Murine lupus susceptibility locus Sle2 activates DNA-reactive B cells through two sub-loci with distinct phenotypes

Genes and Immunity

Volumn 12, Issue 3, 2011, Pages 199-207

  Zeumer, L ^a   Sang, A ^a   Niu, H ^a,b   Morel, L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

autoantibodies; B cells; genetics; lupus; marginal zone

Indexed keywords

AUTOANTIBODY; DNA ANTIBODY; PROTEIN SLE 2; PROTEIN SLE 2 A; PROTEIN SLE 2 B; PROTEIN SLE 2 C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL DIFFERENTIATION; GENE EXPRESSION; GENE LOCATION; GENETIC SUSCEPTIBILITY; LUPUS ERYTHEMATOSUS NEPHRITIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ANTIBODIES, ANTINUCLEAR; B-LYMPHOCYTES; DISEASE MODELS, ANIMAL; FEMALE; GENE ORDER; GENETIC PREDISPOSITION TO DISEASE; IMMUNOGLOBULIN ISOTYPES; LUPUS ERYTHEMATOSUS, SYSTEMIC; LYMPHOCYTE ACTIVATION; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED NZB; MICE, TRANSGENIC; PHENOTYPE; QUANTITATIVE TRAIT LOCI; SPLEEN;

MURINAE; MUS;

EID: 79955469590     PISSN: 14664879     EISSN: 14765470     Source Type: Journal    
DOI: 10.1038/gene.2010.69     Document Type: Article

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