Effects of the antifolates pemetrexed and CB3717 on the tissue distribution of 99mTc-EC20 in xenografted and syngeneic tumor-bearing mice

Molecular Pharmaceutics

Volumn 7, Issue 2, 2010, Pages 597-604

  Müller, Cristina ^a   Reddy, Joseph A ^b   Leamon, Christopher P ^b   Schibli, Roger ^a,c  

^a ETH Zurich   (Switzerland)

^b Endocyte Inc   (United States)

^c ETH ZURICH   (Switzerland)

Author keywords

99mTc EC20; Antifolate; CB3717; Folate receptor; Folic acid; Pemetrexed

Indexed keywords

10 PROPARGYL 5,8 DIDEAZAFOLIC ACID; EC 20; FOLATE RECEPTOR; FOLIC ACID; FOLIC ACID DERIVATIVE; PEMETREXED; TECHNETIUM 99M; TRITIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; ISOGRAFT; MOUSE; NONHUMAN; PRIORITY JOURNAL; TISSUE DISTRIBUTION; TUMOR XENOGRAFT;

ANIMALS; CELL LINE, TUMOR; FEMALE; FOLIC ACID; FOLIC ACID ANTAGONISTS; GLUTAMATES; GUANINE; HUMANS; KIDNEY; MICE; MICE, NUDE; OLIGOPEPTIDES; ORGANOTECHNETIUM COMPOUNDS; QUINAZOLINES; TECHNETIUM; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77950571314     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp900296k     Document Type: Article

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