메뉴 건너뛰기




Volumn 167, Issue 2, 2007, Pages 117-124

Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: A meta-analysis of randomized trials

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT;

EID: 33846417966     PISSN: 00039926     EISSN: 15383679     Source Type: Journal    
DOI: 10.1001/archinte.167.2.117     Document Type: Review
Times cited : (178)

References (54)
  • 1
    • 4644371108 scopus 로고    scopus 로고
    • Salem DN, Stein PD, Al-Ahmad A, et al. Antithrombotic therapy in valvular heart disease-native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3)(suppl):457S- 482S.
    • Salem DN, Stein PD, Al-Ahmad A, et al. Antithrombotic therapy in valvular heart disease-native and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3)(suppl):457S- 482S.
  • 2
    • 33646152752 scopus 로고    scopus 로고
    • Comparison of bleeding in patients with nonvalvular atrial fibrillation treated with ximelagatran or warfarin: Assessment of incidence, case fatality rate, time course, anatomic sites and risk factors for bleeding
    • Douketis JD, Arneklev K, Goldhaber SZ, Spandorfer J, Halperin F, Horrow J. Comparison of bleeding in patients with nonvalvular atrial fibrillation treated with ximelagatran or warfarin: assessment of incidence, case fatality rate, time course, anatomic sites and risk factors for bleeding. Arch Intern Med. 2006;166:853-859.
    • (2006) Arch Intern Med , vol.166 , pp. 853-859
    • Douketis, J.D.1    Arneklev, K.2    Goldhaber, S.Z.3    Spandorfer, J.4    Halperin, F.5    Horrow, J.6
  • 3
    • 0035854054 scopus 로고    scopus 로고
    • Validation of clinical classification schemes for predicting stroke: Results from the National Registry of Atrial Fibrillation
    • Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285:2864-2870.
    • (2001) JAMA , vol.285 , pp. 2864-2870
    • Gage, B.F.1    Waterman, A.D.2    Shannon, W.3    Boechler, M.4    Rich, M.W.5    Radford, M.J.6
  • 5
    • 0028244264 scopus 로고    scopus 로고
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med. 1994;154:1449-1457.
    • Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials. Arch Intern Med. 1994;154:1449-1457.
  • 6
    • 0348109325 scopus 로고    scopus 로고
    • The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: A meta-analysis
    • Vink R, Kraaijenhagen RA, Hutten BA, et al. The optimal intensity of vitamin K antagonists in patients with mechanical heart valves: a meta-analysis. J Am Coll Cardiol. 2003;42:2042-2048.
    • (2003) J Am Coll Cardiol , vol.42 , pp. 2042-2048
    • Vink, R.1    Kraaijenhagen, R.A.2    Hutten, B.A.3
  • 8
    • 4744355196 scopus 로고    scopus 로고
    • Combined anticoagulant-antiplatelet use and major bleeding events in elderly atrial fibrillation patients
    • Shireman TI, Howard PA, Kresowik TF, Ellerbeck EF. Combined anticoagulant-antiplatelet use and major bleeding events in elderly atrial fibrillation patients. Stroke. 2004;35:2362-2367.
    • (2004) Stroke , vol.35 , pp. 2362-2367
    • Shireman, T.I.1    Howard, P.A.2    Kresowik, T.F.3    Ellerbeck, E.F.4
  • 9
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • Jadad AR, Moore RA, Carroll D, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials. 1996; 17:1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 10
    • 0034152834 scopus 로고    scopus 로고
    • Assessing allocation concealment and blinding in randomized controlled trials: Why bother?
    • Schulz KF. Assessing allocation concealment and blinding in randomized controlled trials: why bother? ACP J Club. 2000;132:A11-A12.
    • (2000) ACP J Club , vol.132
    • Schulz, K.F.1
  • 11
    • 23044505564 scopus 로고    scopus 로고
    • Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients
    • Schulman S, Kearon C; Subcommittee on Control of Anticoagulation of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in non-surgical patients. J Thromb Haemost. 2005;3:692-694.
    • (2005) J Thromb Haemost , vol.3 , pp. 692-694
    • Schulman, S.1    Kearon, C.2
  • 12
    • 9644259108 scopus 로고    scopus 로고
    • Evidence-Based Medicine Teaching Tips Working Group. Tips for learners of evidence-based medicine: 3: measures of observer variability (kappa statistic)
    • McGinn T, Wyer PC, Newman TB, Keitz S, Leipzig R, For GG; Evidence-Based Medicine Teaching Tips Working Group. Tips for learners of evidence-based medicine: 3: measures of observer variability (kappa statistic). CMAJ. 2004;171:1369-1373.
    • (2004) CMAJ , vol.171 , pp. 1369-1373
    • McGinn, T.1    Wyer, P.C.2    Newman, T.B.3    Keitz, S.4    Leipzig, R.5    For, G.G.6
  • 13
    • 0023250550 scopus 로고
    • Misinterpretation and misuse of the kappa statistic
    • Maclure M, Willett WC. Misinterpretation and misuse of the kappa statistic. Am J Epidemiol. 1987; 126:161-169.
    • (1987) Am J Epidemiol , vol.126 , pp. 161-169
    • Maclure, M.1    Willett, W.C.2
  • 14
    • 84959801619 scopus 로고
    • Statistical aspects of the analysis of data from retrospective studies of disease
    • Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst. 1959;22:719-748.
    • (1959) J Natl Cancer Inst , vol.22 , pp. 719-748
    • Mantel, N.1    Haenszel, W.2
  • 17
    • 0030922816 scopus 로고    scopus 로고
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-634.
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315:629-634.
  • 19
    • 0037072090 scopus 로고    scopus 로고
    • Antithrombotics in the Secondary Prevention of Events in Coronary Thrombosis-2 (ASPECT-2) Research Group. Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): A randomised controlled trial
    • Van Es RF, Jonker JJ, Verheugt FW, Deckers JW, Grobbee DE; Antithrombotics in the Secondary Prevention of Events in Coronary Thrombosis-2 (ASPECT-2) Research Group. Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trial. Lancet. 2002; 360:109-113.
    • (2002) Lancet , vol.360 , pp. 109-113
    • Van Es, R.F.1    Jonker, J.J.2    Verheugt, F.W.3    Deckers, J.W.4    Grobbee, D.E.5
  • 20
    • 5644295138 scopus 로고    scopus 로고
    • NASPEAF Investigators. Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: A randomized multicenter study
    • Perez-Gomez F, Alegria E, Berjon J, et al; NASPEAF Investigators. Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: a randomized multicenter study. J Am Coll Cardiol. 2004;44:1557-1566.
    • (2004) J Am Coll Cardiol , vol.44 , pp. 1557-1566
    • Perez-Gomez, F.1    Alegria, E.2    Berjon, J.3
  • 21
    • 0038001477 scopus 로고    scopus 로고
    • Thrombosis prevention trial: Compliance with warfarin treatment and investigation of a retained effect
    • Rudnicka AR, Ashby D, Brennan P, Meade T. Thrombosis prevention trial: compliance with warfarin treatment and investigation of a retained effect. Arch Intern Med. 2003;163:1454-1460.
    • (2003) Arch Intern Med , vol.163 , pp. 1454-1460
    • Rudnicka, A.R.1    Ashby, D.2    Brennan, P.3    Meade, T.4
  • 22
    • 0344084428 scopus 로고    scopus 로고
    • Effect of low-dose aspirin on the international normalized ratio variability in patients with mechanical heart valve prostheses
    • Casais P, Meschengieser SS, Sanchez Luceros AG, Bermejo EI, Lazzari MA. Effect of low-dose aspirin on the international normalized ratio variability in patients with mechanical heart valve prostheses. Pathophysiol Haemost Thromb. 2002; 32:155-157.
    • (2002) Pathophysiol Haemost Thromb , vol.32 , pp. 155-157
    • Casais, P.1    Meschengieser, S.S.2    Sanchez Luceros, A.G.3    Bermejo, E.I.4    Lazzari, M.A.5
  • 23
    • 0037156466 scopus 로고    scopus 로고
    • Antithrombotic treatment and the incidence of angina pectoris
    • Knottenbelt C, Brennan PJ, Meade TW. Antithrombotic treatment and the incidence of angina pectoris. Arch Intern Med. 2002;162:881-886.
    • (2002) Arch Intern Med , vol.162 , pp. 881-886
    • Knottenbelt, C.1    Brennan, P.J.2    Meade, T.W.3
  • 24
    • 0035954275 scopus 로고    scopus 로고
    • Aspirin, warfarin, or the combination for secondary prevention of coronary events in patients with acute coronary syndromes and prior coronary artery bypass surgery
    • Huynh T, Theroux P, Bogaty P, et al. Aspirin, warfarin, or the combination for secondary prevention of coronary events in patients with acute coronary syndromes and prior coronary artery bypass surgery. Circulation. 2001;103:3069-3074.
    • (2001) Circulation , vol.103 , pp. 3069-3074
    • Huynh, T.1    Theroux, P.2    Bogaty, P.3
  • 25
    • 0013229317 scopus 로고    scopus 로고
    • Anticoagulant (fluindione)-aspirin combination n patients with high-risk atrial fibrillation: A randomized trial (Fluindione, Fibrillation Auriculaire, Aspirin et Contraste Spontane; FFAACS)
    • Lechat P, Lardoux H, Mallet A, et al. Anticoagulant (fluindione)-aspirin combination n patients with high-risk atrial fibrillation: a randomized trial (Fluindione, Fibrillation Auriculaire, Aspirin et Contraste Spontane; FFAACS). Cerebrovasc Dis. 2001; 12:245-252.
    • (2001) Cerebrovasc Dis , vol.12 , pp. 245-252
    • Lechat, P.1    Lardoux, H.2    Mallet, A.3
  • 26
    • 0034460484 scopus 로고    scopus 로고
    • Effects of warfarin, aspirin and the two combined, on mortality and thromboembolic morbidity after myocardial infarction: The WARIS-II (Warfarin-Aspirin Reinfarction Study) design
    • Hurlen M, Smith P, Arnesen H. Effects of warfarin, aspirin and the two combined, on mortality and thromboembolic morbidity after myocardial infarction: the WARIS-II (Warfarin-Aspirin Reinfarction Study) design. Scand Cardiovasc J. 2000; 34:168-171.
    • (2000) Scand Cardiovasc J , vol.34 , pp. 168-171
    • Hurlen, M.1    Smith, P.2    Arnesen, H.3
  • 27
    • 0034162093 scopus 로고    scopus 로고
    • Early and long-term (one-year) effects of the association of aspirin and oral anticoagulant on thrombi and morbidity after replacement of the mitral valve with the St Jude medical prosthesis
    • Laffort P, Roudaut R, Roques X, et al. Early and long-term (one-year) effects of the association of aspirin and oral anticoagulant on thrombi and morbidity after replacement of the mitral valve with the St Jude medical prosthesis. J Am Coll Cardiol. 2000;35:739-746.
    • (2000) J Am Coll Cardiol , vol.35 , pp. 739-746
    • Laffort, P.1    Roudaut, R.2    Roques, X.3
  • 28
    • 0034484457 scopus 로고    scopus 로고
    • Investigateurs de FFAACS. Study of combined anticoagulant (fluindione)-aspirin therapy in patients with atrial fibrillation at high risk for thromboembolic complications: A randomized trial (FFAACS) [article in French]
    • Lechat P, Lardoux H, Mallet A, et al; Investigateurs de FFAACS. Study of combined anticoagulant (fluindione)-aspirin therapy in patients with atrial fibrillation at high risk for thromboembolic complications: a randomized trial (FFAACS) [article in French]. Therapie. 2000;55:681-689.
    • (2000) Therapie , vol.55 , pp. 681-689
    • Lechat, P.1    Lardoux, H.2    Mallet, A.3
  • 29
    • 0034037203 scopus 로고    scopus 로고
    • Effects of fixed low-dose warfarin, aspirin-warfarin combination therapy, and dose-adjusted warfarin on thrombogenesis in chronic atrial fibrillation
    • Li-Saw-Hee FL, Blann AD, Lip GY. Effects of fixed low-dose warfarin, aspirin-warfarin combination therapy, and dose-adjusted warfarin on thrombogenesis in chronic atrial fibrillation. Stroke. 2000; 31:828-833.
    • (2000) Stroke , vol.31 , pp. 828-833
    • Li-Saw-Hee, F.L.1    Blann, A.D.2    Lip, G.Y.3
  • 30
    • 0032945720 scopus 로고    scopus 로고
    • Aortic plaque in atrial fibrillation: Prevalence, predictors, and thromboembolic implications
    • Blackshear JL, Pearce LA, Hart RG, et al. Aortic plaque in atrial fibrillation: prevalence, predictors, and thromboembolic implications. Stroke. 1999;30:834-840.
    • (1999) Stroke , vol.30 , pp. 834-840
    • Blackshear, J.L.1    Pearce, L.A.2    Hart, R.G.3
  • 31
    • 0033612559 scopus 로고    scopus 로고
    • Bleeding during warfarin and aspirin therapy in patients with atrial fibrillation
    • Gullov AL, Gade Koefoed B, Petersen P. Bleeding during warfarin and aspirin therapy in patients with atrial fibrillation. Arch Intern Med. 1999;159: 1322-1328.
    • (1999) Arch Intern Med , vol.159 , pp. 1322-1328
    • Gullov, A.L.1    Gade Koefoed, B.2    Petersen, P.3
  • 32
    • 0032562005 scopus 로고    scopus 로고
    • Thrombosis prevention trial: Randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk
    • The Medical Research Council's General Practice Research Framework
    • The Medical Research Council's General Practice Research Framework. Thrombosis prevention trial: randomised trial of low-intensity oral anticoagulation with warfarin and low-dose aspirin in the primary prevention of ischaemic heart disease in men at increased risk. Lancet. 1998; 351:233-241.
    • (1998) Lancet , vol.351 , pp. 233-241
  • 33
    • 0031852543 scopus 로고    scopus 로고
    • Fixed minidose warfarin and aspirin alone and in combination vs adjusted-dose warfarin for stroke prevention in atrial fibrillation: Second Copenhagen Atrial Fibrillation, Aspirin, and Anticoagulation Study
    • Gullov AL, Koefoed BG, Petersen P, et al. Fixed minidose warfarin and aspirin alone and in combination vs adjusted-dose warfarin for stroke prevention in atrial fibrillation: Second Copenhagen Atrial Fibrillation, Aspirin, and Anticoagulation Study. Arch Intern Med. 1998;158:1513-1521.
    • (1998) Arch Intern Med , vol.158 , pp. 1513-1521
    • Gullov, A.L.1    Koefoed, B.G.2    Petersen, P.3
  • 34
    • 0031666908 scopus 로고    scopus 로고
    • The effect of different antithrombotic regimens on platelet aggregation after myocardial infarction
    • Hurlen M, Seljeflot I, Arnesen H. The effect of different antithrombotic regimens on platelet aggregation after myocardial infarction. Scand Cardiovasc J. 1998;32:233-237.
    • (1998) Scand Cardiovasc J , vol.32 , pp. 233-237
    • Hurlen, M.1    Seljeflot, I.2    Arnesen, H.3
  • 35
    • 0031412594 scopus 로고    scopus 로고
    • Prevalence of anemia and occult blood losses in the long-term follow-up of cardiac mechanic valve patients treated with a combination of low-dose aspirin plus low-intensity acenocoumarin
    • Fondevila CG, Meschengieser SS, Santareli MT, Aixala MT, Lazzari MA. Prevalence of anemia and occult blood losses in the long-term follow-up of cardiac mechanic valve patients treated with a combination of low-dose aspirin plus low-intensity acenocoumarin. Clin Appl Thromb Hemost. 1997;3:36-39.
    • (1997) Clin Appl Thromb Hemost , vol.3 , pp. 36-39
    • Fondevila, C.G.1    Meschengieser, S.S.2    Santareli, M.T.3    Aixala, M.T.4    Lazzari, M.A.5
  • 36
    • 0031011469 scopus 로고    scopus 로고
    • Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: A randomized trial in patients with mechanical prosthetic heart valves
    • Meschengieser SS, Fondevila CG, Frontroth J, Santareli MT, Lazzari MA. Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: a randomized trial in patients with mechanical prosthetic heart valves. J Thorac Cardiovasc Surg. 1997;113: 910-916.
    • (1997) J Thorac Cardiovasc Surg , vol.113 , pp. 910-916
    • Meschengieser, S.S.1    Fondevila, C.G.2    Frontroth, J.3    Santareli, M.T.4    Lazzari, M.A.5
  • 37
    • 0030938396 scopus 로고    scopus 로고
    • Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? some preliminary findings
    • Richards M, Meade TW, Peart S, Brennan PJ, Mann AH. Is there any evidence for a protective effect of antithrombotic medication on cognitive function in men at risk of cardiovascular disease? some preliminary findings. J Neurol Neurosurg Psychiatr. 1997;62:269-272.
    • (1997) J Neurol Neurosurg Psychiatr , vol.62 , pp. 269-272
    • Richards, M.1    Meade, T.W.2    Peart, S.3    Brennan, P.J.4    Mann, A.H.5
  • 38
    • 0031566328 scopus 로고    scopus 로고
    • Coumarin combined with low-dose acetylsalicylic acid in the prevention of thromboembolic complications in patients with mitral and aortic valve prostheses [article in Hungarian]
    • Voith L, Pfliegler G, Hegedus I, et al. Coumarin combined with low-dose acetylsalicylic acid in the prevention of thromboembolic complications in patients with mitral and aortic valve prostheses [article in Hungarian]. Orv Hetil. 1997;138:925-929.
    • (1997) Orv Hetil , vol.138 , pp. 925-929
    • Voith, L.1    Pfliegler, G.2    Hegedus, I.3
  • 39
    • 9544248668 scopus 로고    scopus 로고
    • Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial
    • Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: Stroke Prevention in Atrial Fibrillation III randomised clinical trial. Lancet. 1996;348:633-638.
    • (1996) Lancet , vol.348 , pp. 633-638
  • 40
    • 0027505093 scopus 로고
    • Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke
    • EAFT (European Atrial Fibrillation Trial) Study Group
    • EAFT (European Atrial Fibrillation Trial) Study Group. Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke. Lancet. 1993;342:1255-1262.
    • (1993) Lancet , vol.342 , pp. 1255-1262
  • 41
    • 0027291341 scopus 로고
    • A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement
    • Turpie AG, Gent M, Laupacis A, et al. A comparison of aspirin with placebo in patients treated with warfarin after heart-valve replacement. N Engl J Med. 1993;329:524-529.
    • (1993) N Engl J Med , vol.329 , pp. 524-529
    • Turpie, A.G.1    Gent, M.2    Laupacis, A.3
  • 42
    • 0025251703 scopus 로고
    • Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave myocardial infarction in preventing death and myocardial infarction (a pilot study from the antithrombotic therapy in acute coronary syndromes study group)
    • Cohen M, Adams PC, Bach M, et al. Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave myocardial infarction in preventing death and myocardial infarction (a pilot study from the antithrombotic therapy in acute coronary syndromes study group). Am J Cardiol. 1990;66:1287-1292.
    • (1990) Am J Cardiol , vol.66 , pp. 1287-1292
    • Cohen, M.1    Adams, P.C.2    Bach, M.3
  • 43
    • 0017303863 scopus 로고
    • Prevention of arterial embolism by acetylsalicyclic acid and anticoagulants in patients with heart valve prosthesis [article in Norwegian]
    • Dale J, Myhre E. Prevention of arterial embolism by acetylsalicyclic acid and anticoagulants in patients with heart valve prosthesis [article in Norwegian]. Tidsskr Nor Laegeforen. 1976;96: 1483-1485.
    • (1976) Tidsskr Nor Laegeforen , vol.96 , pp. 1483-1485
    • Dale, J.1    Myhre, E.2
  • 44
    • 0021104088 scopus 로고
    • Trial of combined warfarin plus dipyridamole or aspirin therapy in prosthetic heart valve replacement: Danger of aspirin compared with dipyridamole
    • Chesebro JH, Fuster V, Elveback LR, et al. Trial of combined warfarin plus dipyridamole or aspirin therapy in prosthetic heart valve replacement: danger of aspirin compared with dipyridamole. Am J Cardiol. 1983;51:1537-1541.
    • (1983) Am J Cardiol , vol.51 , pp. 1537-1541
    • Chesebro, J.H.1    Fuster, V.2    Elveback, L.R.3
  • 45
    • 0026634106 scopus 로고
    • Extra-cranial bleeding and other symptoms due to low dose aspirin and low intensity oral anticoagulation
    • Meade TW, Roderick PJ, Brennan PJ, Wilkes HC, Kelleher CC. Extra-cranial bleeding and other symptoms due to low dose aspirin and low intensity oral anticoagulation. Thromb Haemost. 1992; 68:1-6.
    • (1992) Thromb Haemost , vol.68 , pp. 1-6
    • Meade, T.W.1    Roderick, P.J.2    Brennan, P.J.3    Wilkes, H.C.4    Kelleher, C.C.5
  • 46
    • 0019025295 scopus 로고
    • Bleeding during acetylsalicylic acid and anticoagulant therapy in patients with reduced platelet reactivity after aortic valve replacement
    • Dale J, Myhre E, Loew D. Bleeding during acetylsalicylic acid and anticoagulant therapy in patients with reduced platelet reactivity after aortic valve replacement. Am Heart J. 1980;99:746-752.
    • (1980) Am Heart J , vol.99 , pp. 746-752
    • Dale, J.1    Myhre, E.2    Loew, D.3
  • 47
    • 0017741743 scopus 로고
    • Prevention of arterial thromboembolism with acetylsalicylic acid
    • Dale J, Myhre E, Storstein O, et al. Prevention of arterial thromboembolism with acetylsalicylic acid. Am Heart J. 1977;94:101-111.
    • (1977) Am Heart J , vol.94 , pp. 101-111
    • Dale, J.1    Myhre, E.2    Storstein, O.3
  • 48
    • 0016982028 scopus 로고
    • Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves
    • Altman R, Boullon F, Rouvier J, et al. Aspirin and prophylaxis of thromboembolic complications in patients with substitute heart valves. J Thorac Cardiovasc Surg. 1976;72:127-129.
    • (1976) J Thorac Cardiovasc Surg , vol.72 , pp. 127-129
    • Altman, R.1    Boullon, F.2    Rouvier, J.3
  • 49
    • 0035899289 scopus 로고    scopus 로고
    • Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
    • Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK; Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med. 2001;345: 494-502.
    • (2001) N Engl J Med , vol.345 , pp. 494-502
    • Yusuf, S.1    Zhao, F.2    Mehta, S.R.3    Chrolavicius, S.4    Tognoni, G.5    Fox, K.K.6
  • 50
    • 0030297319 scopus 로고    scopus 로고
    • European Stroke Prevention Study, 2: Dipyridamole and acetylsalicylic acid in the secondary prevention of stroke
    • Diener HC, Cunha L, Forbes C, Sivenius J, Smets P, Lowenthal A. European Stroke Prevention Study, 2: dipyridamole and acetylsalicylic acid in the secondary prevention of stroke. J Neurol Sci. 1996; 143:1-13.
    • (1996) J Neurol Sci , vol.143 , pp. 1-13
    • Diener, H.C.1    Cunha, L.2    Forbes, C.3    Sivenius, J.4    Smets, P.5    Lowenthal, A.6
  • 51
    • 0029121472 scopus 로고
    • Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: A meta-analysis
    • Cappelleri JC, Fiore LD, Brophy MT, Deykin D, Lau J. Efficacy and safety of combined anticoagulant and antiplatelet therapy versus anticoagulant monotherapy after mechanical heart-valve replacement: a meta-analysis. Am Heart J. 1995; 130:547-552.
    • (1995) Am Heart J , vol.130 , pp. 547-552
    • Cappelleri, J.C.1    Fiore, L.D.2    Brophy, M.T.3    Deykin, D.4    Lau, J.5
  • 52
    • 0035137978 scopus 로고    scopus 로고
    • Risks and benefits of adding anti-platelet therapy to warfarin among patients with prosthetic heart valves: A meta-analysis
    • Massel D, Little SH. Risks and benefits of adding anti-platelet therapy to warfarin among patients with prosthetic heart valves: a meta-analysis. J Am Coll Cardiol. 2001;37:569-578.
    • (2001) J Am Coll Cardiol , vol.37 , pp. 569-578
    • Massel, D.1    Little, S.H.2
  • 53
    • 0033485480 scopus 로고    scopus 로고
    • Oral anticoagulant therapy in patients with coronary artery disease: A meta-analysis
    • Anand SS, Yusuf S. Oral anticoagulant therapy in patients with coronary artery disease: a meta-analysis. JAMA. 1999;282:2058-2067.
    • (1999) JAMA , vol.282 , pp. 2058-2067
    • Anand, S.S.1    Yusuf, S.2
  • 54
    • 4143120132 scopus 로고    scopus 로고
    • Should aspirin be continued in patients started on warfarin?
    • Larson RJ, Fisher ES. Should aspirin be continued in patients started on warfarin? J Gen Intern Med. 2004;19:879-886.
    • (2004) J Gen Intern Med , vol.19 , pp. 879-886
    • Larson, R.J.1    Fisher, E.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.