The coadministration of paroxetine and low-dose aspirin synergistically enhances gastric ulcerogenic risk in rats

Biological and Pharmaceutical Bulletin

Volumn 31, Issue 7, 2008, Pages 1371-1375

  Yamaguchi, Takumi ^a   Hidaka, Noriaki ^a   Suemaru, Katsuya ^a   Araki, Hiroaki ^a  

^a EHIME UNIVERSITY HOSPITAL   (Japan)

Author keywords

Aspirin; Gastric acid secretion; Paroxetine; Selective serotonin reuptake inhibitor

Indexed keywords

ACETYLSALICYLIC ACID; INDOMETACIN; PAROXETINE; PROSTAGLANDIN E2; SEROTONIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME IMMUNOASSAY; LOW DRUG DOSE; MALE; NONHUMAN; PYLORUS LIGATION; RAT; RISK FACTOR; STOMACH ACID SECRETION; STOMACH HEMORRHAGE; STOMACH INJURY; STOMACH JUICE; STOMACH MUCOSA; STOMACH SECRETION; STOMACH ULCER; ULCEROGENESIS;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SYNERGISM; GASTRIC ACID; GASTRIC MUCOSA; GASTROINTESTINAL HEMORRHAGE; MALE; PAROXETINE; RATS; RATS, WISTAR; SEROTONIN UPTAKE INHIBITORS; STOMACH ULCER;

EID: 46449124525     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.31.1371     Document Type: Article

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