메뉴 건너뛰기




Volumn 300, Issue 5, 2011, Pages

Regulation of JNK activity in the apoptotic response of intestinal epithelial cells

Author keywords

Camptothecin; Caspase 3; Caspase 9; MEKK4 7

Indexed keywords

ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CAMPTOTHECIN; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOHEXIMIDE; JANUS KINASE; JANUS KINASE 1; JANUS KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA;

EID: 79955556337     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00405.2010     Document Type: Article
Times cited : (19)

References (51)
  • 1
    • 0032958382 scopus 로고    scopus 로고
    • Extracellular signalregulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth
    • Abe MK, Kuo WL, Hershenson MB, Rosner MR. Extracellular signalregulated kinase 7 (ERK7), a novel ERK with a C-terminal domain that regulates its activity, its cellular localization, and cell growth. Mol Cell Biol 19: 1301-1312, 1999.
    • (1999) Mol Cell Biol , vol.19 , pp. 1301-1312
    • Abe, M.K.1    Kuo, W.L.2    Hershenson, M.B.3    Rosner, M.R.4
  • 2
    • 0027306121 scopus 로고
    • The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activity by oncogenic ras in Xenopus oocyte extracts
    • Alessi DR, Smythe C, Keyse SM. The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activity by oncogenic ras in Xenopus oocyte extracts. Oncogene 8: 2015-2020, 1993.
    • (1993) Oncogene , vol.8 , pp. 2015-2020
    • Alessi, D.R.1    Smythe, C.2    Keyse, S.M.3
  • 4
    • 0142213140 scopus 로고    scopus 로고
    • Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-α in IEC-6 cells
    • Bhattacharya S, Ray RM, Viar MJ, Johnson LR. Polyamines are required for activation of c-Jun NH2-terminal kinase and apoptosis in response to TNF-α in IEC-6 cells. Am J Physiol Gastrointest Liver Physiol 285: G980-G991, 2003.
    • (2003) Am J Physiol Gastrointest Liver Physiol , vol.285
    • Bhattacharya, S.1    Ray, R.M.2    Viar, M.J.3    Johnson, L.R.4
  • 5
    • 1342322887 scopus 로고    scopus 로고
    • Prevention of TNF-α-induced apoptosis in polyamine-depleted IEC-6 cells is mediated through the activation of ERK1/2
    • Bhattacharya S, Ray RM, Johnson LR. Prevention of TNF-α-induced apoptosis in polyamine-depleted IEC-6 cells is mediated through the activation of ERK1/2. Am J Physiol Gastrointest Liver Physiol 286: G479-G490, 2004.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286
    • Bhattacharya, S.1    Ray, R.M.2    Johnson, L.R.3
  • 6
    • 23944497169 scopus 로고    scopus 로고
    • Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-κB activation but not GSK3β activity
    • Bhattacharya S, Ray RM, Johnson LR. Decreased apoptosis in polyamine depleted IEC-6 cells depends on Akt-mediated NF-κB activation but not GSK3β activity. Apoptosis 10: 759-776, 2005.
    • (2005) Apoptosis , vol.10 , pp. 759-776
    • Bhattacharya, S.1    Ray, R.M.2    Johnson, L.R.3
  • 7
    • 59749090405 scopus 로고    scopus 로고
    • Role of polyamines in p53-dependent apoptosis of intestinal epithelials
    • Bhattacharya S, Ray RM, Johnson LR. Role of polyamines in p53-dependent apoptosis of intestinal epithelials. Cell Signal 21: 509-522, 2009.
    • (2009) Cell Signal , vol.21 , pp. 509-522
    • Bhattacharya, S.1    Ray, R.M.2    Johnson, L.R.3
  • 9
    • 54049141728 scopus 로고    scopus 로고
    • Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer
    • Boutros T, Chevet E, Metrakos P. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: roles in cell growth, death, and cancer. Pharmacol Rev 60: 261-310, 2008.
    • (2008) Pharmacol Rev , vol.60 , pp. 261-310
    • Boutros, T.1    Chevet, E.2    Metrakos, P.3
  • 10
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: A gene family for control of MAP kinase function
    • Camps M, Nichols A, Arkinstall S. Dual specificity phosphatases: a gene family for control of MAP kinase function. FASEB J 14: 6-16, 2000.
    • (2000) FASEB J , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 11
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • Chen G, Goeddel DV. TNF-R1 signaling: a beautiful pathway. Science 296: 1634-1635, 2002.
    • (2002) Science , vol.296 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 12
    • 0141953270 scopus 로고    scopus 로고
    • A JNK-dependent pathway is required for TNF-α-induced apoptosis
    • Deng Y, Ren X, Yang L, Lin Y, Wu X. A JNK-dependent pathway is required for TNF-α-induced apoptosis. Cell 115: 61-70, 2003.
    • (2003) Cell , vol.115 , pp. 61-70
    • Deng, Y.1    Ren, X.2    Yang, L.3    Lin, Y.4    Wu, X.5
  • 13
    • 0028935974 scopus 로고
    • Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
    • Derijard B, Raingeaud J, Barrett T, Wu IH, Han J, Ulevitch RJ, Davis RJ. Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 5198: 682-685, 1995.
    • (1995) Science , vol.5198 , pp. 682-685
    • Derijard, B.1    Raingeaud, J.2    Barrett, T.3    Wu, I.H.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 14
    • 0037174934 scopus 로고    scopus 로고
    • JNK phosphorylation and activation of Bad couples the stress-activated signaling pathway to the cell death machinery
    • Donovan N, Becker EB, Konishi Y, Bonni A. JNK phosphorylation and activation of Bad couples the stress-activated signaling pathway to the cell death machinery. J Biol Chem 277: 40944-40949, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 40944-40949
    • Donovan, N.1    Becker, E.B.2    Konishi, Y.3    Bonni, A.4
  • 15
    • 3442886811 scopus 로고    scopus 로고
    • The pathophysiology of mitochondrial cell death
    • Green DR, Kroemer G. The pathophysiology of mitochondrial cell death. Science 305: 626-629, 2004.
    • (2004) Science , vol.305 , pp. 626-629
    • Green, D.R.1    Kroemer, G.2
  • 16
    • 2042538029 scopus 로고    scopus 로고
    • Structure and regulation of MAPK phosphatases
    • Farooq A, Zhou MM. Structure and regulation of MAPK phosphatases. Cell Signal 16: 769-779, 2004.
    • (2004) Cell Signal , vol.16 , pp. 769-779
    • Farooq, A.1    Zhou, M.M.2
  • 17
    • 0030794511 scopus 로고    scopus 로고
    • Conditional expression of mitogen-activated protein kinase (MAPK) phosphatase, MKP-1, preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells
    • Franklin CC, Kraft AS. Conditional expression of mitogen-activated protein kinase (MAPK) phosphatase, MKP-1, preferentially inhibits p38 MAPK and stress-activated protein kinase in U937 cells. J Biol Chem 272: 16917-16923, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 16917-16923
    • Franklin, C.C.1    Kraft, A.S.2
  • 18
    • 0032539919 scopus 로고    scopus 로고
    • Conditional expression of mitogenactivated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis
    • Franklin CC, Srikanth S, Kraft AS. Conditional expression of mitogenactivated protein kinase phosphatase-1, MKP-1, is cytoprotective against UV-induced apoptosis. Proc Natl Acad Sci USA 95: 3014-3019, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 3014-3019
    • Franklin, C.C.1    Srikanth, S.2    Kraft, A.S.3
  • 20
    • 0029905354 scopus 로고    scopus 로고
    • Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase
    • Groom LA, Sneddon AA, Alessi DR, Dowd S, Keyse SM. Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase. EMBO J 15: 3621-3632, 1996.
    • (1996) EMBO J , vol.15 , pp. 3621-3632
    • Groom, L.A.1    Sneddon, A.A.2    Alessi, D.R.3    Dowd, S.4    Keyse, S.M.5
  • 21
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signaling pathway
    • Gupta S, Campbell D, Derijard B, Davis RJ. Transcription factor ATF2 regulation by the JNK signaling pathway. Science 267: 389-393, 1995.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 22
    • 0348010361 scopus 로고    scopus 로고
    • The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis
    • Ham YM, Choi JS, Chun KH, Joo SH, Lee SK. The c-Jun N-terminal kinase 1 activity is differentially regulated by specific mechanisms during apoptosis. J Biol Chem 278: 50330-50337, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 50330-50337
    • Ham, Y.M.1    Choi, J.S.2    Chun, K.H.3    Joo, S.H.4    Lee, S.K.5
  • 24
    • 41549160315 scopus 로고    scopus 로고
    • Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival
    • Junttila MR, Li SP, Westermarck J. Phosphatase-mediated crosstalk between MAPK signaling pathways in the regulation of cell survival. FASEB J 22: 954-965, 2008.
    • (2008) FASEB J , vol.22 , pp. 954-965
    • Junttila, M.R.1    Li, S.P.2    Westermarck, J.3
  • 26
    • 0036009115 scopus 로고    scopus 로고
    • NF-κB at the crossroads of life and death
    • Karin M, Lin A. NF-κB at the crossroads of life and death. Nat Immunol 3: 221-227, 2002.
    • (2002) Nat Immunol , vol.3 , pp. 221-227
    • Karin, M.1    Lin, A.2
  • 27
    • 0034096201 scopus 로고    scopus 로고
    • Protein phosphatases and the regulation of mitogen-activated protein kinase signaling
    • Keyse SM. Protein phosphatases and the regulation of mitogen-activated protein kinase signaling. Curr Opin Cell Biol 12: 186-192, 2000.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 186-192
    • Keyse, S.M.1
  • 28
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse SM. Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27: 253-261, 2008.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 29
    • 0028924419 scopus 로고
    • Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-jun N-terminal kinase activity and AP-1 dependent gene activation
    • Liu Y, Gorospe M, Yang C, Holbrook NJ. Role of mitogen-activated protein kinase phosphatase during the cellular response to genotoxic stress. Inhibition of c-jun N-terminal kinase activity and AP-1 dependent gene activation. J Biol Chem 270: 8377-8380, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 8377-8380
    • Liu, Y.1    Gorospe, M.2    Yang, C.3    Holbrook, N.J.4
  • 31
    • 0344393408 scopus 로고    scopus 로고
    • Regulation of MAP kinase signaling modules by scaffold proteins in mammals
    • Morrison DK, Davis RJ. Regulation of MAP kinase signaling modules by scaffold proteins in mammals. Annu Rev Cell Dev Biol 19: 91-118, 2003.
    • (2003) Annu Rev Cell Dev Biol , vol.19 , pp. 91-118
    • Morrison, D.K.1    Davis, R.J.2
  • 32
    • 3242690631 scopus 로고    scopus 로고
    • Signaling crosstalk between NF-κB and JNK
    • Nakano H. Signaling crosstalk between NF-κB and JNK. Trends Immunol 25: 402-405, 2004.
    • (2004) Trends Immunol , vol.25 , pp. 402-405
    • Nakano, H.1
  • 33
    • 0037376788 scopus 로고    scopus 로고
    • Cell surface death receptor signaling in normal and cancer cells
    • Ozören N, El-Deiry WS. Cell surface death receptor signaling in normal and cancer cells. Semin Cancer Biol 13: 135-147, 2003.
    • (2003) Semin Cancer Biol , vol.13 , pp. 135-147
    • Ozören, N.1    El-Deiry, W.S.2
  • 35
    • 0018394382 scopus 로고
    • Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria
    • Quaroni A, Wands J, Trelstad RL, Isselbacher KJ. Epithelioid cell cultures from rat small intestine. Characterization by morphologic and immunologic criteria. J Cell Biol 80: 248-265, 1979.
    • (1979) J Cell Biol , vol.80 , pp. 248-265
    • Quaroni, A.1    Wands, J.2    Trelstad, R.L.3    Isselbacher, K.J.4
  • 36
    • 0028935270 scopus 로고
    • Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase by dual phosphorylation on tyrosine and threonine
    • Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ. Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase by dual phosphorylation on tyrosine and threonine. J Biol Chem 270: 7420-7426, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 7420-7426
    • Raingeaud, J.1    Gupta, S.2    Rogers, J.S.3    Dickens, M.4    Han, J.5    Ulevitch, R.J.6    Davis, R.J.7
  • 37
  • 38
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen GS, Dixit VM. Caspases: intracellular signaling by proteolysis. Cell 91: 443-461, 1997.
    • (1997) Cell , vol.91 , pp. 443-461
    • Salvesen, G.S.1    Dixit, V.M.2
  • 39
    • 0032576868 scopus 로고    scopus 로고
    • Cisplatin induces a persistent activation of JNK that is related to cell death
    • Sánchez-Perez I, Murguía JR, Perona R. Cisplatin induces a persistent activation of JNK that is related to cell death. Oncogene 16: 533-540, 1998.
    • (1998) Oncogene , vol.16 , pp. 533-540
    • Sánchez-Perez, I.1    Murguía, J.R.2    Perona, R.3
  • 41
    • 0035844140 scopus 로고    scopus 로고
    • Distinct binding determinants for ERK2/p38α and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1
    • Slack DN, Seternes OM, Gabrielsen M, Keyse SM. Distinct binding determinants for ERK2/p38α and JNK MAP kinases mediate catalytic activation and substrate selectivity of MAP kinase phosphatase-1. J Biol Chem 276: 16491-16500, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 16491-16500
    • Slack, D.N.1    Seternes, O.M.2    Gabrielsen, M.3    Keyse, S.M.4
  • 43
    • 0027358722 scopus 로고
    • MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
    • Sun H, Charles CH, Lau LF, Tonks NK. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 75: 487-493, 1993.
    • (1993) Cell , vol.75 , pp. 487-493
    • Sun, H.1    Charles, C.H.2    Lau, L.F.3    Tonks, N.K.4
  • 44
    • 0242656497 scopus 로고    scopus 로고
    • Death receptor-induced cell killing
    • Thorburn A. Death receptor-induced cell killing. Cell Signal 16: 139-144, 2004.
    • (2004) Cell Signal , vol.16 , pp. 139-144
    • Thorburn, A.1
  • 45
    • 2342562556 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases in apoptosis regulation
    • Wada T, Penninger JM. Mitogen-activated protein kinases in apoptosis regulation. Oncogene 23: 2838-2849, 2004.
    • (2004) Oncogene , vol.23 , pp. 2838-2849
    • Wada, T.1    Penninger, J.M.2
  • 47
    • 0032508714 scopus 로고    scopus 로고
    • A mammalian scaffold complex that selectively mediates MAP kinase activation
    • Whitmarsh AJ, Cavangh J, Tournier C, Yasuda J, Davis RJ. A mammalian scaffold complex that selectively mediates MAP kinase activation. Science 281: 1671-1674, 1998.
    • (1998) Science , vol.281 , pp. 1671-1674
    • Whitmarsh, A.J.1    Cavangh, J.2    Tournier, C.3    Yasuda, J.4    Davis, R.J.5
  • 48
    • 18144384775 scopus 로고    scopus 로고
    • Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling
    • Wu JJ, Bennett AM. Essential role for mitogen-activated protein (MAP) kinase phosphatase-1 in stress-responsive MAP kinase and cell survival signaling. J Biol Chem 280: 16461-16466, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 16461-16466
    • Wu, J.J.1    Bennett, A.M.2
  • 49
    • 0037439170 scopus 로고    scopus 로고
    • POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis
    • Xu Z, Kukekov NV, Greene LA. POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. EMBO J 22: 252-261, 2003.
    • (2003) EMBO J , vol.22 , pp. 252-261
    • Xu, Z.1    Kukekov, N.V.2    Greene, L.A.3
  • 50
    • 0027323844 scopus 로고
    • Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr phosphatase
    • Zheng CF, Guan KL. Dephosphorylation and inactivation of the mitogen-activated protein kinase by a mitogen-induced Thr/Tyr phosphatase. J Biol Chem 268: 16116-16119, 1993.
    • (1993) J Biol Chem , vol.268 , pp. 16116-16119
    • Zheng, C.F.1    Guan, K.L.2
  • 51
    • 0029055761 scopus 로고
    • Components of a new human protein kinase signal transduction pathway
    • Zhou G, Bao ZQ, Dixon JE. Components of a new human protein kinase signal transduction pathway. J Biol Chem 270: 12665-12669, 1995.
    • (1995) J Biol Chem , vol.270 , pp. 12665-12669
    • Zhou, G.1    Bao, Z.Q.2    Dixon, J.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.