Development of a kilogram-scale synthesis of cis-LC15-0133 tartrate, a potent dipeptidyl peptidase IV inhibitor

Organic Process Research and Development

Volumn 12, Issue 4, 2008, Pages 626-631

  Kim, Bong Chan ^a   Kim, Kyu Young ^a   Lee, Hee Bong ^a   Shin, Hyunik ^a  

^a LG Chemical Ltd   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 53849092902     PISSN: 10836160     EISSN: 1520586X     Source Type: Journal    
DOI: 10.1021/op800076r     Document Type: Article

References (16)

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12. 2 or dichloroethane (1.0 L and 500 mL, based on 1.0 L of 75% aqueous oxazolidine) and used after concentration.
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14. 2O = 3:97 containing 0.1% TFA as an eluent at 254 nm; retention times of trans- and cis-1 were 10.9 and 17.8 min, respectively.
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