Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice

FEBS Journal

Volumn 278, Issue 9, 2011, Pages 1484-1492

  Zhang, Wei ^a   Lu, Dan ^a   Dong, Wei ^a   Zhang, Li ^a   Zhang, Xiaojuan ^a   Quan, Xiongzhi ^a   Ma, Chunmei ^b   Lian, Hong ^a   Zhang, Lianfeng ^a,c  

^a BEIJING HOSPITAL   (China)

^b PEKING UNION MEDICAL COLLEGE   (China)

^c Building 5 ^*  (China)

Author keywords

apoptosis; CYP2E1; dilated cardiomyopathy; oxidative stress; transgenic mice

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; CYTOCHROME P450 2E1; GLUTATHIONE; HYDROGEN PEROXIDE; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE;

ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEGENERATION; CONGESTIVE CARDIOMYOPATHY; CONTROLLED STUDY; CYTOSOL; FIBROSIS; GENE OVEREXPRESSION; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; MORTALITY; MOUSE; MUSCLE FIBRIL; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SIGNAL TRANSDUCTION; TISSUE SPECIFICITY; TRANSGENIC MOUSE; UPREGULATION;

ANIMALS; APOPTOSIS; CYTOCHROME P-450 CYP2E1; MICE; MICE, TRANSGENIC; MYOCARDIUM; OXIDATIVE STRESS;

MUS; MUS MUSCULUS;

EID: 79955060097     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2011.08063.x     Document Type: Article

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