Yeast PAS kinase coordinates glucose partitioning in response to metabolic and cell integrity signaling

EMBO Journal

Volumn 26, Issue 23, 2007, Pages 4824-4830

  Grose, Julianne H ^a   Smith, Tammy L ^a   Sabic, Hana ^a   Rutter, Jared ^a  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Cell integrity signaling; Glucose metabolism; Kinase regulation

Indexed keywords

ENZYME; GLUCOSE; PSK1 PROTEIN; PSK2 PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL STRESS; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; METABOLISM; NONHUMAN; NUTRIENT; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST;

CARBON; ENZYME ACTIVATION; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; GLUCOSE; HOMEOSTASIS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; SACCHAROMYCES CEREVISIAE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; UTP-GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE;

MAMMALIA; SACCHAROMYCES CEREVISIAE;

EID: 36549018583     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601914     Document Type: Article

References (26)

1. Amezcua CA, Harper SM, Rutter J, Gardner KH (2002) Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation. Structure (Cambridge) 10: 1349-1361
2. Bickle M, Delley PA, Schmidt A, Hall MN (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. EMBO J 17: 2235-2245
3. Bisson LF (1988) High-affinity glucose transport in Saccharomyces cerevisiae is under general glucose repression control. J Bacteriol 170: 4838-4845
4. Carlson M (1999) Glucose repression in yeast. Curr Opin Microbiol 2: 202-207
5. da Silva Xavier G, Rutter J, Rutter GA (2004) Involvement of Per-Arnt-Sim (PAS) kinase in the stimulation of preproinsulin and pancreatic duodenum homeobox 1 gene expression by glucose. Proc Natl Acad Sci USA 101: 8319-8324; e-pub ahead of print 2004 May 8317
6. Eurich DT, Majumdar SR, McAlister FA, Tsuyuki RT, Johnson JA (2005) Improved clinical outcomes associated with metformin in patients with diabetes and heart failure. Diabetes Care 28: 2345-2351
7. Fryer LG, Carling D (2005) AMP-activated protein kinase and the metabolic syndrome. Biochem Soc Trans 33: 362-366
8. Hao H, Cardon CM, Swiatek W, Cooksey RC, Smith TL, Boudina S, Wenger RH, Abel ED, McClain DA, Rutter J (2007) PAS kinase is required for normal cellular energy balance. Proc Natl Acad Sci USA 104: 15466-15471
9. Hardie DG, Carling D, Carlson M (1998) The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell? Ann Rev Biochem 67: 821-855
10. Kamada Y, Jung US, Piotrowski J, Levin DE (1995) The protein kinase C-activated MAP kinase pathway of Saccharomyces cerevisiae mediates a novel aspect of the heat shock response. Genes Dev 9: 1559-1571
11. Klis FM, Boorsma A, De Groot PW (2006) Cell wall construction in Saccharomyces cerevisiae. Yeast 23: 185-202
12. Levin DE (2005) Cell wall integrity signaling in Saccharomyces cerevisiae. Microbiol Mol Biol Rev 69: 262-291
13. Lindsley JE, Rutter J (2004) Nutrient sensing and metabolic decisions. Comp Biochem Physiol B Biochem Mol Biol 139: 543-559
14. Rajavel M, Philip B, Buehrer BM, Errede B, Levin DE (1999) Mid2 is a putative sensor for cell integrity signaling in Saccharomyces cerevisiae. Mol Cell Biol 19: 3969-3976
15. Rutter J, Michnoff CH, Harper SM, Gardner KH, McKnight SL (2001) PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase. Proc Natl Acad Sci USA 98: 8991-8996
16. Rutter J, Probst BL, McKnight SL (2002) Coordinate regulation of sugar flux and translation by PAS kinase. Cell 111: 17-28
17. Sanz P, Alms GR, Haystead TA, Carlson M (2000) Regulatory interactions between the Reg1-Glc7 protein phosphatase and the Snf1 protein kinase. Mol Cell Biol 20: 1321-1328
18. Sarbassov dos D, Ali SM, Sabatini DM (2005) Growing roles for the mTOR pathway. Curr Opin Cell Biol 17: 596-603; e-pub ahead of print 2005 October 2013
19. Schmelzle T, Hall MN (2000) TOR, a central controller of cell growth. Cell 103: 253-262
20. Sekiya-Kawasaki M, Abe M, Saka A, Watanabe D, Kono K, Minemura Asakawa M, Ishihara S, Watanabe T, Ohya Y (2002) Dissection of upstream regulatory components of the Rho1p effector, 1,3-beta-glucan synthase, in Saccharomyces cerevisiae. Genetics 162: 663-676
21. Sherman F (1991) Getting started with yeast. In Guide to Yeast Genetics and Molecular Biology, Fink GR (ed), pp 3-21. San Diego, CA: Academic Press
22. Smith TL, Rutter J (2007) Regulated glucose partioning by PAS kinase. Mol Cell 26: 491-499
23. Taylor BL, Zhulin IB (1999) PAS domains: internal sensors of oxygen, redox potential, and light. Microbiol Mol Biol Rev (Washington, DC) 63: 479-506
24. Thomas BJ, Rothstein R (1989) Elevated recombination rates in transcriptionally active DNA. Cell 56: 619-630
25. Tu J, Carlson M (1995) REG1 binds to protein phosphatase type 1 and regulates glucose repression in Saccharomyces cerevisiae. EMBO J 14: 5939-5946
26. Verna J, Lodder A, Lee K, Vagts A, Ballester R (1997) A family of genes required for maintenance of cell wall integrity and for the stress response in Saccharomyces cerevisiae. Proc Natl Acad Sci USA 94: 13804-13809