Mice lacking phosphatase PP2A subunit PR61/B′δ (Ppp2r5d) develop spatially restricted tauopathy by deregulation of CDK5 and GSK3β

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 17, 2011, Pages 6957-6962

  Louis, Justin V ^a   Martens, Ellen ^a   Borghgraef, Peter ^a   Lambrecht, Caroline ^a   Sents, Ward ^a   Longin, Sari ^a   Zwaenepoel, Karen ^a   Pijnenborg, Robert ^a   Landrieu, Isabelle ^b   Lippens, Guy ^b   Ledermann, Birgit ^c   Götz, Jürgen ^d   Van Leuven, Fred ^a   Goris, Jozef ^a   Janssens, Veerle ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITÉ DES SCIENCES ET TECHNOLOGIES DE LILLE   (France)

^c NOVARTIS PHARMA AG   (Switzerland)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

AT180; AT8; Brain stem; Knockout mouse; Transgenic

Indexed keywords

CYCLIN DEPENDENT KINASE 5; EPITOPE; GLYCOGEN SYNTHASE KINASE 3BETA; HOLOENZYME; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN P35; TAU PROTEIN;

ANIMAL TISSUE; ARTICLE; COGNITION; CONTROLLED STUDY; DEPHOSPHORYLATION; ENZYME ACTIVITY; ENZYME REGULATION; ENZYME SUBUNIT; GENE OVEREXPRESSION; HOMEOSTASIS; IMMUNOREACTIVITY; IN VIVO STUDY; MOUSE; NERVOUS TISSUE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN PHOSPHORYLATION; SENSORIMOTOR NEUROPATHY; TAUOPATHY;

ANIMALS; BRAIN; CYCLIN-DEPENDENT KINASE 5; GLYCOGEN SYNTHASE KINASE 3; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; PC12 CELLS; PHOSPHORYLATION; PROTEIN FOLDING; PROTEIN PHOSPHATASE 2; RATS; TAU PROTEINS; TAUOPATHIES;

MUS;

EID: 79955566269     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1018777108     Document Type: Article

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