Structure-based design of a heptavalent anthrax toxin inhibitor

Biomacromolecules

Volumn 12, Issue 3, 2011, Pages 791-796

  Joshi, Amit ^a   Kate, Sandesh ^a   Poon, Vincent ^c   Mondal, Dhananjoy ^a   Boggara, Mohan B ^a   Saraph, Arundhati ^a   Martin, Jacob T ^a   McAlpine, Ryan ^b   Day, Ryan ^b   Garcia, Angel E ^b   Mogridge, Jeremy ^c   Kane, Ravi S ^a  

^a Rensselaer Polytechnic Institute   (United States)

^b RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRAX TOXINS; AZIDE-ALKYNE CYCLOADDITION; BIOLOGICAL TARGETS; CLICK CHEMISTRY; COMPUTATIONAL DOCKINGS; CYCLODEXTRIN CORE; EXPERIMENTAL STUDIES; IN-VITRO; IN-VIVO; INHIBITORY PEPTIDES; STRUCTURE-BASED; STRUCTURE-BASED DRUG DESIGN;

ACETYLENE; BIOCHEMISTRY; BIOCOMPATIBILITY; DESIGN; LIGANDS; OLIGOMERS; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES; POLYETHYLENES; SCAFFOLDS; THERMOPLASTICS; TOXIC MATERIALS;

BINDING SITES;

ALKYNE; ANTHRAX TOXIN; ANTITOXIN; AZIDE; BETA CYCLODEXTRIN; COPPER; HEPTAVALENT ANTHRAX TOXIN INHIBITOR; MACROGOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BINDING SITE; BIOCOMPATIBILITY; CATALYSIS; CONTROLLED STUDY; CYCLOADDITION; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG TARGETING; IN VITRO STUDY; IN VIVO STUDY; MOLECULAR DOCKING; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; RAT;

ANTIGENS, BACTERIAL; ANTITOXINS; BACTERIAL TOXINS; BINDING SITES; CYCLODEXTRINS; DRUG DESIGN; DRUG STABILITY; PEPTIDES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79955447417     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm101396u     Document Type: Article

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