메뉴 건너뛰기




Volumn 38, Issue 11, 2008, Pages 3028-3040

Defective B-cell response to T-dependent immunization in lupus-prone mice

Author keywords

Animal models; Antibodies; Autoimmunity; B cells

Indexed keywords

FC RECEPTOR IIB; IMMUNOGLOBULIN; KEYHOLE LIMPET HEMOCYANIN; T LYMPHOCYTE ANTIGEN; FC RECEPTOR;

EID: 58149330303     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838417     Document Type: Article
Times cited : (16)

References (41)
  • 1
    • 0035555161 scopus 로고    scopus 로고
    • Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity
    • Lipsky, P. E., Systemic lupus erythematosus: An autoimmune disease of B cell hyperactivity. Nat. Immunol. 2001. 2: 764-766.
    • (2001) Nat. Immunol , vol.2 , pp. 764-766
    • Lipsky, P.E.1
  • 2
    • 0028292951 scopus 로고
    • Genetic and structural evidence for antigen selection of anti-DNA antibodies
    • Radic, M. Z. and Weigert, M., Genetic and structural evidence for antigen selection of anti-DNA antibodies. Ann. Rev. Immunol. 1994. 12: 487-520.
    • (1994) Ann. Rev. Immunol , vol.12 , pp. 487-520
    • Radic, M.Z.1    Weigert, M.2
  • 3
    • 0032797012 scopus 로고    scopus 로고
    • Autoreactive T cells in murine lupus - Origins and roles in autoantibody production
    • Craft, J., Peng, S., Fujii, T., Okada, M. and Fatenejad, S., Autoreactive T cells in murine lupus - Origins and roles in autoantibody production. Immunol. Res. 1999. 19: 245-257.
    • (1999) Immunol. Res , vol.19 , pp. 245-257
    • Craft, J.1    Peng, S.2    Fujii, T.3    Okada, M.4    Fatenejad, S.5
  • 4
    • 0027245507 scopus 로고
    • Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen
    • Burlingame, R. W., Rubin, R. L., Balderas, R. S. and Theofilopoulos, A. N., Genesis and evolution of antichromatin autoantibodies in murine lupus implicates T-dependent immunization with self antigen. J. Clin. Invest. 1993. 91: 1687-1696.
    • (1993) J. Clin. Invest , vol.91 , pp. 1687-1696
    • Burlingame, R.W.1    Rubin, R.L.2    Balderas, R.S.3    Theofilopoulos, A.N.4
  • 5
    • 0037144519 scopus 로고    scopus 로고
    • Evolution of autoantibody responses via somatic hypermutation outside of germinal centers
    • William, J., Euler, C., Christensen, S. and Shlomchik, M. J., Evolution of autoantibody responses via somatic hypermutation outside of germinal centers. Science 2002. 297: 2066-2070.
    • (2002) Science , vol.297 , pp. 2066-2070
    • William, J.1    Euler, C.2    Christensen, S.3    Shlomchik, M.J.4
  • 6
    • 37549049335 scopus 로고    scopus 로고
    • Antichromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites
    • Herlands, R. A., William, J., Hershberg, U. and Shlomchik, M. J., Antichromatin antibodies drive in vivo antigen-specific activation and somatic hypermutation of rheumatoid factor B cells at extrafollicular sites. Eur. J. Immunol. 2007. 37: 3339-3351.
    • (2007) Eur. J. Immunol , vol.37 , pp. 3339-3351
    • Herlands, R.A.1    William, J.2    Hershberg, U.3    Shlomchik, M.J.4
  • 8
    • 0028445340 scopus 로고
    • Polygenic control of susceptibility to murine systemic lupus erythematosus
    • Morel, L., Rudofsky, U. H., Longmate, J. A., Schiffenbauer, J. and Wakeland, E. K., Polygenic control of susceptibility to murine systemic lupus erythematosus. Immunity 1994. 1: 219-229.
    • (1994) Immunity , vol.1 , pp. 219-229
    • Morel, L.1    Rudofsky, U.H.2    Longmate, J.A.3    Schiffenbauer, J.4    Wakeland, E.K.5
  • 9
    • 1342300520 scopus 로고    scopus 로고
    • Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice
    • Liang, Z. Y., Xie, C., Chen, C., Kreska, D., Hsu, K., Li, L. N., Zhou, X. J. and Mohan, C., Pathogenic profiles and molecular signatures of antinuclear autoantibodies rescued from NZM2410 lupus mice. J. Exp. Med. 2004. 199: 381-398.
    • (2004) J. Exp. Med , vol.199 , pp. 381-398
    • Liang, Z.Y.1    Xie, C.2    Chen, C.3    Kreska, D.4    Hsu, K.5    Li, L.N.6    Zhou, X.J.7    Mohan, C.8
  • 11
    • 0025726702 scopus 로고
    • In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
    • Jacob, J., Kassir, R. and Kelsoe, G., In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations. J. Exp. Med. 1991. 173: 1165-1175.
    • (1991) J. Exp. Med , vol.173 , pp. 1165-1175
    • Jacob, J.1    Kassir, R.2    Kelsoe, G.3
  • 12
    • 33746062790 scopus 로고    scopus 로고
    • STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus
    • Xu, Z., Duan, B., Croker, B. P. and Morel, L., STAT4 deficiency reduces autoantibody production and glomerulonephritis in a mouse model of lupus. Clin. Immunol. 2006. 120: 189-198.
    • (2006) Clin. Immunol , vol.120 , pp. 189-198
    • Xu, Z.1    Duan, B.2    Croker, B.P.3    Morel, L.4
  • 14
    • 3142658576 scopus 로고    scopus 로고
    • XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
    • Shaffer, A. L., Shapiro-Shelef, M., Iwakoshi, N. N., Lee, A. H., Qian, S. B., Zhao, H., Yu, X. et al., XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004. 21: 81-93.
    • (2004) Immunity , vol.21 , pp. 81-93
    • Shaffer, A.L.1    Shapiro-Shelef, M.2    Iwakoshi, N.N.3    Lee, A.H.4    Qian, S.B.5    Zhao, H.6    Yu, X.7
  • 15
    • 18444395232 scopus 로고    scopus 로고
    • Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program
    • Shaffer, A. L., Lin, K. I., Kuo, T. C., Yu, X., Hurt, E. M., Rosenwald, A., Giltnane, J. M. et al., Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. Immunity 2002. 17: 51-62.
    • (2002) Immunity , vol.17 , pp. 51-62
    • Shaffer, A.L.1    Lin, K.I.2    Kuo, T.C.3    Yu, X.4    Hurt, E.M.5    Rosenwald, A.6    Giltnane, J.M.7
  • 17
    • 35548937869 scopus 로고    scopus 로고
    • Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production
    • Rahman, Z. S. M., Niu, H., Perry, D., Wakeland, E., Manser, T. and Morel, L., Expression of the autoimmune Fcgr2b NZW allele fails to be upregulated in germinal center B cells and is associated with increased IgG production. Genes Immun. 2007. 8: 604-612.
    • (2007) Genes Immun , vol.8 , pp. 604-612
    • Rahman, Z.S.M.1    Niu, H.2    Perry, D.3    Wakeland, E.4    Manser, T.5    Morel, L.6
  • 18
    • 0020541774 scopus 로고
    • Isotypic profiles and other fine characteristics of immune responses to exogenous thymus-dependent and -independent antigens by mice with lupus syndromes
    • Park, C. L., Balderas, R. S., Fieser, T. M., Slack, J. H., Prud'homme, G. J., Dixon, F. J. and Theofilopoulos, A. N., Isotypic profiles and other fine characteristics of immune responses to exogenous thymus-dependent and -independent antigens by mice with lupus syndromes. J. Immunol. 1983. 130: 2161-2167.
    • (1983) J. Immunol , vol.130 , pp. 2161-2167
    • Park, C.L.1    Balderas, R.S.2    Fieser, T.M.3    Slack, J.H.4    Prud'homme, G.J.5    Dixon, F.J.6    Theofilopoulos, A.N.7
  • 19
    • 0023938477 scopus 로고
    • Defective primary and secondary IgG responses to thymic-dependent antigens in autoimmune PN mice
    • Walker, S. E., Defective primary and secondary IgG responses to thymic-dependent antigens in autoimmune PN mice. J. Immunol. 1988. 140: 3426-3433.
    • (1988) J. Immunol , vol.140 , pp. 3426-3433
    • Walker, S.E.1
  • 20
    • 16544372643 scopus 로고    scopus 로고
    • Correlation of circulating CD27high plasma cells and disease activity in systemic lupus erythematosus
    • Dorner, T. and Lipsky, P. E., Correlation of circulating CD27high plasma cells and disease activity in systemic lupus erythematosus. Lupus 2004. 13: 283-289.
    • (2004) Lupus , vol.13 , pp. 283-289
    • Dorner, T.1    Lipsky, P.E.2
  • 22
    • 0031179651 scopus 로고    scopus 로고
    • Genetic dissection of systemic lupus erythematosus pathogenesis - Sle2 on murine chromosome 4 leads to B cell hyperactivity
    • Mohan, C., Morel, L., Yang, P. and Wakeland, E. K., Genetic dissection of systemic lupus erythematosus pathogenesis - Sle2 on murine chromosome 4 leads to B cell hyperactivity. J. Immunol. 1997. 159: 454-465.
    • (1997) J. Immunol , vol.159 , pp. 454-465
    • Mohan, C.1    Morel, L.2    Yang, P.3    Wakeland, E.K.4
  • 23
    • 0037290768 scopus 로고    scopus 로고
    • Epitope dominance, competition and T cell affinity maturation
    • Kedl, R. M., Kappler, J. W. and Marrack, P., Epitope dominance, competition and T cell affinity maturation. Curr. Opin. Immunol. 2003. 15: 120-127.
    • (2003) Curr. Opin. Immunol , vol.15 , pp. 120-127
    • Kedl, R.M.1    Kappler, J.W.2    Marrack, P.3
  • 24
    • 38849101739 scopus 로고    scopus 로고
    • Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms
    • Cuda, C. M., Wan, S., Sobel, E. S., Croker, B. P. and Morel, L., Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms. J. Immunol. 2007. 179: 7439-7447.
    • (2007) J. Immunol , vol.179 , pp. 7439-7447
    • Cuda, C.M.1    Wan, S.2    Sobel, E.S.3    Croker, B.P.4    Morel, L.5
  • 25
    • 33749685322 scopus 로고    scopus 로고
    • Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling
    • Omori, S. A., Cato, M. H., nzelon-Mills, A., Puri, K. D., Shapiro-Shelef, M., Calame, K. and Rickert, R. C., Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. Immunity 2006. 25: 545-557.
    • (2006) Immunity , vol.25 , pp. 545-557
    • Omori, S.A.1    Cato, M.H.2    nzelon-Mills, A.3    Puri, K.D.4    Shapiro-Shelef, M.5    Calame, K.6    Rickert, R.C.7
  • 26
    • 34547687662 scopus 로고    scopus 로고
    • Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus
    • Wu, T., Qin, X., Kurepa, Z., Kumar, K. R., Liu, K., Kanta, H., Zhou, X. J. et al., Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. J. Clin. Invest. 2007. 117: 2186-2196.
    • (2007) J. Clin. Invest , vol.117 , pp. 2186-2196
    • Wu, T.1    Qin, X.2    Kurepa, Z.3    Kumar, K.R.4    Liu, K.5    Kanta, H.6    Zhou, X.J.7
  • 27
    • 2942635727 scopus 로고    scopus 로고
    • Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice
    • Hoyer, B. F., Moser, K., Hauser, A. E., Peddinghaus, A., Voigt, C., Eilat, D., Radbruch, A. et al., Short-lived plasmablasts and long-lived plasma cells contribute to chronic humoral autoimmunity in NZB/W mice. J. Exp. Med. 2004. 199: 1577-1584.
    • (2004) J. Exp. Med , vol.199 , pp. 1577-1584
    • Hoyer, B.F.1    Moser, K.2    Hauser, A.E.3    Peddinghaus, A.4    Voigt, C.5    Eilat, D.6    Radbruch, A.7
  • 28
    • 33847375266 scopus 로고    scopus 로고
    • Expression profile of FcγRIIb on leukocytes and its dysregulation in systemic lupus erythematosus
    • Su, K., Yang, H., Li, X., Li, X., Gibson, A. W., Cafardi, J. M., Zhou, T. et al., Expression profile of FcγRIIb on leukocytes and its dysregulation in systemic lupus erythematosus. J. Immunol. 2007. 178: 3272-3280.
    • (2007) J. Immunol , vol.178 , pp. 3272-3280
    • Su, K.1    Yang, H.2    Li, X.3    Li, X.4    Gibson, A.W.5    Cafardi, J.M.6    Zhou, T.7
  • 29
    • 12844251399 scopus 로고    scopus 로고
    • Restoration of tolerance in lupus by targeted inhibitory receptor expression
    • Mcgaha, T. L., Sorrentino, B. and Ravetch, J. V., Restoration of tolerance in lupus by targeted inhibitory receptor expression. Science 2005. 307: 590-593.
    • (2005) Science , vol.307 , pp. 590-593
    • Mcgaha, T.L.1    Sorrentino, B.2    Ravetch, J.V.3
  • 30
    • 0035652286 scopus 로고    scopus 로고
    • Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein
    • Boackle, S. A., Holers, V. M., Chen, X. J., Szakonyi, G., Karp, D. R., Wakeland, E. K. and Morel, L., Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity 2001. 15: 775-785.
    • (2001) Immunity , vol.15 , pp. 775-785
    • Boackle, S.A.1    Holers, V.M.2    Chen, X.J.3    Szakonyi, G.4    Karp, D.R.5    Wakeland, E.K.6    Morel, L.7
  • 31
    • 0034193061 scopus 로고    scopus 로고
    • Humoral immune responses in Cr2(-/-) mice: Enhanced affinity maturation but impaired antibody persistence
    • Chen, Z. B., Koralov, S. B., Gendelman, M., Carroll, M. C. and Kelsoe, G., Humoral immune responses in Cr2(-/-) mice: Enhanced affinity maturation but impaired antibody persistence. J. Immunol. 2000. 164: 4522-4532.
    • (2000) J. Immunol , vol.164 , pp. 4522-4532
    • Chen, Z.B.1    Koralov, S.B.2    Gendelman, M.3    Carroll, M.C.4    Kelsoe, G.5
  • 34
    • 17144418984 scopus 로고    scopus 로고
    • Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1
    • Gatto, D., Pfister, T., Jegerlehner, A., Martin, S. W., Kopf, M. and Bachmann, M. F., Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1. J. Exp. Med. 2005. 201: 993-1005.
    • (2005) J. Exp. Med , vol.201 , pp. 993-1005
    • Gatto, D.1    Pfister, T.2    Jegerlehner, A.3    Martin, S.W.4    Kopf, M.5    Bachmann, M.F.6
  • 35
    • 0035852650 scopus 로고    scopus 로고
    • The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes
    • Morel, L., Blenman, K. R., Croker, B. P. and Wakeland, E. K., The major murine systemic lupus erythematosus susceptibility locus, Sle1, is a cluster of functionally related genes. Proc. Natl. Acad. Sci. USA 2001. 98: 1787-1792.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1787-1792
    • Morel, L.1    Blenman, K.R.2    Croker, B.P.3    Wakeland, E.K.4
  • 36
    • 1342298274 scopus 로고    scopus 로고
    • Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus
    • Croker, B. P., Gilkeson, G. and Morel, L., Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus. Genes Immun. 2003. 4: 575-585.
    • (2003) Genes Immun , vol.4 , pp. 575-585
    • Croker, B.P.1    Gilkeson, G.2    Morel, L.3
  • 37
    • 10344265955 scopus 로고    scopus 로고
    • Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing
    • Wakui, M., Kim, J., Butfiloski, E. J., Morel, L. and Sobel, E. S., Genetic dissection of lupus pathogenesis: Sle3/5 impacts IgH CDR3 sequences, somatic mutations, and receptor editing. J. Immunol. 2004. 173: 7368-7376.
    • (2004) J. Immunol , vol.173 , pp. 7368-7376
    • Wakui, M.1    Kim, J.2    Butfiloski, E.J.3    Morel, L.4    Sobel, E.S.5
  • 38
    • 33746697724 scopus 로고    scopus 로고
    • Why have rheumatologists been reluctant to vaccinate patients with systemic lupus erythematosus?
    • Mercado, U., Why have rheumatologists been reluctant to vaccinate patients with systemic lupus erythematosus? J. Rheumatol. 2006. 33: 1469-1471.
    • (2006) J. Rheumatol , vol.33 , pp. 1469-1471
    • Mercado, U.1
  • 39
    • 33947525568 scopus 로고    scopus 로고
    • Immunizing patients with systemic lupus erythematosus: A review of effectiveness and safety
    • O'Neill, S. G. and Isenberg, D. A., Immunizing patients with systemic lupus erythematosus: A review of effectiveness and safety. Lupus 2006. 15: 778-783.
    • (2006) Lupus , vol.15 , pp. 778-783
    • O'Neill, S.G.1    Isenberg, D.A.2
  • 40
    • 0032520923 scopus 로고    scopus 로고
    • Genetic dissection of SLE pathogenesis - Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes
    • Mohan, C., Alas, E., Morel, L., Yang, P. and Wakeland, E. K., Genetic dissection of SLE pathogenesis - Sle1 on murine chromosome 1 leads to a selective loss of tolerance to H2A/H2B/DNA subnucleosomes. J. Clin. Invest. 1998. 101: 1362-1372.
    • (1998) J. Clin. Invest , vol.101 , pp. 1362-1372
    • Mohan, C.1    Alas, E.2    Morel, L.3    Yang, P.4    Wakeland, E.K.5
  • 41
    • 33845805695 scopus 로고    scopus 로고
    • Lupus resistance is associated with marginal zone abnormalities in an NZM murine model
    • Duan, B., Croker, B. P. and Morel, L., Lupus resistance is associated with marginal zone abnormalities in an NZM murine model. Lab. Invest. 2007. 87: 14-28.
    • (2007) Lab. Invest , vol.87 , pp. 14-28
    • Duan, B.1    Croker, B.P.2    Morel, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.