Linking the family of D2 receptors to neuronal circuits in human brain: Insights into schizophrenia

Neuropsychopharmacology

Volumn 16, Issue 6, 1997, Pages 375-384

  Joyce, Jeffrey N ^a   Meador Woodruff, James H ^b  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Basal ganglia; Cortex; D2 dopamine receptors; D3 dopamine receptors; D4 dopamine receptors; Hippocampus; Messenger RNA

Indexed keywords

CLOZAPINE; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; HALOPERIDOL; NEUROLEPTIC AGENT; SULPIRIDE;

BASAL GANGLION; DOPAMINERGIC SYSTEM; DRUG RECEPTOR BINDING; EXTRAPYRAMIDAL SYMPTOM; HIPPOCAMPUS; HUMAN; LIMBIC CORTEX; NIGRONEOSTRIATAL SYSTEM; NONHUMAN; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA; TEMPORAL LOBE; BRAIN; NERVE CELL NETWORK; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

BRAIN; HUMANS; NERVE NET; RECEPTORS, DOPAMINE D2; SCHIZOPHRENIA;

EID: 0030610748     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0893-133X(96)00276-X     Document Type: Review

References (79)

1. Akbarian S, Vinuela A, KiM JJ, Potkin SG, Bunney WE Jr, Jones EG (1993): Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development. Arch Gen Psychiat 50:178-187
2. Alexander GE, Crutcher MD (1990): Functional architecture of basal ganglia circuits: Neural substrates of parallel processing. TINS 13:266-271
3. Amalric M, Koob GF (1993): Functionally selective neurochemical afferents and efferents of the mesocorticolimbic and nigrostriatal dopamine system. Prog Brain Res 99:209-226
4. Amaral DG (1993): Emerging principles of intrinsic hippocampal organization. Curr Opin Neurobiol 3:225-229
5. Arnold SE, Hyman BT, Van Hoesen GW, Damasio AR (1991): Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia. Arch Gen Psychiatr 48:625-632
6. 2 receptors. Nature 377:424-428
7. Berger B, Gaspar P, Verney C (1991): Dopaminergic innervation of the cerebral cortex: Unexpected differences between rodents and primates. TINS 14:21-27
8. Berman KF, Illowsky BP, Weinberger DR (1988): Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. IV. Further evidence for regional and behavioral specificity. Arch Gen Psychiatr 45:616-622
9. 3 receptor mRNA levels in rat brain following antipsychotic treatment. Psychopharmacology (Berl) 106(4):479-483
10. Clow A, Theodorou AE, Jenner P, Marsden CD (1980): A comparison of striatal and mesolimbic dopamine function in the rat during 6-month trifluoperazine administration. Psychopharmacology 69:227-233
11. Damask SP, Bovenkerk KA, de la Pena G, Hoversten KM, Peters DB, Valentine AM, Meador-Woodruff JH (1996): Differential effects of clozapine and haloperidol on dopamine receptor mRNA expression in rat striatum and cortex. Mol Brain Res 41:241-249
12. Davis KL, Kahn RS, Ko G, Davidson M (1991): Dopamine in schizophrenia: A review and reconceptualization. Am J Psychiatr 148:1474-1486
13. Deutch AY, Lee MC, Iadorola MJ (1992): Regionally specific effects of atypical antipsychotic drugs on striatal Fos expression: the nucleus accumbens shell as a locus of antipsychotic action. Mol Cell Neurosci 3:332-341
14. Falkai P, Bogerts B, Rozumak M (1988): Limbic pathology in schizophrenia: the entorhinal region - a morphometric study. Biol Psychiatr 24:515-521
15. 11C]raclopride. Arch Gen Psychiatr 47:213-219
16. 2 dopamine receptor subtype mRNA levels in the brain. FEBS Lett 339:63-66
17. Gibb WRG (1992): Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease. Brain Res 581:283-291
18. 2 receptor expression in hippocampus and parahippocampal cortices of human, rat and cat in comparison with tyrosine hydroxylase immunoreactive fibers. Hippocampus 4:1-20
19. 2 receptors are organized in bands in normal human temporal cortex. Neuroscience 74:435-451
20. 2 receptor in the temporal in schizophrenics: A postmortem study. Arch Gen Psychiatr
21. Graybiel AM (1995): The basal ganglia. TINS 18:60-62
22. Gur RE, Jaggi JL, Shtasel DL, Ragland JD, Gur RC (1994): Cerebral blood flow in schizophrenia: Effects of memory processing on regional activation. Biol Psychiatr 35:3-15
23. 3 receptors and use of antipsychotics in schizophrenic patients: A postmortem study. Arch Gen Psychiatr
24. Haber SN, Groenewegen HJ (1989): Interrelationship of the distribution of neuropeptides and tyrosine hydroxylase immunoreactivity in the human substantia nigra. J Comp Neurol 290:53-68
25. 2 antagonists as antipsychotic agents: Pharmacological, chemical, structural, and theoretical considerations. Acta Pharmacol 24:289-328
26. Jakob H, Beckmann H (1986): Prenatal developmental disturbances in the limbic allocortex in schizophrenics. J Neural Transm 65:303-326
27. 10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix. Neuroscience 23: 223-242
28. Joyce JN (1993): The dopamine hypothesis of schizophrenia: Limbic interactions with serotonin and norepinephrine. Psychopharmacology 112:516-534
29. Joyce JN, Sapp DW, Marshall JF (1986): Human striatal dopamine receptors are organized in compartments. Proc Natl Acad Sci U S A 83:8002-8006
30. 2 receptors in human striatum: receptor autoradiographic studies in Huntington's disease and schizophrenia. Synapse 2:546-557
31. Krimer LS, Herman MM, Saunders RC, Boyd JC, Kleinman JE, Hyde TM, Weinberger DR (1995): Qualitative and quantitative analysis of the entorhinal cortex cytoarchitectural organization in schizophrenia. Soc Neurosci Abstr 21:239
32. 2-family receptor distribution in human postmortem tissue: An autoradiographic study. Neuroreport 6:2505-2512
33. 2 receptor modulation in rat striatum and nucleus accumbens after chronic haloperidol treatment. Brain Res 575:47-56
34. 3 receptor expression suggests the involvement of an anterograde factor from dopamine neurons. Proc Natl Acad Sci U S A 92:1719-1723
35. Lidow MS, Goldman-Rakic PS, Rakic P (1991): Synchronized overproduction of neurotransmitter receptors in diverse regions of the primate cerebral cortex. Proc Natl Acad Sci U S A 88:10218-10221
36. Lynd-Balta E, Haber SN (1994a): The organization of midbrain projections to the ventral striatum in the primate. Neuroscience 59:609-623
37. Lynd-Balta E, Haber SN (1994b): The organization of midbrain projections to the striatum in the primate: sensorimotor-related striatum versus ventral striatum. Neuroscience 59:625-640
38. 76Br]-bromospiperone in untreated schizophrenic patients. Am J Psychiatr 147:44-50
39. Meador-Woodruff JH (1995): Neuroanatomy of dopamine receptor gene expression: Potential substrates for neuropsychiatric illness. Clin Neuropharmacol 18(suppl 1): S14-S24
40. Meador-Woodruff JH, Grandy DK, Van Tol HHM, Damask SP, Little O, Civelli KY, Watson SJ (1994a): Dopamine receptor gene expression in the human medial temporal lobe. Neuropsychopharmacology 10:239-248
41. Meador-Woodruff JH, Damask SP, Watson SJ (1994b): Differential expression of autoreceptors in the ascending dopamine systems of the human brain. Proc Natl Acad Sci U S A 91:8297-8301
42. Meador-Woodruff JH, Damask SP, Wang J, Haroutunian V, Davis KL, Watson SJ (1996): Dopamine receptor mRNA expression in human striatum and neocortex. Neuropsychopharmacology 15:17-30
43. Merchant KM, Dobie DJ, Dorsa DM (1992): Expression of the proneurotensin gene in the rat brain and its regulation by antipsychotic drugs. Ann NY Acad Sci 668:54-69
44. 2 receptors in chronic schizophrenics. Biol Psychiatr 21:1407-1414
45. Mogenson GJ, Yang CR, Yim CY (1988): Influence of dopamine on limbic inputs to the nucleus accumbens. Ann NY Acad Sci 537:86-100
46. Moghaddam B, Bunney BS (1990): Acute effect of typical and atypical antipsychotic drugs on the release of dopamine from prefrontal cortex, nucleus accumbens, and striatum of the rat: An in vivo microdialysis study. J Neurochem 54:1755-1760
47. 4 receptors in GABAergic neurons of the primate brain. Nature 381:245-248
48. 2 receptors to mesostriatal regions of human forebrain. Proc Natl Acad Sci U S A 91:11271-11275
49. 4 dopamine receptors in postmortem striatum from patients with schizophrenia. J Neurosci 15:2186-2191
50. Murugaiah K, Theodorou A, Mann S, Clow A, Jenner P, Marsden CD (1985): Chronic continuous administration of neuroleptic drugs alters cerebral dopamine receptors and increases spontaneous dopaminergic action in striatum. Nature 296:570-573
51. Nguyen TV, Kasofsky B, Birnbaum R, Cohen B, Hyman SE (1992): Differential expression of c-fos and Zif 268 in rat striatum following haloperidol, clozapine, and amphetamine. Proc Natl Acad Sci U S A 89:4270-4274
52. 11C]N-methylspiperone. Psychiatr Res 61:67-83
53. Owen F, Cross AJ, Crow TJ, Londgen A, Poulter M, Riley GJ (1978): Increased dopamine-receptor sensitivity in schizophrenia. Lancet 2:223-225
54. Pearlson GD, Petty RG, Ross CA, Tien AY (1996): Schizophrenia: A disease of heteromodal association cortex. Neuropsychopharmacology 14:1-18
55. Prosser ES, Pruthi R, Csernansky JG (1989): Differences in the time course of dopaminergic supersensitivity following chronic administration of haloperidol, molindone, or sulpiride. Psychopharmacology 99:109-116
56. Reinoso BS, Undie AS, Levit P (1996): Dopamine receptors mediate differential morphological effects on cerebral cortical neurons in vitro. J Neurosci Res 43:439-453
57. 4 receptors increased in schizophrenia? J Neurochem 63:1576-1577
58. Robertson GS, Fibiger HC (1992): Neuroleptics increase c-fos expression in the forebrain: Contrasting effects of haloperidol and clozapine. Neuroscience 46:315-328
59. Rosene DL, Van Hoesen GW (1987): The hippocampal formation of the primate brain. In Jones EG, Peters A (eds), Cerebral Cortex, vol 6, New York, Plenum Publishing, pp 361-370
60. Rubin P, Holm S, Friberg L, Videbech P, Andersen HS, Bendsen B, Stromso N, Larsen JK, Lassen NA, and Hemmingsen R (1991): Altered modulation of prefrontal and subcortical brain activity in new diagnosed schizophrenia and schizophreniform disorder. Arch Gen Psychiatry 48:987-995
61. Rupniak NMJ, Hall MD, Kelly E, Fleminger S, Kilpatric G, Jenner P, Marsden CD (1985): Mesolimbic dopamine function is not altered during continuous chronic treatment of rats with typical or atypical neuroleptic drugs. J Neural Transm 62:249-266
62. 2 receptors varies along the rostrocaudal axis of the hippocampal complex in Alzheimer's disease. J Comp Neurol 348:94-110
63. 4 receptors by 2-fold in rats. Eur J Pharmacol 289:67-72
64. 3 receptor: Basic and clinical aspects. Clin Neuropharmacol 16:295-314
65. 2 dopamine receptors in schizophrenia, Alzheimer's, Parkinson's and Huntington's disease. Neuropsychopharmacology 1:5-15
66. 4 receptors elevated in schizophrenia. Nature 1993:365: 441-445
67. Shapiro RM (1993): Regional neuropathology in schizophrenia: Where are we? Where are we going? Schizophrenia Res 10:187-239
68. 3) as a target for neuroleptics. Nature 347:146-151
69. 3H]-raclopride binding in postmortem caudate nucleus of subjects with schizophrenia or major depression. Brain Res 681:109-116
70. Swarzenski BC, Tang L, Oh YJ, O'Malley KL, Todd RD (1994): Morphogenic potentials of D2, D3, and D4 dopamine receptors revealed in transfected neuronal cell lines. Proc Nat Acad Sci U S A 91:649-653
71. Szabo J (1980): Organization of the ascending striatal afferents in monkeys. J Comp Neurol 189:307-321
72. Tamminga CA, Burrows GH, Chase TN, Alphs LD, Thaker GK (1988): Dopamine neuronal tracts in schizophrenia: Their pharmacology and in vivo glucose metabolism. Ann NY Acad Sci U S A 537:443-450
73. Tanaka C, Ishikawa M, Shinoda S (1982): Histochemical mapping of catecholaminergic neurons and their ascending fiber pathways in the rhesus monkey brain. Brain Res Bull 9:255-270
74. 4 receptor with high affinity for the antipsychotic clozapine. Nature 350:610-614
75. Waters CM Peck R, Rossor M, Reynolds GP, Hunt SP (1988): Immunocytochemical studies on the basal ganglia and substantia nigra in Parkinson's disease and Huntington's Chorea. Neurosci 25:419-438
76. Weinberger DR, Berman KF, Illowsky BP (1988): Physiological dysfunction of dorsolateral prefrontal cortex in schizophrenia. III. A new cohort and evidence for a monoaminergic mechanism. Arch Gen Psychiatr 45: 609-615
77. Weinberger DR, Berman KF, Suddath R, Torrey EF (1992): Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. Am J Psychiatr 149:890-897
78. 2 dopamine receptors in drug-naive schizophrenics. Science 234:1558-1563
79. 2 receptors: behavioral correlates. Neurosci Lett 161:223-236