Tonsillar CD4+FOXP3+ T-regulatory cell dynamics in primary EBV infection

Immunologic Research

Volumn 50, Issue 1, 2011, Pages 97-101

  Chow, Yen Hung ^a   Chang, Hsuen Wen ^a   Sia, Raymond ^a   Chong, Pele ^a   Sia, Charles ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

CD4+FOXP3+ Treg cells; EBV lytic cycle; Tonsils

Indexed keywords

CD4 ANTIGEN; COMPLEMENT COMPONENT C3D RECEPTOR; INTERLEUKIN 2; INTERLEUKIN 6; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA;

B LYMPHOCYTE; DENDRITIC CELL; DNA POLYMORPHISM; EPSTEIN BARR VIRUS; EPSTEIN BARR VIRUS INFECTION; HUMAN; LEUKOCYTE ACTIVATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; TONSIL;

B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CYTOKINES; EPSTEIN-BARR VIRUS INFECTIONS; FORKHEAD TRANSCRIPTION FACTORS; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOMODULATION; PALATINE TONSIL; T-LYMPHOCYTES, REGULATORY;

EID: 79955635844     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-010-8174-x     Document Type: Review

References (45)

1. Bornkamm GW, Delius H, Zimber U, Hudewentz J, Epstein MA. Comparison of Epstein-Barr virus strains of different origin by analysis of the viral DNAs. J Virol. 1980;35(3):603-18. (Pubitemid 11217790)
2. Sixbey J, Shirley P, Chesney P, Buntin D, Resnick L. Detection of a second widespread strain of Epstein-Barr virus. Lancet. 1989;2:761-5. (Pubitemid 19234808)
3. Abdel-Hamid M, Chen J-J, Constantine N, Massoud M, Raabtraub N. EBV strain variation: geographical distribution and relation to disease state. Virology. 1992;190(1):168-75.
4. Rickinson AB, Kief E. In: Knipe DM, Howley PM, editors. Fields' virology. Philadelphia: Lippincott Williams & Wilkins; 2001. p. 2575-2627.
5. Tattevin P, Le Tulzo Y, Minjolle S, Person A, Chapplain JM, Arvieux C, Thomas R, Michelet C. Increasing incidence of severe Epstein-Barr virus-related infectious mononucleosis: surveillance study. J Clin Microbiol. 2006;44:1873-4. (Pubitemid 43726289)
6. Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol. 1995;155:1151-64.
7. high regulatory cells in human peripheral blood. J Immunol. 2001; 167:1245-53.
8. Wingate PJ, MaAulay KA, Crawford DH. Regulatory T cell activity in primary and persistent Epstein-Barr virus infection. J Med Virol. 2009;81:870-7.
9. Perry M, Whyte A. Immunology of the tonsils. Immunol Today. 1998;19:414-21. (Pubitemid 28389703)
10. Lim HW, Broxmeyer HE, Kim CH. Regulation of trafficking receptor expression in human forkhead box P3+ regulatory T cells. J Immunol. 2006;177:840-51.
11. Yagi H, Nomura T, Nakamura K, Yamazaki S, Kitawaki T, Hori S, Maeda M, Onodera M, Uchiyama T, Fujii S, Sakaguchi S. Crucial role of FOXP3 in the development and function of human CD25+CD4+ regulatory T cells. Int Immunol. 2004;16:1643-56.
12. Fontenot JD, Rudensky AY. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. Nat Immunol. 2005;6:331-7. (Pubitemid 41716769)
13. Sancho D, Gomez M, Sanchez-Madrid F. CD69 is an immunoregulatory molecule induced following activation. Trends Immunol. 2005;26:136-40. (Pubitemid 40312520)
14. Lim HW, Hillsamer P, Kim CH. Regulatory T cells can migrate to follicles upon T cell activation and suppress GC-Th cells and GC-Th cell-driven B cell responses. J Clin Invest. 2004;114:1640-9.
15. Miyara M, Yoshioka Y, Kitoh A, Shima T, Wing K, Niwa A, Parizot C, Taflin C, Heike T, Valeyre D, Mathian A, Nakahata T, Yamaguchi T, Nomura T, Ono M, Amoura Z, Gorochov G, Sakaguchi S. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity. 2009;30:899-911.
16. + regulatory T cells in humans. Proc Natl Acad Sci USA. 2009;106:4793-8.
17. Allakhverdi Z, Fitzpatrick D, Boisvert A, Baba N, Bouguermouh S, Sarfati M, Delespesse G. Expression of CD103 identifies human regulatory T-cell subsets. J Allergy Clin Immunol. 2006;118:1342-9. (Pubitemid 44854109)
18. Tsuchiya B, Sato Y, Kameya T, Okayasu I, Mukai K. Differential expression of N-cadherin and E-cadherin in normal human tissues. Arch Histol Cytol. 2006;69:135-45.
19. Fingeroth JD, Weis JJ, Tedder TF, Strominger JL, Biro PA, Fearon DT. Epstein-Barr virus receptor of human B lymphocytes is the C3d receptor CR2. Proc Natl Acad Sci USA. 1984;81:4510-4. (Pubitemid 14055921)
20. Fischer E, Delibrias C, Kazatchkine MD. Expression of CR2 (the C3dg/EBV receptor, CD21) on normal human peripheral blood T lymphocytes. J Immunol. 1991;146:865-9.
21. Hsiao FC, Lin M, Tai A, Chen G, Huber BT. Cutting edge: Epstein-Barr virus transactivates the HERV-K18 superantigen by docking to the human complement receptor 2 (CD21) on primary B cells. J Immunol. 2006;177:2056-60. (Pubitemid 44200962)
22. Sutkowski N, Conrad B, Thorley-Lawson DA, Huber BT. Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity. 2001;15:579-89. (Pubitemid 33016443)
23. Renno T, Attinger A, Locatelli S, Bakker T, Vacheron S, MacDonald HR. Cutting edge: apoptosis of superantigen-activated T cells occurs preferentially after a discrete number of cell divisions in vivo. J Immunol. 1999;162:6312-5. (Pubitemid 29309348)
24. Maloy KJ, Powrie F. Regulatory T cells in the control of immune pathology. Nat Immunol. 2001;2:816-22.
25. Crawford DH, Swerdlow AJ, Higgins C, McAulay K, Harrison N, Williams H, Britton K, Macsween KF. Sexual history and Epstein-Barr virus infection. J Infect Dis. 2002;186:731-6. (Pubitemid 35013423)
26. Tanner JE, Alfieri C, Chatila TA, Diaz-Mitoma F. Induction of interleukin-6 after stimulation of human B-cell CD21 by Epstein-Barr virus glycoproteins gp350 and gp220. J Virol. 1996;70:570-5. (Pubitemid 126508826)
27. D'Addario M, Libermann TA, Xu J, Ahmad A, Menezes J. Epstein-Barr Virus and its glycoprotein-350 upregulate IL-6 in human B-lymphocytes via CD21, involving activation of NF-kappaB and different signaling pathways. J Mol Biol. 2001;308:501-14. (Pubitemid 33027615)
28. Scala G, Kuang YD, Hall RE, Muchmore AV, Oppenheim JJ. Accessory cell function of human B cells. I. Production of both interleukin 1-like activity and an interleukin 1 inhibitory factor by an EBV-transformed human B cell line. J Exp Med. 1984;159:1637-52.
29. Bonnefoy JY, Denoroy MC, Guillot O, Martens CL, Banchereau J. Activation of normal human B cells through their antigen receptor induces membrane expression of IL-1 alpha and secretion of IL-1 beta. J Immunol. 1989;143:864-9. (Pubitemid 19203811)
30. Deknuydt F, Bioley G, Valmori D, Ayyoub M. IL-1beta and IL-2 convert human Treg into T(H)17 cells. Clin Immunol. 2009;131:298-307.
31. Hurme M, Helminen M. Polymorphism of the IL-1 gene complex in Epstein-Barr virus seronegative and seropositive adult blood donors. Scand J Immunol. 1998;48:219-22. (Pubitemid 28416961)
32. Quiding M, Granström G, Nordström I, Ferrua B, Holmgren J, Czerkinsky C. High frequency of spontaneous interferon-gamma-producing cells in human tonsils: role of local accessory cells and soluble factors. Clin Exp Immunol. 1993;91(1):157-63. (Pubitemid 23028016)
33. Li B, Samanta A, Song X, Iacono KT, Bembas K, Tao R, Basu S, Riley JL, Hancock WW, Shen Y, et al. FOXP3 interactions with histone acetyltransferase and class II histone deacetylases are required for repression. Proc Natl Acad Sci USA. 2007;104:4571-6.
34. Maloy KJ, Powrie F. Fueling regulation: IL-2 keeps CD4+ Treg cells fit. Nat Immunol. 2005;6:1071-2. (Pubitemid 41541782)
35. Furtado GC, Curotto de Lafaille MA, Kutchukhidze N, Lafaille JJ. Interleukin 2 signaling is required for CD4(+) regulatory T cell function. J Exp Med. 2002;196:851-7.
36. Samanta A, Li B, Song X, Bembas K, Zhang G, Katsumata M, Saouaf SJ, Wang Q, Hancock WW, Shen Y, Greene MI. TGFbeta and IL-6 signals modulate chromatin binding and promoter occupancy by acetylated FOXP3. Proc Natl Acad Sci USA. 2008;105:14023-7.
37. Kehrl JH, Roberts AB, Wakefield LM, Jakowlew S, Sporn MB, Fauci AS. Transforming growth factor beta is an important immunomodulatory protein for human B lymphocytes. J Immunol. 1986;137:3855-60. (Pubitemid 17215314)
38. Imai Y, Yamakawa M. Morphology, function and pathology of follicular dendritic cells. Path Int. 1996;46(11):807-33. (Pubitemid 26408673)
39. Assoian RK, Fleurdelys BE, Stevenson HC, Miller PJ, Madtes DK, Raines EW, Ross R, Sporn MB. Expression and secretion of type beta transforming growth factor by activated human macrophages. Proc Natl Acad Sci USA. 1987;84:6020-4. (Pubitemid 17140174)
40. Liu Y-J, Xu J, de Bouteiller O, de Saint-Vis B, Lebecque S, Banchereau J, Moore KW. Follicular dendritic cells specifically express the long CR2/CD21 isoform. J Exp Med. 1977;185:165-70.
41. Macallan DC, Wallace DL, Irvine AJ, Asquith B, Worth A, Ghattas H, Zhang Y, Griffin GE, Tough DF, Beverley PC. Rapid turnover of T cells in acute infectious mononucleosis. Eur J Immunol. 2003;33:2655-65. (Pubitemid 37337131)
42. Pudney VA, Leese AM, Rickinson AB, Hislop AD. CD8+ immunodominance among Epstein-Barr virus lytic cycle antigens directly reflects the efficiency of antigen presentation in lytically infected cells. J Exp Med. 2005;201:349-60. (Pubitemid 40229410)
43. Kinter AL, Hennessey M, Bell A, Kern S, Lin Y, Daucher M, Planta M, McGlaughlin M, Jackson R, Ziegler SF, Fauci AS. CD25(+)CD4(+) regulatory T cells from the peripheral blood of asymptomatic HIV-infected individuals regulate CD4(+) and CD8(+) HIV-specific T cell immune responses in vitro and are associated with favorable clinical markers of disease status. J Exp Med. 2004;200:331-43. (Pubitemid 39031252)
44. Rushbrook SM, Ward SM, Unitt E, Vowler SL, Lucas M, Klenerman P, Alexander GJ. Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection. J Virol. 2005;79:7852-9. (Pubitemid 40756820)
45. Xu D, Fu J, Jin L, Zhang H, Zhou C, Zou Z, Zhao JM, Zhang B, Shi M, Ding X, et al. Circulating and liver resident CD4+CD25+ regulatory T cells actively influence the antiviral immune response and disease progression in patients with hepatitis B. J Immunol. 2006;177:739-47. (Pubitemid 43939189)