메뉴 건너뛰기




Volumn 5, Issue 2, 2011, Pages 82-94

Exploring novel approaches to vaginal drug delivery

Author keywords

Drug delivery; Hydrogels; Liposomes; Mucoadhesive polymers; Nanoemulsions; Nanoparticles; Vaginal route

Indexed keywords

5 BROMO 6 METHOXY 5,6 DIHYDRO 3' AZIDOTHYMIDINE 5' (4 BROMOPHENYL)METHOXYALANINYL PHOSPHATE; ACICLOVIR; ALGINIC ACID; ANTIRETROVIRUS AGENT; CALCITONIN; CANDID V; CARRAGEENAN; CELLULOSE; CHITOSAN; CLOTRIMAZOLE; DENDRIMER; DRUG CARRIER; ECONAZOLE; GELATIN; HYALURONIC ACID; KETOCONAZOLE; LIPOSOME; METRONIDAZOLE; MICROBICIDE; NANOCARRIER; NANOPARTICLE; NONOXINOL 9; POLYACRYLIC ACID; POLYMER; POVIDONE; PROGESTERONE; S NITROSOGLUTATHIONE; SILVER NANOPARTICLE; THIOMER; UNCLASSIFIED DRUG; UNINDEXED DRUG; VANADOCENE DITHIOCARBAMATE; WHI 07;

EID: 79955643671     PISSN: 18722113     EISSN: None     Source Type: Journal    
DOI: 10.2174/187221111795471418     Document Type: Article
Times cited : (39)

References (120)
  • 1
    • 84908059068 scopus 로고    scopus 로고
    • Roberts MS, Rathbone MJ, Hadgraft J, LaneME, Eds, New York:Marcel Dekker
    • Woolfson AD. In: Roberts MS, Rathbone MJ, Hadgraft J, LaneME, Eds. Intravaginal Drug Delivery Technologies. New York:Marcel Dekker 2008: 754-74.
    • (2008) Intravaginal Drug Delivery Technologies , pp. 754-774
    • Woolfson, A.D.1
  • 2
    • 0000289081 scopus 로고
    • The absorption of drugs and poisons through the vagina
    • Macht DI. The absorption of drugs and poisons through the vagina. J Pharmacol Exp Ther 1918; 10: 509-22.
    • (1918) J Pharmacol Exp Ther , vol.10 , pp. 509-522
    • Macht, D.I.1
  • 3
    • 79955653790 scopus 로고    scopus 로고
    • Novel approaches in vaginaldrug delivery systems for local and systemic treatments
    • Nayak BS, Ellaiah P, Sudhahar D. Novel approaches in vaginaldrug delivery systems for local and systemic treatments. J PharmRes 2010; 3(4): 675-80.
    • (2010) J PharmRes , vol.3 , Issue.4 , pp. 675-680
    • Nayak, B.S.1    Ellaiah, P.2    Sudhahar, D.3
  • 6
    • 0026829774 scopus 로고
    • Routes of delivery: Case studies
    • Richardson JL, Illum L. Routes of delivery: Case studies. AdvDrug Del Rev 1992; 8: 341-66.
    • (1992) AdvDrug Del Rev , vol.8 , pp. 341-366
    • Richardson, J.L.1    Illum, L.2
  • 8
    • 14844314490 scopus 로고    scopus 로고
    • The vagina as a route for systemic drugdelivery
    • Hussain A, Ahsan F. The vagina as a route for systemic drugdelivery. J Control Release 2005; 103(2): 301-13.
    • (2005) J Control Release , vol.103 , Issue.2 , pp. 301-313
    • Hussain, A.1    Ahsan, F.2
  • 9
    • 79955646808 scopus 로고    scopus 로고
    • An overview of intravaginaldrug delivery
    • Chatterjee A, Bhowmik BB, Kumar L. An overview of intravaginaldrug delivery. J Pharm Res 2009; 2(4): 698-700.
    • (2009) J Pharm Res , vol.2 , Issue.4 , pp. 698-700
    • Chatterjee, A.1    Bhowmik, B.B.2    Kumar, L.3
  • 27
    • 0020431391 scopus 로고
    • Results of single-dose treatment of vaginal mycoses with500 mg Canesten vaginal tablets
    • Krause U. Results of single-dose treatment of vaginal mycoses with500 mg Canesten vaginal tablets. Chemotherapy 1982; 28(1): 99-105.
    • (1982) Chemotherapy , vol.28 , Issue.1 , pp. 99-105
    • Krause, U.1
  • 28
    • 0027118617 scopus 로고
    • A new low-dosage estradiolpreparation for local treatment of postmenopausal urogenitalatrophy
    • Eriksen PS, Rasmussen H. Vagifem. A new low-dosage estradiolpreparation for local treatment of postmenopausal urogenitalatrophy. Ugeskr Laeger 1992; 154(16): 1122-4.
    • (1992) Ugeskr Laeger , vol.154 , Issue.16 , pp. 1122-1124
    • Eriksen, P.S.1    Vagifem, R.H.2
  • 29
    • 13244252365 scopus 로고    scopus 로고
    • Theeffectiveness of live lactobacilli in combination with low doseestriol (Gynoflor) to restore the vaginal flora after treatment ofvaginal infections
    • Ozkinay E, Terek MC, Yayci M, Kaiser R, Grob P, Tuncay G. Theeffectiveness of live lactobacilli in combination with low doseestriol (Gynoflor) to restore the vaginal flora after treatment ofvaginal infections. BJOG 2005; 112(2): 234-40.
    • (2005) BJOG , vol.112 , Issue.2 , pp. 234-240
    • Ozkinay, E.1    Terek, M.C.2    Yayci, M.3    Kaiser, R.4    Grob, P.5    Tuncay, G.6
  • 30
    • 79955647341 scopus 로고    scopus 로고
    • Product Information
    • Embil Pharmaceuticals, Available at, Accessed on: Nov11
    • Embil Pharmaceuticals. Product Information. Gynomax Pessary.Available at:http://www.embil.com/default.asp?PAG00_CODE=PRDTR01&MMG00_CODE=002&MMH00_CODE=03EN (Accessed on: Nov11, 2010).
    • (2010) Gynomax Pessary
  • 31
    • 79955653791 scopus 로고    scopus 로고
    • Drugs Information Online. Terazole 3. Available at, (Accessed on: Sep 29,2010)
    • Drugs Information Online. Terazole 3. Available at: http://www.drugs.com/mtm/terazol-3.html (Accessed on: Sep 29,2010).
  • 32
    • 26844529253 scopus 로고    scopus 로고
    • The efficacy and safety of a single dose ofClindesse vaginal cream versus a seven-dose regimen of Cleocinvaginal cream in patients with bacterial vaginosis
    • Faro S, Skokos CK. The efficacy and safety of a single dose ofClindesse vaginal cream versus a seven-dose regimen of Cleocinvaginal cream in patients with bacterial vaginosis. Infect Dis ObstetGynecol 2005; 13(3): 155-60.
    • (2005) Infect Dis ObstetGynecol , vol.13 , Issue.3 , pp. 155-160
    • Faro, S.1    Skokos, C.K.2
  • 33
    • 0032739106 scopus 로고    scopus 로고
    • Butoconazole nitrate 2% forvulvovaginal candidiasis. New, single-dose vaginal creamformulation vs. seven-day treatment with miconazole nitrate.Gynazole 1 Study Group
    • Brown D, Henzl MR, Kaufman RH. Butoconazole nitrate 2% forvulvovaginal candidiasis. New, single-dose vaginal creamformulation vs. seven-day treatment with miconazole nitrate.Gynazole 1 Study Group. J Reprod Med 1999; 44(11): 933-8.
    • (1999) J Reprod Med , vol.44 , Issue.11 , pp. 933-938
    • Brown, D.1    Henzl, M.R.2    Kaufman, R.H.3
  • 34
    • 79955658395 scopus 로고    scopus 로고
    • Drugs Information Online. Synthetic Conjugated Estrogens-A.Available at, Accessed on: Sep 18
    • Drugs Information Online. Synthetic Conjugated Estrogens-A.Available at: http://www.drugs.com/cdi/synthetic-conjugatedestrogens-a-cream.html (Accessed on: Sep 18, 2010).
    • (2010)
  • 35
    • 0035199818 scopus 로고    scopus 로고
    • A randomized study comparing Crinone 8%and intramuscular progesterone supplementation in in vitrofertilization-embryo transfer cycles
    • Propst AM, Hill JA, Ginsburg ES, Hurwitz S, Politch J, Yanushpolsky EH. A randomized study comparing Crinone 8%and intramuscular progesterone supplementation in in vitrofertilization-embryo transfer cycles. Fertil Steril 2001; 76(6): 1144-9.
    • (2001) Fertil Steril , vol.76 , Issue.6 , pp. 1144-1149
    • Propst, A.M.1    Hill, J.A.2    Ginsburg, E.S.3    Hurwitz, S.4    Politch, J.5    Yanushpolsky, E.H.6
  • 36
    • 0035112881 scopus 로고    scopus 로고
    • Safety and tolerability of BufferGel, a novel vaginalmicrobicide, in women in the United States
    • Mayer KH, Peipert J, Fleming T, Fullem A, Moench T, Cu-Uvin S, et al. Safety and tolerability of BufferGel, a novel vaginalmicrobicide, in women in the United States. Clin Infect Dis 2001;32: 476-82.
    • (2001) Clin Infect Dis , vol.32 , pp. 476-482
    • Mayer, K.H.1    Peipert, J.2    Fleming, T.3    Fullem, A.4    Moench, T.5    Cu-Uvin, S.6
  • 37
    • 0027178730 scopus 로고
    • In vitro antimicrobialactivity of tioconazole and its concentration in vaginal fluidsfollowing topical (vagistat-1 6.5%) application
    • Jones RN, Bale MJ, Hoban D, Erwin ME. In vitro antimicrobialactivity of tioconazole and its concentration in vaginal fluidsfollowing topical (vagistat-1 6.5%) application. Diagn Microbiol Infect Dis 1993; 17(1): 45-51.
    • (1993) Diagn Microbiol Infect Dis , vol.17 , Issue.1 , pp. 45-51
    • Jones, R.N.1    Bale, M.J.2    Hoban, D.3    Erwin, M.E.4
  • 38
    • 79955645181 scopus 로고    scopus 로고
    • Drugs Information Online, Available at, Accessed on:Nov 12
    • Drugs Information Online. Gynecure. Available at: http://www.drugs.com/cons/gyne-cure-topical.html (Accessed on:Nov 12, 2010).
    • (2010) Gynecure
  • 39
    • 0016044113 scopus 로고
    • Clinical evaluation of the effectiveness of miconazole invaginal candidiasis
    • Rubio B. Clinical evaluation of the effectiveness of miconazole invaginal candidiasis. Gynecol Obstet Mex 1974; 35(209): 233-9.
    • (1974) Gynecol Obstet Mex , vol.35 , Issue.209 , pp. 233-239
    • Rubio, B.1
  • 40
    • 79955645491 scopus 로고    scopus 로고
    • Drugs Information Online, Femizol-M.Available at, Accessed on: Nov 13
    • Drugs Information Online. Miconazole nitrare. Femizol-M.Available at: http://www.drugs.com/monograph/miconazolenitrate.html (Accessed on: Nov 13, 2010).
    • (2010) Miconazole Nitrare
  • 41
    • 36348998080 scopus 로고    scopus 로고
    • Phase I/IIclinical safety studies of terameprocol vaginal ointment
    • Khanna N, Dalby R, Tan M, Arnold S, Stern J, Frazer N. Phase I/IIclinical safety studies of terameprocol vaginal ointment. Gynecol Oncol 2007; 107(3): 554-62.
    • (2007) Gynecol Oncol , vol.107 , Issue.3 , pp. 554-562
    • Khanna, N.1    Dalby, R.2    Tan, M.3    Arnold, S.4    Stern, J.5    Frazer, N.6
  • 43
    • 0035988934 scopus 로고    scopus 로고
    • Safety and tolerability of the newcontraceptive sponge Protectaid
    • Creatsas G, Elsheikh A, Colin P. Safety and tolerability of the newcontraceptive sponge Protectaid. Eur J Contacept Reprod HealthCare 2002; 7(2): 91-5.
    • (2002) Eur J Contacept Reprod HealthCare , vol.7 , Issue.2 , pp. 91-95
    • Creatsas, G.1    Elsheikh, A.2    Colin, P.3
  • 44
    • 79955668658 scopus 로고    scopus 로고
    • Foamix, Available at, Accessed on:Nov 17
    • Foamix. Foamix Unveils Innovative Vaginal Foam. Available at: http://www.foamix.co.il/InnovativeVaginal.html (Accessed on:Nov 17, 2010).
    • (2010) Foamix Unveils Innovative Vaginal Foam
  • 45
    • 84889644096 scopus 로고    scopus 로고
    • Candida Free, Available at, Accessed on: Nov 25
    • Candida Free. Resources. Available at: www.candidafree.net/resource_17.htm (Accessed on: Nov 25,2010).
    • (2010) Resources
  • 46
    • 0033002046 scopus 로고    scopus 로고
    • A randomized, open, parallel-group study on thepreventive effect of an estradiol-releasing vaginal ring (Estring) onrecurrent urinary tract infectionsin postmenopausal women
    • Eriksen B. A randomized, open, parallel-group study on thepreventive effect of an estradiol-releasing vaginal ring (Estring) onrecurrent urinary tract infectionsin postmenopausal women. Am JObstet Gynecol 1999; 180(5): 1072-9.
    • (1999) Am JObstet Gynecol , vol.180 , Issue.5 , pp. 1072-1079
    • Eriksen, B.1
  • 47
    • 79955673291 scopus 로고    scopus 로고
    • Drug Information Online, Available at, Accessed on: Sep 26
    • Drug Information Online. Femring Ring. Available at: http://www.drugs.com/cdi/femring-ring.html (Accessed on: Sep 26, 2010).
    • (2010) Femring Ring
  • 48
    • 79955675343 scopus 로고    scopus 로고
    • America Rx.com, Available at, Accessed on: Dec 4
    • America Rx.com. Summer's Eve Douche. Available at: http://www.americarx.com/brandpages/summers_eve_douche_productname_asc_25_1.html (Accessed on: Dec 4, 2010).
    • (2010) Summer's Eve Douche
  • 49
    • 79955675829 scopus 로고    scopus 로고
    • Drug Information Online, Available at, Accessed on: Aug 19
    • Drug Information Online. Massengil feminine cleansing wash. Available at: http://www.drugs.com/drp/massengill-femininecleansing-wash.html (Accessed on: Aug 19, 2010).
    • (2010) Massengil Feminine Cleansing Wash
  • 50
    • 79955671956 scopus 로고    scopus 로고
    • Drug Information Online, Availble at, Accessed on:Aug 29
    • Drug Information Online. Betadine Douche. Availble at: http://www.drugs.com/cdi/betadine-douche.html (Accessed on:Aug 29, 2010).
    • (2010) Betadine Douche
  • 53
    • 0037436923 scopus 로고    scopus 로고
    • Bioadhesive microspheres as acontrolled drug delivery system
    • Vasir JK, Tambwekar K, Garg S. Bioadhesive microspheres as acontrolled drug delivery system. Int J Pharm 2003; 255(1-2): 13-32.
    • (2003) Int J Pharm , vol.255 , Issue.1-2 , pp. 13-32
    • Vasir, J.K.1    Tambwekar, K.2    Garg, S.3
  • 54
    • 11144319352 scopus 로고    scopus 로고
    • Pharmaceutical applications ofmucoadhesion for the non-oral routes
    • Edsman K, Hagerstrom H. Pharmaceutical applications ofmucoadhesion for the non-oral routes. J Pharm Pharmacol 2005;57(1):3-22.
    • (2005) J Pharm Pharmacol , vol.57 , Issue.1 , pp. 3-22
    • Edsman, K.1    Hagerstrom, H.2
  • 55
    • 73549112447 scopus 로고    scopus 로고
    • Polymers inMucoadhesive Drug Delivery System: A brief note
    • Roy S, Pal K, Anis A, Pramanik K, Prabhakar B. Polymers inMucoadhesive Drug Delivery System: A brief note. Des Monomers Polym 2009; 12(6): 483-95.
    • (2009) Des Monomers Polym , vol.12 , Issue.6 , pp. 483-495
    • Roy, S.1    Pal, K.2    Anis, A.3    Pramanik, K.4    Prabhakar, B.5
  • 56
    • 0036451610 scopus 로고    scopus 로고
    • Chitosan andSodium alginate-based bioadhesive vaginal tablets
    • El-Kamel A, Sokar M, Naggar V, Al Gamal S. Chitosan andSodium alginate-based bioadhesive vaginal tablets. AAPS Pharm Sci 2002; 4(4): E44.
    • (2002) AAPS Pharm Sci , vol.4 , Issue.4
    • El-Kamel, A.1    Sokar, M.2    Naggar, V.3    Gamal, A.S.4
  • 62
    • 0034306493 scopus 로고    scopus 로고
    • The scope and potential of vaginal drugdelivery
    • Garg S, Vermani K. The scope and potential of vaginal drugdelivery. Pharm Sci Technol To 2000; 3(10): 359-64.
    • (2000) Pharm Sci Technol To , vol.3 , Issue.10 , pp. 359-364
    • Garg, S.1    Vermani, K.2
  • 63
    • 0021236615 scopus 로고
    • An in vitro investigationof mucosa-adhesive materials for use in controlled drug delivery
    • Smart JD, Kellaway IW, Worthington HE. An in vitro investigationof mucosa-adhesive materials for use in controlled drug delivery. J Pharm Pharmacol 1984; 36(5): 295-9.
    • (1984) J Pharm Pharmacol , vol.36 , Issue.5 , pp. 295-299
    • Smart, J.D.1    Kellaway, I.W.2    Worthington, H.E.3
  • 64
    • 70350762116 scopus 로고    scopus 로고
    • Mucoadhesive vaginal drug delivery systems
    • Acarturk F. Mucoadhesive vaginal drug delivery systems. Recent Pat Drug Deliv Formul 2009; 3(3): 193-205.
    • (2009) Recent Pat Drug Deliv Formul , vol.3 , Issue.3 , pp. 193-205
    • Acarturk, F.1
  • 65
    • 1042278866 scopus 로고    scopus 로고
    • Efficacy of a newketoconazole bioadhesive vaginal tablet on Candida albicans
    • Karasulu HY, Hilmio S, Metin DY, Guneri T. Efficacy of a newketoconazole bioadhesive vaginal tablet on Candida albicans.Farmaco 2004; 59(2): 163-7.
    • (2004) Farmaco , vol.59 , Issue.2 , pp. 163-167
    • Karasulu, H.Y.1    Hilmio, S.2    Metin, D.Y.3    Guneri, T.4
  • 66
    • 38549137950 scopus 로고    scopus 로고
    • Chitosan citrate as multifunctional polymer for vaginal deliveryevaluationof penetration enhancement and peptidase inhibitionproperties
    • Bonferoni MC, Sandri G, Rossi S, Ferrari F, Gibin S, Caramella C. Chitosan citrate as multifunctional polymer for vaginal deliveryevaluationof penetration enhancement and peptidase inhibitionproperties. Eur J Pharm Sci 2008; 33(2): 166-76.
    • (2008) Eur J Pharm Sci , vol.33 , Issue.2 , pp. 166-176
    • Bonferoni, M.C.1    Sandri, G.2    Rossi, S.3    Ferrari, F.4    Gibin, S.5    Caramella, C.6
  • 67
    • 23144465315 scopus 로고    scopus 로고
    • Mucoadhesive vaginal tablets as veterinary delivery system for thecontrolled release of an antimicrobial drug, acriflavine
    • Gavini E, Sanna V, Juliano C, Bonferoni MC, Giunchedi P. Mucoadhesive vaginal tablets as veterinary delivery system for thecontrolled release of an antimicrobial drug, acriflavine. AAPS PharmSci 2002; 3(3): E20.
    • (2002) AAPS PharmSci , vol.3 , Issue.3
    • Gavini, E.1    Sanna, V.2    Juliano, C.3    Bonferoni, M.C.4    Giunchedi, P.5
  • 70
    • 0031724086 scopus 로고    scopus 로고
    • Carrageenan- basednonoxynol-9 spermicides for prevention of sexually transmittedinfections
    • Maguire RA, Zacharopoulos VR, Phillips DM. Carrageenan- basednonoxynol-9 spermicides for prevention of sexually transmittedinfections. Sex Transm Dis 1998; 25(9): 494- 500.
    • (1998) Sex Transm Dis , vol.25 , Issue.9 , pp. 494-500
    • Maguire, R.A.1    Zacharopoulos, V.R.2    Phillips, D.M.3
  • 71
    • 67349219709 scopus 로고    scopus 로고
    • Effect of carrageenan on poloxamerbasedin situ gel for vaginal use: Improved in vitro and in vivosustained-release properties
    • Liu Y, Zhu Y, Wei G, Lu W. Effect of carrageenan on poloxamerbasedin situ gel for vaginal use: Improved in vitro and in vivosustained-release properties. Eur J Pharm Sci 2009; 37(3-4): 306-12.
    • (2009) Eur J Pharm Sci , vol.37 , Issue.3-4 , pp. 306-312
    • Liu, Y.1    Zhu, Y.2    Wei, G.3    Lu, W.4
  • 72
    • 0036451610 scopus 로고    scopus 로고
    • Chitosan and sodiumalginate-based bioadhesive vaginal tablets
    • El-Kamel A, Sokar M, Naggar V, Gamal SA. Chitosan and sodiumalginate-based bioadhesive vaginal tablets. AAPS PharmSci 2002;4 (4): E44.
    • (2002) AAPS PharmSci , vol.4 , Issue.4
    • El-Kamel, A.1    Sokar, M.2    Naggar, V.3    Gamal, S.A.4
  • 73
    • 31144448147 scopus 로고    scopus 로고
    • The physicodynamic properties ofmucoadhesive polymeric films developed as female controlled drugdelivery system
    • Lee CH, Dharmala K, Yoo JW. The physicodynamic properties ofmucoadhesive polymeric films developed as female controlled drugdelivery system. Int J Pharm 2006; 309(1-2): 139-45.
    • (2006) Int J Pharm , vol.309 , Issue.1-2 , pp. 139-145
    • Lee, C.H.1    Dharmala, K.2    Yoo, J.W.3
  • 74
    • 79955675337 scopus 로고    scopus 로고
    • Thiomers: Forms, features andformulations
    • Samuel AJ, Kulkarni M, Tambe R. Thiomers: Forms, features andformulations. J Chem Pharm Res 2010; 2(6): 316-23.
    • (2010) J Chem Pharm Res , vol.2 , Issue.6 , pp. 316-323
    • Samuel, A.J.1    Kulkarni, M.2    Tambe, R.3
  • 75
    • 57149144115 scopus 로고    scopus 로고
    • Effect of thiolatedpolymers to textural and mucoadhesive properties of vaginal gelformulations prepared with polycarbophil and chitosan
    • Cevher E, Sensoy D, Taha M, Araman A. Effect of thiolatedpolymers to textural and mucoadhesive properties of vaginal gelformulations prepared with polycarbophil and chitosan. AAPS Pharm Sci Tech 2008; 9(3): 953-65.
    • (2008) AAPS Pharm Sci Tech , vol.9 , Issue.3 , pp. 953-965
    • Cevher, E.1    Sensoy, D.2    Taha, M.3    Araman, A.4
  • 76
    • 77950361652 scopus 로고    scopus 로고
    • Strategies toprolong the intravaginal residence time of drug delivery systems
    • Baloglu E, Senyigit ZA, Karavana SY, Schnurch AB. Strategies toprolong the intravaginal residence time of drug delivery systems. JPharm Pharmaceut Sci 2009; 12(3): 312-36.
    • (2009) JPharm Pharmaceut Sci , vol.12 , Issue.3 , pp. 312-336
    • Baloglu, E.1    Senyigit, Z.A.2    Karavana, S.Y.3    Schnurch, A.B.4
  • 77
    • 73549099755 scopus 로고    scopus 로고
    • Development of topical microbicides to prevent the sexualtransmission of HIV
    • Buckheit Jr RW, Watson KM, Morrow KM, Ham AS. Development of topical microbicides to prevent the sexualtransmission of HIV. Antivir Res 2010; 85(1): 142-58.
    • (2010) Antivir Res , vol.85 , Issue.1 , pp. 142-158
    • Buckheit, R.W.1    Watson, K.M.2    Morrow, K.M.3    Ham, A.S.4
  • 78
    • 70449524333 scopus 로고    scopus 로고
    • A novel itraconazole bioadhesivefilm for vaginal delivery: Design, optimization, andphysicodynamic characterization
    • Dobaria N, Badhan A, Mashru R. A novel itraconazole bioadhesivefilm for vaginal delivery: Design, optimization, andphysicodynamic characterization. AAPS Pharm SciTech 2009;10(3): 951-9.
    • (2009) AAPS Pharm Sci Tech , vol.10 , Issue.3 , pp. 951-959
    • Dobaria, N.1    Badhan, A.2    Mashru, R.3
  • 79
    • 67349181056 scopus 로고    scopus 로고
    • In vivo evaluation of vaginal filmsfor mucosal delivery of nitric oxide
    • Yoo JW, Acharya G, Lee CH. In vivo evaluation of vaginal filmsfor mucosal delivery of nitric oxide. Biomaterials 2009; 30(23-24):3978-85.
    • (2009) Biomaterials , vol.30 , Issue.23-24 , pp. 3978-3985
    • Yoo, J.W.1    Acharya, G.2    Lee, C.H.3
  • 81
    • 59349094139 scopus 로고    scopus 로고
    • Polymer-lipid based mucoadhesive microspheresprepared by spray-congealing for the vaginal delivery of econazolenitrate
    • Albertini B, Passerini N, Sabatino MD, Vitali B, Brigidi P, Rodriguez L. Polymer-lipid based mucoadhesive microspheresprepared by spray-congealing for the vaginal delivery of econazolenitrate. Eur J Pharm Sci 2009; 36(4-5): 591-601.
    • (2009) Eur J Pharm Sci , vol.36 , Issue.4-5 , pp. 591-601
    • Albertini, B.1    Passerini, N.2    Sabatino, M.D.3    Vitali, B.4    Brigidi, P.5    Rodriguez, L.6
  • 82
    • 23744471772 scopus 로고    scopus 로고
    • Drug targeting with nano-sized carrier
    • Yokoyama M. Drug targeting with nano-sized carrier. J ArtifOrgans 2005; 8(2): 77-84.
    • (2005) J ArtifOrgans , vol.8 , Issue.2 , pp. 77-84
    • Yokoyama, M.1
  • 88
    • 77954403578 scopus 로고    scopus 로고
    • PVP-coated silver nanoparticles block the transmissionof cell-free and cell-associated HIV-1 in human cervical culture
    • Lara HH, Ixtepan-Turrent L, Garza-Trevino EN, Rodriguez-Padilla C. PVP-coated silver nanoparticles block the transmissionof cell-free and cell-associated HIV-1 in human cervical culture. J Nanobiotechnology 2010; 8:15.
    • (2010) J Nanobiotechnology , vol.8 , pp. 15
    • Lara, H.H.1    Ixtepan-Turrent, L.2    Garza-Trevino, E.N.3    Rodriguez-Padilla, C.4
  • 91
    • 0024470454 scopus 로고
    • Site specific drug delivery using liposomes as carriers
    • Ranade W. Site specific drug delivery using liposomes as carriers. J Clin Pharmacol 1989; 29(8): 685-94.
    • (1989) J Clin Pharmacol , vol.29 , Issue.8 , pp. 685-694
    • Ranade, W.1
  • 92
    • 0035927213 scopus 로고    scopus 로고
    • Liposomal gels forvaginal drug delivery
    • Pavelic Z, Skalko-Basnet N, Schubert R. Liposomal gels forvaginal drug delivery. Int J Pharm 2001; 219(1-2): 139-49.
    • (2001) Int J Pharm , vol.219 , Issue.1-2 , pp. 139-149
    • Pavelic, Z.1    Skalko-Basnet, N.2    Schubert, R.3
  • 93
    • 22244453965 scopus 로고    scopus 로고
    • Conceival, a novelnoncontraceptive vaginal vehicle for lipophilicmicrobicides
    • D'Cruz OJ, Samuel P, Uckun FM. Conceival, a novelnoncontraceptive vaginal vehicle for lipophilicmicrobicides. AAPS Pharm SciTech 2005; 06(01): E56-64.
    • (2005) AAPS Pharm Sci Tech , vol.6 , Issue.1
    • D'Cruz, O.J.1    Samuel, P.2    Uckun, F.M.3
  • 95
    • 3743150592 scopus 로고
    • Dendrimers in supramolecular chemistry:From molecular recognition to self-assembly
    • Zeng F, Zimmerman SC. Dendrimers in supramolecular chemistry:From molecular recognition to self-assembly. Chem Rev 1977;97(5): 1681-712.
    • (1977) Chem Rev , vol.97 , Issue.5 , pp. 1681-1712
    • Zeng, F.1    Zimmerman, S.C.2
  • 96
    • 77953405055 scopus 로고    scopus 로고
    • Dendrimers:Nanotechnology Derived Novel Polymers in Drug Delivery
    • Pushkar S, Philip A, Pathak K, Pathak D. Dendrimers:Nanotechnology Derived Novel Polymers in Drug Delivery. Indian J Pharm Edu Res 2006; 40(3): 153-8.
    • (2006) Indian J Pharm Edu Res , vol.40 , Issue.3 , pp. 153-158
    • Pushkar, S.1    Philip, A.2    Pathak, K.3    Pathak, D.4
  • 97
    • 16444385352 scopus 로고    scopus 로고
    • SPL7013 gel as a topical microbicide for prevention ofvaginal transmission of SHIV89.6P in macaques
    • Jiang YH, Emau P, Cairns JS, Flanary L, Morton WR, McCarthy TD, et al. SPL7013 gel as a topical microbicide for prevention ofvaginal transmission of SHIV89.6P in macaques. AIDS Res Hum Retroviruses 2005; 21(3): 207-13.
    • (2005) AIDS Res Hum Retroviruses , vol.21 , Issue.3 , pp. 207-213
    • Jiang, Y.H.1    Emau, P.2    Cairns, J.S.3    Flanary, L.4    Morton, W.R.5    McCarthy, T.D.6
  • 98
    • 79955653132 scopus 로고    scopus 로고
    • NanoBio Corporation, Available at, Accessed on: Oct 26
    • NanoBio Corporation. Platform Tech. Available at: http://www.nanobio.com/Platform-Technology/NanoStat-Platform.html (Accessed on: Oct 26, 2010).
    • (2010) Platform Tech
  • 102
    • 33748697001 scopus 로고    scopus 로고
    • Influence of long-term stability conditionson microbicidal nucleoside prodrug (WHI-07)-loaded gelmicroemulsion
    • D'Cruz OJ, Uckun FM. Influence of long-term stability conditionson microbicidal nucleoside prodrug (WHI-07)-loaded gelmicroemulsion. AAPS Pharm SciTech 2006; 7(3): 73.
    • (2006) AAPS Pharm SciTech , vol.7 , Issue.3 , pp. 73
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 103
    • 32644438459 scopus 로고    scopus 로고
    • Dawn of non-nucleoside inhibitor-basedanti-HIV microbicides
    • D'Cruz OJ, Uckun FM. Dawn of non-nucleoside inhibitor-basedanti-HIV microbicides. J Antimicrob Chemother 2006; 57(3): 411-23.
    • (2006) J Antimicrob Chemother , vol.57 , Issue.3 , pp. 411-423
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 104
    • 67549130678 scopus 로고    scopus 로고
    • Microemulsion-based vaginal gel ofclotrimazole: Formulation, in vitro evaluation, and stability studies
    • Bachhav YG, Patravale VB. Microemulsion-based vaginal gel ofclotrimazole: formulation, in vitro evaluation, and stability studies. AAPS Pharm Sci Tech 2009; 10(2): 476-81.
    • (2009) AAPS Pharm Sci Tech , vol.10 , Issue.2 , pp. 476-481
    • Bachhav, Y.G.1    Patravale, V.B.2
  • 105
    • 37549068611 scopus 로고    scopus 로고
    • Preclinical evaluation of a dual-actingmicrobicidal prodrug WHI-07 in combination with vanadocenedithiocarbamate in the female reproductive tract of rabbit, pig, andcat
    • D'Cruz OJ, Uckun FM. Preclinical evaluation of a dual-actingmicrobicidal prodrug WHI-07 in combination with vanadocenedithiocarbamate in the female reproductive tract of rabbit, pig, andcat. Toxicol Pathol 2007; 35(7): 910-27.
    • (2007) Toxicol Pathol , vol.35 , Issue.7 , pp. 910-927
    • D'Cruz, O.J.1    Uckun, F.M.2
  • 108
    • 64249134708 scopus 로고    scopus 로고
    • The relationship betweensuperior attachment points for anterior wall mesh operations andthe upper vagina using a 3-dimensional magnetic resonance modelin women with normal support
    • e1-e6
    • Larson KA, Hsu Y, De Lancey JO. The relationship betweensuperior attachment points for anterior wall mesh operations andthe upper vagina using a 3-dimensional magnetic resonance modelin women with normal support. Am J Ostet Gynecol 2009; 200(5):554, e1-6.
    • (2009) Am J Ostet Gynecol , vol.200 , Issue.5 , pp. 554
    • Larson, K.A.1    Hsu, Y.2    de Lancey, J.O.3
  • 109
    • 0001885892 scopus 로고    scopus 로고
    • Current status of drug delivery technologiesand future directions
    • Verma RK, Garg S. Current status of drug delivery technologiesand future directions. Pharmaceutical Technology On-Line 2001;25(2): 1-14.
    • (2001) Pharmaceutical Technology On-Line , vol.25 , Issue.2 , pp. 1-14
    • Verma, R.K.1    Garg, S.2
  • 110
    • 0032876041 scopus 로고    scopus 로고
    • Vaginal drug delivery
    • Barnhart K. Vaginal drug delivery. IDrugs 1999; 2: 756-9.
    • (1999) IDrugs , vol.2 , pp. 756-759
    • Barnhart, K.1
  • 111
    • 38949198100 scopus 로고    scopus 로고
    • Vivagel (SPL7013 Gel): Acandidate dendrimer-microbicidefor the prevention of of HIV andHSV infection
    • Rupp R, Rosenthal SL, Stanberry LR. Vivagel (SPL7013 Gel): Acandidate dendrimer-microbicidefor the prevention of of HIV andHSV infection. Int J Nanomedicine 2007; 2(4): 56-6.
    • (2007) Int J Nanomedicine , vol.2 , Issue.4 , pp. 56-56
    • Rupp, R.1    Rosenthal, S.L.2    Stanberry, L.R.3
  • 112
    • 79955670747 scopus 로고    scopus 로고
    • Drugs Information Online, Available at, Accessed on:Nov 26
    • Drugs Information Online. Clotrimazole Consumer Information.Available at: www.drugs.com/mtm/mycelex-g.html (Accessed on:Nov 26, 2010).
    • (2010) Clotrimazole Consumer Information
  • 113
    • 79955658724 scopus 로고    scopus 로고
    • ASIA Pharmaceutical Industries, Available at, Accessed on: Dec 8
    • ASIA Pharmaceutical Industries. Product Search. Available at: http://www.asiapharma-syria.com/en/product-search/Hormones(Accessed on: Dec 8, 2010).
    • (2010) Product Search
  • 115
    • 0031838440 scopus 로고    scopus 로고
    • Metronidazole vaginal gel 0.75% (Metrogel-vaginal): Abrief review
    • Wain AM. Metronidazole vaginal gel 0.75% (Metrogel-vaginal): abrief review. Infect Dis Obstet Gynecol 1998; 6(1): 3-7.
    • (1998) Infect Dis Obstet Gynecol , vol.6 , Issue.1 , pp. 3-7
    • Wain, A.M.1
  • 116
    • 0022939137 scopus 로고
    • Safety and efficacy of Estrace (micronized 17 betaestradiol)
    • Martin PL. Safety and efficacy of Estrace (micronized 17 betaestradiol). Int J Fertil 1986; 31: 39-44.
    • (1986) Int J Fertil , vol.31 , pp. 39-44
    • Martin, P.L.1
  • 117
    • 50349091273 scopus 로고    scopus 로고
    • The surgical technique and early postoperative the GynecareProlift pelvic floor repair system
    • Lucioni A, Rapp DE, Gong EM, Reynolds WS, Fedunok PA, Bales GT. The surgical technique and early postoperative the GynecareProlift pelvic floor repair system. Can J Urol 2008; 15(2): 4004-8.
    • (2008) Can J Urol , vol.15 , Issue.2 , pp. 4004-4008
    • Lucioni, A.1    Rapp, D.E.2    Gong, E.M.3    Reynolds, W.S.4    Fedunok, P.A.5    Bales, G.T.6
  • 118
    • 79955666475 scopus 로고    scopus 로고
    • RxList. The Internet Drug Index, Available at, Accessed on: Dec 20
    • RxList. The Internet Drug Index. Aci-Jel. Available at: http://www.rxlist.com/aci-jel-drug.htm (Accessed on: Dec 20,2010).
    • (2010) Aci-Jel
  • 119
    • 79955652078 scopus 로고    scopus 로고
    • Netdoctor. Medicines. Zidoval. Available at, Accessed on: Dec 18
    • Netdoctor. Medicines. Zidoval. Available at: www.netdoctor.co.uk/medicines/100002840.html (Accessed on: Dec 18, 2010).
    • (2010)
  • 120
    • 0029757133 scopus 로고    scopus 로고
    • Systemic delivery of peptides and proteinsacross absorptive mucosae
    • Sayani AP, Chien YW. Systemic delivery of peptides and proteinsacross absorptive mucosae. Crit Rev Ther Drug Carrier Syst 1996;13(1-2): 85-184.
    • (1996) Crit Rev Ther Drug Carrier Syst , vol.13 , Issue.1-2 , pp. 85-184
    • Sayani, A.P.1    Chien, Y.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.