메뉴 건너뛰기




Volumn 50, Issue 1, 2011, Pages 49-68

On the logic of restrictive recognition of peptide by the T-cell antigen receptor

Author keywords

Alloreactivity; MHC encoded restricting element; Restricted reactivity; Structure function relationships; TCR model

Indexed keywords

BREAKPOINT CLUSTER REGION PROTEIN; CARBOHYDRATE; DNA NUCLEOTIDYLEXOTRANSFERASE; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN; NICOTINAMIDE ADENINE DINUCLEOTIDE; PEPTIDE; PEPTIDE LIBRARY; T LYMPHOCYTE RECEPTOR;

EID: 79955628614     PISSN: 0257277X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12026-010-8173-y     Document Type: Review
Times cited : (27)

References (79)
  • 1
    • 0016318314 scopus 로고
    • Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis
    • Zinkernagel RM, Doherty PC. Immunological surveillance against altered self components by sensitised T lymphocytes in lymphocytic choriomeningitis. Nature. 1974;251:547-8.
    • (1974) Nature , vol.251 , pp. 547-548
    • Zinkernagel, R.M.1    Doherty, P.C.2
  • 2
    • 20444418152 scopus 로고    scopus 로고
    • The tritope model for restrictive recognition of antigen by T-cells: I. What assumptions about structure are needed to explain function?
    • Cohn M. The tritope model for restrictive recognition of antigen by T-cells: I. What assumptions about structure are needed to explain function? Mol Immunol. 2005;42:1419-43.
    • (2005) Mol Immunol , vol.42 , pp. 1419-1443
    • Cohn, M.1
  • 3
    • 0033046292 scopus 로고    scopus 로고
    • The standard model of T-cell receptor function: A critical reassessment
    • DOI 10.1046/j.1365-3083.1999.00569.x
    • Langman RE, Cohn M. The standard model of T-cell receptor function: a critical reassessment. Scand J Immunol. 1999;49:570-7. (Pubitemid 29292518)
    • (1999) Scandinavian Journal of Immunology , vol.49 , Issue.6 , pp. 570-577
    • Langman, R.E.1    Cohn, M.2
  • 4
    • 0017598571 scopus 로고
    • Hypothesis: Why do so many lymphocytes respond to major histocompatibility antigens?
    • Matzinger P, Bevan MJ. Hypothesis: why do so many lymphocytes respond to major histocompatibility antigens? Cell Immunol. 1977;29:1-5.
    • (1977) Cell Immunol , vol.29 , pp. 1-5
    • Matzinger, P.1    Bevan, M.J.2
  • 5
    • 62549102995 scopus 로고    scopus 로고
    • TCR-MHC docking orientation: Natural selection, or thymic selection?
    • Collins EJ, Riddle DS. TCR-MHC docking orientation: natural selection, or thymic selection? Immuol Res. 2008;41:267-94.
    • (2008) Immuol Res , vol.41 , pp. 267-294
    • Collins, E.J.1    Riddle, D.S.2
  • 7
    • 0036631247 scopus 로고    scopus 로고
    • The immune system: A weapon of mass destruction invented by evolution to even the odds during the war of the DNAs
    • DOI 10.1034/j.1600-065X.2002.18504.x
    • Cohn M. The immune system: a weapon of mass destruction invented by evolution to even the odds during the war of the DNAs. Immunol Rev. 2002;185:24-38. (Pubitemid 34994928)
    • (2002) Immunological Reviews , vol.185 , pp. 24-38
    • Cohn, M.1
  • 8
    • 26044481694 scopus 로고    scopus 로고
    • What are the commonalities governing the behavior of humoral immune recognitive repertoires?
    • Cohn M. What are the commonalities governing the behavior of humoral immune recognitive repertoires? Dev Comp Immunol. 2006;30:19-42.
    • (2006) Dev Comp Immunol , vol.30 , pp. 19-42
    • Cohn, M.1
  • 9
    • 42649112362 scopus 로고    scopus 로고
    • Evolutionarily conserved amino acids that control TCR-MHC interaction
    • DOI 10.1146/annurev.immunol.26.021607.090421
    • Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu Rev Immunol. 2008;26:171-203. (Pubitemid 351600374)
    • (2008) Annual Review of Immunology , vol.26 , pp. 171-203
    • Marrack, P.1    Scott-Browne, J.P.2    Dai, S.3    Gapin, L.4    Kappler, J.W.5
  • 10
    • 33845665456 scopus 로고    scopus 로고
    • On a key postulate of T-cell receptor restrictive function: The V-gene loci act as a single pool encoding recognition of the polymorphic alleles of the species major histocompatibility complex
    • DOI 10.1111/j.1365-2567.2006.02501.x
    • Cohn M. On a key postulate of TCR restrictive function: the V-gene loci act as a single pool encoding recognition of the polymorphic alleles of the species MHC. Immunology. 2007;120:140-2. (Pubitemid 44950479)
    • (2006) Immunology , vol.120 , Issue.1 , pp. 140-142
    • Cohn, M.1
  • 11
    • 0037373993 scopus 로고    scopus 로고
    • Tritope model of restrictive recognition by the TCR
    • DOI 10.1016/S1471-4906(03)00021-8
    • Cohn M. The Tritope model of restrictive recognition by the TCR. Trends Immunol. 2003;24:127-31. (Pubitemid 36263096)
    • (2003) Trends in Immunology , vol.24 , Issue.3 , pp. 127-131
    • Cohn, M.1
  • 12
    • 22744441535 scopus 로고    scopus 로고
    • How the T cell repertoire becomes peptide and MHC specific
    • DOI 10.1016/j.cell.2005.05.013, PII S0092867405004599
    • Huseby ES, White J, Crawford F, Vass T, Becker D, Pinilla C, Marrack P, Kappler JW. How the T cell repertoire becomes peptide and MHC specific. Cell. 2005;122:247-60. (Pubitemid 41032988)
    • (2005) Cell , vol.122 , Issue.2 , pp. 247-260
    • Huseby, E.S.1    White, J.2    Crawford, F.3    Vass, T.4    Becker, D.5    Pinilla, C.6    Marrack, P.7    Kappler, J.W.8
  • 13
    • 1842784950 scopus 로고    scopus 로고
    • An alternative to current thinking about positive selection, negative selection and activation of T-cells
    • Cohn M. An alternative to current thinking about positive selection, negative selection and activation of T-cells. Immunology. 2004;111:1-6.
    • (2004) Immunology , vol.111 , pp. 1-6
    • Cohn, M.1
  • 14
    • 33645021142 scopus 로고    scopus 로고
    • On the logic of positive selection
    • Cohn M. On the logic of positive selection. Immunology. 2006;117:452-3.
    • (2006) Immunology , vol.117 , pp. 452-453
    • Cohn, M.1
  • 15
    • 0026004894 scopus 로고
    • Alloreactive cytotoxic T cells recognize MHC Class I antigen without peptide specificity
    • Müllbacher A, Hill AB, Blanden RV, Cowden WB, King NJC. Alloreactive cytotoxic T cells recognize MHC Class I antigen without peptide specificity. J Immunol. 1991;147:1765-71.
    • (1991) J Immunol , vol.147 , pp. 1765-1771
    • Müllbacher, A.1    Hill, A.B.2    Blanden, R.V.3    Cowden, W.B.4    King, N.J.C.5
  • 17
    • 34848917274 scopus 로고    scopus 로고
    • The tritope model for restrictive recognition of antigen by T-cells: II. Implications for ontogeny, evolution and physiology
    • Cohn M. The tritope model for restrictive recognition of antigen by T-cells: II. Implications for ontogeny, evolution and physiology. Mol Immunol. 2008;45:632-52.
    • (2008) Mol Immunol , vol.45 , pp. 632-652
    • Cohn, M.1
  • 19
    • 61349149901 scopus 로고    scopus 로고
    • Affinity threshold for thymic selection through a T-cell receptor - Co-receptor zipper
    • Palmer E, Naeher D. Affinity threshold for thymic selection through a T-cell receptor - co-receptor zipper. Nat Rev Immunol. 2009;9:207-13.
    • (2009) Nat Rev Immunol , vol.9 , pp. 207-213
    • Palmer, E.1    Naeher, D.2
  • 21
    • 77953449167 scopus 로고    scopus 로고
    • A thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo
    • Alves NL, Huntington ND, Mention J-J, Richard-Le Goff O, Di Santo JP. A thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo. J Immunol. 2010;184:5949-53.
    • (2010) J Immunol , vol.184 , pp. 5949-5953
    • Alves, N.L.1    Huntington, N.D.2    Mention, J.-J.3    Richard-Le Goff, O.4    Di Santo, J.P.5
  • 22
    • 33745862749 scopus 로고    scopus 로고
    • The clone size of peripheral CD8 T cells is regulated by TCR promiscuity
    • DOI 10.1084/jem.20052174
    • Hao Y, Legrand N, Freitas AA. The clone size of peripheral CD8 T cells is regulated by TCR promiscuity. J Exp Med. 2006;203:1643-9. (Pubitemid 44036268)
    • (2006) Journal of Experimental Medicine , vol.203 , Issue.7 , pp. 1643-1649
    • Hao, Y.1    Legrand, N.2    Freitas, A.A.3
  • 23
    • 70450240779 scopus 로고    scopus 로고
    • dto generate T cell specificity directed against their respective bound peptides
    • d to generate T cell specificity directed against their respective bound peptides. J Biol Chem. 2009;284:32551-61.
    • (2009) J Biol Chem , vol.284 , pp. 32551-32561
    • Bowerman, N.A.1    Colf, L.A.2    Garcia, K.C.3    Kranz, D.M.4
  • 24
    • 2942716814 scopus 로고    scopus 로고
    • TCR-MHC/peptide interactions: Kissing-cousins or a shotgun wedding?
    • Huseby ES, Kappler JW, Marrack P. TCR-MHC/peptide interactions: kissing-cousins or a shotgun wedding? Eur J Immunol. 2004;34:1243-50.
    • (2004) Eur J Immunol , vol.34 , pp. 1243-1250
    • Huseby, E.S.1    Kappler, J.W.2    Marrack, P.3
  • 25
    • 0001937634 scopus 로고
    • The somatic generation of immune recognition
    • Jerne NK. The somatic generation of immune recognition. Eur J Immunol. 1971;1:1-9.
    • (1971) Eur J Immunol , vol.1 , pp. 1-9
    • Jerne, N.K.1
  • 27
    • 77956786100 scopus 로고
    • Generation of antibody diversity and self tolerance
    • Smith RT, Landy M, editors. Augusta: Academic Press
    • Jerne NK. Generation of antibody diversity and self tolerance. In: Smith RT, Landy M, editors. Immune surveillance. Augusta: Academic Press; 1970. p. 343-436.
    • (1970) Immune Surveillance , pp. 343-436
    • Jerne, N.K.1
  • 29
    • 0026690960 scopus 로고
    • The self-nonself discrimination: Reconstructing a cabbage from sauerkraut
    • Cohn M. The self-nonself discrimination: reconstructing a cabbage from sauerkraut. Res Immunol. 1992;143:323-34.
    • (1992) Res Immunol , vol.143 , pp. 323-334
    • Cohn, M.1
  • 30
    • 0028129508 scopus 로고
    • Major histocompatibility complex class I allele-specific peptide libraries: Identification of peptides that mimic an H-Y T cell epitope
    • Gavin MA, Dere B, Grandea AG, Hogquist KA, Bevan MJ. Major histocompatibility complex class I allele-specific peptide libraries: identification of peptides that mimic an H-Y T cell epitope. Eur J Immunol. 1994;24:2124-33. (Pubitemid 24276545)
    • (1994) European Journal of Immunology , vol.24 , Issue.9 , pp. 2124-2133
    • Gavin, M.A.1    Dere, B.2    Grandea III, A.G.3    Hogquist, K.A.4    Bevan, M.J.5
  • 31
    • 0029552310 scopus 로고
    • Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire
    • DOI 10.1016/1074-7613(95)90068-3
    • Gavin MA, Bevan JJ. Increased peptide promiscuity provides a rationale for the lack of N regions in the neonatal T cell repertoire. Immunity. 1995;3:793-800. (Pubitemid 26092192)
    • (1995) Immunity , vol.3 , Issue.6 , pp. 793-800
    • Gavin, M.A.1    Bevan, M.J.2
  • 33
    • 33750113432 scopus 로고    scopus 로고
    • Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide
    • DOI 10.1038/ni1401, PII NI1401
    • Huseby ES, Crawford F, White AJ, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat Immunol. 2006;7:1191-9. (Pubitemid 44594315)
    • (2006) Nature Immunology , vol.7 , Issue.11 , pp. 1191-1199
    • Huseby, E.S.1    Crawford, F.2    White, J.3    Marrack, P.4    Kappler, J.W.5
  • 34
    • 34848813147 scopus 로고    scopus 로고
    • Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains
    • DOI 10.1016/j.molimm.2006.03.025, PII S0161589007006219, Theories and Modelling of T Cell Behaviour
    • Huseby ES, Kappler JW, Marrack P. Thymic selection stifles TCR reactivity with the main chain structure of MHC and forces interactions with the peptide side chains. Mol Immunol. 2008;45:599-606. (Pubitemid 47498587)
    • (2008) Molecular Immunology , vol.45 , Issue.3 , pp. 599-606
    • Huseby, E.S.1    Kappler, J.W.2    Marrack, P.3
  • 37
    • 0030064106 scopus 로고    scopus 로고
    • Antigen receptor 'capacity' and the sensitivity of self-tolerance
    • DOI 10.1016/0167-5699(96)80565-2
    • Nemazee D. Antigen receptor "capacity" and the sensitivity of self-tolerance. Immunol Today. 1996;17:25-9. (Pubitemid 26019254)
    • (1996) Immunology Today , vol.17 , Issue.1 , pp. 25-29
    • Nemazee, D.1
  • 38
    • 10644222102 scopus 로고    scopus 로고
    • Degeneracy, mimicry and crossreactivity in immune recognition
    • DOI 10.1016/j.molimm.2004.09.010, PII S016158900400344X
    • Cohn M. Degeneracy, mimicry and crossreactivity in immune recognition. Mol Immunol. 2005;42:651-5. (Pubitemid 39655942)
    • (2005) Molecular Immunology , vol.42 , Issue.5 , pp. 651-655
    • Cohn, M.1
  • 39
    • 42249105265 scopus 로고    scopus 로고
    • An in depth analysis of the concept of "polyspecificity" assumed to characterize TCR/BCR recognition
    • Cohn M. An in depth analysis of the concept of " polyspecificity" assumed to characterize TCR/BCR recognition. Immunol Res. 2008;40:128-47.
    • (2008) Immunol Res , vol.40 , pp. 128-147
    • Cohn, M.1
  • 40
    • 0023724209 scopus 로고
    • Positive and negative selection of an antigen receptor on T cells in transgenic mice
    • DOI 10.1038/336073a0
    • Sha WC, Nelson CA, Newberry RD, Kranz DM, Russell JH, Loh DY. Positive and negative selection of an antigen receptor on T cells in transgenic mice. Nature. 1988;336:73-6. (Pubitemid 18262137)
    • (1988) Nature , vol.336 , Issue.6194 , pp. 73-76
    • Sha, W.C.1    Nelson, C.A.2    Newberry, R.D.3    Kranz, D.M.4    Russell, J.H.5    Loh, D.Y.6
  • 42
    • 0037220526 scopus 로고    scopus 로고
    • Recognition of a specific self-peptide: Self-MHC class II complex is critical for positive selection of thymocytes expressing the D10 TCR
    • Dao T, Blander JM, Sant'Angelo DB. Recognition of a specific self-peptide: Self-MHC Class II complex is critical for positive selection of thymocytes expressing the D10-TCR. J Immunol. 2003;170:48-54. (Pubitemid 36026122)
    • (2003) Journal of Immunology , vol.170 , Issue.1 , pp. 48-54
    • Dao, T.1    Blander, J.M.2    Sant'Angelo, D.B.3
  • 47
    • 0034192085 scopus 로고    scopus 로고
    • 52-68 structurally related self-peptide(s) in I-Ealpha-deficient mice
    • Viret C, Janeway CA. Functional and phenotypic evidence for presentation of E alpha 52-68 structurally related self-peptide(s) in I-E alpha-deficient mice. J Immunol. 2000;164:4627-34. (Pubitemid 30238061)
    • (2000) Journal of Immunology , vol.164 , Issue.9 , pp. 4627-4634
    • Viret, C.1    Janeway Jr., C.A.2
  • 48
    • 0024279866 scopus 로고
    • Compartmentalization of MHC Class II gene expression in transgenic mice
    • Ewijk WV, Ron Y, Monaco J, et al. Compartmentalization of MHC Class II gene expression in transgenic mice. Cell. 1988;53:357-70.
    • (1988) Cell , vol.53 , pp. 357-370
    • Ewijk, W.V.1    Ron, Y.2    Monaco, J.3
  • 49
    • 0027457002 scopus 로고
    • The IE allogeneic response of T cells from C57B1/6 mice is associated with genes of the TCRa locus
    • Rubin B, Gouaillard C, Weideranders G, Kuklmann J. The IE allogeneic response of T cells from C57B1/6 mice is associated with genes of the TCRa locus. Scand J Immunol. 1993;37:388-97.
    • (1993) Scand J Immunol , vol.37 , pp. 388-397
    • Rubin, B.1    Gouaillard, C.2    Weideranders, G.3    Kuklmann, J.4
  • 51
    • 0028232578 scopus 로고
    • The minimal polymorphism of Class II Ealpha chains is not due to the functional neutrality of mutations
    • Zy-Tmg E, Chu C, Carswell C, Cole BC, Jones PP. The minimal polymorphism of Class II Ealpha chains is not due to the functional neutrality of mutations. Genetics. 1994;40:9-20.
    • (1994) Genetics , vol.40 , pp. 9-20
    • Zy-Tmg, E.1    Chu, C.2    Carswell, C.3    Cole, B.C.4    Jones, P.P.5
  • 53
    • 67449149805 scopus 로고    scopus 로고
    • Cutting edge: Highly alloreactive dual TCR T cells play a dominant role in graft-versus-host disease
    • Morris GP, Allen PM. Cutting edge: highly alloreactive dual TCR T cells play a dominant role in graft-versus-host disease. J Immunol. 2009;182:6639-43.
    • (2009) J Immunol , vol.182 , pp. 6639-6643
    • Morris, G.P.1    Allen, P.M.2
  • 55
    • 0032055548 scopus 로고    scopus 로고
    • + T cell alloresponse using altered peptide ligands
    • + T cell alloresponse using altered peptide ligands. J Immunol. 1998;160:3244-50.
    • (1998) J Immunol , vol.160 , pp. 3244-3250
    • Daniel, C.1    Grakoui, A.2    Allen, P.A.3
  • 56
    • 0032076237 scopus 로고    scopus 로고
    • A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR
    • DOI 10.1016/S1074-7613(00)80559-2
    • Daniel C, Horvath S, Allen PM. A basis for alloreactivity: MHC helical residues broaden peptide recognition by the TCR. Immunity. 1998;8:543-52. (Pubitemid 28264745)
    • (1998) Immunity , vol.8 , Issue.5 , pp. 543-552
    • Daniel, C.1    Horvath, S.2    Allen, P.M.3
  • 57
    • 0035122708 scopus 로고    scopus 로고
    • The shaping of the T cell repertoire
    • DOI 10.1016/S1074-7613(01)00086-3
    • Correia-Neves M, Waltzinger C, Mathis D, Benoist C. The shaping of the T cell repertoire. Immunity. 2001;14:21-32. (Pubitemid 32144684)
    • (2001) Immunity , vol.14 , Issue.1 , pp. 21-32
    • Correia-Neves, M.1    Waltzinger, C.2    Mathis, D.3    Benoist, C.4
  • 58
    • 0023649239 scopus 로고
    • The molecular basis of alloreactivity in antigen-specific, major histocompatibility complex-restricted T cell clones
    • Matis LA, Sorger SB, McElligott DL, Fink PJ, Hedrick SM. The molecular basis of alloreactivity in antigen-specific, major histocompatibility complex-restricted T cell clones. Cell. 1987;51:59-69.
    • (1987) Cell , vol.51 , pp. 59-69
    • Matis, L.A.1    Sorger, S.B.2    McElligott, D.L.3    Fink, P.J.4    Hedrick, S.M.5
  • 59
    • 0025191160 scopus 로고
    • Expression of identical VαVβ gene pairs by IE-alloreactive and IE-restricted, antigen-specific T cells from MHC disparate mice. Evidence for thymic selection of V(D)J combinations
    • Nakajima PB, Betz CJ, Hansburg D. Expression of identical VαVβ gene pairs by IE-alloreactive and IE-restricted, antigenspecific T cells from MHC disparate mice. J Immunol. 1990;144:348-57. (Pubitemid 20030500)
    • (1990) Journal of Immunology , vol.144 , Issue.1 , pp. 348-357
    • Nakajima, P.B.1    Betz, C.J.2    Hansburg, D.3
  • 60
    • 85053180227 scopus 로고    scopus 로고
    • Distinguishing the tritope from the interaction antigen models
    • Cohn M. Distinguishing the tritope from the interaction antigen models. Trends Immunol. 2004;25:8-9.
    • (2004) Trends Immunol , vol.25 , pp. 8-9
    • Cohn, M.1
  • 61
    • 31144451571 scopus 로고    scopus 로고
    • + lineage commitment
    • Eshima K, Suzuki H, Shinohara N. Cross-positive selection of thymocytes expressing a single TCR by multiple major histocompatibility complex molecules of both classes: implications for CD4+ versus CD8+ lineage commitment. J Immunol. 2006;176:1628-36. (Pubitemid 43134307)
    • (2006) Journal of Immunology , vol.176 , Issue.3 , pp. 1628-1636
    • Eshima, K.1    Suzuki, H.2    Shinohara, N.3
  • 64
    • 0027452074 scopus 로고
    • Mice lacking TdT: Mature animals with an immature lymphocyte repertoire
    • Gilfillan S, Dierich A, Lemeur M, Benoist C, Mathis D. Mice lacking TdT: mature animals with an immature lymphocyte repertoire. Science. 1993;261:1175-8. (Pubitemid 23300885)
    • (1993) Science , vol.261 , Issue.5125 , pp. 1175-1178
    • Gilfillan, S.1    Dierich, A.2    Lemeur, M.3    Benoist, C.4    Mathis, D.5
  • 65
    • 0027369562 scopus 로고
    • Lack of N regions in antigen receptor variable region genes of TdT- Deficient lymphocytes
    • Komori T, Okada A, Stewart V, Alt FW. Lack of N regions in antigen receptor variable region genes of TdT-deficient lymphocytes. Science. 1993;261:1171-5. (Pubitemid 23300884)
    • (1993) Science , vol.261 , Issue.5125 , pp. 1171-1175
    • Komori, T.1    Okada, A.2    Stewart, V.3    Alt, F.W.4
  • 67
    • 0027973205 scopus 로고
    • More efficient positive selection of thymocytes in mice lacking terminal deoxynucleotidyl transferase
    • Gilfillan S, Waltzinger C, Benoist C, Mathis D. More efficient positive selection of thymocytes in mice lacking terminal deoxynucleotidyl transferase. Int Immunol. 1994;6:1681-6. (Pubitemid 24357880)
    • (1994) International Immunology , vol.6 , Issue.11 , pp. 1681-1686
    • Gilfillan, S.1    Waltzinger, C.2    Benoist, C.3    Mathis, D.4
  • 68
    • 50549088455 scopus 로고    scopus 로고
    • A hypothesis accounting for the paradoxical expression of the D gene segment in the BCR and the TCR
    • Cohn M. A hypothesis accounting for the paradoxical expression of the D gene segment in the BCR and the TCR. Eur J Immunol. 2008;38:1779-87.
    • (2008) Eur J Immunol , vol.38 , pp. 1779-1787
    • Cohn, M.1
  • 69
    • 0017908778 scopus 로고
    • Cell-mediated immunity and the major histocompatibility complex
    • Langman RE. Cell-mediated immunity and the major histocompatibility complex. Rev Physiol Biochem Pharmacol. 1978;81:1-37.
    • (1978) Rev Physiol Biochem Pharmacol , vol.81 , pp. 1-37
    • Langman, R.E.1
  • 70
    • 0018134884 scopus 로고
    • T-cell inhibition of humoral responsiveness. II. Theory on the role of restrictive recognition in immune regulation
    • Cohn M, Epstein R. T-cell inhibition of humoral responsiveness. II. Theory on the role of restrictive recognition in immune regulation. Cellular Immunol. 1978;39:125-53.
    • (1978) Cellular Immunol , vol.39 , pp. 125-153
    • Cohn, M.1    Epstein, R.2
  • 71
    • 34548128306 scopus 로고    scopus 로고
    • Structural evidence for a germline-encoded T cell receptor - Major histocompatibility complex interaction 'codon'
    • Feng D, Bond CJ, Ely LI, Maynard J, Garcia KC. Structural evidence for a germline-encoded T cell receptor - major histocompatibility complex interaction 'codon'. Nat. Immunol. 2007;8:975-83.
    • (2007) Nat. Immunol , vol.8 , pp. 975-983
    • Feng, D.1    Bond, C.J.2    Ely, L.I.3    Maynard, J.4    Garcia, K.C.5
  • 72
    • 58649114309 scopus 로고    scopus 로고
    • The molecular basis of TCR germline bias for MHC is surprisingly simple
    • Garcia KC, Adams JJ, Feng D, Ely LK. The molecular basis of TCR germline bias for MHC is surprisingly simple. Nat Immunol. 2009;10:143-7.
    • (2009) Nat Immunol , vol.10 , pp. 143-147
    • Garcia, K.C.1    Adams, J.J.2    Feng, D.3    Ely, L.K.4
  • 73
    • 43449097191 scopus 로고    scopus 로고
    • What does the T-cell receptor recognize when it docks on an MHC-encoded restricting element?
    • Cohn M. What does the T-cell receptor recognize when it docks on an MHC-encoded restricting element? Mol Immunol. 2008;45:3264-7.
    • (2008) Mol Immunol , vol.45 , pp. 3264-3267
    • Cohn, M.1
  • 74
    • 54049111388 scopus 로고    scopus 로고
    • Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes
    • Armstrong KM, Piepenbrink KH, Baker BM. Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes. Biochem J. 2008;415:183-96.
    • (2008) Biochem J , vol.415 , pp. 183-196
    • Armstrong, K.M.1    Piepenbrink, K.H.2    Baker, B.M.3
  • 79
    • 0024216840 scopus 로고
    • Asymmetry in the recognition of antigen: Self class II MHC and non-self class II MHC molecules by the same T-cell receptor
    • Portoles P, Rojo JJ, Janeway CA Jr. Asymmetry in the recognition of antigen: self class II MHC and non-self class II MHC molecules by the same T-cell receptor. J Mol Cell Immunol. 1989;4:129-37. (Pubitemid 19096560)
    • (1988) Journal of Molecular and Cellular Immunology , vol.4 , Issue.3 , pp. 129-137
    • Portoles, P.1    Rojo, J.M.2    Janeway Jr., C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.