Site-specific radical formation in DNA induced by Cu(II)-H 2O2 oxidizing system, using ESR, immuno-spin trapping, LC-MS, and MS/MS

Free Radical Biology and Medicine

Volumn 50, Issue 11, 2011, Pages 1536-1545

  Bhattacharjee, Suchandra ^a   Deterding, Leesa J ^a   Chatterjee, Saurabh ^a   Jiang, Jinjie ^a   Ehrenshaft, Marilyn ^a   Lardinois, Olivier ^a   Ramirez, Dario C ^b   Tomer, Kenneth B ^a   Mason, Ronald P ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Cells; Copper; Detect; DNA radicals; ESR; Free radicals; Identify; IST; LC MS MS; Nucleosides; Spin trapping

Indexed keywords

5,5 DIMETHYL 1 PYRROLINE 1 OXIDE; CELL DNA; COPPER CHLORIDE; COPPER ION; DEOXYADENOSINE; FREE RADICAL; HYDROGEN PEROXIDE; NITRONE;

ANIMAL CELL; ARTICLE; CALF (BOVINE); CELL STRAIN; CELL STRAIN RAW 264 7; CONTROLLED STUDY; DNA DAMAGE; ELECTRON SPIN RESONANCE; ELECTROSPRAY MASS SPECTROMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; SPIN TRAPPING; TANDEM MASS SPECTROMETRY; THYMUS;

ANIMALS; CATTLE; CELL LINE; COPPER; DNA; DNA ADDUCTS; DNA DAMAGE; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; HYDROGEN PEROXIDE; MASS SPECTROMETRY; MICE; NITROGEN OXIDES; OXIDATION-REDUCTION; SPIN TRAPPING;

EID: 79955623975     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.02.034     Document Type: Article

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