Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats

Mediators of Inflammation

Volumn 2011, Issue , 2011, Pages

  Di, Qing ^a   Yu, Nian ^a   Liu, Hao ^b   Hu, Yong ^a   Jiang, Ying ^a   Yan, Yu Kui ^c   Zhang, Yan Fang ^a   Zhang, Ying Dong ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c HUZHOU CENTRAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; GLYCOPROTEIN P; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KAINIC ACID; PYRROLIDINE DITHIOCARBAMATE; TRANSCRIPTION FACTOR RELA;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; CELL SURVIVAL; HIPPOCAMPUS; MALE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE; ANIMAL; BRAIN; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DISEASE PREDISPOSITION; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BRAIN; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; KAINIC ACID; MALE; NF-KAPPA B; P-GLYCOPROTEIN; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; TRANSCRIPTION FACTOR RELA;

EID: 79955049801     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2011/670613     Document Type: Article

References (44)

1. Kwan P. Brodie M. J. Early identification of refractory epilepsy The New England Journal of Medicine 2000 342 5 314 319 (Pubitemid 30075244)
2. Lasson W. Mechanisms of drug resistance in epilepsy Przegld Lekarski 2006 63 11 1218 1220
3. Lscher W. Potschka H. Drug resistance in brain diseases and the role of drug efflux transporters Nature Reviews Neuroscience 2005 6 8 591 602 (Pubitemid 41059334)
4. Lazarowski A. Czornyj L. Lubienieki F. Girardi E. Vazquez S. D'Giano C. ABC transporters during epilepsy and mechanisms underlying multidrug resistance in refractory epilepsy Epilepsia 2007 48 5, supplement 140 149 (Pubitemid 47512215)
5. Gottesman M. M. Pastan I. Biochemistry of multidrug resistance mediated by the multidrug transporter Annual Review of Biochemistry 1993 62 385 427 (Pubitemid 23237876)
6. Roberts D. J. Goralski K. B. A critical overview of the influence of inflammation and infection on P-glycoprotein expression and activity in the brain Expert Opinion on Drug Metabolism and Toxicology 2008 4 10 1245 1264
7. Bauer B. Hartz A. M. S. Pekcec A. Toellner K. Miller D. S. Potschka H. Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling Molecular Pharmacology 2008 73 5 1444 1453 (Pubitemid 351574834)
8. Zibell G. Unkrer B. Pekcec A. Hartz A. M. S. Bauer B. Miller D. S. Potschka H. Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition Neuropharmacology 2009 56 5 849 855
9. van Vliet E. A. Zibell G. Pekcec A. Schlichtiger J. Edelbroek P. M. Holtman L. Aronica E. Gorter J. A. Potschka H. COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats Neuropharmacology 2010 58 2 404 412
10. Vallabhapurapu S. Karin M. Regulation and function of NF- B transcription factors in the immune system Annual Review of Immunology 2009 27 693 733
11. Matsuoka Y. Kitamura Y. Okazaki M. Terai K. Taniguchi T. Kainic acid-induced activation of nuclear factor- B in rat hippocampus Experimental Brain Research 1999 124 2 215 222 (Pubitemid 29134421)
12. Baldwin A. S. The NF- B and I B proteins: new discoveries and insights Annual Review of Immunology 1996 14 649 681
13. Liu H. Liu Z. H. Chen Z. H. Yang J. W. Li L. S. Triptolide: a potent inhibitor of NF- B in T-lymphocytes Acta Pharmacologica Sinica 2000 21 9 782 786
14. Ronaldson P. T. Ashraf T. Bendayan R. Regulation of multidrug resistance protein 1 by tumor necrosis factor in cultured glial cells: involvement of nuclear factor- B and c-Jun N-terminal kinase signaling pathways Molecular Pharmacology 2010 77 4 644 659
15. Garca M. G. Alaniz L. D. Cordo Russo R. I. Alvarez E. Hajos S. E. PI3K/Akt inhibition modulates multidrug resistance and activates NF- B in murine lymphoma cell lines Leukemia Research 2009 33 2 288 296
16. Maeng H. J. Kim M. H. Jin H. E. Sang M. S. Tsuruo T. Sang G. K. Kim D. D. Shim C. K. Chung S. J. Functional induction of P-glycoprotein in the blood-brain barrier of streptozotocin-induced diabetic rats: evidence for the involvement of nuclear factor- B, a nitrosative stress-sensitive transcription factor, in the regulation Drug Metabolism and Disposition 2007 35 11 1996 2005 (Pubitemid 350005189)
17. The Ministry of Science and Technology of the Peoples Republic of China Guidance Suggestions for the Care and Use of Laboratory Animals 2006 Beijing, China The Ministry of Science and Technology of the Peoples Republic of China
18. Paxino G. Watson C. The Rat Brain in Sterotaxic Coordinates 2005 5th London, UK Elsevier
19. Soerensen J. Pekcec A. Fuest C. Nickel A. Potschka H. Pyrrolidine dithiocarbamate protects the piriform cortex in the pilocarpine status epilepticus model Epilepsy Research 2009 87 2-3 177 183
20. Racine R. J. Modification of seizure activity by electrical stimulation: II. Motor seizure Electroencephalography and Clinical Neurophysiology 1972 32 3 281 294
21. Galic M. A. Riazi K. Henderson A. K. Tsutsui S. Pittman Q. J. Viral-like brain inflammation during development causes increased seizure susceptibility in adult rats Neurobiology of Disease 2009 36 2 343 351
22. Liu H. Li W. Ahmad M. Miller T. M. Rose M. E. Poloyac S. M. Uechi G. Balasubramani M. Hickey R. W. Graham S. H. Modification of ubiquitin-C-terminal hydrolase-L1 by cyclopentenone prostaglandins exacerbates hypoxic injury Neurobiology of Disease 2011 41 2 318 328
23. Schmitz C. Hof P. R. Design-based stereology in neuroscience Neuroscience 2005 130 4 813 831 (Pubitemid 40094616)
24. Lscher W. Potschka H. Blood-brain barrier active efflux transporters: ATP-binding cassette gene family NeuroRx 2005 2 1 86 98 (Pubitemid 40128029)
25. Luna-Torts C. Fedrowitz M. Lscher W. Several major antiepileptic drugs are substrates for human P-glycoprotein Neuropharmacology 2008 55 8 1364 1375
26. Volk H. Potschka H. Lscher W. Immunohistochemical localization of P-glycoprotein in rat brain and detection of its increased expression by seizures are sensitive to fixation and staining variables Journal of Histochemistry and Cytochemistry 2005 53 4 517 531 (Pubitemid 40463506)
27. van Vliet E. A. Van Schaik R. Edelbroek P. M. Voskuyl R. A. Redeker S. Aronica E. Wadman W. J. Gorter J. A. Region-specific overexpression of P-glycoprotein at the blood-brain barrier affects brain uptake of phenytoin in epileptic rats Journal of Pharmacology and Experimental Therapeutics 2007 322 1 141 147 (Pubitemid 46956371)
28. Deng X. Luyendyk J. P. Ganey P. E. Roth R. A. Inflammatory stress and idiosyncratic hepatotoxicity: hints from animal models Pharmacological Reviews 2009 61 3 262 282
29. Chen L. Cheng X. Tian L. Yang T. Hermann S. Zhou D. Inhibition of P-glycoprotein over-expression by shRNA-mdr1b in rat astrocytes Neurochemical Research 2009 34 3 411 417
30. Vezzani A. Granata T. Brain inflammation in epilepsy: experimental and clinical evidence Epilepsia 2005 46 11 1724 1743 (Pubitemid 44921957)
31. Choi J. Nordli D. R. Alden T. D. DiPatri A. Laux L. Kelley K. Rosenow J. Schuele S. U. Rajaram V. Koh S. Cellular injury and neuroinflammation in children with chronic intractable epilepsy Journal of Neuroinflammation 2009 6, article 38
32. Won S. J. Ko H. W. Kim E. Y. Park E. C. Huh K. Jung N. P. Choi I. Oh Y. K. Shin H. C. Gwag B. J. Nuclear factor kappa B-mediated kainate neurotoxicity in the rat and hamster hippocampus Neuroscience 1999 94 1 83 91 (Pubitemid 29457599)
33. Crespel A. Coubes P. Rousset M. C. Brana C. Rougier A. Rondouin G. Bockaert J. Baldy-Moulinier M. Lerner-Natoli M. Inflammatory reactions in human medial temporal lobe epilepsy with hippocampal sclerosis Brain Research 2002 952 2 159 169
34. Yu C. Argyropoulos G. Zhang Y. Kastin A. J. Hsuchou H. Pan W. Neuroinflammation activates Mdr1b efflux transport through NF B: promoter analysis in BBB endothelia Cellular Physiology and Biochemistry 2008 22 5-6 745 756
35. Kwan P. Brodie M. J. Potential role of drug transporters in the pathogenesis of medically intractable epilepsy Epilepsia 2005 46 2 224 235 (Pubitemid 40194666)
36. Hayakawa M. Miyashita H. Sakamoto I. Kitagawa M. Tanaka H. Yasuda H. Karin M. Kikugawa K. Evidence that reactive oxygen species do not mediate NF- B activation EMBO Journal 2003 22 13 3356 3366 (Pubitemid 36834865)
37. Bauer B. Hartz A. M. S. Miller D. S. Tumor necrosis factor and endothelin-1 increase p-glycoprotein expression and transport activity at the blood-brain barrier Molecular Pharmacology 2007 71 3 667 675 (Pubitemid 46294078)
38. Hartz A. M. S. Bauer B. Block M. L. Hong J. S. Miller D. S. Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier FASEB Journal 2008 22 8 2723 2733
39. Narang V. S. Fraga C. Kumar N. Shen J. Throm S. Stewart C. F. Waters C. M. Dexamethasone increases expression and activity of multidrug resistance transporters at the rat blood-brain barrier American Journal of Physiology 2008 295 2 C440 C450
40. Steinbrecher K. A. Wilson W. Cogswell P. C. Baldwin A. S. Glycogen synthase kinase 3 functions to specify gene-specific, NF- B-dependent transcription Molecular and Cellular Biology 2005 25 19 8444 8455 (Pubitemid 41369166)
41. Gong R. Rifai A. Ge Y. Chen S. Dworkin L. D. Hepatocyte growth factor suppresses proinflammatory NF B activation through GSK3 inactivation in renal tubular epithelial cells The Journal of Biological Chemistry 2008 283 12 7401 7410
42. Shin E. J. Jhoo J. H. Kim W. K. Jhoo W. K. Lee C. Jung B. D. Kim H. C. Protection against kainate neurotoxicity by pyrrolidine dithiocarbamate Clinical and Experimental Pharmacology and Physiology 2004 31 5-6 320 326 (Pubitemid 38803075)
43. Mattson M. P. Camandola S. NF- B in neuronal plasticity and neurodegenerative disorders Journal of Clinical Investigation 2001 107 3 247 254
44. Lubin F. D. Ren Y. Xu X. Anderson A. E. Nuclear factor- B regulates seizure threshold and gene transcription following convulsant stimulation Journal of Neurochemistry 2007 103 4 1381 1395 (Pubitemid 47631816)