Kuguacins F-S, cucurbitane triterpenoids from Momordica charantia

Phytochemistry

Volumn 70, Issue 1, 2009, Pages 133-140

  Chen, Jian Chao ^a   Liu, Wu Qing ^b   Lu, Lu ^a,c   Qiu, Ming Hua ^a   Zheng, Yong Tang ^b   Yang, Liu Meng ^b   Zhang, Xian Min ^a   Zhou, Lin ^a   Li, Zhong Rong ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b KUNMING INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

Cucurbitaceae; Cucurbitane triterpenoids; Kuguacins F S; Momordica charantia

Indexed keywords

TRITERPENE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; MOMORDICA CHARANTIA; PLANT;

MODELS, MOLECULAR; MOLECULAR STRUCTURE; MOMORDICA CHARANTIA; PLANT COMPONENTS, AERIAL; TRITERPENES;

CUCUMIS SATIVUS; CUCURBITACEAE; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MOMORDICA CHARANTIA;

EID: 59049083730     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2008.10.011     Document Type: Article

References (21)

1. Akihisa T., Higo N., Tokuda H., Ukiya M., Akazawa H., Tochigi Y., Kimura Y., Suzuki T., and Nishino H. Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects. J. Nat. Prod. 70 (2007) 1233-1239
2. Begum S., Ahmed M., Siddiqui B.S., Khan A., Saify Z.S., and Arif M. Triterpenes, a sterol and a monocyclic alcohol from Momordica charantia. Phytochemistry 44 (1997) 1313-1320
3. Chang C.I., Chen C.R., Liao Y.W., Cheng H.L., Chen Y.C., and Chou C.H. Cucurbitane-type triterpenoids from Momordica charantia. J. Nat. Prod. 69 (2006) 1168-1171
4. Chen J.C., Tian R.R., Qiu M.H., Lu L., Zheng Y.T., and Zhang Z.Q. Trinorcucurbitane and cucurbitane triterpenoids from the roots of Momordica charantia. Phytochemistry 69 (2008) 1043-1048
5. Chen J.C., Zhang G.H., Zhang Z.Q., Qiu M.H., Zheng Y.T., Yang L.M., and Yu K.B. Octanorcucurbitane and cucurbitane triterpenoids from the tubers of Hemsleya endecaphylla with HIV-1 inhibitory activity. J. Nat. Prod. 71 (2008) 153-155
6. Fatope M.O., Takeda Y., Yamashita H., Okabe H., and Yamauchi T. New cucurbitane triterpenoids from Momordica charantia. J. Nat. Prod. 53 (1990) 1491-1497
7. Harinantenaina L., Tanaka M., Takaoka S., Oda M., Mogami O., Uchida M., and Asakawa Y. Momordica charantia constituents and antidiabetic screening of the isolated major compounds. Chem. Pharm. Bull. 54 (2006) 1017-1021
8. Kanchanapoom T., Kasai R., and Yamasaki K. Cucurbitane and octanorcucurbitane glycosides from fruits of Trichosanthes tricuspidata. Phytochemistry 59 (2002) 215-228
9. Kimura Y., Akihisa T., Yuasa N., Ukiya M., Suzuki T., Toriyama M., Motohashi S., and Tokuda H. Cucurbitane-type triterpenoids from the fruit of Momordica charantia. J. Nat. Prod. 68 (2005) 807-809
10. Li Q.Y., Chen H.B., Liu Z.M., Wang B., and Zhao Y.Y. Cucurbitane triterpenoids from Momordica charantia. Magn. Reson. Chem. 45 (2007) 451-456
11. Matsuda H., Nakamura S., Murakami T., and Yoshikawa M. Structures of new cucurbitane-type triterpenes and glycosides, karavilagenins D and E, and karavilosides VI, VII, VIII, IX, X, and XI, from the fruit of Momordica charantia. Heterocycles 71 (2007) 331-341
12. Miyahara Y., Okabe H., and Yamauchi T. Studies on the constituents of Momordica charantia L. II. Isolation and characterization of minor seed glycosides, momordicosides C, D and E. Chem. Pharm. Bull. 29 (1981) 1561-1566
13. Mulholland D.A., Sewram V., Osborne R., Pegel K.H., and Connolly J.D. Cucurbitane triterpenoids from the leaves of Momordica foetida. Phytochemistry 45 (1997) 391-395
14. Murakami T., Emoto A., Matsuda H., and Yoshikawa M. Medicinal foodstuffs. XXI. Structures of new cucurbitane-type triterpene glycosides, goyaglycosides-a, -b, -c, -d, -e, -f, -g, and -h, and new oleanane-type triterpene saponins, goyasaponins I, II, and III, from the fresh fruit of Japanese Momordica charantia L. Chem. Pharm. Bull. 49 (2001) 54-63
15. Nakamura S., Murakami T., Nakamura J., Kobayashi H., Matsuda H., and Yoshikawa M. Structures of new cucurbitane-type triterpenes and glycosides, karavilagenins and karavilosides, from the dried fruit of Momordica charantia L. in Sri Lanka. Chem. Pharm. Bull. 54 (2006) 1545-1550
16. Okabe H., Miyahara Y., Yamauchi T., Miyahara K., and Kawasaki T. Studies on the constituents of Momordica charantia L. I. Isolation and characterization of momordicosides A and B, glycosides of a pentahydroxy-cucurbitane triterpene. Chem. Pharm. Bull. 28 (1980) 2753-2762
17. 2 and I. Chem. Pharm. Bull. 30 (1982) 3977-3986
18. Okabe H., Miyahara Y., and Yamauchi T. Studies on the constituents of Momordica charantia L. IV. Characterization of the new cucurbitacin glycosides of the immature fruits. (2) Structures of the bitter glycosides, momordicosides K and L. Chem. Pharm. Bull. 30 (1982) 4334-4340
19. Yasuda M., Iwamoto M., Okabe H., and Yamauchi T. Structures of momordicines I, II and III, the bitter principles in the leaves and vines of Momordica charantia L. Chem. Pharm. Bull. 32 (1984) 2044-2047
20. Zhang G.H., Wang Q., Chen J.J., Zhang X.M., Tam S.C., and Zheng Y.T. Anti-HIV-1 effect of scutellarin. Biochem. Biophys. Res. Commun. 334 (2005) 812-816
21. Zhu Z.J., Zhong Z.C., Luo Z.Y., and Xiao Z.Y. Studies on the active constituents of Momordica charantia L. Acta Pharm. Sin. 25 (1990) 898-903