Synthesis and in vitro/in vivo evaluation of 99mTc-labeled folate conjugates for folate receptor imaging

Nuclear Medicine and Biology

Volumn 38, Issue 4, 2011, Pages 557-565

  Lu, Jie ^a   Pang, Yan ^a   Xie, Fang ^a   Guo, Hongjuan ^a   Li, Yan ^a,b   Yang, Zhi ^b   Wang, Xuebin ^a  

^a BEIJING NORMAL UNIVERSITY   (China)

^b PEKING UNIVERSITY CANCER HOSPITAL AND INSTITUTE   (China)

Author keywords

Biodistribution; Folate conjugate; Folate receptor; KB tumor; Technetium 99m

Indexed keywords

6 HYDRAZINONICOTINIC ACID; 6 HYDRAZINONICOTINIC ACID FOLATE TC 99M; DIPHENYLPHOSPHINOBENZENE 3 SULFONIC ACID; FOLATE RECEPTOR; N TRIS(HYDROXYMETHYL)METHYLGLYCINE; RADIOPHARMACEUTICAL AGENT; TECHNETIUM 99M; TRISODIUM TRIPHENYLPHOSPHOINE 3,3',3'' TRISULFONATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG EXCRETION; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; GASTROINTESTINAL TRACT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; ISOTOPE LABELING; LIGAND BINDING; MOUSE; NONHUMAN; PURIFICATION;

ANIMALS; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; HUMANS; KB CELLS; LIGANDS; MICE; MOLECULAR IMAGING; ORGANOTECHNETIUM COMPOUNDS; RADIOCHEMISTRY;

EID: 79955469575     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2010.11.007     Document Type: Article

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