메뉴 건너뛰기




Volumn 6, Issue 4, 2011, Pages

Loss of ATF2 function leads to cranial motoneuron degeneration during embryonic mouse development

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CASPASE; LIPID; MITOGEN ACTIVATED PROTEIN KINASE P38; NEUROFILAMENT H PROTEIN; NEUROFILAMENT M PROTEIN; NEUROFILAMENT PROTEIN; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; ATF2 PROTEIN, MOUSE; DUAL SPECIFICITY PHOSPHATASE;

EID: 79955427294     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019090     Document Type: Article
Times cited : (26)

References (68)
  • 1
    • 0032444348 scopus 로고    scopus 로고
    • Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins
    • Herdegen T, Leah JD, (1998) Inducible and constitutive transcription factors in the mammalian nervous system: control of gene expression by Jun, Fos and Krox, and CREB/ATF proteins. Brain Res Brain Res Rev 28: 370-490.
    • (1998) Brain Res Brain Res Rev , vol.28 , pp. 370-490
    • Herdegen, T.1    Leah, J.D.2
  • 2
    • 0028905076 scopus 로고
    • Transcription factor ATF2 regulation by the JNK signal transduction pathway
    • Gupta S, Campbell D, Derijard B, Davis RJ, (1995) Transcription factor ATF2 regulation by the JNK signal transduction pathway. Science 267: 389-393.
    • (1995) Science , vol.267 , pp. 389-393
    • Gupta, S.1    Campbell, D.2    Derijard, B.3    Davis, R.J.4
  • 3
    • 18444411948 scopus 로고    scopus 로고
    • Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38
    • Ouwens DM, de Ruiter ND, van der Zon GC, Carter AP, Schouten J, et al. (2002) Growth factors can activate ATF2 via a two-step mechanism: phosphorylation of Thr71 through the Ras-MEK-ERK pathway and of Thr69 through RalGDS-Src-p38. Embo J 21: 3782-3793.
    • (2002) Embo J , vol.21 , pp. 3782-3793
    • Ouwens, D.M.1    de Ruiter, N.D.2    van der Zon, G.C.3    Carter, A.P.4    Schouten, J.5
  • 4
    • 0029030855 scopus 로고
    • ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents
    • van Dam H, Wilhelm D, Herr I, Steffen A, Herrlich P, et al. (1995) ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents. Embo J 14: 1798-1811.
    • (1995) Embo J , vol.14 , pp. 1798-1811
    • van Dam, H.1    Wilhelm, D.2    Herr, I.3    Steffen, A.4    Herrlich, P.5
  • 5
    • 0029034251 scopus 로고
    • ATF-2 contains a phosphorylation-dependent transcriptional activation domain
    • Livingstone C, Patel G, Jones N, (1995) ATF-2 contains a phosphorylation-dependent transcriptional activation domain. Embo J 14: 1785-1797.
    • (1995) Embo J , vol.14 , pp. 1785-1797
    • Livingstone, C.1    Patel, G.2    Jones, N.3
  • 6
    • 8844285956 scopus 로고    scopus 로고
    • Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress
    • Hayakawa J, Mittal S, Wang Y, Korkmaz KS, Adamson E, et al. (2004) Identification of promoters bound by c-Jun/ATF2 during rapid large-scale gene activation following genotoxic stress. Mol Cell 16: 521-535.
    • (2004) Mol Cell , vol.16 , pp. 521-535
    • Hayakawa, J.1    Mittal, S.2    Wang, Y.3    Korkmaz, K.S.4    Adamson, E.5
  • 8
    • 0030051528 scopus 로고    scopus 로고
    • MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
    • Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ, (1996) MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 16: 1247-1255.
    • (1996) Mol Cell Biol , vol.16 , pp. 1247-1255
    • Raingeaud, J.1    Whitmarsh, A.J.2    Barrett, T.3    Derijard, B.4    Davis, R.J.5
  • 9
    • 0030703604 scopus 로고    scopus 로고
    • Regulation and function of the JNK subgroup of MAP kinases
    • Minden A, Karin M, (1997) Regulation and function of the JNK subgroup of MAP kinases. Biochim Biophys Acta 1333: F85-104.
    • (1997) Biochim Biophys Acta , vol.1333
    • Minden, A.1    Karin, M.2
  • 10
    • 19444363740 scopus 로고    scopus 로고
    • ATM-dependent phosphorylation of ATF2 is required for the DNA damage response
    • Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, et al. (2005) ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell 18: 577-587.
    • (2005) Mol Cell , vol.18 , pp. 577-587
    • Bhoumik, A.1    Takahashi, S.2    Breitweiser, W.3    Shiloh, Y.4    Jones, N.5
  • 11
    • 13344278032 scopus 로고    scopus 로고
    • Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice
    • Reimold AM, Grusby MJ, Kosaras B, Fries JW, Mori R, et al. (1996) Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice. Nature 379: 262-265.
    • (1996) Nature , vol.379 , pp. 262-265
    • Reimold, A.M.1    Grusby, M.J.2    Kosaras, B.3    Fries, J.W.4    Mori, R.5
  • 12
    • 0033580843 scopus 로고    scopus 로고
    • Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome
    • Maekawa T, Bernier F, Sato M, Nomura S, Singh M, et al. (1999) Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome. J Biol Chem 274: 17813-17819.
    • (1999) J Biol Chem , vol.274 , pp. 17813-17819
    • Maekawa, T.1    Bernier, F.2    Sato, M.3    Nomura, S.4    Singh, M.5
  • 13
    • 34547946030 scopus 로고    scopus 로고
    • Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells
    • Breitwieser W, Lyons S, Flenniken AM, Ashton G, Bruder G, et al. (2007) Feedback regulation of p38 activity via ATF2 is essential for survival of embryonic liver cells. Genes Dev 21: 2069-2082.
    • (2007) Genes Dev , vol.21 , pp. 2069-2082
    • Breitwieser, W.1    Lyons, S.2    Flenniken, A.M.3    Ashton, G.4    Bruder, G.5
  • 14
    • 0008193779 scopus 로고    scopus 로고
    • Persistent phosphorylation of cyclic AMP responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain
    • Hu BR, Fux CM, Martone ME, Zivin JA, Ellisman MH, (1999) Persistent phosphorylation of cyclic AMP responsive element-binding protein and activating transcription factor-2 transcription factors following transient cerebral ischemia in rat brain. Neuroscience 89: 437-452.
    • (1999) Neuroscience , vol.89 , pp. 437-452
    • Hu, B.R.1    Fux, C.M.2    Martone, M.E.3    Zivin, J.A.4    Ellisman, M.H.5
  • 15
    • 33744928608 scopus 로고    scopus 로고
    • Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain
    • Raivich G, Behrens A, (2006) Role of the AP-1 transcription factor c-Jun in developing, adult and injured brain. Prog Neurobiol 78: 347-363.
    • (2006) Prog Neurobiol , vol.78 , pp. 347-363
    • Raivich, G.1    Behrens, A.2
  • 16
    • 0030868260 scopus 로고    scopus 로고
    • Expression of activating transcription factor-2, serum response factor and cAMP/Ca response element binding protein in the adult rat brain following generalized seizures, nerve fibre lesion and ultraviolet irradiation
    • Herdegen T, Blume A, Buschmann T, Georgakopoulos E, Winter C, et al. (1997) Expression of activating transcription factor-2, serum response factor and cAMP/Ca response element binding protein in the adult rat brain following generalized seizures, nerve fibre lesion and ultraviolet irradiation. Neuroscience 81: 199-212.
    • (1997) Neuroscience , vol.81 , pp. 199-212
    • Herdegen, T.1    Blume, A.2    Buschmann, T.3    Georgakopoulos, E.4    Winter, C.5
  • 17
    • 0032570051 scopus 로고    scopus 로고
    • Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury
    • Martin-Villalba A, Winter C, Brecht S, Buschmann T, Zimmermann M, et al. (1998) Rapid and long-lasting suppression of the ATF-2 transcription factor is a common response to neuronal injury. Brain Res Mol Brain Res 62: 158-166.
    • (1998) Brain Res Mol Brain Res , vol.62 , pp. 158-166
    • Martin-Villalba, A.1    Winter, C.2    Brecht, S.3    Buschmann, T.4    Zimmermann, M.5
  • 18
    • 33748655865 scopus 로고    scopus 로고
    • Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite-derived tissues
    • Dubois NC, Hofmann D, Kaloulis K, Bishop JM, Trumpp A, (2006) Nestin-Cre transgenic mouse line Nes-Cre1 mediates highly efficient Cre/loxP mediated recombination in the nervous system, kidney, and somite-derived tissues. Genesis 44: 355-360.
    • (2006) Genesis , vol.44 , pp. 355-360
    • Dubois, N.C.1    Hofmann, D.2    Kaloulis, K.3    Bishop, J.M.4    Trumpp, A.5
  • 19
    • 0034114458 scopus 로고    scopus 로고
    • Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function
    • Tallquist MD, Soriano P, (2000) Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function. Genesis 26: 113-115.
    • (2000) Genesis , vol.26 , pp. 113-115
    • Tallquist, M.D.1    Soriano, P.2
  • 20
    • 38849159501 scopus 로고    scopus 로고
    • Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice
    • Kojima M, Suzuki T, Maekawa T, Ishii S, Sumi-Ichinose C, et al. (2008) Increased expression of tyrosine hydroxylase and anomalous neurites in catecholaminergic neurons of ATF-2 null mice. J Neurosci Res 86: 544-552.
    • (2008) J Neurosci Res , vol.86 , pp. 544-552
    • Kojima, M.1    Suzuki, T.2    Maekawa, T.3    Ishii, S.4    Sumi-Ichinose, C.5
  • 21
    • 2642547405 scopus 로고    scopus 로고
    • Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis
    • Richerson GB, (2004) Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis. Nat Rev Neurosci 5: 449-461.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 449-461
    • Richerson, G.B.1
  • 22
    • 0035516124 scopus 로고    scopus 로고
    • From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
    • Cleveland DW, Rothstein JD, (2001) From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat Rev Neurosci 2: 806-819.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 806-819
    • Cleveland, D.W.1    Rothstein, J.D.2
  • 23
    • 0036789845 scopus 로고    scopus 로고
    • Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis
    • Cutler RG, Pedersen WA, Camandola S, Rothstein JD, Mattson MP, (2002) Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis. Ann Neurol 52: 448-457.
    • (2002) Ann Neurol , vol.52 , pp. 448-457
    • Cutler, R.G.1    Pedersen, W.A.2    Camandola, S.3    Rothstein, J.D.4    Mattson, M.P.5
  • 24
    • 0031458813 scopus 로고    scopus 로고
    • Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling
    • Ericson J, Rashbass P, Schedl A, Brenner-Morton S, Kawakami A, et al. (1997) Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling. Cell 90: 169-180.
    • (1997) Cell , vol.90 , pp. 169-180
    • Ericson, J.1    Rashbass, P.2    Schedl, A.3    Brenner-Morton, S.4    Kawakami, A.5
  • 25
    • 0024597579 scopus 로고
    • Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse
    • Wilkinson DG, Bhatt S, Chavrier P, Bravo R, Charnay P, (1989) Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse. Nature 337: 461-464.
    • (1989) Nature , vol.337 , pp. 461-464
    • Wilkinson, D.G.1    Bhatt, S.2    Chavrier, P.3    Bravo, R.4    Charnay, P.5
  • 26
    • 0024430616 scopus 로고
    • Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain
    • Wilkinson DG, Bhatt S, Cook M, Boncinelli E, Krumlauf R, (1989) Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain. Nature 341: 405-409.
    • (1989) Nature , vol.341 , pp. 405-409
    • Wilkinson, D.G.1    Bhatt, S.2    Cook, M.3    Boncinelli, E.4    Krumlauf, R.5
  • 27
    • 0032527879 scopus 로고    scopus 로고
    • Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury
    • Herdegen T, Claret FX, Kallunki T, Martin-Villalba A, Winter C, et al. (1998) Lasting N-terminal phosphorylation of c-Jun and activation of c-Jun N-terminal kinases after neuronal injury. J Neurosci 18: 5124-5135.
    • (1998) J Neurosci , vol.18 , pp. 5124-5135
    • Herdegen, T.1    Claret, F.X.2    Kallunki, T.3    Martin-Villalba, A.4    Winter, C.5
  • 28
    • 0031149046 scopus 로고    scopus 로고
    • The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration
    • Herdegen T, Skene P, Bahr M, (1997) The c-Jun transcription factor-bipotential mediator of neuronal death, survival and regeneration. Trends Neurosci 20: 227-231.
    • (1997) Trends Neurosci , vol.20 , pp. 227-231
    • Herdegen, T.1    Skene, P.2    Bahr, M.3
  • 29
    • 4744355139 scopus 로고    scopus 로고
    • c-Jun N-terminal kinases (JNKs) and the cytoskeleton-functions beyond neurodegeneration
    • Gelderblom M, Eminel S, Herdegen T, Waetzig V, (2004) c-Jun N-terminal kinases (JNKs) and the cytoskeleton-functions beyond neurodegeneration. Int J Dev Neurosci 22: 559-564.
    • (2004) Int J Dev Neurosci , vol.22 , pp. 559-564
    • Gelderblom, M.1    Eminel, S.2    Herdegen, T.3    Waetzig, V.4
  • 30
    • 11844296011 scopus 로고    scopus 로고
    • Mutations of brainstem transcription factors and central respiratory disorders
    • Blanchi B, Sieweke MH, (2005) Mutations of brainstem transcription factors and central respiratory disorders. Trends Mol Med 11: 23-30.
    • (2005) Trends Mol Med , vol.11 , pp. 23-30
    • Blanchi, B.1    Sieweke, M.H.2
  • 32
    • 0345181834 scopus 로고    scopus 로고
    • Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways
    • Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, et al. (2003) Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development 130: 6635-6642.
    • (2003) Development , vol.130 , pp. 6635-6642
    • Dauger, S.1    Pattyn, A.2    Lofaso, F.3    Gaultier, C.4    Goridis, C.5
  • 33
    • 0141765815 scopus 로고    scopus 로고
    • MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth
    • Blanchi B, Kelly LM, Viemari JC, Lafon I, Burnet H, et al. (2003) MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth. Nat Neurosci 6: 1091-1100.
    • (2003) Nat Neurosci , vol.6 , pp. 1091-1100
    • Blanchi, B.1    Kelly, L.M.2    Viemari, J.C.3    Lafon, I.4    Burnet, H.5
  • 34
    • 0028984595 scopus 로고
    • Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters
    • Bianchi AL, Denavit-Saubie M, Champagnat J, (1995) Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmitters. Physiol Rev 75: 1-45.
    • (1995) Physiol Rev , vol.75 , pp. 1-45
    • Bianchi, A.L.1    Denavit-Saubie, M.2    Champagnat, J.3
  • 35
    • 63949083096 scopus 로고    scopus 로고
    • Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopment
    • Ottaviani G, Mingrone R, Lavezzi AM, Matturri L, (2009) Infant and perinatal pulmonary hypoplasia frequently associated with brainstem hypodevelopment. Virchows Arch 454: 451-456.
    • (2009) Virchows Arch , vol.454 , pp. 451-456
    • Ottaviani, G.1    Mingrone, R.2    Lavezzi, A.M.3    Matturri, L.4
  • 36
    • 33646422997 scopus 로고    scopus 로고
    • Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant death
    • Ottaviani G, Matturri L, Mingrone R, Lavezzi AM, (2006) Hypoplasia and neuronal immaturity of the hypoglossal nucleus in sudden infant death. J Clin Pathol 59: 497-500.
    • (2006) J Clin Pathol , vol.59 , pp. 497-500
    • Ottaviani, G.1    Matturri, L.2    Mingrone, R.3    Lavezzi, A.M.4
  • 37
    • 0034303585 scopus 로고    scopus 로고
    • Neuronal specification in the spinal cord: inductive signals and transcriptional codes
    • Jessell TM, (2000) Neuronal specification in the spinal cord: inductive signals and transcriptional codes. Nat Rev Genet 1: 20-29.
    • (2000) Nat Rev Genet , vol.1 , pp. 20-29
    • Jessell, T.M.1
  • 38
    • 0031900077 scopus 로고    scopus 로고
    • Neuronal diversification: development of motor neuron subtypes
    • Pfaff S, Kintner C, (1998) Neuronal diversification: development of motor neuron subtypes. Curr Opin Neurobiol 8: 27-36.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 27-36
    • Pfaff, S.1    Kintner, C.2
  • 39
    • 0033179908 scopus 로고    scopus 로고
    • Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9
    • Thaler J, Harrison K, Sharma K, Lettieri K, Kehrl J, et al. (1999) Active suppression of interneuron programs within developing motor neurons revealed by analysis of homeodomain factor HB9. Neuron 23: 675-687.
    • (1999) Neuron , vol.23 , pp. 675-687
    • Thaler, J.1    Harrison, K.2    Sharma, K.3    Lettieri, K.4    Kehrl, J.5
  • 40
    • 0033180516 scopus 로고    scopus 로고
    • Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity
    • Arber S, Han B, Mendelsohn M, Smith M, Jessell TM, et al. (1999) Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron 23: 659-674.
    • (1999) Neuron , vol.23 , pp. 659-674
    • Arber, S.1    Han, B.2    Mendelsohn, M.3    Smith, M.4    Jessell, T.M.5
  • 41
    • 1242316153 scopus 로고    scopus 로고
    • A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity
    • Thaler JP, Koo SJ, Kania A, Lettieri K, Andrews S, et al. (2004) A postmitotic role for Isl-class LIM homeodomain proteins in the assignment of visceral spinal motor neuron identity. Neuron 41: 337-350.
    • (2004) Neuron , vol.41 , pp. 337-350
    • Thaler, J.P.1    Koo, S.J.2    Kania, A.3    Lettieri, K.4    Andrews, S.5
  • 42
    • 0242550675 scopus 로고    scopus 로고
    • Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons
    • Gaufo GO, Thomas KR, Capecchi MR, (2003) Hox3 genes coordinate mechanisms of genetic suppression and activation in the generation of branchial and somatic motoneurons. Development 130: 5191-5201.
    • (2003) Development , vol.130 , pp. 5191-5201
    • Gaufo, G.O.1    Thomas, K.R.2    Capecchi, M.R.3
  • 43
    • 0035697007 scopus 로고    scopus 로고
    • Hindbrain patterning: Krox20 couples segmentation and specification of regional identity
    • Voiculescu O, Taillebourg E, Pujades C, Kress C, Buart S, et al. (2001) Hindbrain patterning: Krox20 couples segmentation and specification of regional identity. Development 128: 4967-4978.
    • (2001) Development , vol.128 , pp. 4967-4978
    • Voiculescu, O.1    Taillebourg, E.2    Pujades, C.3    Kress, C.4    Buart, S.5
  • 44
    • 0031573959 scopus 로고    scopus 로고
    • Hox Group 3 Paralogous Genes Act Synergistically in the Formation of Somitic and Neural Crest-Derived Structures
    • Manley NR, Capecchi MR, (1997) Hox Group 3 Paralogous Genes Act Synergistically in the Formation of Somitic and Neural Crest-Derived Structures. Dev Biol 193: 274-288.
    • (1997) Dev Biol , vol.193 , pp. 274-288
    • Manley, N.R.1    Capecchi, M.R.2
  • 46
    • 20444400796 scopus 로고    scopus 로고
    • Phosphorylation of c-Jun in avian and mammalian motoneurons in vivo during programmed cell death: an early reversible event in the apoptotic cascade
    • Sun W, Gould TW, Newbern J, Milligan C, Choi SY, et al. (2005) Phosphorylation of c-Jun in avian and mammalian motoneurons in vivo during programmed cell death: an early reversible event in the apoptotic cascade. J Neurosci 25: 5595-5603.
    • (2005) J Neurosci , vol.25 , pp. 5595-5603
    • Sun, W.1    Gould, T.W.2    Newbern, J.3    Milligan, C.4    Choi, S.Y.5
  • 47
    • 0032979438 scopus 로고    scopus 로고
    • Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation
    • Behrens A, Sibilia M, Wagner EF, (1999) Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation. Nat Genet 21: 326-329.
    • (1999) Nat Genet , vol.21 , pp. 326-329
    • Behrens, A.1    Sibilia, M.2    Wagner, E.F.3
  • 48
    • 15644381250 scopus 로고    scopus 로고
    • Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1
    • Maundrell K, Antonsson B, Magnenat E, Camps M, Muda M, et al. (1997) Bcl-2 undergoes phosphorylation by c-Jun N-terminal kinase/stress-activated protein kinases in the presence of the constitutively active GTP-binding protein Rac1. J Biol Chem 272: 25238-25242.
    • (1997) J Biol Chem , vol.272 , pp. 25238-25242
    • Maundrell, K.1    Antonsson, B.2    Magnenat, E.3    Camps, M.4    Muda, M.5
  • 49
    • 0033499801 scopus 로고    scopus 로고
    • BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M
    • Yamamoto K, Ichijo H, Korsmeyer SJ, (1999) BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M. Mol Cell Biol 19: 8469-8478.
    • (1999) Mol Cell Biol , vol.19 , pp. 8469-8478
    • Yamamoto, K.1    Ichijo, H.2    Korsmeyer, S.J.3
  • 50
    • 0034614658 scopus 로고    scopus 로고
    • Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage
    • Kharbanda S, Saxena S, Yoshida K, Pandey P, Kaneki M, et al. (2000) Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage. J Biol Chem 275: 322-327.
    • (2000) J Biol Chem , vol.275 , pp. 322-327
    • Kharbanda, S.1    Saxena, S.2    Yoshida, K.3    Pandey, P.4    Kaneki, M.5
  • 51
    • 0037418238 scopus 로고    scopus 로고
    • JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
    • Lei K, Davis RJ, (2003) JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis. Proc Natl Acad Sci U S A 100: 2432-2437.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2432-2437
    • Lei, K.1    Davis, R.J.2
  • 52
    • 0033994852 scopus 로고    scopus 로고
    • Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3
    • Brownlees J, Yates A, Bajaj NP, Davis D, Anderton BH, et al. (2000) Phosphorylation of neurofilament heavy chain side-arms by stress activated protein kinase-1b/Jun N-terminal kinase-3. J Cell Sci 113 401-407.
    • (2000) J Cell Sci , vol.113 , pp. 401-407
    • Brownlees, J.1    Yates, A.2    Bajaj, N.P.3    Davis, D.4    Anderton, B.H.5
  • 53
    • 33644931106 scopus 로고    scopus 로고
    • Role of extracellular-regulated kinase and c-Jun NH2-terminal kinase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurofilament phosphorylation
    • De Girolamo LA, Billett EE, (2006) Role of extracellular-regulated kinase and c-Jun NH2-terminal kinase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurofilament phosphorylation. J Neurosci Res 83: 680-693.
    • (2006) J Neurosci Res , vol.83 , pp. 680-693
    • De Girolamo, L.A.1    Billett, E.E.2
  • 54
    • 4644362726 scopus 로고    scopus 로고
    • p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis
    • Ackerley S, Grierson AJ, Banner S, Perkinton MS, Brownlees J, et al. (2004) p38alpha stress-activated protein kinase phosphorylates neurofilaments and is associated with neurofilament pathology in amyotrophic lateral sclerosis. Mol Cell Neurosci 26: 354-364.
    • (2004) Mol Cell Neurosci , vol.26 , pp. 354-364
    • Ackerley, S.1    Grierson, A.J.2    Banner, S.3    Perkinton, M.S.4    Brownlees, J.5
  • 55
    • 19444374567 scopus 로고    scopus 로고
    • Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice
    • Holasek SS, Wengenack TM, Kandimalla KK, Montano C, Gregor DM, et al. (2005) Activation of the stress-activated MAP kinase, p38, but not JNK in cortical motor neurons during early presymptomatic stages of amyotrophic lateral sclerosis in transgenic mice. Brain Res 1045: 185-198.
    • (2005) Brain Res , vol.1045 , pp. 185-198
    • Holasek, S.S.1    Wengenack, T.M.2    Kandimalla, K.K.3    Montano, C.4    Gregor, D.M.5
  • 56
    • 0037068836 scopus 로고    scopus 로고
    • Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations
    • Raoul C, Estevez AG, Nishimune H, Cleveland DW, deLapeyriere O, et al. (2002) Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron 35: 1067-1083.
    • (2002) Neuron , vol.35 , pp. 1067-1083
    • Raoul, C.1    Estevez, A.G.2    Nishimune, H.3    Cleveland, D.W.4    de Lapeyriere, O.5
  • 57
    • 34147131311 scopus 로고    scopus 로고
    • Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death
    • Dewil M, dela Cruz VF, Van Den Bosch L, Robberecht W, (2007) Inhibition of p38 mitogen activated protein kinase activation and mutant SOD1(G93A)-induced motor neuron death. Neurobiol Dis 26: 332-341.
    • (2007) Neurobiol Dis , vol.26 , pp. 332-341
    • Dewil, M.1    dela Cruz, V.F.2    van Den Bosch, L.3    Robberecht, W.4
  • 58
    • 36949019768 scopus 로고    scopus 로고
    • Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences
    • Kato S, (2008) Amyotrophic lateral sclerosis models and human neuropathology: similarities and differences. Acta Neuropathol 115: 97-114.
    • (2008) Acta Neuropathol , vol.115 , pp. 97-114
    • Kato, S.1
  • 59
    • 0035955478 scopus 로고    scopus 로고
    • Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients
    • Shibata N, Nagai R, Uchida K, Horiuchi S, Yamada S, et al. (2001) Morphological evidence for lipid peroxidation and protein glycoxidation in spinal cords from sporadic amyotrophic lateral sclerosis patients. Brain Res 917: 97-104.
    • (2001) Brain Res , vol.917 , pp. 97-104
    • Shibata, N.1    Nagai, R.2    Uchida, K.3    Horiuchi, S.4    Yamada, S.5
  • 60
    • 32244441514 scopus 로고    scopus 로고
    • Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS
    • Veglianese P, Lo Coco D, Bao Cutrona M, Magnoni R, Pennacchini D, et al. (2006) Activation of the p38MAPK cascade is associated with upregulation of TNF alpha receptors in the spinal motor neurons of mouse models of familial ALS. Mol Cell Neurosci 31: 218-231.
    • (2006) Mol Cell Neurosci , vol.31 , pp. 218-231
    • Veglianese, P.1    Lo Coco, D.2    Bao Cutrona, M.3    Magnoni, R.4    Pennacchini, D.5
  • 61
    • 0035478618 scopus 로고    scopus 로고
    • Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand
    • Morishima Y, Gotoh Y, Zieg J, Barrett T, Takano H, et al. (2001) Beta-amyloid induces neuronal apoptosis via a mechanism that involves the c-Jun N-terminal kinase pathway and the induction of Fas ligand. J Neurosci 21: 7551-7560.
    • (2001) J Neurosci , vol.21 , pp. 7551-7560
    • Morishima, Y.1    Gotoh, Y.2    Zieg, J.3    Barrett, T.4    Takano, H.5
  • 62
    • 0346374790 scopus 로고    scopus 로고
    • JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease
    • Hunot S, Vila M, Teismann P, Davis RJ, Hirsch EC, et al. (2004) JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proc Natl Acad Sci U S A 101: 665-670.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 665-670
    • Hunot, S.1    Vila, M.2    Teismann, P.3    Davis, R.J.4    Hirsch, E.C.5
  • 63
    • 0035140889 scopus 로고    scopus 로고
    • Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice
    • Reimold AM, Kim J, Finberg R, Glimcher LH, (2001) Decreased immediate inflammatory gene induction in activating transcription factor-2 mutant mice. Int Immunol 13: 241-248.
    • (2001) Int Immunol , vol.13 , pp. 241-248
    • Reimold, A.M.1    Kim, J.2    Finberg, R.3    Glimcher, L.H.4
  • 64
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle RD, Johnson RL, Laufer E, Tabin C, (1993) Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75: 1401-1416.
    • (1993) Cell , vol.75 , pp. 1401-1416
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 66
    • 0003111719 scopus 로고
    • Lipids
    • In: Bancroft JD, Stevens A, editors, New York, Churchill Livingstone
    • Bayliss High OB, (1990) Lipids. In: Bancroft JD, Stevens A, editors. Theory and Practice of Histological Techniques New York Churchill Livingstone pp. 215-244.
    • (1990) Theory and Practice of Histological Techniques , pp. 215-244
    • Bayliss High, O.B.1
  • 67
    • 0003446246 scopus 로고
    • Biological electron microscopy: Theory, techniques, and troubleshooting
    • New York, Plenum Press
    • Dykstra MJ, (1992) Biological electron microscopy: Theory, techniques, and troubleshooting. xvii New York Plenum Press.
    • (1992) , vol.xvii
    • Dykstra, M.J.1
  • 68
    • 0034734126 scopus 로고    scopus 로고
    • Postnatal development of 5-HT(1A) receptor expression in rat somatic motoneurons
    • Talley EM, Bayliss DA, (2000) Postnatal development of 5-HT(1A) receptor expression in rat somatic motoneurons. Brain Res Dev Brain Res 122: 1-10.
    • (2000) Brain Res Dev Brain Res , vol.122 , pp. 1-10
    • Talley, E.M.1    Bayliss, D.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.