Bordetella pertussis infection exacerbates influenza virus infection through pertussis toxin-mediated suppression of innate immunity

PLoS ONE

Volumn 6, Issue 4, 2011, Pages

  Ayala, Victor I ^a   Teijaro, John R ^a,b   Farber, Donna L ^a,c   Dorsey, Susan G ^d   Carbonetti, Nicholas H ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

^c The Scripps Research Institute ^*  (United States)

^d UNIVERSITY OF MARYLAND SCHOOL OF NURSING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CXCL1 CHEMOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; PERTUSSIS TOXIN; RANTES; RGS PROTEIN; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE;

ADAPTIVE IMMUNITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE EXACERBATION; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENETIC ASSOCIATION; IMMUNE DEFICIENCY; IMMUNE RESPONSE; INFLUENZA; INFLUENZA VIRUS; INNATE IMMUNITY; LUNG ALVEOLUS MACROPHAGE; MICROARRAY ANALYSIS; MOUSE; NATURAL KILLER CELL; NEUTROPHIL; NONHUMAN; PATHOGEN LOAD; PERTUSSIS; SURVIVAL RATE; TRACHEA MUCOSA; VIRUS CELL INTERACTION; VIRUS REPLICATION; VIRUS TITRATION; WEIGHT CHANGE; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DNA MICROARRAY; DRUG EFFECT; IMMUNOLOGY; LUNG; METABOLISM; ORTHOMYXOVIRUS INFECTION; PATHOPHYSIOLOGY;

BORDETELLA PERTUSSIS; MURINAE; MUS; ORTHOMYXOVIRIDAE;

ANIMALS; CYTOKINES; GENE EXPRESSION; IMMUNITY, INNATE; LUNG; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORTHOMYXOVIRIDAE INFECTIONS; PERTUSSIS TOXIN; VIRUS REPLICATION; WHOOPING COUGH;

EID: 79955420834     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0019016     Document Type: Article

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