6-Aryl-8H-indeno[1,2-d]thiazol-2-ylamines: A1 adenosine receptor agonist allosteric enhancers having improved potency

Journal of Medicinal Chemistry

Volumn 48, Issue 16, 2005, Pages 5131-5139

  Chordia, Mahendra D ^a   Zigler, Molly ^a   Murphree, Lauren J ^b   Figler, Heidi ^a   Macdonald, Timothy L ^a   Olsson, Ray A ^c   Linden, Joel ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 4,5 DIMETHYL 3 (3 TRIFLUOROMETHYLBENZOYL)THIOPHENE; 2 AMINOTHIAZOLE DERIVATIVE; 5 BROMOINDAN 1 ONE; 6 (3,4 DIMETHOXYPHENYL) 8H INDENO[1,2 D]THIAZOL 2 YLAMINE HYDROIODIDE; 6 (4 METHOXYPHENYL) 8H INDENO[1,2 D]THIAZOL 2 YLAMINE HYDROIODIDE; 6 (4 N,N DIMETHYLAMINOPHENYL) 8H INDENO[1,2 D]THIAZOL 2 YLAMINE; 6 (4 PHENOXYPHENYL) 8H INDENO[1,2 D]THIAZOL 2 YLAMINE HYDROIODIDE; 6 (NAPHTH 1 YL) 8H INDENO[1,2 D]THIAZOL 2 YLAMINE HYDROIODIDE; 8H INDENO[1,2 D]THIAZOL 2 YLAMINE DERIVATIVE; ADENOSINE A1 RECEPTOR; ADENOSINE A1 RECEPTOR AGONIST; ADENOSINE A2A RECEPTOR; ADENOSINE A3 RECEPTOR; BORONIC ACID DERIVATIVE; INDANONE DERIVATIVE; IODINE; PALLADIUM; RECEPTOR SUBTYPE; THIOUREA; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CARDIOVASCULAR DISEASE; CATALYSIS; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; EMBRYO; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY DISEASE; NEUROLOGIC DISEASE; NONHUMAN; POLYMERIZATION;

ALLOSTERIC REGULATION; AMINES; ANIMALS; BINDING, COMPETITIVE; CELL LINE; CRICETINAE; CRICETULUS; HUMANS; INDENES; RADIOLIGAND ASSAY; RECEPTOR, ADENOSINE A1; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 23444458267     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm049132j     Document Type: Article

References (23)

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