Signaling crosstalk between NF-κB and JNK

Trends in Immunology

Volumn 25, Issue 8, 2004, Pages 402-405

  Nakano, Hiroyasu ^a,b  

^a JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

APOPTOSIS; DOWN REGULATION; FIBROBLAST; MOLECULE; NONHUMAN; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION; X CHROMOSOME;

EID: 3242690631     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2004.05.007     Document Type: Short Survey

References (25)

1. Ghosh S., Karin M. Missing pieces in the NF-κB puzzle. Cell. 109:(Suppl):2002;S81-S96
2. Barkett M., Gilmore T.D. Control of apoptosis by Rel/NF-κB transcription factors. Oncogene. 18:1999;6910-6924
3. Karin M., Lin A. NF-κB at the crossroads of life and death. Nat. Immunol. 3:2002;221-227
4. Davis R.J. Signal transduction by the JNK group of MAP kinases. Cell. 103:2000;239-252
5. Lin A. Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays. 25:2003;17-24
6. Chen Y.R., et al. The role of c-Jun N-terminal kinase (JNK) in apoptosis induced by ultraviolet C and γ radiation. Duration of JNK activation may determine cell death and proliferation. J. Biol. Chem. 271:1996;31929-31936
7. Tournier C., et al. Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway. Science. 288:2000;870-874
8. Reuther-Madrid J.Y., et al. The p65/RelA subunit of NF-κB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor. Mol. Cell. Biol. 22:2002;8175-8183
9. Lamb J.A., et al. JunD mediates survival signaling by the JNK signal transduction pathway. Mol. Cell. 11:2003;1479-1489
10. Yu C., et al. JNK suppresses apoptosis via phosphorylation of the proapoptotic Bcl-2 family protein BAD. Mol. Cell. 13:2004;329-340
11. De Smaele E., et al. Induction of gadd45β by NF-κB downregulates pro-apoptotic JNK signalling. Nature. 414:2001;308-313
12. Tang G., et al. Inhibition of JNK activation through NF-κB target genes. Nature. 414:2001;313-317
13. Guo Y.L., et al. Correlation between sustained c-Jun N-terminal protein kinase activation and apoptosis induced by tumor necrosis factor-α in rat mesangial cells. J. Biol. Chem. 273:1998;4027-4034
14. Tobiume K., et al. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis. EMBO Rep. 2:2001;222-228
15. Papa S., et al. Gadd45β mediates the NF-κB suppression of JNK signalling by targeting MKK7/JNKK2. Nat. Cell Biol. 6:2004;146-153
16. Sakon S., et al. NF-κB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death. EMBO J. 22:2003;3898-3909
17. Chen F., et al. Inhibitor of nuclear factor κB kinase deficiency enhances oxidative stress and prolongs c-Jun NH2-terminal kinase activation induced by arsenic. Cancer Res. 63:2003;7689-7693
18. Maeda S., et al. IKKβ is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFα Immunity. 19:2003;725-737
19. Vives E., et al. A truncated HIV-1 Tat protein basic domain rapidly translocates through the plasma membrane and accumulates in the cell nucleus. J. Biol. Chem. 272:1997;16010-16017
20. Amanullah A., et al. Cell signalling: cell survival and a Gadd45-factor deficiency. Nature. 424:2003;741-742
21. Tada K., et al. Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-κB activation and protection from cell death. J. Biol. Chem. 276:2001;36530-36534
22. Sasazuki, T. et al. Genome wide analysis of TNF-inducible genes reveals that antioxidant enzymes are induced by TNF and responsible for elimination of ROS. Mol. Immunol. (in press).
23. Takekawa M., Saito H. A family of stress-inducible GADD45-like proteins mediate activation of the stress-responsive MTK1/MEKK4 MAPKKK. Cell. 95:1998;521-530
24. Deng Y., et al. A JNK-dependent pathway is required for TNFα-induced apoptosis. Cell. 115:2003;61-70
25. Tak P.P., Firestein G.S. NF-κB: a key role in inflammatory diseases. J. Clin. Invest. 107:2001;7-11