A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model

Arthritis and Rheumatism

Volumn 63, Issue 5, 2011, Pages 1301-1311

  Abe, Koichiro ^a,b   Fuchs, Helmut ^b   Boersma, Auke ^b   Hans, Wolfgang ^b   Yu, Philipp ^c   Kalaydjiev, Svetoslav ^b,d   Klaften, Matthias ^b   Adler, Thure ^b,d   Calzada Wack, Julia ^b   Mossbrugger, Ilona ^b   Rathkolb, Birgit ^b,e   Rozman, Jan ^d   Prehn, Cornelia ^b   Maraslioglu, Miriam ^c   Kametani, Yoshie ^f   Shimada, Shin ^f   Adamski, Jerzy ^b   Busch, Dirk H ^b,d   Esposito, Irene ^b   Klingenspor, Martin ^d   Wolf, Eckhard ^b,e   Wurst, Wolfgang ^b,d,g,h   Gailus Durner, Valerie ^b   Katan, Matilda ⁱ   Marschall, Susan ^b   Soewarto, Dian ^b   Wagner, Sibylle ^b   De Angelis, Martin Hrabě ^b,d   more..

^a TOKAI UNIVERSITY   (Japan)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

^f TOKAI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^g MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^h GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

ⁱ Royal Cancer Hospital   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CHOLESTEROL; ETHYLNITROSOUREA; PHOSPHOLIPASE C GAMMA2; TRIACYLGLYCEROL;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTHRITIS; ARTICLE; BODY COMPOSITION; CALCIUM TRANSPORT; CONTROLLED STUDY; EMBRYO; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; GENE FUNCTION; GENE MAPPING; GENE MUTATION; GENE SEQUENCE; GENETIC SCREENING; HINDLIMB; IN VITRO STUDY; JOINT SWELLING; LYMPHOCYTE; MALE; MALE INFERTILITY; METABOLIC DISORDER; MISSENSE MUTATION; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SPERMATOZOON; SPERMATOZOON MOTILITY; UPREGULATION;

ANIMALS; ARTHRITIS, EXPERIMENTAL; BODY COMPOSITION; ETHYLNITROSOUREA; FLOW CYTOMETRY; INFERTILITY, MALE; MALE; MICE; MICE, MUTANT STRAINS; MUTAGENESIS; MUTATION; PHOSPHOLIPASE C GAMMA; POLYMORPHISM, SINGLE NUCLEOTIDE; SPERM MOTILITY;

EID: 79955567948     PISSN: 00043591     EISSN: 15290131     Source Type: Journal    
DOI: 10.1002/art.30280     Document Type: Article

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