    • Gerretsen P, Pollock BG. Pharmacogenetics and the serotonin transporter in late-life depression. Expert Opin Drug Metab Toxicol 2008; 4: 1465-78
    • (2008) Expert Opin Drug Metab Toxicol , vol.4 , pp. 1465-1478
    • Gerretsen, P.1    Pollock, B.G.2
  • 16
    • 77149149768 scopus 로고    scopus 로고
    • Clinical implications of genetic variation in the serotonin transporter promoter region: A review
    • Luddington NS, Madadapu A, Husk M, et al. Clinical implications of genetic variation in the serotonin transporter promoter region: A review. J Clin Psychiatry 2009; 11: 93-102
    • (2009) J Clin Psychiatry , vol.11 , pp. 93-102
    • Luddington, N.S.1    Madadapu, A.2    Husk, M.3
  • 17
    • 41149146056 scopus 로고    scopus 로고
    • Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients
    • Lotrich FE, Pollock BG, Kirshner M, et al. Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response in geriatric patients. J Psychiatry Neurosci 2008; 33: 123-30 (Pubitemid 351441382)
    • (2008) Journal of Psychiatry and Neuroscience , vol.33 , Issue.2 , pp. 123-130
    • Lotrich, F.E.1    Pollock, B.G.2    Kirshner, M.3    Ferrell, R.F.4    Reynolds III, C.F.5
  • 18
    • 70449395449 scopus 로고    scopus 로고
    • Serotonergic mechanisms enhance platelet-mediated thrombogenicity
    • Galan AM, Lopez-Vilchez I, Diaz-Ricart M, et al. Serotonergic mechanisms enhance platelet-mediated thrombogenicity. Thromb Haemost 2009; 102: 511-9
    • (2009) Thromb Haemost , vol.102 , pp. 511-519
    • Galan, A.M.1    Lopez-Vilchez, I.2    Diaz-Ricart, M.3
  • 19
    • 33746218509 scopus 로고    scopus 로고
    • Platelet inhibition beyond conventional antiplatelet agents: Expanding role of angiotensin receptor blockers, statins and selective serotonin reuptake inhibitors
    • DOI 10.1111/j.1742-1241.2006.01063.x
    • Malinin AI, Ong S, Makarov LM, et al. Platelet inhibition beyond conventional antiplatelet agents: Expanding role of angiotensin receptor blockers, statins and selective serotonin reuptake inhibitors. Int J Clin Pract 2006; 60: 993-1002 (Pubitemid 44096587)
    • (2006) International Journal of Clinical Practice , vol.60 , Issue.8 , pp. 993-1002
    • Malinin, A.I.1    Ong, S.2    Makarov, L.M.3    Petukhova, E.Y.4    Serebruany, V.L.5
  • 20
    • 13244262832 scopus 로고    scopus 로고
    • Serotonin reuptake inhibitors and cardiovascular diseases: A platelet connection
    • DOI 10.1007/s00018-004-4262-1
    • Maurer-Spurej E. Serotonin reuptake inhibitors and cardiovascular diseases: A platelet connection. Cell Mol Life Sci 2005; 62: 159-70 (Pubitemid 40193040)
    • (2005) Cellular and Molecular Life Sciences , vol.62 , Issue.2 , pp. 159-170
    • Maurer-Spurej, E.1
  • 21
  • 22
    • 0033857466 scopus 로고    scopus 로고
    • Platelet reactivity in depressed patients treated with paroxetine: Preliminary findings
    • Musselman DL, Marzec UM, Manatunga A, et al. Platelet reactivity in depressed patients treated with paroxetine: Preliminary findings. Arch Gen Psychiatry 2000; 57: 875-82
    • (2000) Arch Gen Psychiatry , vol.57 , pp. 875-882
    • Musselman, D.L.1    Marzec, U.M.2    Manatunga, A.3
  • 25
    • 28444436585 scopus 로고    scopus 로고
    • Coated-platelets: An emerging component of the procoagulant response
    • DOI 10.1111/j.1538-7836.2005.01274.x
    • Dale GL. Coated-platelets: An emerging component of the procoagulant response. J Thromb Haemost 2005; 3: 2185-92 (Pubitemid 41727196)
    • (2005) Journal of Thrombosis and Haemostasis , vol.3 , Issue.10 , pp. 2185-2192
    • Dale, G.L.1
  • 26
    • 34548853423 scopus 로고    scopus 로고
    • Coated-platelet levels are influenced by smoking, aspirin, and selective serotonin reuptake inhibitors [2]
    • DOI 10.1111/j.1538-7836.2007.02691.x
    • Prodan CI, Joseph PM, Vincent AS, et al. Coated-platelet levels are influenced by smoking, aspirin and selective serotonin reuptake inhibitors. J Thromb Haemost 2007; 5: 2149-51 (Pubitemid 47450036)
    • (2007) Journal of Thrombosis and Haemostasis , vol.5 , Issue.10 , pp. 2149-2151
    • Prodan, C.I.1    Joseph, P.M.2    Vincent, A.S.3    Dale, G.L.4
  • 27
    • 0025041371 scopus 로고
    • 3H-imipramine binding, 5-HT uptake and 5-HT content in major depressive disorder
    • DOI 10.1016/0165-0327(90)90123-P
    • Wagner A, Montero D, Martensson B, et al. Effects of fluoxetine treatment of platelet 3H-imipramine binding, 5-HT uptake and 5-HT content in major depressive disorder. J Affect Dis 1990; 20: 101-13 (Pubitemid 20316952)
    • (1990) Journal of Affective Disorders , vol.20 , Issue.2 , pp. 101-113
    • Wagner, A.1    Montero, D.2    Martensson, B.3    Siwers, B.4    Asberg, M.5
  • 28
    • 0033736177 scopus 로고    scopus 로고
    • Paroxetine decreases platelet serotonin storage and platelet function in human beings
    • Hergovich N, Aigner M, Eichler HG, et al. Paroxetine decreases platelet serotonin storage and platelet function in human beings. Clin Pharmacol Ther 2000; 68: 435-42
    • (2000) Clin Pharmacol Ther , vol.68 , pp. 435-442
    • Hergovich, N.1    Aigner, M.2    Eichler, H.G.3
  • 29
    • 0033803685 scopus 로고    scopus 로고
    • Reduction of platelet serotonin content in depressed patients treated with either paroxetine or desipramine
    • Javors MA, Houston JP, Tekell JL, et al. Reduction of platelet serotonin content in depressed patients treated with either paroxetine or desipramine. Int J Neuropsychopharmacol 2000; 3: 229-35
    • (2000) Int J Neuropsychopharmacol , vol.3 , pp. 229-235
    • Javors, M.A.1    Houston, J.P.2    Tekell, J.L.3
  • 30
    • 0026098627 scopus 로고
    • Effects of clomipramine treatment on cerebrospinal fluid monoamine metabolites and platelet 3H-imipramine binding and serotonin uptake and concentration in major depressive disorder
    • Martensson B, Wagner A, Beck O, et al. Effects of clomipramine treatment on cerebrospinal fluid monoamine metabolites and platelet 3H-imipramine binding and serotonin uptake and concentration in major depressive disorder. Acta Psychiatr Scand 1991; 83: 125-33
    • (1991) Acta Psychiatr Scand , vol.83 , pp. 125-133
    • Martensson, B.1    Wagner, A.2    Beck, O.3
  • 31
    • 0026643057 scopus 로고
    • A doubleblind, placebo controlled study of trazodone in patients with obsessive-compulsive disorder
    • Pigott TA, L'Hereux F, Rubenstein CS, et al. A doubleblind, placebo controlled study of trazodone in patients with obsessive-compulsive disorder. J Clin Psychopharmacol 1992; 12: 156-62
    • (1992) J Clin Psychopharmacol , vol.12 , pp. 156-162
    • Pigott, T.A.1    L'Hereux, F.2    Rubenstein, C.S.3
  • 34
    • 0031565115 scopus 로고    scopus 로고
    • Pharmacological profile of antidepressants and related compounds at human monoamine transporters
    • DOI 10.1016/S0014-2999(97)01393-9, PII S0014299997013939
    • Tatsumi M, Groshan K, Blakely RD, et al. Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol 1997; 340: 249-58 (Pubitemid 28022649)
    • (1997) European Journal of Pharmacology , vol.340 , Issue.2-3 , pp. 249-258
    • Tatsumi, M.1    Groshan, K.2    Blakely, R.D.3    Richelson, E.4
  • 35
    • 0028893021 scopus 로고
    • Fluoxetine and hemostatic function: A pilot study
    • Berk M, Jacobson BF, Hurly E. Fluoxetine and hemostatic function: A pilot study. J Clin Psychiatry 1995; 56: 14-6
    • (1995) J Clin Psychiatry , vol.56 , pp. 14-16
    • Berk, M.1    Jacobson, B.F.2    Hurly, E.3
  • 36
    • 0026566884 scopus 로고
    • Abnormal platelet aggregation associated with fluoxetine therapy
    • Alderman CP, Moritz CK, Ben-Tovim DL. Abnormal platelet aggregation associated with fluoxetine therapy. Ann Pharmacother 1992; 26: 1517-9
    • (1992) Ann Pharmacother , vol.26 , pp. 1517-1519
    • Alderman, C.P.1    Moritz, C.K.2    Ben-Tovim, D.L.3
  • 38
    • 56749175269 scopus 로고    scopus 로고
    • Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism
    • Abdelmalik N, Ruhé HG, Barwari K, et al. Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism. J Thromb Haemost 2008; 6: 2168-74
    • (2008) J Thromb Haemost , vol.6 , pp. 2168-2174
    • Abdelmalik, N.1    Ruhé, H.G.2    Barwari, K.3
  • 39
    • 59949103451 scopus 로고    scopus 로고
    • Evidence why doseescalation of paroxetine in major depressive disorder is not effective: A 6-week, randomized-controlled trial with assessment of serotonin transporter occupancy
    • Ruhe HG, Booij J, Weert HC, et al. Evidence why doseescalation of paroxetine in major depressive disorder is not effective: A 6-week, randomized-controlled trial with assessment of serotonin transporter occupancy. Neuropsychopharmacology 2009; 34: 999-1010
    • (2009) Neuropsychopharmacology , vol.34 , pp. 999-1010
    • Ruhe, H.G.1    Booij, J.2    Weert, H.C.3
  • 42
    • 0025762245 scopus 로고
    • Fluoxetine and bleeding in obsessive-compulsive disorder [letter]
    • Yaryura-Tobias JA, Kirschen H, Ninan P, et al. Fluoxetine and bleeding in obsessive-compulsive disorder [letter]. Am J Psychiatry 1991; 148: 949
    • (1991) Am J Psychiatry , vol.148 , pp. 949
    • Yaryura-Tobias, J.A.1    Kirschen, H.2    Ninan, P.3
  • 44
    • 0030281668 scopus 로고    scopus 로고
    • Fluvoxamine-associated bleeding
    • Leung M, Shore R. Fluvoxamine-associated bleeding. Can J Psychiatry 1996; 41: 604-5
    • (1996) Can J Psychiatry , vol.41 , pp. 604-605
    • Leung, M.1    Shore, R.2
  • 45
    • 0029976067 scopus 로고    scopus 로고
    • Prolonged bleeding time in a patient treated with sertraline [5]
    • Calhoun JW, Calhoun DD. Prolonged bleeding time in a patient treated with sertraline [letter]. Am J Psychiatry 1996; 153: 443 (Pubitemid 26074730)
    • (1996) American Journal of Psychiatry , vol.153 , Issue.3 , pp. 443
    • Calhoun, J.W.1    Calhoun, D.D.2
  • 46
    • 0031068125 scopus 로고    scopus 로고
    • Venlafaxine and ecchymosis [letter]
    • Khon S, Labbate LA. Venlafaxine and ecchymosis [letter]. Can J Psychiatry 1997; 42: 91
    • (1997) Can J Psychiatry , vol.42 , pp. 91
    • Khon, S.1    Labbate, L.A.2
  • 49
    • 0033598594 scopus 로고    scopus 로고
    • Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: Population based case-control study
    • De Abajo FJ, García Rodríguez LA, Montero D. Association between selective serotonin reuptake inhibitors and upper gastrointestinal bleeding: Population based case-control study. BMJ 1999; 319: 1106-9 (Pubitemid 29494721)
    • (1999) British Medical Journal , vol.319 , Issue.7217 , pp. 1106-1109
    • De Abajo, F.J.1    Garcia Rodriguez, L.A.2    Montero, D.3
  • 50
    • 85044702342 scopus 로고    scopus 로고
    • SSRIs are not more likely than other drugs to cause such bleeding
    • Dunn NR, Pearce GL, Shakir SAW. SSRIs are not more likely than other drugs to cause such bleeding. BMJ 2000; 320: 1405-6
    • (2000) BMJ , vol.320 , pp. 1405-1406
    • Dunn, N.R.1    Pearce, G.L.2    Shakir, S.A.W.3
  • 51
    • 0035934609 scopus 로고    scopus 로고
    • Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: Retrospective cohort study
    • Van Walraven C, Mamdami MM, Wells PS, et al. Inhibition of serotonin reuptake by antidepressants and upper gastrointestinal bleeding in elderly patients: Retrospective cohort study. BMJ 2001; 323: 1-6
    • (2001) BMJ , vol.323 , pp. 1-6
    • Van Walraven, C.1    Mamdami, M.M.2    Wells, P.S.3
  • 52
    • 13744265417 scopus 로고    scopus 로고
    • Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding a population-based cohort study
    • DOI 10.1001/archinte.163.1.59
    • Dalton SO, Johansen C, Mellemkjaer L, et al. Use of selective serotonin reuptake inhibitors and risk of upper gastrointestinal tract bleeding: A population-based cohort study. Arch Intern Med 2003; 165: 59-64 (Pubitemid 36091601)
    • (2003) Archives of Internal Medicine , vol.163 , Issue.1 , pp. 59-64
    • Dalton, S.O.1    Johansen, C.2    Mellemkjaer, L.3    Norgard, B.4    Sorensen, H.T.5    Olsen, J.H.6
  • 54
    • 33645046396 scopus 로고    scopus 로고
    • Increased use of selective serotonin reuptake inhibitors in patients admitted with acute gastrointestinal hemorrhage: A multicentre retrospective analysis
    • Wessinger S, Kaplan M, Choi L, et al. Increased use of selective serotonin reuptake inhibitors in patients admitted with acute gastrointestinal hemorrhage: A multicentre retrospective analysis. Aliment Pharmacol Ther 2006; 23: 937-44
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 937-944
    • Wessinger, S.1    Kaplan, M.2    Choi, L.3
  • 56
    • 33947167258 scopus 로고    scopus 로고
    • Risk of serious upper gastrointestinal events with concurrent use of NSAIDs and SSRIs: A case-control study in the general population
    • DOI 10.1007/s00228-007-0263-y
    • Helin-Salmivaara A, Huttunen T, Grönroos JM, et al. Risk of serious upper gastrointestinal events with concurrent use of NSAIDs and SSRIs: A case-control study in the general population. Eur J Clin Pharmacol 2007; 63: 403-8 (Pubitemid 46399132)
    • (2007) European Journal of Clinical Pharmacology , vol.63 , Issue.4 , pp. 403-408
    • Helin-Salmivaara, A.1    Huttunen, T.2    Gronroos, J.M.3    Klaukka, T.4    Huupponen, R.5
  • 59
    • 46849119197 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy : Interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents
    • DOI 10.1001/archpsyc.65.7.795
    • De Abajo FJ, García-Rodríguez LA. Risk of upper gastrointestinal tract bleeding associated with selective serotonin reuptake inhibitors and venlafaxine therapy: Interaction with nonsteroidal anti-inflammatory drugs and effect of acid-suppressing agents. Arch Gen Psychiatry 2008; 65: 795-803 (Pubitemid 351957705)
    • (2008) Archives of General Psychiatry , vol.65 , Issue.7 , pp. 795-803
    • De Abajo, F.J.1    Garcia-Rodriguez, L.A.2
  • 60
    • 62649157946 scopus 로고    scopus 로고
    • Antidepressant drug prescription and risk of abnormal bleeding: A casecontrol study
    • Barbui C, Andretta M, De Vitis G, et al. Antidepressant drug prescription and risk of abnormal bleeding: A casecontrol study. J Clin Psychopharmacol 2009; 29: 33-8
    • (2009) J Clin Psychopharmacol , vol.29 , pp. 33-38
    • Barbui, C.1    Andretta, M.2    De Vitis, G.3
  • 61
    • 66949114992 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors are associated with a modest increase in the risk of upper gastrointestinal bleeding
    • Targownik LE, Bolton JM, Metge CJ, et al. Selective serotonin reuptake inhibitors are associated with a modest increase in the risk of upper gastrointestinal bleeding. Am J Gastroenterol 2009; 104: 1475-82
    • (2009) Am J Gastroenterol , vol.104 , pp. 1475-1482
    • Targownik, L.E.1    Bolton, J.M.2    Metge, C.J.3
  • 62
    • 70849119641 scopus 로고    scopus 로고
    • An association between selective serotonin reuptake inhibitor use and serious upper gastrointestinal bleeding
    • Dall M, Schaffalitzky de Muckadell OB, Lassen AT, et al. An association between selective serotonin reuptake inhibitor use and serious upper gastrointestinal bleeding. Clin Gastroenterol Hepatol 2009; 7: 1314-21
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 1314-1321
    • Dall, M.1    Schaffalitzky De Muckadell, O.B.2    Lassen, A.T.3
  • 64
    • 79955691097 scopus 로고    scopus 로고
    • Aggravation by selective serotonin re-uptake inhibitors (SSRIs) of antral lesions induced by indomethacin in rats: Effects of antisecretory and mucosal protective drugs [abstract]
    • Tanaka A, Takahira Y, Izumi N, et al. Aggravation by selective serotonin re-uptake inhibitors (SSRIs) of antral lesions induced by indomethacin in rats: Effects of antisecretory and mucosal protective drugs [abstract]. Gastroenterology 2005: M2063
    • (2005) Gastroenterology
    • Tanaka, A.1    Takahira, Y.2    Izumi, N.3
  • 65
    • 46449124525 scopus 로고    scopus 로고
    • The coadministration of paroxetine and low-dose aspirin synergistically enhances gastric ulcerogenic risk in rats
    • DOI 10.1248/bpb.31.1371
    • Yamaguchi T, Hidaka N, Suemaru K, et al. The coadministration of paroxetine and low-dose aspirin synergistically enhances gastric ulcerogenic risk in rats. Biol Pharm Bull 2008; 31: 1371-5 (Pubitemid 351930649)
    • (2008) Biological and Pharmaceutical Bulletin , vol.31 , Issue.7 , pp. 1371-1375
    • Yamaguchi, T.1    Hidaka, N.2    Suemaru, K.3    Araki, H.4
  • 66
    • 74049134798 scopus 로고    scopus 로고
    • High prevalence of gastroduodenal mucosa injury in patients taking selective serotonin reuptake inhibitors [letter]
    • Yamamoto T, Abe K, Hattori K, et al. High prevalence of gastroduodenal mucosa injury in patients taking selective serotonin reuptake inhibitors [letter]. Digestive Endoscopy 2010; 22: 77
    • (2010) Digestive Endoscopy , vol.22 , pp. 77
    • Yamamoto, T.1    Abe, K.2    Hattori, K.3
  • 67
    • 78449289498 scopus 로고    scopus 로고
    • There is an association between selective serotonin reuptake inhibitor use and uncomplicated peptic ulcers: A population- based case-control study
    • Dall M, Schaffalitzky de Muckadell OB, Lassen AT, et al. There is an association between selective serotonin reuptake inhibitor use and uncomplicated peptic ulcers: A population- based case-control study. Aliment Pharmacol Ther 2010; 32: 1383-91
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1383-1391
    • Dall, M.1    Schaffalitzky De Muckadell, O.B.2    Lassen, A.T.3
  • 68
    • 0343472105 scopus 로고    scopus 로고
    • Individual nonsteroidal antiinflammatory drugs and other risk factors for upper gastrointestinal bleeding and perforation
    • Gutthann SP, García Rodríguez LA, Raiford DS. Individual nonsteroidal antiinflammatory drugs and other risk factors for upper gastrointestinal bleeding and perforation. Epidemiology 1997; 8: 18-24 (Pubitemid 27014216)
    • (1997) Epidemiology , vol.8 , Issue.1 , pp. 18-24
    • Gutthann, S.P.1    Garcia Rodriguez, L.A.2    Raiford, D.S.3
  • 69
    • 0036140865 scopus 로고    scopus 로고
    • Incidence of serious upper gastrointestinal bleeding/perforation in the general population: Review of epidemiologic studies
    • DOI 10.1016/S0895-4356(01)00461-9, PII S0895435601004619
    • Hernández-Díaz S, García Rodríguez LA. Incidence of serious upper gastrointestinal bleeding/perforation in the general population: Review of epidemiologic studies. J Clin Epidemiol 2002; 55: 157-63 (Pubitemid 34051529)
    • (2002) Journal of Clinical Epidemiology , vol.55 , Issue.2 , pp. 157-163
    • Hernandez-Diaz, S.1    Rodriguez, L.A.G.2
  • 72
    • 40949144117 scopus 로고    scopus 로고
    • The risk of postpartum hemorrhage with selective serotonin reuptake inhibitors and other antidepressants
    • DOI 10.1097/JCP.0b013e318166c52e, PII 0000471420080400000017
    • Salkeld E, Ferris LE, Juurlink DN. The risk of postpartum hemorrhage with selective serotonin reuptake inhibitors and other antidepressants. J Clin Psychopharmacol 2008; 28: 230-4 (Pubitemid 351417131)
    • (2008) Journal of Clinical Psychopharmacology , vol.28 , Issue.2 , pp. 230-234
    • Salkeld, E.1    Ferris, L.E.2    Juurlink, D.N.3
  • 73
    • 65449144335 scopus 로고    scopus 로고
    • Safety of selective serotonin reuptake inhibitor in adults undergoing coronary artery bypass grafting
    • Kim DH, Daskalakis C, Whellan DJ, et al. Safety of selective serotonin reuptake inhibitor in adults undergoing coronary artery bypass grafting. Am J Cardiol 2009; 103: 1391-5
    • (2009) Am J Cardiol , vol.103 , pp. 1391-1395
    • Kim, D.H.1    Daskalakis, C.2    Whellan, D.J.3
  • 74
    • 77953849975 scopus 로고    scopus 로고
    • Safety of selective serotonin reuptake inhibitor use prior to coronary artery bypass grafting
    • Xiong GL, Jiang W, Clare RM, et al. Safety of selective serotonin reuptake inhibitor use prior to coronary artery bypass grafting. Clin Cardiol 2010; 33: E94-8
    • (2010) Clin Cardiol , vol.33
    • Xiong, G.L.1    Jiang, W.2    Clare, R.M.3
  • 75
    • 77249131280 scopus 로고    scopus 로고
    • Use of selective serotonin reuptake inhibitors and risk of reoperation due to post-surgical bleeding in breast cance patients: A Danish population-based cohort study
    • Gärtner R, Cronin-Fenton D, Hundborg HH, et al. Use of selective serotonin reuptake inhibitors and risk of reoperation due to post-surgical bleeding in breast cance patients: A Danish population-based cohort study. BMC Surg 2010; 10: 3
    • (2010) BMC Surg , vol.10 , pp. 3
    • Gärtner, R.1    Cronin-Fenton, D.2    Hundborg, H.H.3
  • 76
    • 77649091663 scopus 로고    scopus 로고
    • Use of serotonergic antidepressants and bleeding risk in orthopedic patients
    • Van Haelst IM, Egberts TC, Doodeman HJ, et al. Use of serotonergic antidepressants and bleeding risk in orthopedic patients. Anesthesiology 2010; 112: 631-6
    • (2010) Anesthesiology , vol.112 , pp. 631-636
    • Van Haelst, I.M.1    Egberts, T.C.2    Doodeman, H.J.3
  • 77
    • 0001867030 scopus 로고
    • Beutler E, Lichtman MA, Coller BS, et al., editors. William's hematology. 5th ed New York: McGraw-Hill
    • Ware JA, Coller BS. Platelet morphology, biochemistry, and function. In: Beutler E, Lichtman MA, Coller BS, et al., editors. William's hematology. 5th ed. New York: McGraw-Hill, 1995: 1161-93
    • (1995) Platelet Morphology, Biochemistry, and Function , pp. 1161-1193
    • Ware, J.A.1    Coller, B.S.2
  • 82
    • 73149121141 scopus 로고    scopus 로고
    • Antidepressant use and risk of incident cardiovascular morbidity and mortality among postmenopausal women in the Women'sHealth Initiative study
    • Smoller JW, Allison M, Cochrane BB, et al. Antidepressant use and risk of incident cardiovascular morbidity and mortality among postmenopausal women in the Women'sHealth Initiative study. Arch Intern Med 2009; 169: 2128-39
    • (2009) Arch Intern Med , vol.169 , pp. 2128-2139
    • Smoller, J.W.1    Allison, M.2    Cochrane, B.B.3
  • 84
    • 38749112521 scopus 로고    scopus 로고
    • Increased bleeding risk with concurrent use of selective serotonin reuptake inhibitors and coumarins
    • DOI 10.1001/archinternmed.2007.32
    • Schalekamp T, Klungel OH, Souverein PC, et al. Increased bleeding risk with concurrent use of selective serotonin reuptake inhibitors and coumarins. Arch Intern Med 2008; 168: 180-5 (Pubitemid 351185885)
    • (2008) Archives of Internal Medicine , vol.168 , Issue.2 , pp. 180-185
    • Schalekamp, T.1    Klungel, O.H.2    Souverein, P.C.3    De Boer, A.4
  • 85
    • 67649389950 scopus 로고    scopus 로고
    • Risk of clinically relevant bleeding in warfarin-treated patients: Influence of SSRI treatment
    • Wallerstedt SM, Gleerup H, Sundström A, et al. Risk of clinically relevant bleeding in warfarin-treated patients: Influence of SSRI treatment. Pharmacoepidemiol Drug Saf 2009; 18: 412-6
    • (2009) Pharmacoepidemiol Drug Saf , vol.18 , pp. 412-416
    • Wallerstedt, S.M.1    Gleerup, H.2    Sundström, A.3
  • 86
    • 72949087810 scopus 로고    scopus 로고
    • The effect of drug interactions on bleeding risk associated with warfarin therapy in hospitalized patients
    • Hauta-Aho M, Tirkkonen T, Vahlberg T, et al. The effect of drug interactions on bleeding risk associated with warfarin therapy in hospitalized patients. Ann Med 2009; 41: 619-28
    • (2009) Ann Med , vol.41 , pp. 619-628
    • Hauta-Aho, M.1    Tirkkonen, T.2    Vahlberg, T.3
  • 87
    • 0035026947 scopus 로고    scopus 로고
    • Is there an association between selective serotonin reuptake inhibitors and risk of abnormal bleeding? Results from a cohort study based on prescription event monitoring in England
    • DOI 10.1007/s002280100263
    • Layton D, Clark DWJ, Pearce GL, et al. Is there an association between selective serotonin reuptake inhibitors and risk of abnormal bleeding? Results from a cohort study based on prescription event monitoring in England. Eur J Clin Pharmacol 2001; 57: 167-76 (Pubitemid 32449139)
    • (2001) European Journal of Clinical Pharmacology , vol.57 , Issue.2 , pp. 167-176
    • Layton, D.1    Clark, D.W.J.2    Pearce, G.L.3    Shakir, S.A.W.4
  • 90
    • 33846417966 scopus 로고    scopus 로고
    • Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: A meta-analysis of randomized trials
    • DOI 10.1001/archinte.167.2.117
    • Dentali F, Douketis JD, Lim W, et al. Combined aspirin: Oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease - a meta-analysis of randomized trials. Arch Intern Med 2007; 167: 117-24 (Pubitemid 46148058)
    • (2007) Archives of Internal Medicine , vol.167 , Issue.2 , pp. 117-124
    • Dentali, F.1    Douketis, J.D.2    Lim, W.3    Crowther, M.4
  • 91
    • 34548314463 scopus 로고    scopus 로고
    • Drug-drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding
    • DOI 10.1503/cmaj.070186
    • Delaney JA, Opatrny L, Brophy JM, et al. Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ 2007; 177: 347-51 (Pubitemid 47339530)
    • (2007) Canadian Medical Association Journal , vol.177 , Issue.4 , pp. 347-351
    • Delaney, J.A.1    Opatrny, L.2    Brophy, J.M.3    Suissa, S.4
  • 92
    • 0037346611 scopus 로고    scopus 로고
    • Do depressive symptoms increase the risk for the onset of coronary disease? A systematic quantitative review
    • DOI 10.1097/01.PSY.0000058371.50240.E3
    • Wulsin LR, Singal BM. Do depressive symptoms increase the risk for the onset of coronary disease? A systematic quantitative review. Psychosom Med 2003; 65: 201-10 (Pubitemid 36359331)
    • (2003) Psychosomatic Medicine , vol.65 , Issue.2 , pp. 201-210
    • Wulsin, L.R.1    Singal, B.M.2
  • 93
    • 34247269178 scopus 로고    scopus 로고
    • Depression and cardiovascular comorbidity
    • Glassman AH. Depression and cardiovascular comorbidity. Dialogues Clin Neurosci 2007; 9: 9-17 (Pubitemid 46607127)
    • (2007) Dialogues in Clinical Neuroscience , vol.9 , Issue.1 , pp. 9-17
    • Glassman, A.H.1
  • 95
    • 77955014011 scopus 로고    scopus 로고
    • INTERSTROKE investigators Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study
    • O'Donnell MJ, Xavier D, Liu L, et al., INTERSTROKE investigators. Risk factors for ischaemic and intracerebral haemorrhagic stroke in 22 countries (the INTERSTROKE study): A case-control study. Lancet 2010; 376: 112-23
    • (2010) Lancet , vol.376 , pp. 112-123
    • O'Donnell, M.J.1    Xavier, D.2    Liu, L.3
  • 96
    • 13244258520 scopus 로고    scopus 로고
    • Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease
    • DOI 10.1016/j.atherosclerosis.2004.08.035, PII S002191500400468X
    • Bonnet F, Irving K, Terra JL, et al. Anxiety and depression are associated with unhealthy lifestyle in patients at risk of cardiovascular disease. Atherosclerosis 2005; 178: 339-44 (Pubitemid 40193449)
    • (2005) Atherosclerosis , vol.178 , Issue.2 , pp. 339-344
    • Bonnet, F.1    Irving, K.2    Terra, J.-L.3    Nony, P.4    Berthezene, F.5    Moulin, P.6
  • 97
    • 19344364140 scopus 로고    scopus 로고
    • Depression, alterations in platelet function, and ischemic heart disease
    • DOI 10.1097/01.psy.0000164227.63647.d9
    • Bruce EC, Musselman DL. Depression, alterations in platelet function, and ischemic heart disease. Psychosom Med 2005; 67 Suppl. 1: S34-6 (Pubitemid 40721030)
    • (2005) Psychosomatic Medicine , vol.67 , Issue.SUPPL. 1
    • Bruce, E.C.1    Musselman, D.L.2
  • 98
    • 67649398929 scopus 로고    scopus 로고
    • Cardiovascular abnormalities in patients with major depressive disorder autonomic mechanisms and implications for treatment
    • Brown AD, Barton DA, Lambert GW. Cardiovascular abnormalities in patients with major depressive disorder autonomic mechanisms and implications for treatment. CNS Drugs 2009; 23: 583-602
    • (2009) CNS Drugs , vol.23 , pp. 583-602
    • Brown, A.D.1    Barton, D.A.2    Lambert, G.W.3
  • 101
    • 77249092687 scopus 로고    scopus 로고
    • Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules
    • Lekakis J, Ikonomidis I, Papoutsi Z, et al. Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules. Int J Cardiol 2010; 139: 150-8
    • (2010) Int J Cardiol , vol.139 , pp. 150-158
    • Lekakis, J.1    Ikonomidis, I.2    Papoutsi, Z.3
  • 104
    • 0033977733 scopus 로고    scopus 로고
    • Excess risk of myocardial infarction in patients treated with antidepressant medications: Association with use of tricyclic agents
    • DOI 10.1016/S0002-9343(99)00301-0, PII S0002934399003010
    • Cohen HW, Gibson G, Alderman MH. Excess risk of myocardial infarction in patients treated with antidepressant medications: Association with use of tricyclic agents. Am J Med 2000; 108: 2-8 (Pubitemid 30058271)
    • (2000) American Journal of Medicine , vol.108 , Issue.1 , pp. 2-8
    • Cohen, H.W.1    Gibson, G.2    Alderman, M.H.3
  • 105
    • 0035899867 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors and myocardial infarction
    • Sauer WH, Berlin JA, Kimmel SE. Selective serotonin reuptake inhibitors and myocardial infarction. Circulation 2001; 104: 1894-8 (Pubitemid 32983230)
    • (2001) Circulation , vol.104 , Issue.16 , pp. 1894-1898
    • Sauer, W.H.1    Berlin, J.A.2    Kimmel, S.E.3
  • 106
    • 0034819851 scopus 로고    scopus 로고
    • Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarction
    • DOI 10.1046/j.0306-5251.2001.01426.x
    • Meier CR, Schlienger RG, Jick H. Use of selective serotonin reuptake inhibitors and risk of developing first-time acute myocardial infarction. Br J Clin Pharmacol 2001; 52: 179-84 (Pubitemid 32863076)
    • (2001) British Journal of Clinical Pharmacology , vol.52 , Issue.2 , pp. 179-184
    • Meier, C.R.1    Schlienger, R.G.2    Jick, H.3
  • 108
    • 0038503196 scopus 로고    scopus 로고
    • Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction
    • DOI 10.1161/01.CIR.0000079172.43229.CD
    • Sauer WH, Berlin JA, Kimmel SE. Effect of antidepressants and their relative affinity for the serotonin transporter on the risk of myocardial infarction. Circulation 2003; 108: 32-6 (Pubitemid 36859016)
    • (2003) Circulation , vol.108 , Issue.1 , pp. 32-36
    • Sauer, W.H.1    Berlin, J.A.2    Kimmel, S.E.3
  • 109
    • 10644231925 scopus 로고    scopus 로고
    • Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction
    • DOI 10.2165/00002018-200427140-00006
    • Schlienger RG, Fischer LM, Jick H, et al. Current use of selective serotonin reuptake inhibitors and risk of acute myocardial infarction. Drug Saf 2004; 27: 1157-65 (Pubitemid 39647855)
    • (2004) Drug Safety , vol.27 , Issue.14 , pp. 1157-1165
    • Schlienger, R.G.1    Fischer, L.M.2    Jick, H.3    Meier, C.R.4
  • 110
    • 8344242876 scopus 로고    scopus 로고
    • Antidepressants and risk of first-time hospitalization for myocardial infarction: A population-based case-control study
    • DOI 10.1016/j.amjmed.2004.06.027, PII S0002934304005194
    • Monster TB, Johnsen SP, Olsen ML, et al. Antidepressants and risk of first-time hospitalization for myocardial infarction: A population-based case-control study. Am J Med 2004 Nov 15; 117(10): 732-7 (Pubitemid 39482526)
    • (2004) American Journal of Medicine , vol.117 , Issue.10 , pp. 732-737
    • Monster, T.B.M.1    Johnsen, S.P.2    Olsen, M.L.3    McLaughlin, J.K.4    Sorensen, H.T.5
  • 111
    • 15844407976 scopus 로고    scopus 로고
    • General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction
    • DOI 10.1136/hrt.2004.037457
    • Tata LJ, West J, Smith C, et al. General population based study of the impact of tricyclic and selective serotonin reuptake inhibitor antidepressants on the risk of acute myocardial infarction. Heart 2005; 91: 465-71 (Pubitemid 40432771)
    • (2005) Heart , vol.91 , Issue.4 , pp. 465-471
    • Tata, L.J.1    West, J.2    Smith, C.3    Farrington, P.4    Card, T.5    Smeeth, L.6    Hubbard, R.7
  • 112
    • 17644373415 scopus 로고    scopus 로고
    • Past use of selective serotonin reuptake inhibitors and the risk of cerebrovascular events in the elderly
    • DOI 10.1097/00004850-200505000-00008
    • Barbui C, Percudani M, Fortino I, et al. Past use of selective serotonin reuptake inhibitors and the risk of cerebrovascular events in the elderly. Int Clin Psychopharmacol 2005; 20: 169-71 (Pubitemid 40571516)
    • (2005) International Clinical Psychopharmacology , vol.20 , Issue.3 , pp. 169-171
    • Barbui, C.1    Percudani, M.2    Fortino, I.3    Tansella, M.4    Petrovich, L.5
  • 113
    • 39049090630 scopus 로고    scopus 로고
    • Risk of cerebrovascular events associated with antidepressant use in patients with depression: A population-based, nested case-control study
    • DOI 10.1345/aph.1K369
    • Chen Y, Guo JJ, Li H, et al. Risk of cerebrovascular events associated with antidepressant use in patients with depression: A population-based, nested case-control study. Ann Pharmacother 2008; 42: 177-84 (Pubitemid 351238564)
    • (2008) Annals of Pharmacotherapy , vol.42 , Issue.2 , pp. 177-184
    • Chen, Y.1    Guo, J.J.2    Li, H.3    Wulsin, L.4    Patel, N.C.5
  • 114
    • 77952373634 scopus 로고    scopus 로고
    • Risk of ischemic stroke associated with antidepressant drug use in elderly persons
    • Trifirò G, Dieleman J, Sen EF, et al. Risk of ischemic stroke associated with antidepressant drug use in elderly persons. J Clin Psychopharmacol 2010; 30: 252-8
    • (2010) J Clin Psychopharmacol , vol.30 , pp. 252-258
    • Trifirò, G.1    Dieleman, J.2    Sen, E.F.3
  • 115
    • 33845284249 scopus 로고    scopus 로고
    • Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort
    • DOI 10.1001/archpsyc.63.12.1358
    • Tiihonen J, Lonnqvist J, Wahlbeck K, et al. Antidepressants and the risk of suicide, attempted suicide, and overall mortality in a nationwide cohort. Arch Gen Psychiatry 2006; 63: 1358-67 (Pubitemid 44878519)
    • (2006) Archives of General Psychiatry , vol.63 , Issue.12 , pp. 1358-1367
    • Tiihonen, J.1    Lonnqvist, J.2    Wahlbeck, K.3    Klaukka, T.4    Tanskanen, A.5    Haukka, J.6
  • 116
    • 0141609605 scopus 로고    scopus 로고
    • Epidemiology of comorbid coronary artery disease and depression
    • DOI 10.1016/S0006-3223(03)00587-0
    • Rudisch B, Nemeroff CB. Epidemiology of comorbid coronary artery disease and depression. Biol Psychiatry 2003; 54: 227-40 (Pubitemid 37267853)
    • (2003) Biological Psychiatry , vol.54 , Issue.3 , pp. 227-240
    • Rudisch, B.1    Nemeroff, C.B.2
  • 118
    • 9244240975 scopus 로고    scopus 로고
    • Depression as a risk factor for mortality in patients with coronary heart disease: A meta-analysis
    • DOI 10.1097/01.psy.0000146332.53619.b2
    • Barth J, Schumacher M, Herrmann-Lingen C. Depression as a risk factor for mortality in patients with coronary heart disease: A meta-analysis. Psychosom Med 2004; 66: 802-13 (Pubitemid 39552862)
    • (2004) Psychosomatic Medicine , vol.66 , Issue.6 , pp. 802-813
    • Barth, J.1    Schumacher, M.2    Herrmann-Lingen, C.3
  • 120
    • 0037022928 scopus 로고    scopus 로고
    • Five-year risk of cardiac mortality in relation to initial severity and one-year changes in depression symptoms after myocardial infarction
    • DOI 10.1161/hc0902.104707
    • Lesperance F, Frasure-Smith N, Talajic M, et al. Five-year risk of cardiac mortality in relation to initial severity and one-year changes in depression symptoms after myocardial infarction. Circulation 2002; 105: 1049-53 (Pubitemid 34212612)
    • (2002) Circulation , vol.105 , Issue.9 , pp. 1049-1053
    • Lesperance, F.1    Frasure-Smith, N.2    Talajic, M.3    Bourassa, M.G.4
  • 123
    • 33745661633 scopus 로고    scopus 로고
    • Depression and cardiovascular disease: Healing the broken-hearted
    • DOI 10.1001/jama.295.24.2874
    • Whooley MA. Depression and cardiovascular disease: Healing the broken-hearted. JAMA 2006; 295: 2874-81 (Pubitemid 43974185)
    • (2006) Journal of the American Medical Association , vol.295 , Issue.24 , pp. 2874-2881
    • Whooley, M.A.1
  • 124
    • 57049134256 scopus 로고    scopus 로고
    • Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease
    • Whooley MA, de Jonge P, Vittinghoff E, et al. Depressive symptoms, health behaviors, and risk of cardiovascular events in patients with coronary heart disease. JAMA 2008; 300: 2379-88
    • (2008) JAMA , vol.300 , pp. 2379-2388
    • Whooley, M.A.1    De Jonge, P.2    Vittinghoff, E.3
  • 125
    • 78751507147 scopus 로고    scopus 로고
    • The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes
    • Huffman JC, Celano CM, Januzzi JL. The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes. Neuropsychiatr Dis Treat 2010; 6: 123-36
    • (2010) Neuropsychiatr Dis Treat , vol.6 , pp. 123-136
    • Huffman, J.C.1    Celano, C.M.2    Januzzi, J.L.3
  • 126
    • 34247250831 scopus 로고    scopus 로고
    • Common genetic factors for depression and cardiovascular disease
    • Brondy B. Common genetic factors for depression and cardiovascular disease. Dialogues Clin Neurosci 2007; 9: 19-28
    • (2007) Dialogues Clin Neurosci , vol.9 , pp. 19-28
    • Brondy, B.1
  • 127
    • 0141609186 scopus 로고    scopus 로고
    • Poststroke depression: Prevalence, diagnosis, treatment, and disease progression
    • DOI 10.1016/S0006-3223(03)00423-2
    • Robinson RG. Poststroke depression: Prevalence, diagnosis, treatment, and disease progression. Biol Psychiatry 2003; 54: 376-87 (Pubitemid 37267864)
    • (2003) Biological Psychiatry , vol.54 , Issue.3 , pp. 376-387
    • Robinson, R.G.1
  • 128
    • 0035075994 scopus 로고    scopus 로고
    • Prospective study of depressive symptoms and risk of stroke among Japanese
    • Ohira T, Iso H, Satoh S, et al. Prospective study of depressive symptoms and risk of stroke among Japanese. Stroke 2001; 32: 903-8
    • (2001) Stroke , vol.32 , pp. 903-908
    • Ohira, T.1    Iso, H.2    Satoh, S.3
  • 130
    • 34648834440 scopus 로고    scopus 로고
    • Depression and coronary heart disease: More pieces of the puzzle
    • DOI 10.1176/appi.ajp.2007.07071053
    • Carney RM, Freeland KE. Depression and coronary heart disease: More pieces of the puzzle. Am J Psychiatry 2007; 164: 1307-9 (Pubitemid 47461126)
    • (2007) American Journal of Psychiatry , vol.164 , Issue.9 , pp. 1307-1309
    • Carney, R.M.1    Freedland, K.E.2
  • 131
    • 34249873268 scopus 로고    scopus 로고
    • Does treating depression improve survival after acute coronary syndrome?
    • Carney RM, Freeland KE. Does treating depression improve survival after acute coronary syndrome? Br J Psychiatry 2007; 190: 467-8
    • (2007) Br J Psychiatry , vol.190 , pp. 467-468
    • Carney, R.M.1    Freeland, K.E.2
  • 133
    • 0038507402 scopus 로고    scopus 로고
    • Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial
    • Berkman LF, Blumenthal J, Burg M, et al. Effects of treating depression and low perceived social support on clinical events after myocardial infarction: The Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA 2003; 289: 3106-16
    • (2003) JAMA , vol.289 , pp. 3106-3116
    • Berkman, L.F.1    Blumenthal, J.2    Burg, M.3
  • 137
    • 65449169318 scopus 로고    scopus 로고
    • Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD)
    • Hansen BH, Hanash JA, Rasmussen A, et al. Rationale, design and methodology of a double-blind, randomized, placebo-controlled study of escitalopram in prevention of Depression in Acute Coronary Syndrome (DECARD). Trials 2009; 10: 20
    • (2009) Trials , vol.10 , pp. 20
    • Hansen, B.H.1    Hanash, J.A.2    Rasmussen, A.3
  • 138
    • 0037406908 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients
    • DOI 10.1176/appi.psy.44.3.216
    • Rasmussen A, Lunde M, Poulsen DL, et al. A double-blind, placebo-controlled study of sertraline in the prevention of depression in stroke patients. Psychosomatics 2003; 44: 216-21 (Pubitemid 36514728)
    • (2003) Psychosomatics , vol.44 , Issue.3 , pp. 216-221
    • Rasmussen, A.1    Lunde, M.2    Poulsen, D.L.3    Sorensen, K.4    Qvitzau, S.5    Bech, P.6
  • 140
    • 66249146404 scopus 로고    scopus 로고
    • Mirtazapine: A review of its use in major depression and other psychiatric disorders
    • Croom KF, Perry CM, Plosker GL. Mirtazapine: A review of its use in major depression and other psychiatric disorders. CNS Drugs 2009; 23: 427-52
    • (2009) CNS Drugs , vol.23 , pp. 427-452
    • Croom, K.F.1    Perry, C.M.2    Plosker, G.L.3
  • 141
    • 33846501306 scopus 로고    scopus 로고
    • Adverse cardiovascular events in antidepressant trials involving high-risk patients: A systematic review of randomized trials
    • Swenson JR, Doucette S, Fergusson D. Adverse cardiovascular events in antidepressant trials involving high-risk patients: A systematic review of randomized trials. Can J Psychiatry 2006; 51: 923-9 (Pubitemid 46354056)
    • (2006) Canadian Journal of Psychiatry , vol.51 , Issue.14 , pp. 923-929
    • Swenson, J.R.1    Doucette, S.2    Fergusson, D.3
  • 142
    • 78650088616 scopus 로고    scopus 로고
    • Selective serotonin reuptake inhibitors provide significant lower rehospitalization rates in patients recovering from acute coronary syndromes: Evidence from a meta-analysis
    • Mazza M, Lotrionte M, Biondi-Zoccai G, et al. Selective serotonin reuptake inhibitors provide significant lower rehospitalization rates in patients recovering from acute coronary syndromes: Evidence from a meta-analysis. J Psychopharmacol 2010; 24: 1785-92
    • (2010) J Psychopharmacol , vol.24 , pp. 1785-1792
    • Mazza, M.1    Lotrionte, M.2    Biondi-Zoccai, G.3
  • 144
    • 72049100088 scopus 로고    scopus 로고
    • Psychotropic medication use and risk of adverse cardiovascular events in women with suspected coronary artery disease: Outcomes from the Women's Ischemia Syndrome Evaluation (WISE) study
    • Krantz DS, Whittaker KS, Francis JL, et al. Psychotropic medication use and risk of adverse cardiovascular events in women with suspected coronary artery disease: Outcomes from the Women's Ischemia Syndrome Evaluation (WISE) study. Heart 2009; 95: 1901-6
    • (2009) Heart , vol.95 , pp. 1901-1906
    • Krantz, D.S.1    Whittaker, K.S.2    Francis, J.L.3
  • 145
    • 77952942723 scopus 로고    scopus 로고
    • Variability among nonsteroidal anti-inflammatory drugs in risk of upper gastrointestinal bleeding
    • Massó González EL, Patrignani P, Tacconelli S, et al. Variability among nonsteroidal anti-inflammatory drugs in risk of upper gastrointestinal bleeding. Arthritis Rheum 2010; 62: 1592-601
    • (2010) Arthritis Rheum , vol.62 , pp. 1592-1601
    • Massó González, E.L.1    Patrignani, P.2    Tacconelli, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.