Progression of Heart Failure Was Suppressed by Inhibition of Apoptosis Signal-Regulating Kinase 1 Via Transcoronary Gene Transfer

Journal of the American College of Cardiology

Volumn 50, Issue 5, 2007, Pages 453-462

  Hikoso, Shungo ^a   Ikeda, Yasuhiro ^b   Yamaguchi, Osamu ^a   Takeda, Toshihiro ^a   Higuchi, Yoshiharu ^a   Hirotani, Shinichi ^a   Kashiwase, Kazunori ^a   Yamada, Michio ^b   Asahi, Michio ^a   Matsumura, Yasushi ^a   Nishida, Kazuhiko ^a   Matsuzaki, Masunori ^b   Hori, Masatsugu ^a   Otsu, Kinya ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; CALPAIN; DELTA SARCOGLYCAN; SARCOGLYCAN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; DISEASE COURSE; GENE EXPRESSION; GENE TRANSFER; GENETIC DISORDER; HEART FAILURE; IN VIVO GENE TRANSFER; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; CRICETINAE; DEPENDOVIRUS; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; GENE TRANSFER TECHNIQUES; HEART FAILURE, CONGESTIVE; MAP KINASE KINASE KINASE 5; MYOCYTES, CARDIAC; TRANSGENES; TREATMENT OUTCOME; VENTRICULAR REMODELING;

EID: 34447620317     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2007.03.053     Document Type: Article

References (22)

1. Opie L.H., Commerford P.J., Gersh B.J., and Pfeffer M.A. Controversies in ventricular remodelling. Lancet 367 (2006) 356-367
2. Hayashidani S., Tsutui H., Shiomi T., et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates left ventricular remodeling and failure after experimental myocardial infarction. Circulation 108 (2003) 2134-2140
3. Ichijo H., Nishida E., Irie K., et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275 (1997) 90-94
4. Hirotani S., Otsu K., Nishida K., et al. Involvement of nuclear factor-kappaB and apoptosis signal-regulating kinase 1 in G-protein-coupled receptor agonist-induced cardiomyocyte hypertrophy. Circulation 105 (2002) 509-515
5. Yamaguchi O., Higuchi Y., Hirotani S., et al. Targeted deletion of apoptosis signal-regulating kinase 1 attenuates left ventricular remodeling. Proc Natl Acad Sci U S A 100 (2003) 15883-15888
6. Watanabe T., Otsu K., Takeda T., et al. Apoptosis signal-regulating kinase 1 is involved not only in apoptosis but also in non-apoptotic cardiomyocyte death. Biochem Biophys Res Commun 333 (2005) 562-567
7. Sakamoto A., Ono K., Abe M., et al. Both hypertrophic and dilated cardiomyopathies are caused by mutation of the same gene, delta-sarcoglycan, in hamster: an animal model of disrupted dystrophin-associated glycoprotein complex. Proc Natl Acad Sci U S A 94 (1997) 13873-13878
8. Tsubata S., Bowles K.R., Vatta M., et al. Mutations in the human delta-sarcoglycan gene in familial and sporadic dilated cardiomyopathy. J Clin Invest 106 (2000) 655-662
9. Ikeda Y., Martone M., Gu Y., et al. Altered membrane proteins and permeability correlate with cardiac dysfunction in cardiomyopathic hamsters. Am J Physiol Heart Circ Physiol 278 (2000) H1362-H1370
10. Toyo-Oka T., Kawada T., Nakata J., et al. Translocation and cleavage of myocardial dystrophin as a common pathway to advanced heart failure: a scheme for the progression of cardiac dysfunction. Proc Natl Acad Sci U S A 101 (2004) 7381-7385
11. 2+-permeable growth factor-regulated channel. J Cell Biol 161 (2003) 957-967
12. Vatta M., Stetson S.J., Jimenez S., et al. Molecular normalization of dystrophin in the failing left and right ventricle of patients treated with either pulsatile or continuous flow-type ventricular assist devices. J Am Coll Cardiol 43 (2004) 811-817
13. Hoshijima M., Ikeda Y., Iwanaga Y., et al. Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 8 (2002) 864-871
14. Matsumura Y., Saeki E., Otsu K., et al. Intracellular calcium level required for calpain activation in a single myocardial cell. J Mol Cell Cardiol 33 (2001) 1133-1142
15. Kawada T., Masui F., Tezuka A., et al. A novel scheme of dystrophin disruption for the progression of advanced heart failure. Biochim Biophys Acta 1751 (2005) 73-81
16. Cottin P., Poussard S., Mornet D., et al. In vitro digestion of dystrophin by calcium-dependent proteases, calpains I and II. Biochimie 74 (1992) 565-570
17. Goll D.E., Thompson V.F., Li H., Wei W., and Cong J. The calpain system. Physiol Rev 83 (2003) 731-801
18. Foo R.S., Mani K., and Kitsis R.N. Death begets failure in the heart. J Clin Invest 115 (2005) 565-571
19. Fan G.C., Yuan Q., Song G., et al. Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1. Circ Res 99 (2006) 1233-1242
20. Spencer M.J., Croall D.E., and Tidball J.G. Calpains are activated in necrotic fibers from mdx dystrophic mice. J Biol Chem 270 (1995) 10909-10914
21. Barta J., Toth A., Edes I., et al. Calpain-1-sensitive myofibrillar proteins of the human myocardium. Mol Cell Biochem 278 (2005) 1-8
22. Gil-Parrado S., Fernandez-Montalvan A., Assfalg-Machleidt I., et al. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem 277 (2002) 27217-27226