-
1
-
-
0032541671
-
Cell cycle targets of Ras/Raf signalling
-
Kerkhoff E., Rapp U.R. Cell cycle targets of Ras/Raf signalling. Oncogene 1998, 17:1457-1462.
-
(1998)
Oncogene
, vol.17
, pp. 1457-1462
-
-
Kerkhoff, E.1
Rapp, U.R.2
-
2
-
-
0030740210
-
Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts
-
Takuwa N., Takuwa Y. Ras activity late in G1 phase required for p27kip1 downregulation, passage through the restriction point and entry into S phase in growth factor-stimulated NIH 3T3 fibroblasts. Mol. Cell Biol. 1997, 17:5348-5358.
-
(1997)
Mol. Cell Biol.
, vol.17
, pp. 5348-5358
-
-
Takuwa, N.1
Takuwa, Y.2
-
3
-
-
0029831907
-
Regulation of reactive-oxygen-species generation in fibroblasts by Rac1
-
Sundaresan M., Yu Z.X., Ferrans V.J., Sulciner D.J., Gutkind J.S., Irani K., Goldschmidt-Clermont P.J., Finkel T. Regulation of reactive-oxygen-species generation in fibroblasts by Rac1. Biochem. J. 1996, 318(Pt 2):379-382.
-
(1996)
Biochem. J.
, vol.318
, Issue.PART 2
, pp. 379-382
-
-
Sundaresan, M.1
Yu, Z.X.2
Ferrans, V.J.3
Sulciner, D.J.4
Gutkind, J.S.5
Irani, K.6
Goldschmidt-Clermont, P.J.7
Finkel, T.8
-
4
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani K., Xia Y., Zweier J.L., Sollott S.J., Der C.J., Fearon E.R., Sundaresan M., Finkel T., Goldschmidt-Clermont P.J. Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 1997, 275:1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
5
-
-
0033583242
-
Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species
-
Lee A.C., Fenster B.E., Ito H., Takeda K., Bae N.S., Hirai T., Yu Z.X., Ferrans V.J., Howard B.H., Finkel T. Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species. J. Biol. Chem. 1999, 274:7936-7940.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 7936-7940
-
-
Lee, A.C.1
Fenster, B.E.2
Ito, H.3
Takeda, K.4
Bae, N.S.5
Hirai, T.6
Yu, Z.X.7
Ferrans, V.J.8
Howard, B.H.9
Finkel, T.10
-
6
-
-
0032732639
-
Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells
-
Yang J.Q., Li S., Domann F.E., Buettner G.R., Oberley L.W. Superoxide generation in v-Ha-ras-transduced human keratinocyte HaCaT cells. Mol. Carcinog. 1999, 26:180-188.
-
(1999)
Mol. Carcinog.
, vol.26
, pp. 180-188
-
-
Yang, J.Q.1
Li, S.2
Domann, F.E.3
Buettner, G.R.4
Oberley, L.W.5
-
7
-
-
0034671502
-
Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species
-
Liou J.S., Chen C.Y., Chen J.S., Faller D.V. Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species. J. Biol. Chem. 2000, 275:39001-39011.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39001-39011
-
-
Liou, J.S.1
Chen, C.Y.2
Chen, J.S.3
Faller, D.V.4
-
8
-
-
8844230280
-
Mutant K-rasV12 increases COX-2, peroxides and DNA damage in lung cells
-
Maciag A., Sithanandam G., Anderson L.M. Mutant K-rasV12 increases COX-2, peroxides and DNA damage in lung cells. Carcinogenesis 2004, 25:2231-2237.
-
(2004)
Carcinogenesis
, vol.25
, pp. 2231-2237
-
-
Maciag, A.1
Sithanandam, G.2
Anderson, L.M.3
-
9
-
-
34548543291
-
DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells
-
Romanowska M., Maciag A., Smith A.L., Fields J.R., Fornwald L.W., Kikawa K.D., Kasprzak K.S., Anderson L.M., damage DNA DNA damage, superoxide, and mutant K-ras in human lung adenocarcinoma cells. Free Radic. Biol. Med. 2007, 43:1145-1155.
-
(2007)
Free Radic. Biol. Med.
, vol.43
, pp. 1145-1155
-
-
Romanowska, M.1
Maciag, A.2
Smith, A.L.3
Fields, J.R.4
Fornwald, L.W.5
Kikawa, K.D.6
Kasprzak, K.S.7
Anderson, L.M.8
damage, D.N.A.9
-
10
-
-
0033918563
-
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3
-
Dammann R., Li C., Yoon J.H., Chin P.L., Bates S., Pfeifer G.P. Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3. Nat. Genet. 2000, 25:315-319.
-
(2000)
Nat. Genet.
, vol.25
, pp. 315-319
-
-
Dammann, R.1
Li, C.2
Yoon, J.H.3
Chin, P.L.4
Bates, S.5
Pfeifer, G.P.6
-
11
-
-
0035795676
-
Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression
-
Burbee D.G., Forgacs E., Zochbauer-Muller S., Shivakumar L., Fong K., Gao B., Randle D., Kondo M., Virmani A., Bader S., Sekido Y., Latif F., Milchgrub S., Toyooka S., Gazdar A.F., Lerman M.I., Zabarovsky E., White M., Minna J.D. Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression. J. Natl. Cancer Inst. 2001, 93:691-699.
-
(2001)
J. Natl. Cancer Inst.
, vol.93
, pp. 691-699
-
-
Burbee, D.G.1
Forgacs, E.2
Zochbauer-Muller, S.3
Shivakumar, L.4
Fong, K.5
Gao, B.6
Randle, D.7
Kondo, M.8
Virmani, A.9
Bader, S.10
Sekido, Y.11
Latif, F.12
Milchgrub, S.13
Toyooka, S.14
Gazdar, A.F.15
Lerman, M.I.16
Zabarovsky, E.17
White, M.18
Minna, J.D.19
-
12
-
-
18144411303
-
Role of the Ras-association domain family 1 tumor suppressor gene in human cancers
-
Agathanggelou A., Cooper W.N., Latif F. Role of the Ras-association domain family 1 tumor suppressor gene in human cancers. Cancer Res. 2005, 65:3497-3508.
-
(2005)
Cancer Res.
, vol.65
, pp. 3497-3508
-
-
Agathanggelou, A.1
Cooper, W.N.2
Latif, F.3
-
13
-
-
19944429131
-
Tumor susceptibility of Rassf1a knockout mice
-
Tommasi S., Dammann R., Zhang Z., Wang Y., Liu L., Tsark W.M., Wilczynski S.P., Li J., You M., Pfeifer G.P. Tumor susceptibility of Rassf1a knockout mice. Cancer Res. 2005, 65:92-98.
-
(2005)
Cancer Res.
, vol.65
, pp. 92-98
-
-
Tommasi, S.1
Dammann, R.2
Zhang, Z.3
Wang, Y.4
Liu, L.5
Tsark, W.M.6
Wilczynski, S.P.7
Li, J.8
You, M.9
Pfeifer, G.P.10
-
14
-
-
0036264815
-
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation
-
Shivakumar L., Minna J., Sakamaki T., Pestell R., White M.A. The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation. Mol. Cell Biol. 2002, 22:4309-4318.
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 4309-4318
-
-
Shivakumar, L.1
Minna, J.2
Sakamaki, T.3
Pestell, R.4
White, M.A.5
-
15
-
-
18144380299
-
RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression
-
Whang Y.M., Kim Y.H., Kim J.S., Yoo Y.D. RASSF1A suppresses the c-Jun-NH2-kinase pathway and inhibits cell cycle progression. Cancer Res. 2005, 65:3682-3690.
-
(2005)
Cancer Res.
, vol.65
, pp. 3682-3690
-
-
Whang, Y.M.1
Kim, Y.H.2
Kim, J.S.3
Yoo, Y.D.4
-
16
-
-
39049184873
-
RASSF1A suppresses oncogenic H-Ras-induced c-Jun N-terminal kinase activation
-
Yoo Y.A., Na A.R., Lee M.S., Yoon S., Kim J.S., Yoo Y.D. RASSF1A suppresses oncogenic H-Ras-induced c-Jun N-terminal kinase activation. Int. J. Oncol. 2006, 29:1541-1547.
-
(2006)
Int. J. Oncol.
, vol.29
, pp. 1541-1547
-
-
Yoo, Y.A.1
Na, A.R.2
Lee, M.S.3
Yoon, S.4
Kim, J.S.5
Yoo, Y.D.6
-
17
-
-
33646194020
-
The RASSF1A tumor suppressor activates Bax via MOAP-1
-
Vos M.D., Dallol A., Eckfeld K., Allen N.P., Donninger H., Hesson L.B., Calvisi D., Latif F., Clark G.J. The RASSF1A tumor suppressor activates Bax via MOAP-1. J. Biol. Chem. 2006, 281:4557-4563.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 4557-4563
-
-
Vos, M.D.1
Dallol, A.2
Eckfeld, K.3
Allen, N.P.4
Donninger, H.5
Hesson, L.B.6
Calvisi, D.7
Latif, F.8
Clark, G.J.9
-
19
-
-
70349174971
-
The RASSF proteins in cancer; from epigenetic silencing to functional characterization
-
Richter A.M., Pfeifer G.P., Dammann R.H. The RASSF proteins in cancer; from epigenetic silencing to functional characterization. Biochim. Biophys. Acta 2009, 1796:114-128.
-
(2009)
Biochim. Biophys. Acta
, vol.1796
, pp. 114-128
-
-
Richter, A.M.1
Pfeifer, G.P.2
Dammann, R.H.3
-
20
-
-
33746329589
-
A novel protein, Romo1. Induces ROS production in the mitochondria
-
Chung Y.M., Kim J.S., Yoo Y.D. A novel protein, Romo1. Induces ROS production in the mitochondria. Biochem. Biophys. Res. Commun. 2006, 347:649-655.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.347
, pp. 649-655
-
-
Chung, Y.M.1
Kim, J.S.2
Yoo, Y.D.3
-
21
-
-
77955713258
-
TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L)
-
Kim J.J., Lee S.B., Park J.K., Yoo Y.D. TNF-alpha-induced ROS production triggering apoptosis is directly linked to Romo1 and Bcl-X(L). Cell Death Differ. 2010, 17:1420-1434.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 1420-1434
-
-
Kim, J.J.1
Lee, S.B.2
Park, J.K.3
Yoo, Y.D.4
-
22
-
-
77949264281
-
Serum deprivation-induced reactive oxygen species production is mediated by Romo1
-
Lee S.B., Kim J.J., Kim T.W., Kim B.S., Lee M.S., Yoo Y.D. Serum deprivation-induced reactive oxygen species production is mediated by Romo1. Apoptosis 2010, 15:204-218.
-
(2010)
Apoptosis
, vol.15
, pp. 204-218
-
-
Lee, S.B.1
Kim, J.J.2
Kim, T.W.3
Kim, B.S.4
Lee, M.S.5
Yoo, Y.D.6
-
23
-
-
0034693730
-
The in vitro micronucleus technique
-
Fenech M. The in vitro micronucleus technique. Mutat. Res. 2000, 455:81-95.
-
(2000)
Mutat. Res.
, vol.455
, pp. 81-95
-
-
Fenech, M.1
-
24
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S.Y., Ikeda M., Taya Y., Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997, 91:325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
25
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
Burma S., Chen B.P., Murphy M., Kurimasa A., Chen D.J. ATM phosphorylates histone H2AX in response to DNA double-strand breaks. J. Biol. Chem. 2001, 276:42462-42467.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
26
-
-
34249026448
-
Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice
-
Gupta S., Ramjaun A.R., Haiko P., Wang Y., Warne P.H., Nicke B., Nye E., Stamp G., Alitalo K., Downward J. Binding of ras to phosphoinositide 3-kinase p110alpha is required for ras-driven tumorigenesis in mice. Cell 2007, 129:957-968.
-
(2007)
Cell
, vol.129
, pp. 957-968
-
-
Gupta, S.1
Ramjaun, A.R.2
Haiko, P.3
Wang, Y.4
Warne, P.H.5
Nicke, B.6
Nye, E.7
Stamp, G.8
Alitalo, K.9
Downward, J.10
-
28
-
-
79953856887
-
Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation
-
Kim M.J., Woo S.J., Yoon C.H., Lee J.S., An S., Choi Y.H., Hwang S.G., Yoon G., Lee S.J. Involvement of autophagy in oncogenic K-Ras-induced malignant cell transformation. J. Biol. Chem. 2011.
-
(2011)
J. Biol. Chem.
-
-
Kim, M.J.1
Woo, S.J.2
Yoon, C.H.3
Lee, J.S.4
An, S.5
Choi, Y.H.6
Hwang, S.G.7
Yoon, G.8
Lee, S.J.9
-
29
-
-
0036219617
-
V-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species
-
Yang J.Q., Buettner G.R., Domann F.E., Li Q., Engelhardt J.F., Weydert C.D., Oberley L.W. v-Ha-ras mitogenic signaling through superoxide and derived reactive oxygen species. Mol. Carcinog. 2002, 33:206-218.
-
(2002)
Mol. Carcinog.
, vol.33
, pp. 206-218
-
-
Yang, J.Q.1
Buettner, G.R.2
Domann, F.E.3
Li, Q.4
Engelhardt, J.F.5
Weydert, C.D.6
Oberley, L.W.7
-
30
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge W. Free radicals in the physiological control of cell function. Physiol. Rev. 2002, 82:47-95.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 47-95
-
-
Droge, W.1
|