Induction of G1 arrest and apoptosis in androgen-dependent human prostate cancer by Kuguacin J, a triterpenoid from Momordica charantia leaf

Cancer Letters

Volumn 306, Issue 2, 2011, Pages 142-150

  Pitchakarn, Pornsiri ^a,d   Suzuki, Shugo ^a   Ogawa, Kumiko ^a,b   Pompimon, Wilart ^c   Takahashi, Satoru ^a   Asamoto, Makoto ^a   Limtrakul, Pornngarm ^d   Shirai, Tomoyuki ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^c LAMPANG RAJABHAT UNIVERSITY   (Thailand)

^d Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

Apoptosis; Bitter melon; Cell cycle; Kuguacin j; Prostate cancer

Indexed keywords

ACETIC ACID ETHYL ESTER; ANDROGEN RECEPTOR; CASPASE 3; CHLOROFORM; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; CYCLINE; ETHER; HEXANE; KUGUACIN J; MOMORDICA CHARANTIA EXTRACT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROSTATE SPECIFIC ANTIGEN; PROTEIN BAD; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P21; PROTEIN P27; PROTEIN P53; SURVIVIN; TRITERPENOID; TUBULIN; UNCLASSIFIED DRUG;

ANDROGEN DEPENDENT PROSTATE CANCER; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; ENZYME DEGRADATION; GROWTH INHIBITION; HUMAN; HUMAN CELL; MALE; PLANT LEAF; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN ANALYSIS; PROTEIN SYNTHESIS INHIBITION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; SOLVENT EXTRACTION;

APOPTOSIS; BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL PROLIFERATION; G1 PHASE; HUMANS; MALE; MOMORDICA CHARANTIA; NEOPLASMS, HORMONE-DEPENDENT; PLANT LEAVES; PROSTATIC NEOPLASMS; TRITERPENES; TUMOR CELLS, CULTURED;

CUCUMIS; MOMORDICA CHARANTIA;

EID: 79955465233     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2011.02.041     Document Type: Article

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