Proteomic and metabolomic analysis of H2O2-induced premature senescent human mesenchymal stem cells

Experimental Gerontology

Volumn 46, Issue 6, 2011, Pages 500-510

  Kim, Ji Soo ^a   Kim, Eui Jin ^a   Kim, Hyun Jung ^a   Yang, Ji Young ^b   Hwang, Geum Sook ^b   Kim, Chan Wha ^a  

^a Korea University   (South Korea)

^b Korea Basic Science Institute (KBSI)   (South Korea)

Author keywords

Cellular senescence; Mesenchymal stem cells; Metabolomics; Proteomics; Reactive oxygen species

Indexed keywords

BETA ACTIN; CELL PROTEIN; CHOLINE; ENOYL COENZYME A HYDRATASE; HYDROGEN PEROXIDE; LEUCINE; LIPOCORTIN 2; MUTANT PROTEIN; MYOSIN LIGHT CHAIN 2; PROSOMAL PROTEIN P30 33K; UNCLASSIFIED DRUG;

ARTICLE; CELL AGING; CELL METABOLISM; CELL STRESS; CELL TYPE; CELLULAR STRESS RESPONSE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; METABOLOMICS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; PROTON NUCLEAR MAGNETIC RESONANCE; SENESCENCE; STRESS INDUCED PREMATURE SENESCENCE; TIME OF FLIGHT MASS SPECTROMETRY; UPREGULATION;

ANNEXIN A2; CELL AGING; CELL PROLIFERATION; CELLS, CULTURED; CHOLINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GLYCINE; HUMANS; HYDROGEN PEROXIDE; LEUCINE; MESENCHYMAL STEM CELLS; METABOLOMICS; PROLINE; PROTEOMICS; REACTIVE OXYGEN SPECIES;

EID: 79955613626     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exger.2011.02.012     Document Type: Article

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