-
1
-
-
33748534122
-
Effect of Conantokin G on NMDA receptor-mediated spontaneous EPSCs in cultured cortical neurons
-
Alex A.B., Baucum A.J., Wilcox K.S. Effect of Conantokin G on NMDA receptor-mediated spontaneous EPSCs in cultured cortical neurons. J Neurophysiol 2006, 96(3):1084-1092.
-
(2006)
J Neurophysiol
, vol.96
, Issue.3
, pp. 1084-1092
-
-
Alex, A.B.1
Baucum, A.J.2
Wilcox, K.S.3
-
2
-
-
0002780023
-
Anticonvulsant profile of Conantokin-G: a novel, broad spectrum NMDA antagonist
-
Armstrong H., Zhou L., Layer R., Nielson J., McCabe R.T., White H.S. Anticonvulsant profile of Conantokin-G: a novel, broad spectrum NMDA antagonist. Epilpesia 1998, 36:39.
-
(1998)
Epilpesia
, vol.36
, pp. 39
-
-
Armstrong, H.1
Zhou, L.2
Layer, R.3
Nielson, J.4
McCabe, R.T.5
White, H.S.6
-
3
-
-
2342649960
-
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs
-
Barton M.E., White H.S., Wilcox K.S. The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on NMDA receptor-mediated EPSCs. Epilepsy Res 2004, 59(1):13-24.
-
(2004)
Epilepsy Res
, vol.59
, Issue.1
, pp. 13-24
-
-
Barton, M.E.1
White, H.S.2
Wilcox, K.S.3
-
4
-
-
2342654311
-
The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on kindling acquisition and expression
-
Barton M.E., White H.S. The effect of CGX-1007 and CI-1041, novel NMDA receptor antagonists, on kindling acquisition and expression. Epilepsy Res 2004, 59(1):1-12.
-
(2004)
Epilepsy Res
, vol.59
, Issue.1
, pp. 1-12
-
-
Barton, M.E.1
White, H.S.2
-
5
-
-
0023392945
-
High-efficiency transformation of mammalian cells by plasmid DNA
-
Chen C., Okayama H. High-efficiency transformation of mammalian cells by plasmid DNA. Mol Cell Biol 1987, 7(8):2745-2752.
-
(1987)
Mol Cell Biol
, vol.7
, Issue.8
, pp. 2745-2752
-
-
Chen, C.1
Okayama, H.2
-
6
-
-
0025265926
-
The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death
-
Choi D.W., Rothman S.M. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annu Rev Neurosci 1990, 13:171-182.
-
(1990)
Annu Rev Neurosci
, vol.13
, pp. 171-182
-
-
Choi, D.W.1
Rothman, S.M.2
-
7
-
-
0032912771
-
The glutamate receptor ion channels
-
Dingledine R., Borges K., Bowie D., Traynelis S.F. The glutamate receptor ion channels. Pharmacol Rev 1999, 51(1):7-61.
-
(1999)
Pharmacol Rev
, vol.51
, Issue.1
, pp. 7-61
-
-
Dingledine, R.1
Borges, K.2
Bowie, D.3
Traynelis, S.F.4
-
8
-
-
0033851790
-
Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors
-
Donevan S.D., McCabe R.T. Conantokin G is an NR2B-selective competitive antagonist of N-methyl-D-aspartate receptors. Mol Pharmacol 2000, 58(3):614-623.
-
(2000)
Mol Pharmacol
, vol.58
, Issue.3
, pp. 614-623
-
-
Donevan, S.D.1
McCabe, R.T.2
-
9
-
-
56749185869
-
Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor
-
Han X., Tomitori H., Mizuno S., Higashi K., Full C., Fukiwake T., et al. Binding of spermine and ifenprodil to a purified, soluble regulatory domain of the N-methyl-D-aspartate receptor. J Neurochem 2008, 107(6):1566-1577.
-
(2008)
J Neurochem
, vol.107
, Issue.6
, pp. 1566-1577
-
-
Han, X.1
Tomitori, H.2
Mizuno, S.3
Higashi, K.4
Full, C.5
Fukiwake, T.6
-
10
-
-
77956917231
-
Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders
-
Hardingham G.E., Bading H. Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders. Nat Rev Neurosci 2010, 11(10):682-696.
-
(2010)
Nat Rev Neurosci
, vol.11
, Issue.10
, pp. 682-696
-
-
Hardingham, G.E.1
Bading, H.2
-
11
-
-
0036241207
-
Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways
-
Hardingham G.E., Fukunaga Y., Bading H. Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways. Nat Neurosci 2002, 5(5):405-414.
-
(2002)
Nat Neurosci
, vol.5
, Issue.5
, pp. 405-414
-
-
Hardingham, G.E.1
Fukunaga, Y.2
Bading, H.3
-
12
-
-
17444426068
-
Modulation of triheteromeric NMDA receptors by N-terminal domain ligands
-
Hatton C.J., Paoletti P. Modulation of triheteromeric NMDA receptors by N-terminal domain ligands. Neuron 2005, 46(2):261-274.
-
(2005)
Neuron
, vol.46
, Issue.2
, pp. 261-274
-
-
Hatton, C.J.1
Paoletti, P.2
-
13
-
-
0032104196
-
Characterization of desensitization in recombinant N-methyl-D-aspartate receptors: comparison with native receptors in cultured hippocampal neurons
-
Kendrick S.J., Dichter M.A., Wilcox K.S. Characterization of desensitization in recombinant N-methyl-D-aspartate receptors: comparison with native receptors in cultured hippocampal neurons. Brain Res Mol Brain Res 1998, 57(1):10-20.
-
(1998)
Brain Res Mol Brain Res
, vol.57
, Issue.1
, pp. 10-20
-
-
Kendrick, S.J.1
Dichter, M.A.2
Wilcox, K.S.3
-
14
-
-
0032521090
-
Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons
-
Kew J.N., Richards J.G., Mutel V., Kemp J.A. Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons. J Neurosci 1998, 18(6):1935-1943.
-
(1998)
J Neurosci
, vol.18
, Issue.6
, pp. 1935-1943
-
-
Kew, J.N.1
Richards, J.G.2
Mutel, V.3
Kemp, J.A.4
-
15
-
-
0035920125
-
The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors
-
Klein R.C., Prorok M., Galdzicki Z., Castellino F.J. The amino acid residue at sequence position 5 in the conantokin peptides partially governs subunit-selective antagonism of recombinant N-methyl-D-aspartate receptors. J Biol Chem 2001, 276(29):26860-26867.
-
(2001)
J Biol Chem
, vol.276
, Issue.29
, pp. 26860-26867
-
-
Klein, R.C.1
Prorok, M.2
Galdzicki, Z.3
Castellino, F.J.4
-
16
-
-
0032006313
-
N-terminal domains in the NR2 subunit control desensitization of NMDA receptors
-
Krupp J.J., Vissel B., Heinemann S.F., Westbrook G.L. N-terminal domains in the NR2 subunit control desensitization of NMDA receptors. Neuron 1998, 20(2):317-327.
-
(1998)
Neuron
, vol.20
, Issue.2
, pp. 317-327
-
-
Krupp, J.J.1
Vissel, B.2
Heinemann, S.F.3
Westbrook, G.L.4
-
17
-
-
33947331063
-
NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo
-
Liu Y., Wong T.P., Aarts M., Rooyakkers A., Liu L., Lai T.W., et al. NMDA receptor subunits have differential roles in mediating excitotoxic neuronal death both in vitro and in vivo. J Neurosci 2007, 27(11):2846-2857.
-
(2007)
J Neurosci
, vol.27
, Issue.11
, pp. 2846-2857
-
-
Liu, Y.1
Wong, T.P.2
Aarts, M.3
Rooyakkers, A.4
Liu, L.5
Lai, T.W.6
-
18
-
-
0031032658
-
The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B)
-
Luo J.W.Y., Yasuda R.P., Dunah A.W., Wolfe B.B. The majority of N-methyl-D-aspartate receptor complexes in adult rat cerebral cortex contain at least three different subunits (NR1/NR2A/NR2B). Mol Pharmacol 1997, 51(1):79-86.
-
(1997)
Mol Pharmacol
, vol.51
, Issue.1
, pp. 79-86
-
-
Luo, J.W.Y.1
Yasuda, R.P.2
Dunah, A.W.3
Wolfe, B.B.4
-
19
-
-
58149476292
-
In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death
-
Martel M.A., Wyllie D.J., Hardingham G.E. In developing hippocampal neurons, NR2B-containing N-methyl-D-aspartate receptors (NMDARs) can mediate signaling to neuronal survival and synaptic potentiation, as well as neuronal death. Neuroscience 2009, 158(1):334-343.
-
(2009)
Neuroscience
, vol.158
, Issue.1
, pp. 334-343
-
-
Martel, M.A.1
Wyllie, D.J.2
Hardingham, G.E.3
-
20
-
-
0032953691
-
Markers for neuronal degeneration in organotypic slice cultures
-
Noraberg J., Kristensen B.W., Zimmer J. Markers for neuronal degeneration in organotypic slice cultures. Brain Res Brain Res Protoc 1999, 3(3):278-290.
-
(1999)
Brain Res Brain Res Protoc
, vol.3
, Issue.3
, pp. 278-290
-
-
Noraberg, J.1
Kristensen, B.W.2
Zimmer, J.3
-
21
-
-
12344276497
-
Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies
-
Noraberg J. Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies. Altern Lab Anim 2004, 32(4):329-337.
-
(2004)
Altern Lab Anim
, vol.32
, Issue.4
, pp. 329-337
-
-
Noraberg, J.1
-
22
-
-
0036210933
-
Effects of the anticonvulsant retigabine on cultured cortical neurons: changes in electroresponsive properties and synaptic transmission
-
Otto J.F., Kimball M.M., Wilcox K.S. Effects of the anticonvulsant retigabine on cultured cortical neurons: changes in electroresponsive properties and synaptic transmission. Mol Pharmacol 2002, 61(4):921-927.
-
(2002)
Mol Pharmacol
, vol.61
, Issue.4
, pp. 921-927
-
-
Otto, J.F.1
Kimball, M.M.2
Wilcox, K.S.3
-
23
-
-
33644837888
-
NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G
-
Ragnarsson L., Yasuda T., Lewis R.J., Dodd P.R., Adams D.J. NMDA receptor subunit-dependent modulation by conantokin-G and Ala7-conantokin-G. J Neurochem 2006, 6(1):283-291.
-
(2006)
J Neurochem
, vol.6
, Issue.1
, pp. 283-291
-
-
Ragnarsson, L.1
Yasuda, T.2
Lewis, R.J.3
Dodd, P.R.4
Adams, D.J.5
-
24
-
-
0034551769
-
NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro
-
Sinor J.D., Du S., Venneti S., Blitzblau R.C., Leszkiewicz D.N., Rosenberg P.A., et al. NMDA and glutamate evoke excitotoxicity at distinct cellular locations in rat cortical neurons in vitro. J. Neurosci. 2000, 20(23):8831-8837.
-
(2000)
J. Neurosci.
, vol.20
, Issue.23
, pp. 8831-8837
-
-
Sinor, J.D.1
Du, S.2
Venneti, S.3
Blitzblau, R.C.4
Leszkiewicz, D.N.5
Rosenberg, P.A.6
-
25
-
-
55949137926
-
Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum
-
Smeal R.M., Keefe K.A., Wilcox K.S. Differences in excitatory transmission between thalamic and cortical afferents to single spiny efferent neurons of rat dorsal striatum. Eur J Neurosci 2008, 28(10):2041-2052.
-
(2008)
Eur J Neurosci
, vol.28
, Issue.10
, pp. 2041-2052
-
-
Smeal, R.M.1
Keefe, K.A.2
Wilcox, K.S.3
-
26
-
-
0032520117
-
Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons
-
Stocca G., Vicini S. Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons. J Physiol 1998, 507(Pt 1):13-24.
-
(1998)
J Physiol
, vol.507
, Issue.PART 1
, pp. 13-24
-
-
Stocca, G.1
Vicini, S.2
-
27
-
-
0025805120
-
A simple method for organotypic cultures of nervous tissue
-
Stoppini L., Buchs P.A., Muller D. A simple method for organotypic cultures of nervous tissue. J Neurosci Methods 1991, 37(2):173-182.
-
(1991)
J Neurosci Methods
, vol.37
, Issue.2
, pp. 173-182
-
-
Stoppini, L.1
Buchs, P.A.2
Muller, D.3
-
28
-
-
37549069739
-
Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors
-
Teichert R.W., Jimenez E.C., Twede V., Watkins M., Hollmann M., Bulaj G., et al. Novel conantokins from Conus parius venom are specific antagonists of N-methyl-D-aspartate receptors. J Biol Chem 2007, 282(51):36905-36913.
-
(2007)
J Biol Chem
, vol.282
, Issue.51
, pp. 36905-36913
-
-
Teichert, R.W.1
Jimenez, E.C.2
Twede, V.3
Watkins, M.4
Hollmann, M.5
Bulaj, G.6
-
29
-
-
33645822456
-
Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons
-
Thomas C.G., Miller A.J., Westbrook G.L. Synaptic and extrasynaptic NMDA receptor NR2 subunits in cultured hippocampal neurons. J Neurophysiol 2006, 95(3):1727-1734.
-
(2006)
J Neurophysiol
, vol.95
, Issue.3
, pp. 1727-1734
-
-
Thomas, C.G.1
Miller, A.J.2
Westbrook, G.L.3
-
30
-
-
0033562610
-
The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
-
Tovar K.R., Westbrook G.L. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro. J Neurosci 1999, 19(10):4180-4188.
-
(1999)
J Neurosci
, vol.19
, Issue.10
, pp. 4180-4188
-
-
Tovar, K.R.1
Westbrook, G.L.2
-
31
-
-
35948947269
-
On the hypes and falls in neuroprotection: targeting the NMDA receptor
-
Villmann C., Becker C.M. On the hypes and falls in neuroprotection: targeting the NMDA receptor. Neuroscientist 2007, 13(6):594-615.
-
(2007)
Neuroscientist
, vol.13
, Issue.6
, pp. 594-615
-
-
Villmann, C.1
Becker, C.M.2
-
32
-
-
34547228856
-
Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors
-
von Engelhardt J., Coserea I., Pawlak V., Fuchs E.C., Kohr G., Seeburg P.H., et al. Excitotoxicity in vitro by NR2A- and NR2B-containing NMDA receptors. Neuropharmacology 2007, 53(1):10-17.
-
(2007)
Neuropharmacology
, vol.53
, Issue.1
, pp. 10-17
-
-
von Engelhardt, J.1
Coserea, I.2
Pawlak, V.3
Fuchs, E.C.4
Kohr, G.5
Seeburg, P.H.6
-
33
-
-
0026047370
-
Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures
-
Vornov J.J., Tasker R.C., Coyle J.T. Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures. Exp Neurol 1991, 114(1):11-22.
-
(1991)
Exp Neurol
, vol.114
, Issue.1
, pp. 11-22
-
-
Vornov, J.J.1
Tasker, R.C.2
Coyle, J.T.3
-
34
-
-
0038171090
-
Trafficking of NMDA receptors
-
Wenthold R.J., Prybylowski K., Standley S., Sans N., Petralia R.S. Trafficking of NMDA receptors. Annu Rev Pharmacol Toxicol 2003, 43:335-358.
-
(2003)
Annu Rev Pharmacol Toxicol
, vol.43
, pp. 335-358
-
-
Wenthold, R.J.1
Prybylowski, K.2
Standley, S.3
Sans, N.4
Petralia, R.S.5
-
35
-
-
0033933764
-
Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-D-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies
-
Williams A.J., Dave J.R., Phillips J.B., Lin Y., McCabe R.T., Tortella F.C. Neuroprotective efficacy and therapeutic window of the high-affinity N-methyl-D-aspartate antagonist conantokin-G: in vitro (primary cerebellar neurons) and in vivo (rat model of transient focal brain ischemia) studies. J Pharmacol Exp Ther 2000, 294(1):378-386.
-
(2000)
J Pharmacol Exp Ther
, vol.294
, Issue.1
, pp. 378-386
-
-
Williams, A.J.1
Dave, J.R.2
Phillips, J.B.3
Lin, Y.4
McCabe, R.T.5
Tortella, F.C.6
-
36
-
-
0034845914
-
Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action
-
Williams K. Ifenprodil, a novel NMDA receptor antagonist: site and mechanism of action. Curr Drug Targets 2001, 2(3):285-298.
-
(2001)
Curr Drug Targets
, vol.2
, Issue.3
, pp. 285-298
-
-
Williams, K.1
-
37
-
-
0037183734
-
Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis
-
Williams A.J., Dave J.R., Lu X.M., Ling G., Tortella F.C. Selective NR2B NMDA receptor antagonists are protective against staurosporine-induced apoptosis. Eur J Pharmacol 2002, 452(1):135-136.
-
(2002)
Eur J Pharmacol
, vol.452
, Issue.1
, pp. 135-136
-
-
Williams, A.J.1
Dave, J.R.2
Lu, X.M.3
Ling, G.4
Tortella, F.C.5
-
38
-
-
0034798601
-
Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition
-
Wittekindt B., Malany S., Schemm R., Otvos L., Maccecchini M.L., Laube B., et al. Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition. Neuropharmacology 2001, 41(6):753-761.
-
(2001)
Neuropharmacology
, vol.41
, Issue.6
, pp. 753-761
-
-
Wittekindt, B.1
Malany, S.2
Schemm, R.3
Otvos, L.4
Maccecchini, M.L.5
Laube, B.6
-
39
-
-
56349135882
-
NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins
-
Xiao C., Huang Y., Dong M., Hu J., Hou S., Castellino F.J., et al. NR2B-selective conantokin peptide inhibitors of the NMDA receptor display enhanced antinociceptive properties compared to non-selective conantokins. Neuropeptides 2008, 42(5-6):601-609.
-
(2008)
Neuropeptides
, vol.42
, Issue.5-6
, pp. 601-609
-
-
Xiao, C.1
Huang, Y.2
Dong, M.3
Hu, J.4
Hou, S.5
Castellino, F.J.6
-
40
-
-
33645010267
-
Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors
-
Zhou M., Baudry M. Developmental changes in NMDA neurotoxicity reflect developmental changes in subunit composition of NMDA receptors. J Neurosci 2006, 26(11):2956-2963.
-
(2006)
J Neurosci
, vol.26
, Issue.11
, pp. 2956-2963
-
-
Zhou, M.1
Baudry, M.2
|