One-pot synthesis of hybrid macrocyclic pentamers with variable functionalizations around the periphery

Organic Letters

Volumn 13, Issue 9, 2011, Pages 2270-2273

  Qin, Bo ^a   Sun, Chang ^a   Liu, Ying ^a   Shen, Jie ^a   Ye, Ruijuan ^a   Zhu, Jia ^b   Duan, Xin Fang ^b   Zeng, Huaqiang ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b BEIJING NORMAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MACROCYCLIC COMPOUND;

ARTICLE; CHEMICAL STRUCTURE; CYCLIZATION; HYDROGEN BOND; SYNTHESIS;

CYCLIZATION; HYDROGEN BONDING; MACROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE;

EID: 79955607385     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol200538d     Document Type: Article

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55. 1H NMR only allows us to confidently conclude that it does contain small amounts of intermediate amino acids (e.g., dimer amino acid, trimer amino acid, and tetra amino acid) and does not contain any unreacted starting monomer amino acid such as 1a. Other than these, the identity of any other remaining is unknown to us.
56. Please note that pentamer 1 stains much less intensely when compared to pentamers 2 and 2b - 2g.