4-fluoropyrrolidine-2-carbonyl fluorides: Useful synthons and their facile preparation with 4-tert-butyl-2,6-dimethylphenylsulfur trifluoride

Journal of Organic Chemistry

Volumn 76, Issue 9, 2011, Pages 3113-3121

  Singh, Rajendra P ^a   Umemoto, Teruo ^a  

^a IM and T Research Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 HYDROXYPROLINES; [CARBONYL; CARBONITRILES; CARBOXAMIDES; DIPEPTIDYL PEPTIDASE; ENANTIOMERICALLY PURE COMPOUNDS; FACILE PREPARATION; HIGH YIELD; MEDICINAL APPLICATIONS; MEDICINAL CHEMISTRY; METHOXY; METHYL ESTERS; STEREOSPECIFIC; SYNTHONS; WEINREB AMIDES;

AMIDES; CARBONYLATION; CARBOXYLATION; ESTERS; FLUORINATION; FLUORINE; FLUORINE COMPOUNDS; HALOGENATION;

CARBONYL COMPOUNDS;

4 FLUOROPYRROLIDINE 2 CARBONYL FLUORIDE; 4 FLUOROPYRROLIDINE 2 CARBOXAMIDE; 4 TERT BUTYL 2,6 DIMETHYLPHENYLSULFUR TRIFLUORIDE; AMIDE; CARBOXYLATE METHYL ESTER; CARBOXYLIC ACID DERIVATIVE; CYANIDE; FLUORIDE; N METHOXY N METHYLCARBOXAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTALLIZATION; DRUG ISOLATION; DRUG SYNTHESIS; ENANTIOMER; FLUORINATION;

HALOGENATION; HYDROCARBONS, FLUORINATED; PYRROLIDINES; STEREOISOMERISM; SUBSTRATE SPECIFICITY;

EID: 79955566466     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo1025783     Document Type: Article

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