Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowth

Journal of Cell Biology

Volumn 192, Issue 6, 2011, Pages 993-1004

  Greer, Yoshimi Endo ^a   Rubin, Jeffrey S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; DISHEVELLED 2; DISHEVELLED 3; GAMMA TUBULIN; PERICENTRIN; PHOSPHOPROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; WNT3A PROTEIN;

ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; CENTROSOME; FEMALE; HELA CELL; HUMAN; HUMAN CELL; NERVE FIBER GROWTH; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; RAT; WILD TYPE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CASEIN KINASE IDELTA; CASEIN KINASE IEPSILON; CELL LINE; CENTROSOME; DNA MUTATIONAL ANALYSIS; HUMANS; ISOENZYMES; MICE; NEURITES; PHOSPHOPROTEINS; RECOMBINANT FUSION PROTEINS; RNA, SMALL INTERFERING; WNT PROTEINS;

EID: 79955506828     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.201011111     Document Type: Article

References (57)

1. Babu, P., J.D. Bryan, H.R. Panek, S.L. Jordan, B.M. Forbrich, S.C. Kelley, R.T. Colvin, L.C. Robinson. 2002. Plasma membrane localization of the Yck2p yeast casein kinase 1 isoform requires the C-terminal extension and secretory pathway function. J. Cell Sci. 115:4957-4968.
2. Bahmanyar, S., D.D. Kaplan, J.G. Deluca, T.H. Giddings Jr, E.T. O'Toole, M. Winey, E.D. Salmon, P.J. Casey, W.J. Nelson, A.I. Barth. 2008. beta-Catenin is a Nek2 substrate involved in centrosome separation. Genes Dev. 22:91-105.
3. Behrend, L., D.M. Milne, M. Stöter, W. Deppert, L.E. Campbell, D.W. Meek, U. Knippschild. 2000. IC261, a specific inhibitor of the protein kinases casein kinase 1-delta and -epsilon, triggers the mitotic checkpoint and induces p53-dependent postmitotic effects. Oncogene. 19:5303-5313.
4. Bryja, V., G. Schulte, E. Arenas. 2007a. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cell. Signal. 19:610-616.
5. Bryja, V., G. Schulte, N. Rawal, A. Grahn, E. Arenas. 2007b. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. J. Cell Sci. 120:586-595.
6. Bryja, V., A. Schambony, L. Cajánek, I. Dominguez, E. Arenas, G. Schulte. 2008. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. EMBO Rep. 9:1244-1250.
7. Ciani, L., P.C. Salinas. 2005. WNTs in the vertebrate nervous system: from patterning to neuronal connectivity. Nat. Rev. Neurosci. 6:351-362.
8. Ciani, L., O. Krylova, M.J. Smalley, T.C. Dale, P.C. Salinas. 2004. A divergent canonical WNT-signaling pathway regulates microtubule dynamics: dishevelled signals locally to stabilize microtubules. J. Cell Biol. 164:243-253.
9. Cong, F., L. Schweizer, H. Varmus. 2004. Casein kinase Iepsilon modulates the signaling specificities of dishevelled. Mol. Cell. Biol. 24:2000-2011.
10. Dahlberg, C.L., E.Z. Nguyen, D. Goodlett, D. Kimelman. 2009. Interactions between Casein kinase Iepsilon (CKIepsilon) and two substrates from disparate signaling pathways reveal mechanisms for substrate-kinase specificity. PLoS ONE. 4:e4766.
11. de Anda, F.C., G. Pollarolo, J.S. Da Silva, P.G. Camoletto, F. Feiguin, C.G. Dotti. 2005. Centrosome localization determines neuronal polarity. Nature. 436:704-708.
12. Endo, Y., J.S. Rubin. 2007. Wnt signaling and neurite outgrowth: insights and questions. Cancer Sci. 98:1311-1317.
13. Endo, Y., E. Beauchamp, D. Woods, W.G. Taylor, J.A. Toretsky, A. Uren, J.S. Rubin. 2008. Wnt-3a and Dickkopf-1 stimulate neurite outgrowth in Ewing tumor cells via a Frizzled3- and c-Jun N-terminal kinase-dependent mechanism. Mol. Cell. Biol. 28:2368-2379.
14. Etchegaray, J.P., K.K. Machida, E. Noton, C.M. Constance, R. Dallmann, M.N. Di Napoli, J.P. DeBruyne, C.M. Lambert, E.A. Yu, S.M. Reppert, D.R. Weaver. 2009. Casein kinase 1 delta regulates the pace of the mammalian circadian clock. Mol. Cell. Biol. 29:3853-3866.
15. Gao, C., Y.G. Chen. 2010. Dishevelled: The hub of Wnt signaling. Cell. Signal. 22:717-727.
16. González-Sancho, J.M., K.R. Brennan, L.A. Castelo-Soccio, A.M. Brown. 2004. Wnt proteins induce dishevelled phosphorylation via an LRP5/6- independent mechanism, irrespective of their ability to stabilize beta-catenin. Mol. Cell. Biol. 24:4757-4768.
17. Graves, P.R., P.J. Roach. 1995. Role of COOH-terminal phosphorylation in the regulation of casein kinase I delta. J. Biol. Chem. 270:21689-21694.
18. Gross, S.D., R.A. Anderson. 1998. Casein kinase I: spatial organization and positioning of a multifunctional protein kinase family. Cell. Signal. 10:699-711.
19. Gross, S.D., C. Simerly, G. Schatten, R.A. Anderson. 1997. A casein kinase I isoform is required for proper cell cycle progression in the fertilized mouse oocyte. J. Cell Sci. 110:3083-3090.
20. Hadjihannas, M.V., M. Brückner, J. Behrens. 2010. Conductin/axin2 and Wnt signalling regulates centrosome cohesion. EMBO Rep. 11:317-324.
21. Higginbotham, H.R., J.G. Gleeson. 2007. The centrosome in neuronal development. Trends Neurosci. 30:276-283.
22. Kikuchi, K., Y. Niikura, K. Kitagawa, A. Kikuchi. 2010. Dishevelled, a Wnt signalling component, is involved in mitotic progression in cooperation with Plk1. EMBO J. 29:3470-3483.
23. Klaus, A., W. Birchmeier. 2008. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer. 8:387-398.
24. Klein, T.J., A. Jenny, A. Djiane, M. Mlodzik. 2006. CKIepsilon/discs overgrown promotes both Wnt-Fz/beta-catenin and Fz/PCP signaling in Drosophila. Curr. Biol. 16:1337-1343.
25. Knippschild, U., A. Gocht, S. Wolff, N. Huber, J. Löhler, M. Stöter. 2005. The casein kinase 1 family: participation in multiple cellular processes in eukaryotes. Cell. Signal. 17:675-689.
26. Krylova, O., M.J. Messenger, P.C. Salinas. 2000. Dishevelled-1 regulates microtubule stability: a new function mediated by glycogen synthase kinase-3beta. J. Cell Biol. 151:83-94.
27. Lee, H., R. Chen, Y. Lee, S. Yoo, C. Lee. 2009. Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock. Proc. Natl. Acad. Sci. USA. 106:21359-21364.
28. Liu, Y., J. Shi, C.C. Lu, Z.B. Wang, A.I. Lyuksyutova, X.J. Song, Y. Zou. 2005. Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract. Nat. Neurosci. 8:1151-1159.
29. Lowrey, P.L., K. Shimomura, M.P. Antoch, S. Yamazaki, P.D. Zemenides, M.R. Ralph, M. Menaker, J.S. Takahashi. 2000. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science. 288:483-492.
30. Lu, W., V. Yamamoto, B. Ortega, D. Baltimore. 2004. Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth. Cell. 119:97-108.
31. Lyuksyutova, A.I., C.C. Lu, N. Milanesio, L.A. King, N. Guo, Y. Wang, J. Nathans, M. Tessier-Lavigne, Y. Zou. 2003. Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science. 302:1984-1988.
32. Malaterre, J., R.G. Ramsay, T. Mantamadiotis. 2007. Wnt-Frizzled signalling and the many paths to neural development and adult brain homeostasis. Front. Biosci. 12:492-506.
33. Mashhoon, N., A.J. DeMaggio, V. Tereshko, S.C. Bergmeier, M. Egli, M.F. Hoekstra, J. Kuret. 2000. Crystal structure of a conformation-selective casein kinase-1 inhibitor. J. Biol. Chem. 275:20052-20060.
34. Matsumoto, Y., J.L. Maller. 2004. A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry. Science. 306:885-888.
35. McKay, R.M., J.M. Peters, J.M. Graff. 2001. The casein kinase I family in Wnt signaling. Dev. Biol. 235:388-396.
36. Meng, Q.J., E.S. Maywood, D.A. Bechtold, W.Q. Lu, J. Li, J.E. Gibbs, S.M. Dupré, J.E. Chesham, F. Rajamohan, J. Knafels, et al. 2010. Entrainment of disrupted circadian behavior through inhibition of casein kinase 1 (CK1) enzymes. Proc. Natl. Acad. Sci. USA. 107:15240-15245.
37. Milne, D.M., P. Looby, D.W. Meek. 2001. Catalytic activity of protein kinase CK1 delta (casein kinase 1delta) is essential for its normal subcellular localization. Exp. Cell Res. 263:43-54.
38. Park, T.J., B.J. Mitchell, P.B. Abitua, C. Kintner, J.B. Wallingford. 2008. Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells. Nat. Genet. 40:871-879.
39. Pascreau, G., F. Eckerdt, M.E. Churchill, J.L. Maller. 2010. Discovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding. Proc. Natl. Acad. Sci. USA. 107:2932-2937.
40. Peters, J.M., R.M. McKay, J.P. McKay, J.M. Graff. 1999. Casein kinase I transduces Wnt signals. Nature. 401:345-350.
41. Robinson, L.C., C. Bradley, J.D. Bryan, A. Jerome, Y. Kweon, H.R. Panek. 1999. The Yck2 yeast casein kinase 1 isoform shows cell cycle-specific localization to sites of polarized growth and is required for proper septin organization. Mol. Biol. Cell. 10:1077-1092.
42. Rosso, S.B., D. Sussman, A. Wynshaw-Boris, P.C. Salinas. 2005. Wnt signaling through Dishevelled, Rac and JNK regulates dendritic development. Nat. Neurosci. 8:34-42.
43. Sakanaka, C., P. Leong, L. Xu, S.D. Harrison, L.T. Williams. 1999. Casein kinase iepsilon in the wnt pathway: regulation of beta-catenin function. Proc. Natl. Acad. Sci. USA. 96:12548-12552.
44. Salinas, P.C., Y. Zou. 2008. Wnt signaling in neural circuit assembly. Annu. Rev. Neurosci. 31:339-358.
45. Sánchez-Camacho, C., P. Bovolenta. 2009. Emerging mechanisms in morphogen-mediated axon guidance. Bioessays. 31:1013-1025.
46. Schmidt, P.H., D.T. Dransfield, J.O. Claudio, R.G. Hawley, K.W. Trotter, S.L. Milgram, J.R. Goldenring. 1999. AKAP350, a multiply spliced protein kinase A-anchoring protein associated with centrosomes. J. Biol. Chem. 274:3055-3066.
47. Schulte, G., V. Bryja, N. Rawal, G. Castelo-Branco, K.M. Sousa, E. Arenas. 2005. Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. J. Neurochem. 92:1550-1553.
48. Sillibourne, J.E., D.M. Milne, M. Takahashi, Y. Ono, D.W. Meek. 2002. Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450. J. Mol. Biol. 322:785-797.
49. Stöter, M., A.M. Bamberger, B. Aslan, M. Kurth, D. Speidel, T. Löning, H.G. Frank, P. Kaufmann, J. Löhler, D. Henne-Bruns, et al. 2005. Inhibition of casein kinase I delta alters mitotic spindle formation and induces apoptosis in trophoblast cells. Oncogene. 24:7964-7975.
50. Strutt, H., M.A. Price, D. Strutt. 2006. Planar polarity is positively regulated by casein kinase Iepsilon in Drosophila. Curr. Biol. 16:1329-1336.
51. Takahashi, M., H. Shibata, M. Shimakawa, M. Miyamoto, H. Mukai, Y. Ono. 1999. Characterization of a novel giant scaffolding protein, CG-NAP, that anchors multiple signaling enzymes to centrosome and the golgi apparatus. J. Biol. Chem. 274:17267-17274.
52. Wallingford, J.B., R. Habas. 2005. The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarity. Development. 132:4421-4436.
53. Wang, Z., T. Wu, L. Shi, L. Zhang, W. Zheng, J.Y. Qu, R. Niu, R.Z. Qi. 2010. Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex. J. Biol. Chem. 285:22658-22665.
54. Wolf, A.M., A.I. Lyuksyutova, A.G. Fenstermaker, B. Shafer, C.G. Lo, Y. Zou. 2008. Phosphatidylinositol-3-kinase-atypical protein kinase C signaling is required for Wnt attraction and anterior-posterior axon guidance. J. Neurosci. 28:3456-3467.
55. Yoshikawa, S., R.D. McKinnon, M. Kokel, J.B. Thomas. 2003. Wnt-mediated axon guidance via the Drosophila Derailed receptor. Nature. 422:583-588.
56. Zhang, X., J. Zhu, G.Y. Yang, Q.J. Wang, L. Qian, Y.M. Chen, F. Chen, Y. Tao, H.S. Hu, T. Wang, Z.G. Luo. 2007. Dishevelled promotes axon differentiation by regulating atypical protein kinase C. Nat. Cell Biol. 9:743-754.
57. Zinchuk, V., O. Zinchuk, T. Okada. 2007. Quantitative colocalization analysis of multicolor confocal immunofluorescence microscopy images: pushing pixels to explore biological phenomena. Acta Histochem. Cytochem. 40:101-111.