Aromatic ring functionalization of benzolactam derivatives: New potent dopamine D3 receptor ligands

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 9, 2011, Pages 2670-2674

  Ortega, Raquel ^a   Hübner, Harald ^b   Gmeiner, Peter ^b   Masaguer, Christian F ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

Antipsychotics; Arylpiperazines; Benzolactams; Dopamine receptors; Structure activity relationship

Indexed keywords

DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR STIMULATING AGENT; LACTAM DERIVATIVE; PALLADIUM; QUINPIROLE; UNCLASSIFIED DRUG; USC A 401; USC B 401; USC G 401; USC H 401; USC I 401; USC J 401; USC K 401; USC L 401; USC M 401; USC N 401; USC O 401; USC P 401;

ANIMAL CELL; BINDING AFFINITY; CATALYSIS; CONFERENCE PAPER; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG TARGETING; NONHUMAN; SUBSTITUTION REACTION;

BENZODIAZEPINONES; CATALYSIS; CELLS, CULTURED; HUMANS; LACTAMS; LIGANDS; MOLECULAR STRUCTURE; PALLADIUM; PROTEIN BINDING; RECEPTORS, DOPAMINE D3;

EID: 79955478586     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.12.083     Document Type: Conference Paper

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